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The map label for this gene is gmhA

Identifier: 146342064

GI number: 146342064

Start: 5417478

End: 5418074

Strand: Direct

Name: gmhA

Synonym: BRADO5204

Alternate gene names: 146342064

Gene position: 5417478-5418074 (Clockwise)

Preceding gene: 146342063

Following gene: 146342065

Centisome position: 72.65

GC content: 69.68

Gene sequence:

>597_bases
GTGACCGACGCACTGGACAGCCTGATCTCCAACCATCTCGCCCGCTCCCGCGCGGCGATGGAGCGCGCGGCTGTCGATGG
CGCACTTCTCGCCAGCGCCGAGCGGATCGCGACGGCGATCATCGGAGCGCTGCGCGGCGGCCACAAGCTGCTGATCGTCG
GCAATGGCGGCAGCGCGGCGGATGCGCAGCACATCGCGGCCGAGATCGTCGGCCGCTACAAGCAGGAGCGGCCCGCCTTT
GCGGCGATCGCGCTGACCACCGACACTTCGGCGCTGACCGCGATCGGCAATGATTACGGCTTCGATCACGTGTTCGCCCG
CCAGGTCGAGGGACTCGGCGCCAGCGGCGACGTGCTGCTGGCGATCTCGACCTCCGGCCGCTCGCCGAGCATCCTCAACG
CGCTGCGCAAGGCTCGCGAGCGCGGGCTGGTGACGATCGGCTTCACCGGCACCAACGGCCTTGGCATGGGTGAACTGTGC
GACGAGCTGCTGGTCGCGCCGAGCGACGATACGCCGCTGATCCAGCAGATCCACCTCGCCACCGCGCACGGCATCTGCGA
GACCATCGAGGCGGCGCTGATGCAGGACGCGCGCTAG

Upstream 100 bases:

>100_bases
CCAGCGCGTGCTGGCTGAGGCGGCGATCCCGGTCGCCCCCTAGCTTGCGCGGGGACGGCGCGCCCCCTACACCGGCCCTA
TCGCAATCCGAGCCGCCATC

Downstream 100 bases:

>100_bases
ATGACGACTCCTCAGCTCAAGCCCGCGGCGTTCCTCGATCGCGACGGCGTCATCAACCACGACGACAACTACATCGGCTC
GCCCGAGCGCATCCGCTGGA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTDALDSLISNHLARSRAAMERAAVDGALLASAERIATAIIGALRGGHKLLIVGNGGSAADAQHIAAEIVGRYKQERPAF
AAIALTTDTSALTAIGNDYGFDHVFARQVEGLGASGDVLLAISTSGRSPSILNALRKARERGLVTIGFTGTNGLGMGELC
DELLVAPSDDTPLIQQIHLATAHGICETIEAALMQDAR

Sequences:

>Translated_198_residues
MTDALDSLISNHLARSRAAMERAAVDGALLASAERIATAIIGALRGGHKLLIVGNGGSAADAQHIAAEIVGRYKQERPAF
AAIALTTDTSALTAIGNDYGFDHVFARQVEGLGASGDVLLAISTSGRSPSILNALRKARERGLVTIGFTGTNGLGMGELC
DELLVAPSDDTPLIQQIHLATAHGICETIEAALMQDAR
>Mature_197_residues
TDALDSLISNHLARSRAAMERAAVDGALLASAERIATAIIGALRGGHKLLIVGNGGSAADAQHIAAEIVGRYKQERPAFA
AIALTTDTSALTAIGNDYGFDHVFARQVEGLGASGDVLLAISTSGRSPSILNALRKARERGLVTIGFTGTNGLGMGELCD
ELLVAPSDDTPLIQQIHLATAHGICETIEAALMQDAR

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1786416, Length=189, Percent_Identity=38.0952380952381, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789539, Length=173, Percent_Identity=42.1965317919075, Blast_Score=128, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GMHA_BRASO (A4YYB9)

Other databases:

- EMBL:   CU234118
- RefSeq:   YP_001207112.1
- ProteinModelPortal:   A4YYB9
- SMR:   A4YYB9
- STRING:   A4YYB9
- GeneID:   5116984
- GenomeReviews:   CU234118_GR
- KEGG:   bra:BRADO5204
- eggNOG:   COG0279
- HOGENOM:   HBG671955
- OMA:   QEMHILI
- ProtClustDB:   PRK13937
- BioCyc:   BSP376:BRADO5204-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00067
- InterPro:   IPR020620
- InterPro:   IPR001347

Pfam domain/function: PF01380 SIS

EC number: =5.3.1.28

Molecular weight: Translated: 20483; Mature: 20351

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS51464 SIS

Important sites: BINDING 68-68 BINDING 128-128 BINDING 175-175

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDALDSLISNHLARSRAAMERAAVDGALLASAERIATAIIGALRGGHKLLIVGNGGSAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCH
DAQHIAAEIVGRYKQERPAFAAIALTTDTSALTAIGNDYGFDHVFARQVEGLGASGDVLL
HHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEE
AISTSGRSPSILNALRKARERGLVTIGFTGTNGLGMGELCDELLVAPSDDTPLIQQIHLA
EEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
TAHGICETIEAALMQDAR
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDALDSLISNHLARSRAAMERAAVDGALLASAERIATAIIGALRGGHKLLIVGNGGSAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCH
DAQHIAAEIVGRYKQERPAFAAIALTTDTSALTAIGNDYGFDHVFARQVEGLGASGDVLL
HHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEE
AISTSGRSPSILNALRKARERGLVTIGFTGTNGLGMGELCDELLVAPSDDTPLIQQIHLA
EEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
TAHGICETIEAALMQDAR
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA