Click here to switch to the map view.

The map label for this gene is arsC [H]

Identifier: 146341970

GI number: 146341970

Start: 5304123

End: 5304650

Strand: Reverse

Name: arsC [H]

Synonym: BRADO5106

Alternate gene names: 146341970

Gene position: 5304650-5304123 (Counterclockwise)

Preceding gene: 146341971

Following gene: 146341969

Centisome position: 71.14

GC content: 67.99

Gene sequence:

>528_bases
GTGCCTGACCGCATCTACAATGTCCTGTTCCTCTGCACCGGCAACTCGGCGCGCTCGGTGCTCGCCGAGTCGATCCTGCG
CAAGGACGGCGCCGGCCGCTTCCGCGCCTTCTCGGCCGGCAGCACGCCGAAGGGCGCGGTGCATCCGCTCGCGCTCGAAC
TGCTCCGGCGCATGGACTATCCGACCGCGGATCTGCGCTCGAAGAGCTGGACGGAGTTCGCGGTGGCCGGCGCGCCGGTG
ATGGATTTCGTCTTCACCGTTTGCGACAACGCGGCGGGCGAAGCCTGTCCGGTCTGGCCGGGACAGCCGATGACCGCGCA
TTGGGGCATCGAGGATCCCGCGGCCGCTGATGGCACCGAGCTGGAGAAGCTCGCGGCGTTCACCACCGCGTTCCGCTATC
TGAAGAACCGCATCGGCGCCTTCATCAATCTGCCGCTCGATCGCATCGACAATCTGTCGCTCGGCACGCGGCTGCGCGAG
ATCGGGCGCTCCGAAGGTGCGACGCAGCCGACGCCAAAGGCCGGATGA

Upstream 100 bases:

>100_bases
TTCCTGCTCAGGGATTGCTGCGGCGGCCGGCCGGAGGTCTGCGCGCCGCTGATCGAAAGTCTCACCCCGTGCTGTCCGCC
CAAGCGCAAGGAGAAGAGCC

Downstream 100 bases:

>100_bases
TGGCGACCTTCGATCTGCCGCGTCGCGTCGTCGCCGAGGCGCTCGGCACGGCCGTGCTCGTCGCCACCGTGGTCGGCTCC
GGCATCATGGCGGAGCGCCT

Product: putative arsenate reductase/arsC-like protein

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MPDRIYNVLFLCTGNSARSVLAESILRKDGAGRFRAFSAGSTPKGAVHPLALELLRRMDYPTADLRSKSWTEFAVAGAPV
MDFVFTVCDNAAGEACPVWPGQPMTAHWGIEDPAAADGTELEKLAAFTTAFRYLKNRIGAFINLPLDRIDNLSLGTRLRE
IGRSEGATQPTPKAG

Sequences:

>Translated_175_residues
MPDRIYNVLFLCTGNSARSVLAESILRKDGAGRFRAFSAGSTPKGAVHPLALELLRRMDYPTADLRSKSWTEFAVAGAPV
MDFVFTVCDNAAGEACPVWPGQPMTAHWGIEDPAAADGTELEKLAAFTTAFRYLKNRIGAFINLPLDRIDNLSLGTRLRE
IGRSEGATQPTPKAG
>Mature_174_residues
PDRIYNVLFLCTGNSARSVLAESILRKDGAGRFRAFSAGSTPKGAVHPLALELLRRMDYPTADLRSKSWTEFAVAGAPVM
DFVFTVCDNAAGEACPVWPGQPMTAHWGIEDPAAADGTELEKLAAFTTAFRYLKNRIGAFINLPLDRIDNLSLGTRLREI
GRSEGATQPTPKAG

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18942; Mature: 18811

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDRIYNVLFLCTGNSARSVLAESILRKDGAGRFRAFSAGSTPKGAVHPLALELLRRMDY
CCCHHEEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCC
PTADLRSKSWTEFAVAGAPVMDFVFTVCDNAAGEACPVWPGQPMTAHWGIEDPAAADGTE
CCCHHCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHH
LEKLAAFTTAFRYLKNRIGAFINLPLDRIDNLSLGTRLREIGRSEGATQPTPKAG
HHHHHHHHHHHHHHHHHHHHEEECCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PDRIYNVLFLCTGNSARSVLAESILRKDGAGRFRAFSAGSTPKGAVHPLALELLRRMDY
CCHHEEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCC
PTADLRSKSWTEFAVAGAPVMDFVFTVCDNAAGEACPVWPGQPMTAHWGIEDPAAADGTE
CCCHHCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHH
LEKLAAFTTAFRYLKNRIGAFINLPLDRIDNLSLGTRLREIGRSEGATQPTPKAG
HHHHHHHHHHHHHHHHHHHHEEECCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]