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The map label for this gene is mhpD [H]

Identifier: 146341907

GI number: 146341907

Start: 5231562

End: 5232353

Strand: Reverse

Name: mhpD [H]

Synonym: BRADO5041

Alternate gene names: 146341907

Gene position: 5232353-5231562 (Counterclockwise)

Preceding gene: 146341908

Following gene: 146341902

Centisome position: 70.17

GC content: 71.21

Gene sequence:

>792_bases
ATGGGAGCAGACGAGGTCCTTGCCGCCGCGCAATCGATCGTGGCCGCCCGCCGCGCGCGGACGCCGCTGGCGCCGCTGCC
GGCTCACCTTCAGCCGAAGGATGAAGCGGCTGGCTATGAGATCCAGCATGAGGCTCACTGGCTGCTCGCCGAGCATGCCG
GCGATTTCGCCGGCTACAAGATCGGCTGCACCAGCCAGGTGATGCAGGACTATATTGGCATTCCGCATCCTTGCGCCGGC
GGCGTCTTCGCGGGCGGCGTGCACGCCTCGGGTGTCACGCTGCGCGCGGCCGACTTCGTTCGCGTCGGCGTCGAATGCGA
GATCGCGGTGCGGCTGGCCAAGGACCTGCTGCCGCTGGACGCGCCGTTCACCATCGCCCATGTCGGCGACGCGATCGGCG
ACTGCCATGCGGCGATCGAGATCGTCGACGACCGCTACGTGCAATGGGAGACCATGGGCGCGCCGACCCTGGTGGCCGAC
GACTTCTTTGCCGCCGGCTGTGTGCTCGGTCCCGCCGTCCCGCGGGAAGCCGCCGGAGACCTCGCTGCCGTGCAGGGCCG
CGCCTTCGTGAACGACGCCCTGGCCGGGCAGGGCTCCGGCGCCGACGTGCTCGGCCATCCGCTGCACGCGCTCGCCTGGC
TCGCCAACCACCTCGCCTCCCGCGGCGACGGGCTCGAGGCCGGGCAGCTGGTGCTGACCGGCAGCCTGGTCAAGACGCTC
TGGCTCAAGCCGGGCGACCGGGTGCGGATGGAGCTGGACGGGCTGGGCGTGGTCGAGGCGGTGTTCGCGTGA

Upstream 100 bases:

>100_bases
CAGGAGATGAAGTGAGCGGCAAAAGCCGCGTCGTGACAACCTGTTAACCATAAGACCTCAGAGGCCGCTTGGAGCGGCCG
ACAGCGGGAGTTGAACGATC

Downstream 100 bases:

>100_bases
GGGCACGATAGAAAACAAGAATGCTGTGCCAGCCCGCAAGCCCCGCTGTCATCGCGCGGCTTGAGCCGGGGCAATCCAGG
ATGACGTGAGATCCCGGTTC

Product: putative hydratase/decarboxylase 4-oxalocrotonate decarboxylase

Products: NA

Alternate protein names: 2-hydroxypentadienoic acid hydratase [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MGADEVLAAAQSIVAARRARTPLAPLPAHLQPKDEAAGYEIQHEAHWLLAEHAGDFAGYKIGCTSQVMQDYIGIPHPCAG
GVFAGGVHASGVTLRAADFVRVGVECEIAVRLAKDLLPLDAPFTIAHVGDAIGDCHAAIEIVDDRYVQWETMGAPTLVAD
DFFAAGCVLGPAVPREAAGDLAAVQGRAFVNDALAGQGSGADVLGHPLHALAWLANHLASRGDGLEAGQLVLTGSLVKTL
WLKPGDRVRMELDGLGVVEAVFA

Sequences:

>Translated_263_residues
MGADEVLAAAQSIVAARRARTPLAPLPAHLQPKDEAAGYEIQHEAHWLLAEHAGDFAGYKIGCTSQVMQDYIGIPHPCAG
GVFAGGVHASGVTLRAADFVRVGVECEIAVRLAKDLLPLDAPFTIAHVGDAIGDCHAAIEIVDDRYVQWETMGAPTLVAD
DFFAAGCVLGPAVPREAAGDLAAVQGRAFVNDALAGQGSGADVLGHPLHALAWLANHLASRGDGLEAGQLVLTGSLVKTL
WLKPGDRVRMELDGLGVVEAVFA
>Mature_262_residues
GADEVLAAAQSIVAARRARTPLAPLPAHLQPKDEAAGYEIQHEAHWLLAEHAGDFAGYKIGCTSQVMQDYIGIPHPCAGG
VFAGGVHASGVTLRAADFVRVGVECEIAVRLAKDLLPLDAPFTIAHVGDAIGDCHAAIEIVDDRYVQWETMGAPTLVADD
FFAAGCVLGPAVPREAAGDLAAVQGRAFVNDALAGQGSGADVLGHPLHALAWLANHLASRGDGLEAGQLVLTGSLVKTLW
LKPGDRVRMELDGLGVVEAVFA

Specific function: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family. MhpD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=241, Percent_Identity=30.2904564315353, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.2.1.80 [H]

Molecular weight: Translated: 27328; Mature: 27197

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGADEVLAAAQSIVAARRARTPLAPLPAHLQPKDEAAGYEIQHEAHWLLAEHAGDFAGYK
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCEE
IGCTSQVMQDYIGIPHPCAGGVFAGGVHASGVTLRAADFVRVGVECEIAVRLAKDLLPLD
ECCHHHHHHHHCCCCCCCCCCCEECCEECCCEEEEEHHEEEECCCHHHHHHHHHHHCCCC
APFTIAHVGDAIGDCHAAIEIVDDRYVQWETMGAPTLVADDFFAAGCVLGPAVPREAAGD
CCEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHCCCCCCHHCCC
LAAVQGRAFVNDALAGQGSGADVLGHPLHALAWLANHLASRGDGLEAGQLVLTGSLVKTL
HHHHCCCHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHH
WLKPGDRVRMELDGLGVVEAVFA
HCCCCCEEEEEECCCCHHHHHCC
>Mature Secondary Structure 
GADEVLAAAQSIVAARRARTPLAPLPAHLQPKDEAAGYEIQHEAHWLLAEHAGDFAGYK
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCEE
IGCTSQVMQDYIGIPHPCAGGVFAGGVHASGVTLRAADFVRVGVECEIAVRLAKDLLPLD
ECCHHHHHHHHCCCCCCCCCCCEECCEECCCEEEEEHHEEEECCCHHHHHHHHHHHCCCC
APFTIAHVGDAIGDCHAAIEIVDDRYVQWETMGAPTLVADDFFAAGCVLGPAVPREAAGD
CCEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHCCCCCCHHCCC
LAAVQGRAFVNDALAGQGSGADVLGHPLHALAWLANHLASRGDGLEAGQLVLTGSLVKTL
HHHHCCCHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHH
WLKPGDRVRMELDGLGVVEAVFA
HCCCCCEEEEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA