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The map label for this gene is 146341873

Identifier: 146341873

GI number: 146341873

Start: 5196790

End: 5197458

Strand: Reverse

Name: 146341873

Synonym: BRADO5005

Alternate gene names: NA

Gene position: 5197458-5196790 (Counterclockwise)

Preceding gene: 146341874

Following gene: 146341868

Centisome position: 69.7

GC content: 60.39

Gene sequence:

>669_bases
ATGCCTGTCATCCCCTCGACCAAACCCTATCGCATCGGCCGCTCAAAGACGGGGCTCGGTCTGTTCGCCACCCAGCCGAT
CAAGAAGGGCACCAAGATCATCCGCTACTTCGGACCGCTGTTGGATTCGAAGAAGGCCGAGGACGATGCGATCGAGAACA
AATATCTGTTCGAGCTCGACAACCGCTGGACCATCGACGGCTCGGTCCGCGAGAACGTCGCCCGTTACATCAATCATTCG
TGCAAGCCGAACGCCGAGTCGGACGTCAAGCCGCGCAAGAAGAAGATCTTTATCCGCGCGATCAAGAACATCGCGCCGGG
CGAGGAGATCAATTACGATTACGGCACCGATTACTTCAAAGCCTATCTGAAGCCGATCGGCTGCAAATGCGACGCCTGCG
AGAAGAAGCGGGCGAAGAAGAAGGCCGAGGCGCGCGCGGAGCGCGCCAAGCAAAAGGCCAAGGACGAGCGGAAGGCCGCG
AAGAAGGCCAAGAAGAAAGCCAAGAAAACGTCCGACAAGCTTCCCAAAGAGACGGTCAAGTCCAAGCAGCGCGTGAAAGC
GAAGACCTCAACGCGGGCCAAGGCGGAGAGCCGCCGGCCGGCTGCCGGCAAGCGCGTCAAGACCAAGTCCAGCCCCGCGA
AGACCCTGACCCGCGCCAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
AAGCTGGGGACGGCGCGAAACAGGGCAGGGAAACACCTGACAGCGCCGTGAATTTATCCTAGAACGTCCACCTCGCGAGG
TCCATCTCTTCCCATAGATC

Downstream 100 bases:

>100_bases
TCGGGCGAGCTCGCGTCCAGCGCCGCTCATCCCGGTTTGCTGAACGCAAGCGTCGTCCAGGTCACTCCCGCAGCCCGGTT
TTCTCTGTTCAGCGACGCGC

Product: histone-lysine N-methyltransferase

Products: NA

Alternate protein names: SET Domain-Containing Protein; Histone-Lysine N-Methyltransferase; Set Domain Protein; HistoNe-Lysine N-Methyltransferase H3 Lysine-4 Specific; SET Domain Protein; Setd1a Protein; Nuclear Protein Set; Zinc Finger Protein

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MPVIPSTKPYRIGRSKTGLGLFATQPIKKGTKIIRYFGPLLDSKKAEDDAIENKYLFELDNRWTIDGSVRENVARYINHS
CKPNAESDVKPRKKKIFIRAIKNIAPGEEINYDYGTDYFKAYLKPIGCKCDACEKKRAKKKAEARAERAKQKAKDERKAA
KKAKKKAKKTSDKLPKETVKSKQRVKAKTSTRAKAESRRPAAGKRVKTKSSPAKTLTRAKAA

Sequences:

>Translated_222_residues
MPVIPSTKPYRIGRSKTGLGLFATQPIKKGTKIIRYFGPLLDSKKAEDDAIENKYLFELDNRWTIDGSVRENVARYINHS
CKPNAESDVKPRKKKIFIRAIKNIAPGEEINYDYGTDYFKAYLKPIGCKCDACEKKRAKKKAEARAERAKQKAKDERKAA
KKAKKKAKKTSDKLPKETVKSKQRVKAKTSTRAKAESRRPAAGKRVKTKSSPAKTLTRAKAA
>Mature_221_residues
PVIPSTKPYRIGRSKTGLGLFATQPIKKGTKIIRYFGPLLDSKKAEDDAIENKYLFELDNRWTIDGSVRENVARYINHSC
KPNAESDVKPRKKKIFIRAIKNIAPGEEINYDYGTDYFKAYLKPIGCKCDACEKKRAKKKAEARAERAKQKAKDERKAAK
KAKKKAKKTSDKLPKETVKSKQRVKAKTSTRAKAESRRPAAGKRVKTKSSPAKTLTRAKAA

Specific function: Unknown

COG id: COG2940

COG function: function code R; Proteins containing SET domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI56550039, Length=123, Percent_Identity=34.9593495934959, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI91718902, Length=135, Percent_Identity=36.2962962962963, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI156142197, Length=155, Percent_Identity=32.9032258064516, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI156142199, Length=155, Percent_Identity=32.9032258064516, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI110349788, Length=121, Percent_Identity=32.2314049586777, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI224465233, Length=151, Percent_Identity=30.4635761589404, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI13699811, Length=165, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71993684, Length=128, Percent_Identity=37.5, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17552316, Length=124, Percent_Identity=37.0967741935484, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17552318, Length=124, Percent_Identity=37.0967741935484, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17552320, Length=124, Percent_Identity=37.0967741935484, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193210440, Length=133, Percent_Identity=36.8421052631579, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17565204, Length=120, Percent_Identity=35, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321911, Length=135, Percent_Identity=31.8518518518519, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18543183, Length=140, Percent_Identity=32.8571428571429, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281360813, Length=136, Percent_Identity=33.8235294117647, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641786, Length=136, Percent_Identity=33.8235294117647, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639197, Length=134, Percent_Identity=36.5671641791045, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28571451, Length=134, Percent_Identity=36.5671641791045, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI62472551, Length=126, Percent_Identity=34.9206349206349, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17136558, Length=126, Percent_Identity=34.9206349206349, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19550181, Length=126, Percent_Identity=34.9206349206349, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19550184, Length=126, Percent_Identity=34.9206349206349, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17136556, Length=126, Percent_Identity=34.9206349206349, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25015; Mature: 24884

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: PS50280 SET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVIPSTKPYRIGRSKTGLGLFATQPIKKGTKIIRYFGPLLDSKKAEDDAIENKYLFELD
CCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEC
NRWTIDGSVRENVARYINHSCKPNAESDVKPRKKKIFIRAIKNIAPGEEINYDYGTDYFK
CEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
AYLKPIGCKCDACEKKRAKKKAEARAERAKQKAKDERKAAKKAKKKAKKTSDKLPKETVK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SKQRVKAKTSTRAKAESRRPAAGKRVKTKSSPAKTLTRAKAA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
PVIPSTKPYRIGRSKTGLGLFATQPIKKGTKIIRYFGPLLDSKKAEDDAIENKYLFELD
CCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEC
NRWTIDGSVRENVARYINHSCKPNAESDVKPRKKKIFIRAIKNIAPGEEINYDYGTDYFK
CEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
AYLKPIGCKCDACEKKRAKKKAEARAERAKQKAKDERKAAKKAKKKAKKTSDKLPKETVK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SKQRVKAKTSTRAKAESRRPAAGKRVKTKSSPAKTLTRAKAA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA