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The map label for this gene is cobC [H]

Identifier: 146341798

GI number: 146341798

Start: 5117189

End: 5117782

Strand: Reverse

Name: cobC [H]

Synonym: BRADO4917

Alternate gene names: 146341798

Gene position: 5117782-5117189 (Counterclockwise)

Preceding gene: 146341799

Following gene: 146341797

Centisome position: 68.63

GC content: 68.35

Gene sequence:

>594_bases
ATGCGGCTCGACCTGCTGCGGCATGGCACCACCGGGCGCAACGGCCATCTCGACGGCCGCACCGATCCCCCGCTGAGCGA
GGCGGGTTGGGAGCAATTCCGGCGGCAGACTCGAAGCGGGGAATGGAGCCGGGTCGTGAGTTCCCCATTGATGCGAGCGC
GGGCGGCGGCGGACGAATATGCCCGACAGGCCGGCTGCGCGCTGCAGGTTGATCCAGATTGGAGCGAACTGCATTTCGGA
CAATGGGACGGGCGCAAGCGCAGCGACATCGTGAGTGAACCGGAGCAGGCCGCCTTGCTCGATGCCTTCTACGCGGATCC
CTTGGTCGCCGCACCCGGCGGCGAGAGCTGGGCCGATCTGCAAGTACGGGTGTCGCGCGCCGTGGATCGCATCCTCGCGA
CGGCGGAGCCTGCGGCGGTTCTGGTCGTCACGCATGGCGGCGCGATCCGCGCTGCGCTGTCGCATCTGCTCGGCTGGCCC
TTGCCTCAACTCTGGAGCTTGCGCATTCATCCCGGCACCCGTCTGACGCTCGAGGCTGGGCACGGCCCGGATGGCGCGCC
GTGGGCCGAAATCGTCGAGATCATCCAGCCATGA

Upstream 100 bases:

>100_bases
CGGGCGCTGCGACGGCGCTACCGATCCTGAGGCTCGCCTGCGCGCTTCACAACGGCATGGCCACCTTCGCGGAGGCGGCT
GTCTCGGGACGCGAGGCCTG

Downstream 100 bases:

>100_bases
GCCTGCGTGAATTCTGGATCGCTCTGCAGTTCCTGACGCGTCTGCCGACACCGCGTGTGGCGGAGTCCCGGCCCGACGAT
CTCGCGCGGGCGTCGGTATG

Product: putative Alpha-ribazole phosphatase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MRLDLLRHGTTGRNGHLDGRTDPPLSEAGWEQFRRQTRSGEWSRVVSSPLMRARAAADEYARQAGCALQVDPDWSELHFG
QWDGRKRSDIVSEPEQAALLDAFYADPLVAAPGGESWADLQVRVSRAVDRILATAEPAAVLVVTHGGAIRAALSHLLGWP
LPQLWSLRIHPGTRLTLEAGHGPDGAPWAEIVEIIQP

Sequences:

>Translated_197_residues
MRLDLLRHGTTGRNGHLDGRTDPPLSEAGWEQFRRQTRSGEWSRVVSSPLMRARAAADEYARQAGCALQVDPDWSELHFG
QWDGRKRSDIVSEPEQAALLDAFYADPLVAAPGGESWADLQVRVSRAVDRILATAEPAAVLVVTHGGAIRAALSHLLGWP
LPQLWSLRIHPGTRLTLEAGHGPDGAPWAEIVEIIQP
>Mature_197_residues
MRLDLLRHGTTGRNGHLDGRTDPPLSEAGWEQFRRQTRSGEWSRVVSSPLMRARAAADEYARQAGCALQVDPDWSELHFG
QWDGRKRSDIVSEPEQAALLDAFYADPLVAAPGGESWADLQVRVSRAVDRILATAEPAAVLVVTHGGAIRAALSHLLGWP
LPQLWSLRIHPGTRLTLEAGHGPDGAPWAEIVEIIQP

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=179, Percent_Identity=29.608938547486, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 21569; Mature: 21569

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDLLRHGTTGRNGHLDGRTDPPLSEAGWEQFRRQTRSGEWSRVVSSPLMRARAAADEY
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ARQAGCALQVDPDWSELHFGQWDGRKRSDIVSEPEQAALLDAFYADPLVAAPGGESWADL
HHHCCCEEEECCCHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCEEECCCCCCHHHH
QVRVSRAVDRILATAEPAAVLVVTHGGAIRAALSHLLGWPLPQLWSLRIHPGTRLTLEAG
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCHHEEEEECCCCEEEEECC
HGPDGAPWAEIVEIIQP
CCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MRLDLLRHGTTGRNGHLDGRTDPPLSEAGWEQFRRQTRSGEWSRVVSSPLMRARAAADEY
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ARQAGCALQVDPDWSELHFGQWDGRKRSDIVSEPEQAALLDAFYADPLVAAPGGESWADL
HHHCCCEEEECCCHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCEEECCCCCCHHHH
QVRVSRAVDRILATAEPAAVLVVTHGGAIRAALSHLLGWPLPQLWSLRIHPGTRLTLEAG
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCHHEEEEECCCCEEEEECC
HGPDGAPWAEIVEIIQP
CCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]