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The map label for this gene is cobL [H]

Identifier: 146341782

GI number: 146341782

Start: 5100563

End: 5101798

Strand: Reverse

Name: cobL [H]

Synonym: BRADO4901

Alternate gene names: 146341782

Gene position: 5101798-5100563 (Counterclockwise)

Preceding gene: 146341784

Following gene: 146341781

Centisome position: 68.42

GC content: 68.85

Gene sequence:

>1236_bases
ATGGTGAGTCCAAACGCAACCTGCAACGCGCCGCGCTGGCTGTCCATCATCGGGATCGGTGAGGACGGCGTTGACGGTCT
CTCTACGCCCGCGCGTGACCTGATTGCCAGCGCGACCTTCGTGGTCGGCGGCGCGCGTCATCTTGAGCTCGCTGCGCCGC
TCATCAGGTCGGAGCGGCTCGCATGGCCGAGCCCGCTGCACCTGGCGTTCGAGCAGATCGCAGCACGCCAGGGGCAGCCC
GTCGTGGTGCTGGCCAGCGGTGATCCCTTCAACTACGGCGTCGGCAAGCAGCTGATGCAACGCTTTGCACCCGCGGAGAT
GCTGTGCCTGCCGCATGCTTCGGCCTTCAGTCTCGCCGCGGCACGGCTCGGCTGGCCGCTGCAGGATGTCGCCCAGGTGA
CGCTGCATGGCCGCGCGCTCGAAGGCATCATTCGCCATCTCGCGCCGGGCGCACGCATCCTCGCGCTGGCTTGGGACGGA
TCTACGGCCGCAAAACTCGCCGGACTGCTGACCGCGCGCCGCATGGGCCGTTCGCGGTTGACCGCGCTCGAAGCCATGGG
CGGGACGCAGGAGCGTGTGCGCAGCGTGAGGGCCGACGAGTTCGACCTGTCCGATATCCATCCGCTCACGACGCTGGCGC
TGGAGATTGATGTCCAACCCGGTGCGCCGGTGATCCCGCTGACGTCGGGCCTCGCTGATGACCTGTTCGAGCATGACGGC
CAGCTCACAAAACGTGACGTCCGCGCCGCGACGCTGTCGGCACTCGCGCCGACGCCCGGCGAGCTGCTGTGGGATGTCGG
TCTCGGCTCCGGCTCGGTTGCGATCGAATGGCTGTTGCGTCATGGCTCGCTGCGCGCATTCGGCATCGAGGCGCGGCAGG
ACCGTGCGGATCGGGCCATGCGGAACGCGCTTGCGCTCGGTGCGCCCGACCTCCAGGTGGTGGTCGGCCGCGCGCCGACG
GCGCTGGCTGATCTCGAACCGCCGGATGCGATCTTCATCGGCGGCGGCATTTCGGAAGCTGGGGTGTTCGAGGCGGCCTG
GTCGCGCCTGAAGCCGGGCGGGCGGCTGGTCGCCAATGTCATCTCGCTCGAAGGCGAGGCGCGGTTGATCGATCTGTTCG
GCCGTCACGGCGGCGAACTGATGCGCATCGCGGTGTCGCGCATCGAGCCCGTCGGCCGCATGCACGGCTGGCGGCAGGCC
ATGCCGGTGACCCAATGGCGGGTGAGCAAGCCATGA

Upstream 100 bases:

>100_bases
AGCGTCGTGTCGAACCGGCGGTCGCCGGCCAGGAGCTGTGCCAACTCGGACGCCTCGGTGGTACCGCCGAGTATGAGAAT
GCGCATGCGGGGCTGGATCC

Downstream 100 bases:

>100_bases
TCGCGCTCGGCATCGGCTGCCGCCGCGACGCGAGCCTCTATGCGATCGAGAACGTGATCGCGCAAGCGCTGAGCGCTGCG
AAGCTCGTCGTCGATGACAT

Product: precorrin-6Y C(5,15)-methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MVSPNATCNAPRWLSIIGIGEDGVDGLSTPARDLIASATFVVGGARHLELAAPLIRSERLAWPSPLHLAFEQIAARQGQP
VVVLASGDPFNYGVGKQLMQRFAPAEMLCLPHASAFSLAAARLGWPLQDVAQVTLHGRALEGIIRHLAPGARILALAWDG
STAAKLAGLLTARRMGRSRLTALEAMGGTQERVRSVRADEFDLSDIHPLTTLALEIDVQPGAPVIPLTSGLADDLFEHDG
QLTKRDVRAATLSALAPTPGELLWDVGLGSGSVAIEWLLRHGSLRAFGIEARQDRADRAMRNALALGAPDLQVVVGRAPT
ALADLEPPDAIFIGGGISEAGVFEAAWSRLKPGGRLVANVISLEGEARLIDLFGRHGGELMRIAVSRIEPVGRMHGWRQA
MPVTQWRVSKP

Sequences:

>Translated_411_residues
MVSPNATCNAPRWLSIIGIGEDGVDGLSTPARDLIASATFVVGGARHLELAAPLIRSERLAWPSPLHLAFEQIAARQGQP
VVVLASGDPFNYGVGKQLMQRFAPAEMLCLPHASAFSLAAARLGWPLQDVAQVTLHGRALEGIIRHLAPGARILALAWDG
STAAKLAGLLTARRMGRSRLTALEAMGGTQERVRSVRADEFDLSDIHPLTTLALEIDVQPGAPVIPLTSGLADDLFEHDG
QLTKRDVRAATLSALAPTPGELLWDVGLGSGSVAIEWLLRHGSLRAFGIEARQDRADRAMRNALALGAPDLQVVVGRAPT
ALADLEPPDAIFIGGGISEAGVFEAAWSRLKPGGRLVANVISLEGEARLIDLFGRHGGELMRIAVSRIEPVGRMHGWRQA
MPVTQWRVSKP
>Mature_411_residues
MVSPNATCNAPRWLSIIGIGEDGVDGLSTPARDLIASATFVVGGARHLELAAPLIRSERLAWPSPLHLAFEQIAARQGQP
VVVLASGDPFNYGVGKQLMQRFAPAEMLCLPHASAFSLAAARLGWPLQDVAQVTLHGRALEGIIRHLAPGARILALAWDG
STAAKLAGLLTARRMGRSRLTALEAMGGTQERVRSVRADEFDLSDIHPLTTLALEIDVQPGAPVIPLTSGLADDLFEHDG
QLTKRDVRAATLSALAPTPGELLWDVGLGSGSVAIEWLLRHGSLRAFGIEARQDRADRAMRNALALGAPDLQVVVGRAPT
ALADLEPPDAIFIGGGISEAGVFEAAWSRLKPGGRLVANVISLEGEARLIDLFGRHGGELMRIAVSRIEPVGRMHGWRQA
MPVTQWRVSKP

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43777; Mature: 43777

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSPNATCNAPRWLSIIGIGEDGVDGLSTPARDLIASATFVVGGARHLELAAPLIRSERL
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHEECCCHHHHHHHHHHHHCCC
AWPSPLHLAFEQIAARQGQPVVVLASGDPFNYGVGKQLMQRFAPAEMLCLPHASAFSLAA
CCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCHHEEECCCCHHHHHHH
ARLGWPLQDVAQVTLHGRALEGIIRHLAPGARILALAWDGSTAAKLAGLLTARRMGRSRL
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
TALEAMGGTQERVRSVRADEFDLSDIHPLTTLALEIDVQPGAPVIPLTSGLADDLFEHDG
HHHHHCCCCHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCEEECCCCHHHHHHHCCC
QLTKRDVRAATLSALAPTPGELLWDVGLGSGSVAIEWLLRHGSLRAFGIEARQDRADRAM
CHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHH
RNALALGAPDLQVVVGRAPTALADLEPPDAIFIGGGISEAGVFEAAWSRLKPGGRLVANV
HHHHHCCCCCEEEEECCCCCHHCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHH
ISLEGEARLIDLFGRHGGELMRIAVSRIEPVGRMHGWRQAMPVTQWRVSKP
HHCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCEECCCC
>Mature Secondary Structure
MVSPNATCNAPRWLSIIGIGEDGVDGLSTPARDLIASATFVVGGARHLELAAPLIRSERL
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHEECCCHHHHHHHHHHHHCCC
AWPSPLHLAFEQIAARQGQPVVVLASGDPFNYGVGKQLMQRFAPAEMLCLPHASAFSLAA
CCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCHHEEECCCCHHHHHHH
ARLGWPLQDVAQVTLHGRALEGIIRHLAPGARILALAWDGSTAAKLAGLLTARRMGRSRL
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
TALEAMGGTQERVRSVRADEFDLSDIHPLTTLALEIDVQPGAPVIPLTSGLADDLFEHDG
HHHHHCCCCHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCEEECCCCHHHHHHHCCC
QLTKRDVRAATLSALAPTPGELLWDVGLGSGSVAIEWLLRHGSLRAFGIEARQDRADRAM
CHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHH
RNALALGAPDLQVVVGRAPTALADLEPPDAIFIGGGISEAGVFEAAWSRLKPGGRLVANV
HHHHHCCCCCEEEEECCCCCHHCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHH
ISLEGEARLIDLFGRHGGELMRIAVSRIEPVGRMHGWRQAMPVTQWRVSKP
HHCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]