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The map label for this gene is cyoB [C]

Identifier: 146341761

GI number: 146341761

Start: 5079265

End: 5081265

Strand: Reverse

Name: cyoB [C]

Synonym: BRADO4878

Alternate gene names: 146341761

Gene position: 5081265-5079265 (Counterclockwise)

Preceding gene: 146341762

Following gene: 146341752

Centisome position: 68.14

GC content: 61.47

Gene sequence:

>2001_bases
ATGCTTGGCAAGCTCACGTGGTCGGCGATTCCGTTCGGCCAGCCGATCCCGCTGGTGGCCGCAGGGATCGTGCTGCTCGT
CATCCTTGCTGTTCTGGTCTGGGTCTTCGCGAAGGGCCACTTTCCCTATCTCTGGCGCGAATGGATCACGAGCGTCGACC
ACAAGCGGATCGGCGTGATGTACATCTTCCTGGCGTTCGTGATGCTGCTCCGCGGCGGCACGGATGCCATCATGATGCGC
ACGCAACAGGCGGTCGCATTCCACTCCAACGGCTATCTCCCGCCGGAGCACTACAACCAGATCTTCTCGGCGCACGGCAC
GATCATGATCTTTTTCGTCGCGATGCCGTTCGTCATCGGGTTGATGAATCTCGTCGTGCCGTTGCAGCTCGGCGTCCGCG
ACGTCGCTTTTCCGACGCTGAATTCCGTCGGTTTCTGGCTGACGGCGACGGGCGCGCTGCTGGTCAACGTCTCGCTCGTG
GTCGGCGAGTTCGCCCGCACAGGCTGGCTGCCGTTCCCGCCGCTGTCGGAGCTCACATACTCGCCCGGGGTGGGCGTGGA
TTACTACATCTGGGCGCTGGAGATATCCGGCGTGGGAACGCTGGTCTCCGGCATCAATCTCGTCACGACCGTCTTGAAGC
TGCGGACGCAAGGCATGAGCTATCTGCGCATGCCGATGTTCTGCTGGACCACGCTCGCGTCCAATCTGCTGATCGTCGCG
GCCTTCCCGATCTTGACGGCGACGCTGACAATGCTGATGCTGGACCGCTATTTTGGCTTCCACTTCTTCACGAACGAGGC
CGGTGGCAACATGATGATGTTCATGAACCTGATCTGGGCCTGGGGGCATCCCGAGGTCTACATTCTGGTTCTGCCTGCAT
TCGGTATCTATTCCGAGGTGGTCGCGACGTTCTCGAGCAAGTCGCTGTTCGGCTATCGCTCGATGGTGCTGGCGACAATG
GCGATCTGCGTCGTGTCCTTCATGGTCTGGCTGCATCATTTCTTCACGATGGGCGCCGGGCCGGACGTCAACGCGATCTT
CGGCATCGCCAGCATGATCATCGCGGTGCCGACCGGCGTGAAGATCTACAACTGGCTGTTCACGATGTATGGCGGGCGAG
TGCGCTTCACGACGCCGATGCTGTGGTCGGTGGGCTTCATGATCACCTTCATGATCGGCGGACTGACGGGTGTGCTGGTT
GCCGTGCCGCCGGCCGACTTCCTGCTGCACAACAGCCTGTTTTTGGTGGCGCATTTCCACAATGTAATCATCGGCGGCGT
GCTGTTCGGTGCGTTCGCGGGCGTCACCTACTGGTTTCCGAAGGCCTTCGGGTTTCGTCTGTATGAGAGCTGGGGCAAGG
CGGCATTCTGGTTCACCTTGACCGGATTCTACGTCACGTTCATGCCGCTCTATGTGGTCGGTCTGCTCGGGATGACCCGG
CGCATGCAGCACTACGACGTCGCCGAGTGGCGTCCATGGCTGGCAGCGGCCACGGTCGGCACGGCGCTGCTCGCGATCGG
CGTGATTCTGCAGATCCTCCAGCTCGTCTTCAGCATACGCGACCGCGCGCTGTTGCGTGACACGACCGGCGACCCCTGGG
ATGGCCGCTCGCTCGAATGGGCCACCTCGTCACCGCCGCCGGTCTTCAACTTCGCGGTGCTGCCGAACGTGACGGGGCAG
GATGCATATTGGCGGATCAAGGAAAACGCCAAAAACCAGCAGCGTCAGACAAGGGACAGGGACTATCAGGACATCGAGCT
GCCGAAAAACTCCCCGACCGGCTTCGTCTGCGCGTTCTTTGCCACCGTGATGGGCTTCGCACTGATCTGGCATATCTGGT
GGATGGTCGCGCTTGGCGCAATAGGGGCGTTCGCGACATTCGTCGTGTTCGCCTGGCGCGATCATGATGAGTACGTCATC
CCGGCGGCGGAGGTGGCTCGGATCGATCGGCGGATCATCGAAGCGCGGGAGCGATTTTCGACCGCGGCTGGTGACGCCTG
A

Upstream 100 bases:

>100_bases
CGCCGTGGGACTTGGCGGACTGGCTCTCATGCTGATCGCACGAAGTCGCAGCGGGCGTCCAGCGCCGCGCGCCCGCGCGC
ACCGCTGATTGGGAGGCCGC

Downstream 100 bases:

>100_bases
ACGCGATCGACAGGTGCGGGCAGGACTGCTGACCGCACCTGTCGGGTCACATCACCAGCGATGATGCGTGCGGATCACGC
CATGGCCATGGCGGTGGCCG

Product: cytochrome o ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome c oxidase polypeptide I; Fourth terminal oxidase [H]

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MLGKLTWSAIPFGQPIPLVAAGIVLLVILAVLVWVFAKGHFPYLWREWITSVDHKRIGVMYIFLAFVMLLRGGTDAIMMR
TQQAVAFHSNGYLPPEHYNQIFSAHGTIMIFFVAMPFVIGLMNLVVPLQLGVRDVAFPTLNSVGFWLTATGALLVNVSLV
VGEFARTGWLPFPPLSELTYSPGVGVDYYIWALEISGVGTLVSGINLVTTVLKLRTQGMSYLRMPMFCWTTLASNLLIVA
AFPILTATLTMLMLDRYFGFHFFTNEAGGNMMMFMNLIWAWGHPEVYILVLPAFGIYSEVVATFSSKSLFGYRSMVLATM
AICVVSFMVWLHHFFTMGAGPDVNAIFGIASMIIAVPTGVKIYNWLFTMYGGRVRFTTPMLWSVGFMITFMIGGLTGVLV
AVPPADFLLHNSLFLVAHFHNVIIGGVLFGAFAGVTYWFPKAFGFRLYESWGKAAFWFTLTGFYVTFMPLYVVGLLGMTR
RMQHYDVAEWRPWLAAATVGTALLAIGVILQILQLVFSIRDRALLRDTTGDPWDGRSLEWATSSPPPVFNFAVLPNVTGQ
DAYWRIKENAKNQQRQTRDRDYQDIELPKNSPTGFVCAFFATVMGFALIWHIWWMVALGAIGAFATFVVFAWRDHDEYVI
PAAEVARIDRRIIEARERFSTAAGDA

Sequences:

>Translated_666_residues
MLGKLTWSAIPFGQPIPLVAAGIVLLVILAVLVWVFAKGHFPYLWREWITSVDHKRIGVMYIFLAFVMLLRGGTDAIMMR
TQQAVAFHSNGYLPPEHYNQIFSAHGTIMIFFVAMPFVIGLMNLVVPLQLGVRDVAFPTLNSVGFWLTATGALLVNVSLV
VGEFARTGWLPFPPLSELTYSPGVGVDYYIWALEISGVGTLVSGINLVTTVLKLRTQGMSYLRMPMFCWTTLASNLLIVA
AFPILTATLTMLMLDRYFGFHFFTNEAGGNMMMFMNLIWAWGHPEVYILVLPAFGIYSEVVATFSSKSLFGYRSMVLATM
AICVVSFMVWLHHFFTMGAGPDVNAIFGIASMIIAVPTGVKIYNWLFTMYGGRVRFTTPMLWSVGFMITFMIGGLTGVLV
AVPPADFLLHNSLFLVAHFHNVIIGGVLFGAFAGVTYWFPKAFGFRLYESWGKAAFWFTLTGFYVTFMPLYVVGLLGMTR
RMQHYDVAEWRPWLAAATVGTALLAIGVILQILQLVFSIRDRALLRDTTGDPWDGRSLEWATSSPPPVFNFAVLPNVTGQ
DAYWRIKENAKNQQRQTRDRDYQDIELPKNSPTGFVCAFFATVMGFALIWHIWWMVALGAIGAFATFVVFAWRDHDEYVI
PAAEVARIDRRIIEARERFSTAAGDA
>Mature_666_residues
MLGKLTWSAIPFGQPIPLVAAGIVLLVILAVLVWVFAKGHFPYLWREWITSVDHKRIGVMYIFLAFVMLLRGGTDAIMMR
TQQAVAFHSNGYLPPEHYNQIFSAHGTIMIFFVAMPFVIGLMNLVVPLQLGVRDVAFPTLNSVGFWLTATGALLVNVSLV
VGEFARTGWLPFPPLSELTYSPGVGVDYYIWALEISGVGTLVSGINLVTTVLKLRTQGMSYLRMPMFCWTTLASNLLIVA
AFPILTATLTMLMLDRYFGFHFFTNEAGGNMMMFMNLIWAWGHPEVYILVLPAFGIYSEVVATFSSKSLFGYRSMVLATM
AICVVSFMVWLHHFFTMGAGPDVNAIFGIASMIIAVPTGVKIYNWLFTMYGGRVRFTTPMLWSVGFMITFMIGGLTGVLV
AVPPADFLLHNSLFLVAHFHNVIIGGVLFGAFAGVTYWFPKAFGFRLYESWGKAAFWFTLTGFYVTFMPLYVVGLLGMTR
RMQHYDVAEWRPWLAAATVGTALLAIGVILQILQLVFSIRDRALLRDTTGDPWDGRSLEWATSSPPPVFNFAVLPNVTGQ
DAYWRIKENAKNQQRQTRDRDYQDIELPKNSPTGFVCAFFATVMGFALIWHIWWMVALGAIGAFATFVVFAWRDHDEYVI
PAAEVARIDRRIIEARERFSTAAGDA

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. This Ubiquinol Oxidase Shows Proton Pump Activity Across The Membrane In Addition To The Electron T

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=36.5949119373777, Blast_Score=315, Evalue=1e-85,
Organism=Escherichia coli, GI1786634, Length=666, Percent_Identity=58.5585585585586, Blast_Score=824, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=530, Percent_Identity=36.2264150943396, Blast_Score=332, Evalue=8e-92,
Organism=Saccharomyces cerevisiae, GI6226524, Length=326, Percent_Identity=38.9570552147239, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6226523, Length=248, Percent_Identity=32.6612903225806, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 74514; Mature: 74514

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCC
>Mature Secondary Structure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HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8200541; 12597275 [H]