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The map label for this gene is rfbC [C]

Identifier: 146341725

GI number: 146341725

Start: 5035227

End: 5035769

Strand: Reverse

Name: rfbC [C]

Synonym: BRADO4830

Alternate gene names: 146341725

Gene position: 5035769-5035227 (Counterclockwise)

Preceding gene: 146341726

Following gene: 146341724

Centisome position: 67.53

GC content: 63.9

Gene sequence:

>543_bases
ATGAAGTTTGTCCAGCTGGGACGATCGGATGCGCGGCTGATCGAGCTCACGGTGCGCGGCGATGAGCGCGGCAGCTTCAC
GCGGACTTGGTGTGCGAAGACCTTTGCCGCCGAGGAGATCGACTTCCAGCCCGTTCAGGGCAACAGCTCGGTGACGCGCC
ATCGCGGCACCGTGCGTGGCATGCATTTTCAGCGCGCGCCGAAGGCCGATGCCAAGATCGTCCGGTGCACCGCGGGCCTG
ATCCATGACGTCATCGTCGATGTCAGGCCGACATCAGCGACGCGCGGCGAGGTCTATGCCTGCGAGCTTGGGCCATCGAC
GGGCCGGATGCTCTACATTCCCGCCGGATTTGCCCACGGCTTCCAGACCCTGACGGATGATGTGACCGTCGAGTACCTGA
TGGGCATCGACTATGTCGAGGAGCTTTCCGACGGCTTCCGGCACAACGATCCCCTGATCAGCATCAAATGGCCGGGGCCG
GTGACGGTGTTGTCCGCGAAAGATGCTGCGTGGCCGTTGCTCGCCGAGCGGCCCTTGTGGTGA

Upstream 100 bases:

>100_bases
CCATCGAGGAGTGATCGACGAGATCCGTGGGGCCCGCCCTGCATCAGCGGGCGGCTCTCGGATACCGCCGCGTTGGCATC
TCGGAGCGAAAGAAATTGCG

Downstream 100 bases:

>100_bases
GCGCGCCGAAGGACCGAAATCGGGTCAGGCCGTCCTTGAAGAGGTGTGCGTCATGCTGGACATGGTGAAATCGCCCGCCG
CGGAGCGAACGCCGGCCATC

Product: putative dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKFVQLGRSDARLIELTVRGDERGSFTRTWCAKTFAAEEIDFQPVQGNSSVTRHRGTVRGMHFQRAPKADAKIVRCTAGL
IHDVIVDVRPTSATRGEVYACELGPSTGRMLYIPAGFAHGFQTLTDDVTVEYLMGIDYVEELSDGFRHNDPLISIKWPGP
VTVLSAKDAAWPLLAERPLW

Sequences:

>Translated_180_residues
MKFVQLGRSDARLIELTVRGDERGSFTRTWCAKTFAAEEIDFQPVQGNSSVTRHRGTVRGMHFQRAPKADAKIVRCTAGL
IHDVIVDVRPTSATRGEVYACELGPSTGRMLYIPAGFAHGFQTLTDDVTVEYLMGIDYVEELSDGFRHNDPLISIKWPGP
VTVLSAKDAAWPLLAERPLW
>Mature_180_residues
MKFVQLGRSDARLIELTVRGDERGSFTRTWCAKTFAAEEIDFQPVQGNSSVTRHRGTVRGMHFQRAPKADAKIVRCTAGL
IHDVIVDVRPTSATRGEVYACELGPSTGRMLYIPAGFAHGFQTLTDDVTVEYLMGIDYVEELSDGFRHNDPLISIKWPGP
VTVLSAKDAAWPLLAERPLW

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=172, Percent_Identity=37.2093023255814, Blast_Score=99, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17550412, Length=164, Percent_Identity=33.5365853658537, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20019; Mature: 20019

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVQLGRSDARLIELTVRGDERGSFTRTWCAKTFAAEEIDFQPVQGNSSVTRHRGTVRG
CCCEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCCC
MHFQRAPKADAKIVRCTAGLIHDVIVDVRPTSATRGEVYACELGPSTGRMLYIPAGFAHG
CEECCCCCCCCEEEEHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCCEEEEEECCHHHH
FQTLTDDVTVEYLMGIDYVEELSDGFRHNDPLISIKWPGPVTVLSAKDAAWPLLAERPLW
HHHHCCHHEEEEHHCCHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKFVQLGRSDARLIELTVRGDERGSFTRTWCAKTFAAEEIDFQPVQGNSSVTRHRGTVRG
CCCEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCCC
MHFQRAPKADAKIVRCTAGLIHDVIVDVRPTSATRGEVYACELGPSTGRMLYIPAGFAHG
CEECCCCCCCCEEEEHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCCEEEEEECCHHHH
FQTLTDDVTVEYLMGIDYVEELSDGFRHNDPLISIKWPGPVTVLSAKDAAWPLLAERPLW
HHHHCCHHEEEEHHCCHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]