Click here to switch to the map view.

The map label for this gene is mcpE [H]

Identifier: 146341424

GI number: 146341424

Start: 4715944

End: 4717296

Strand: Direct

Name: mcpE [H]

Synonym: BRADO4514

Alternate gene names: 146341424

Gene position: 4715944-4717296 (Clockwise)

Preceding gene: 146341423

Following gene: 146341431

Centisome position: 63.25

GC content: 67.85

Gene sequence:

>1353_bases
ATGACCGATCTGACGACACTGCAATCCCGCCTCGACTTCATCGGCATCGACAACGCGACCCGGGAGCATCTGCGCGAGCT
GCGGCCGCTGATCGGCAAGGTGCTGCCGGGCCTGCTCGACAAGTTCTACGCCCATGTCGGCAAGGTGCCGTCGCTGGCGA
AGATGTTCTCCAGCCAGACGGCGATGCGGCACGCCCACAAGGCCCAGCTCGACCATTGGATGTCGCTGGCGACCGCCAAG
TTCGACGACGCCTATGTGAAGTCCGTGACGCGCATCGGCCAGGCCCACAACCGGATGGGGCTGGAGCCGCGCTGGTACAT
CGCCGGCTATTCGCTGATCGTCACCGGCCTGCAGCAGGCGATCGAGACCGAGCTGTTAGACGGCTGGTTCGGCGGCCAGG
CCGCGCGCGAGAAGAAGGCGGCGCTGCAGGCCGCGATCACCAAGGCGGCGATGATCGACATGGATCTCGCGCTGTCGGTC
TATCTCGACGCCGCCAAGACCGAACAGCATGCCGCCATGCGGCGCATGGCCGACGAGTTCGAATCCACGGTCGGCCAGAT
CATCAACAAGGTCCATGCCGACGCGCGCACGCTGGAGGTCTCGGCCAACACGCTGAGCAAGACCGCCGAGCAGACCCAGC
AGCTGTCGACCAGCGCGGCCGCGGCCTCCGGCCAGGTTTCGGCCACGGTCCAGTCGGTGGCATCGGCCGCTGGCGAGATG
ACGTCCTCCGTGCACGAGATCGGCCGCCGCGTCACGGAATCGACCAGCATCGCCAAGGAGGCCGTGCGGCAGATCGAGCA
GACCGATGTCGGCATCAGCGAGCTGTCGCGCACCGCCGAGCGCATCGGCGACGTGCTCAAGCTGATCACCTCGATCGCCG
CACAGACGAATCTGCTCGCGCTCAACGCCACGATCGAAGCGGCGCGCGCCGGCGACGCCGGCCGCGGCTTCGCGGTGGTC
GCCTCCGAGGTCAAGGCGCTGGCCTCGCAAACCGCGAAGGCCACCGAGGAAATCGGTCAGCAGATCGAGGGCATCCAGAA
CGCGACGCAGTCCTCCGTCGCCTCGATCAAGCAGATCGGCGGCACCATCCAGCAGATCTCGGAGATCGCGGCCGGAATCG
CCGCGGCCGTCGAGCAGCAGGGCGCGGCCACGAGTCAGATCTCGCGCAACGTCCAGGACGTCGCCGGCGGCACGGCGCGC
GTGGTCGGCAATATCGGCGACGTCAGCAAGGGCGCAGACGCCACCGGCGCCGCGTCCTCACAGGTCCTCACCTCGGCCCA
CTCGCTGTCGCGCGAGAGCGACCGGCTGAAGGACGAGCTGGAGAAATTCCTGCGCAAGGTCCGCGCCGCCTGA

Upstream 100 bases:

>100_bases
GCCGTAAGGAACCATCAACCAAACCCGTGCAATTCTAGGGGTAGCGAGGCACTCCGCAGCGCGGCCTCTCCCTTGCGTAC
GGATGACGGGCGGACCAGCG

Downstream 100 bases:

>100_bases
ACGGCGCGACGAACTACATGCCGTGGCTCTGGAACACCGCCGAGCAGCGCTTGCTGAGCTTCTGCCGGTTCTGCGTCAGG
CAGTTCTGGACCGCGAAGTC

Product: putative chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTDLTTLQSRLDFIGIDNATREHLRELRPLIGKVLPGLLDKFYAHVGKVPSLAKMFSSQTAMRHAHKAQLDHWMSLATAK
FDDAYVKSVTRIGQAHNRMGLEPRWYIAGYSLIVTGLQQAIETELLDGWFGGQAAREKKAALQAAITKAAMIDMDLALSV
YLDAAKTEQHAAMRRMADEFESTVGQIINKVHADARTLEVSANTLSKTAEQTQQLSTSAAAASGQVSATVQSVASAAGEM
TSSVHEIGRRVTESTSIAKEAVRQIEQTDVGISELSRTAERIGDVLKLITSIAAQTNLLALNATIEAARAGDAGRGFAVV
ASEVKALASQTAKATEEIGQQIEGIQNATQSSVASIKQIGGTIQQISEIAAGIAAAVEQQGAATSQISRNVQDVAGGTAR
VVGNIGDVSKGADATGAASSQVLTSAHSLSRESDRLKDELEKFLRKVRAA

Sequences:

>Translated_450_residues
MTDLTTLQSRLDFIGIDNATREHLRELRPLIGKVLPGLLDKFYAHVGKVPSLAKMFSSQTAMRHAHKAQLDHWMSLATAK
FDDAYVKSVTRIGQAHNRMGLEPRWYIAGYSLIVTGLQQAIETELLDGWFGGQAAREKKAALQAAITKAAMIDMDLALSV
YLDAAKTEQHAAMRRMADEFESTVGQIINKVHADARTLEVSANTLSKTAEQTQQLSTSAAAASGQVSATVQSVASAAGEM
TSSVHEIGRRVTESTSIAKEAVRQIEQTDVGISELSRTAERIGDVLKLITSIAAQTNLLALNATIEAARAGDAGRGFAVV
ASEVKALASQTAKATEEIGQQIEGIQNATQSSVASIKQIGGTIQQISEIAAGIAAAVEQQGAATSQISRNVQDVAGGTAR
VVGNIGDVSKGADATGAASSQVLTSAHSLSRESDRLKDELEKFLRKVRAA
>Mature_449_residues
TDLTTLQSRLDFIGIDNATREHLRELRPLIGKVLPGLLDKFYAHVGKVPSLAKMFSSQTAMRHAHKAQLDHWMSLATAKF
DDAYVKSVTRIGQAHNRMGLEPRWYIAGYSLIVTGLQQAIETELLDGWFGGQAAREKKAALQAAITKAAMIDMDLALSVY
LDAAKTEQHAAMRRMADEFESTVGQIINKVHADARTLEVSANTLSKTAEQTQQLSTSAAAASGQVSATVQSVASAAGEMT
SSVHEIGRRVTESTSIAKEAVRQIEQTDVGISELSRTAERIGDVLKLITSIAAQTNLLALNATIEAARAGDAGRGFAVVA
SEVKALASQTAKATEEIGQQIEGIQNATQSSVASIKQIGGTIQQISEIAAGIAAAVEQQGAATSQISRNVQDVAGGTARV
VGNIGDVSKGADATGAASSQVLTSAHSLSRESDRLKDELEKFLRKVRAA

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=302, Percent_Identity=29.1390728476821, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788194, Length=196, Percent_Identity=32.6530612244898, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788195, Length=211, Percent_Identity=30.8056872037915, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789453, Length=227, Percent_Identity=30.8370044052863, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787690, Length=260, Percent_Identity=28.4615384615385, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR012292
- InterPro:   IPR009050 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 47688; Mature: 47557

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDLTTLQSRLDFIGIDNATREHLRELRPLIGKVLPGLLDKFYAHVGKVPSLAKMFSSQT
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AMRHAHKAQLDHWMSLATAKFDDAYVKSVTRIGQAHNRMGLEPRWYIAGYSLIVTGLQQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
IETELLDGWFGGQAAREKKAALQAAITKAAMIDMDLALSVYLDAAKTEQHAAMRRMADEF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESTVGQIINKVHADARTLEVSANTLSKTAEQTQQLSTSAAAASGQVSATVQSVASAAGEM
HHHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TSSVHEIGRRVTESTSIAKEAVRQIEQTDVGISELSRTAERIGDVLKLITSIAAQTNLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LNATIEAARAGDAGRGFAVVASEVKALASQTAKATEEIGQQIEGIQNATQSSVASIKQIG
EEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTIQQISEIAAGIAAAVEQQGAATSQISRNVQDVAGGTARVVGNIGDVSKGADATGAASS
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHH
QVLTSAHSLSRESDRLKDELEKFLRKVRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]