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The map label for this gene is rnr [H]

Identifier: 146341419

GI number: 146341419

Start: 4710072

End: 4712471

Strand: Direct

Name: rnr [H]

Synonym: BRADO4509

Alternate gene names: 146341419

Gene position: 4710072-4712471 (Clockwise)

Preceding gene: 146341418

Following gene: 146341420

Centisome position: 63.17

GC content: 67.25

Gene sequence:

>2400_bases
ATGAAACAAAAGCGCGACATCGGCTTCCCTCCGCGGGAGGCCATCGTCGCCTTCATCCGCGCCAATCCGGGCAAGATCGG
CACCAAGGACATCGCCCGCGAGTTCGGCCTGAAGAACGCCGACCGCGCAGCCCTCAAGGAGCTGCTGCGCGAGCTCATCG
CCGACGGCACCATCAAGAAGAGCGGCCGCAAGAAAATCGTCGAGCCCGCCACCCTGCCGGCGACTCTGGTCGCCGACATC
ACCGGCCGCGACAGCGACGGCGAGCTGATCGCAAAACCCGCCGAGTGGGACGAGGCCGAGCAGTCCGAGCCGCCGCGCAT
CCGTATCTACGCGTCTCGCCTCGCCAAGCCCGGCGCCACCGCCGGCGTCGGCGACCGCGCTTTGCTCCGCGTCGAACCGA
TCAACGATGCCGACGGGATCGCCTATCGCGGCCGTGTGCTGAAGGTGCTCGACCAGGCGCGCAACCGCGTGCTCGGCATC
TTCAAGAGCAACCCCAATGGCGGCGGCCGCCTGATCCCGGTCGACAAGAAGCAGGCCGGCCGCGAGCTGTCGATTGCGCC
GGGCGACACCCGCGACGCCAAGGACGGCGATCTCATCAGCGTCGACCTGTTGCGCGGCCGTGGCTACGGCTTGCCGGCGG
GCCGCGTGAAGGAGCGCTACGGCTCGGTGGCGACCGAGAAGGCGATCAGCCTGATCGCGATCCACGCCCACGAGATTCCG
ATGGACTTCTCGGCCGCGGCGATCGCGGAAGCCGAAGCCGCGCAGCCGGCGACCTTGAAGGGCCGCGAGGACTGGCGCGA
CCTGCCGCTGGTCACGATCGATCCGCCCGACGCCAAAGACCATGACGACGCCGTCCACGCCGAGCCGGATCCCGATCCGA
ACAATGCCGGCGGCTTCATTCTCCACGTCGCGATCGCCGACGTCGCCTACTACGTGCGGCCGGGCTCGGCGCTCGATCGC
GACGCGCTGATCCGCGGCAACTCGGTCTATTTCCCCGACCGCGTCGTGCCGATGCTGCCCGAGCGCATCTCCAACAATCT
GTGCTCGCTGGTGCCGGGCGAAGCGCGCGGCGCGCTCGCCGTCCGCATGGTGATGGGCGCCGACGGCCGCAAGCGCTCGC
ACTCGTTCCACCGCGTGCTGATGCGCTCGGCCGCAAAGCTCTCCTACGCGCAGGCGCAGGCCGCTGTTGACGGCAAGCCT
GACGACGTCACAGGTCCGCTGCTCGAGCCCATTCTCAAGCCGCTCTATGCCGCCTATGAGGTCGCCAAGCGCGGCCGCGA
TGCGCGCGATCCGCTCGACCTCGACCTCCCCGAGCGCAAGATCCTGCTCAAGAAGGACGGCACCGTCGACCGCGTCGTCG
TGCCCGAACGCCTCGACGCGCACCGGCTGATCGAGGAGTTCATGATCCTCGCCAACGTCGCCGCGGCTGAGGCGCTGGAG
AAGAAGGCGCTGCCGCTGATCTACCGCGTGCATGACGAGCCGACGGTCGAGAAGGTGCATGCGCTGCAGGAGTTCCTGAA
GACGCTCGACGTGCCCTTTGCAAAATCGGGCGCGCTGCGGCCGTCGCTGTTCAACCGCGTGCTCACACTGGTCGCCGGCC
AGGACTACGAGAAGCTCGTGAACGAGGTCGTGCTGCGCTCGCAGGCGCAAGCCGAGTACTCCTCCGAAAATTACGGGCAT
TTCGGCCTGAACCTGCGCCGCTACGCCCACTTCACCTCGCCGATCCGCCGCTATGCCGATCTCGTCGTGCACCGCGGCTT
GTTGCGTGCGCTGGGTCTGGGCGACGGCGCCCTGCCCGATAGCGAGACGGCGGACCATCTGGCCGAAGTTGCCGCTCAGA
TCTCGGTCACCGAGCGGCGGGCGATGAAGGCGGAACGCGAGACGGCCGACCGCTTGATCGCGCATCACCTCGCCGACCGC
GTCGGCGCCTCGTTCCAGGGCCGCATCTCCGGCGTCACCCGCGCCGGCCTCTTCATCAAGCTCGACGAGACCGGCGCTGA
CGGCCTGGTGCCGATCCGAACCCTCGGAACGGAATATTTCGATTACGACGAGACGCGCCACGCACTGATCGGCCAGCGCA
GTGGTGCCATGCATCGGCTCGGTGACGTCGTCGACGTGCGTCTGGTAGAAGCTCAACCGGTGGCCGGTGCGCTGCGGTTC
GAACTGCTGACGCAGGCCGATGTGCTGGTGTCGCGGCATCCGCGTGGCGCGGGCCCCAGGCGCAAGAATACCGTCGGGAC
GAACGCCAAAGCGGTTGCCAAGGCGATCAAGCGCGGCAAGTCCGAGGCTCGCACGAAGCATAAAGAGAAGCATAAAGAAA
AGAGCCGTAAGAAAAGCCAGAAGGCAGGGGCAAAACGCAAGCCCGGCACATCGAAGAAAGGCCAATCATGGACGCCATGA

Upstream 100 bases:

>100_bases
AAGGCGCGTGCGCCGGTTGCGAAGGCCGCCAAGACATCGGCCAAGCCCGCCACCAAGGCCACGCCCAAGAAGAGCGCCGG
CAAGGCCCGCGGATGAGAAA

Downstream 100 bases:

>100_bases
GTTCTACGCCCCGCGCATTGCCGCAAACTTTGACAAAGACTTGGACTCGCGACACCGGTCTCGCCGAAAAGCGCGACGTC
TGGACCGCCATGAAGCGCGG

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 799; Mature: 799

Protein sequence:

>799_residues
MKQKRDIGFPPREAIVAFIRANPGKIGTKDIAREFGLKNADRAALKELLRELIADGTIKKSGRKKIVEPATLPATLVADI
TGRDSDGELIAKPAEWDEAEQSEPPRIRIYASRLAKPGATAGVGDRALLRVEPINDADGIAYRGRVLKVLDQARNRVLGI
FKSNPNGGGRLIPVDKKQAGRELSIAPGDTRDAKDGDLISVDLLRGRGYGLPAGRVKERYGSVATEKAISLIAIHAHEIP
MDFSAAAIAEAEAAQPATLKGREDWRDLPLVTIDPPDAKDHDDAVHAEPDPDPNNAGGFILHVAIADVAYYVRPGSALDR
DALIRGNSVYFPDRVVPMLPERISNNLCSLVPGEARGALAVRMVMGADGRKRSHSFHRVLMRSAAKLSYAQAQAAVDGKP
DDVTGPLLEPILKPLYAAYEVAKRGRDARDPLDLDLPERKILLKKDGTVDRVVVPERLDAHRLIEEFMILANVAAAEALE
KKALPLIYRVHDEPTVEKVHALQEFLKTLDVPFAKSGALRPSLFNRVLTLVAGQDYEKLVNEVVLRSQAQAEYSSENYGH
FGLNLRRYAHFTSPIRRYADLVVHRGLLRALGLGDGALPDSETADHLAEVAAQISVTERRAMKAERETADRLIAHHLADR
VGASFQGRISGVTRAGLFIKLDETGADGLVPIRTLGTEYFDYDETRHALIGQRSGAMHRLGDVVDVRLVEAQPVAGALRF
ELLTQADVLVSRHPRGAGPRRKNTVGTNAKAVAKAIKRGKSEARTKHKEKHKEKSRKKSQKAGAKRKPGTSKKGQSWTP

Sequences:

>Translated_799_residues
MKQKRDIGFPPREAIVAFIRANPGKIGTKDIAREFGLKNADRAALKELLRELIADGTIKKSGRKKIVEPATLPATLVADI
TGRDSDGELIAKPAEWDEAEQSEPPRIRIYASRLAKPGATAGVGDRALLRVEPINDADGIAYRGRVLKVLDQARNRVLGI
FKSNPNGGGRLIPVDKKQAGRELSIAPGDTRDAKDGDLISVDLLRGRGYGLPAGRVKERYGSVATEKAISLIAIHAHEIP
MDFSAAAIAEAEAAQPATLKGREDWRDLPLVTIDPPDAKDHDDAVHAEPDPDPNNAGGFILHVAIADVAYYVRPGSALDR
DALIRGNSVYFPDRVVPMLPERISNNLCSLVPGEARGALAVRMVMGADGRKRSHSFHRVLMRSAAKLSYAQAQAAVDGKP
DDVTGPLLEPILKPLYAAYEVAKRGRDARDPLDLDLPERKILLKKDGTVDRVVVPERLDAHRLIEEFMILANVAAAEALE
KKALPLIYRVHDEPTVEKVHALQEFLKTLDVPFAKSGALRPSLFNRVLTLVAGQDYEKLVNEVVLRSQAQAEYSSENYGH
FGLNLRRYAHFTSPIRRYADLVVHRGLLRALGLGDGALPDSETADHLAEVAAQISVTERRAMKAERETADRLIAHHLADR
VGASFQGRISGVTRAGLFIKLDETGADGLVPIRTLGTEYFDYDETRHALIGQRSGAMHRLGDVVDVRLVEAQPVAGALRF
ELLTQADVLVSRHPRGAGPRRKNTVGTNAKAVAKAIKRGKSEARTKHKEKHKEKSRKKSQKAGAKRKPGTSKKGQSWTP
>Mature_799_residues
MKQKRDIGFPPREAIVAFIRANPGKIGTKDIAREFGLKNADRAALKELLRELIADGTIKKSGRKKIVEPATLPATLVADI
TGRDSDGELIAKPAEWDEAEQSEPPRIRIYASRLAKPGATAGVGDRALLRVEPINDADGIAYRGRVLKVLDQARNRVLGI
FKSNPNGGGRLIPVDKKQAGRELSIAPGDTRDAKDGDLISVDLLRGRGYGLPAGRVKERYGSVATEKAISLIAIHAHEIP
MDFSAAAIAEAEAAQPATLKGREDWRDLPLVTIDPPDAKDHDDAVHAEPDPDPNNAGGFILHVAIADVAYYVRPGSALDR
DALIRGNSVYFPDRVVPMLPERISNNLCSLVPGEARGALAVRMVMGADGRKRSHSFHRVLMRSAAKLSYAQAQAAVDGKP
DDVTGPLLEPILKPLYAAYEVAKRGRDARDPLDLDLPERKILLKKDGTVDRVVVPERLDAHRLIEEFMILANVAAAEALE
KKALPLIYRVHDEPTVEKVHALQEFLKTLDVPFAKSGALRPSLFNRVLTLVAGQDYEKLVNEVVLRSQAQAEYSSENYGH
FGLNLRRYAHFTSPIRRYADLVVHRGLLRALGLGDGALPDSETADHLAEVAAQISVTERRAMKAERETADRLIAHHLADR
VGASFQGRISGVTRAGLFIKLDETGADGLVPIRTLGTEYFDYDETRHALIGQRSGAMHRLGDVVDVRLVEAQPVAGALRF
ELLTQADVLVSRHPRGAGPRRKNTVGTNAKAVAKAIKRGKSEARTKHKEKHKEKSRKKSQKAGAKRKPGTSKKGQSWTP

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI134288890, Length=405, Percent_Identity=33.5802469135802, Blast_Score=169, Evalue=9e-42,
Organism=Homo sapiens, GI190014623, Length=555, Percent_Identity=27.2072072072072, Blast_Score=166, Evalue=9e-41,
Organism=Homo sapiens, GI190014625, Length=555, Percent_Identity=27.2072072072072, Blast_Score=166, Evalue=9e-41,
Organism=Homo sapiens, GI19115966, Length=422, Percent_Identity=30.0947867298578, Blast_Score=133, Evalue=8e-31,
Organism=Homo sapiens, GI219521928, Length=508, Percent_Identity=27.755905511811, Blast_Score=132, Evalue=9e-31,
Organism=Escherichia coli, GI87082383, Length=746, Percent_Identity=32.9758713136729, Blast_Score=349, Evalue=4e-97,
Organism=Escherichia coli, GI1787542, Length=472, Percent_Identity=31.9915254237288, Blast_Score=171, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI212645896, Length=554, Percent_Identity=28.5198555956679, Blast_Score=172, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17553506, Length=404, Percent_Identity=30.6930693069307, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324552, Length=442, Percent_Identity=30.5429864253394, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6320499, Length=391, Percent_Identity=24.2966751918159, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24649634, Length=489, Percent_Identity=28.2208588957055, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI19922976, Length=441, Percent_Identity=27.2108843537415, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24654597, Length=441, Percent_Identity=27.2108843537415, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24654592, Length=441, Percent_Identity=27.2108843537415, Blast_Score=131, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 87262; Mature: 87262

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKRDIGFPPREAIVAFIRANPGKIGTKDIAREFGLKNADRAALKELLRELIADGTIKK
CCCCCCCCCCCHHHHEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
SGRKKIVEPATLPATLVADITGRDSDGELIAKPAEWDEAEQSEPPRIRIYASRLAKPGAT
CCCCCCCCCCCCCHHHEEECCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEHHHCCCCCC
AGVGDRALLRVEPINDADGIAYRGRVLKVLDQARNRVLGIFKSNPNGGGRLIPVDKKQAG
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEECCHHHCC
RELSIAPGDTRDAKDGDLISVDLLRGRGYGLPAGRVKERYGSVATEKAISLIAIHAHEIP
CEEEECCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHCCHHHHHHHEEEEEEHHCCC
MDFSAAAIAEAEAAQPATLKGREDWRDLPLVTIDPPDAKDHDDAVHAEPDPDPNNAGGFI
CCCCHHHHHHHHCCCCCCCCCCCCHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEE
LHVAIADVAYYVRPGSALDRDALIRGNSVYFPDRVVPMLPERISNNLCSLVPGEARGALA
EEHHHHHHHHHCCCCCCCCCHHEECCCEEECCCCHHHHHHHHHCCCHHHCCCCCCCCCEE
VRMVMGADGRKRSHSFHRVLMRSAAKLSYAQAQAAVDGKPDDVTGPLLEPILKPLYAAYE
EEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
VAKRGRDARDPLDLDLPERKILLKKDGTVDRVVVPERLDAHRLIEEFMILANVAAAEALE
HHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
KKALPLIYRVHDEPTVEKVHALQEFLKTLDVPFAKSGALRPSLFNRVLTLVAGQDYEKLV
HCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
NEVVLRSQAQAEYSSENYGHFGLNLRRYAHFTSPIRRYADLVVHRGLLRALGLGDGALPD
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SETADHLAEVAAQISVTERRAMKAERETADRLIAHHLADRVGASFQGRISGVTRAGLFIK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEECCEEEE
LDETGADGLVPIRTLGTEYFDYDETRHALIGQRSGAMHRLGDVVDVRLVEAQPVAGALRF
EECCCCCCCEEHHHHCCHHCCCCHHHHHHHCCCCCCHHHHCCHHEEEEEECCCCHHHHHH
ELLTQADVLVSRHPRGAGPRRKNTVGTNAKAVAKAIKRGKSEARTKHKEKHKEKSRKKSQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
KAGAKRKPGTSKKGQSWTP
HCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQKRDIGFPPREAIVAFIRANPGKIGTKDIAREFGLKNADRAALKELLRELIADGTIKK
CCCCCCCCCCCHHHHEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
SGRKKIVEPATLPATLVADITGRDSDGELIAKPAEWDEAEQSEPPRIRIYASRLAKPGAT
CCCCCCCCCCCCCHHHEEECCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEHHHCCCCCC
AGVGDRALLRVEPINDADGIAYRGRVLKVLDQARNRVLGIFKSNPNGGGRLIPVDKKQAG
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEECCHHHCC
RELSIAPGDTRDAKDGDLISVDLLRGRGYGLPAGRVKERYGSVATEKAISLIAIHAHEIP
CEEEECCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHCCHHHHHHHEEEEEEHHCCC
MDFSAAAIAEAEAAQPATLKGREDWRDLPLVTIDPPDAKDHDDAVHAEPDPDPNNAGGFI
CCCCHHHHHHHHCCCCCCCCCCCCHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEE
LHVAIADVAYYVRPGSALDRDALIRGNSVYFPDRVVPMLPERISNNLCSLVPGEARGALA
EEHHHHHHHHHCCCCCCCCCHHEECCCEEECCCCHHHHHHHHHCCCHHHCCCCCCCCCEE
VRMVMGADGRKRSHSFHRVLMRSAAKLSYAQAQAAVDGKPDDVTGPLLEPILKPLYAAYE
EEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
VAKRGRDARDPLDLDLPERKILLKKDGTVDRVVVPERLDAHRLIEEFMILANVAAAEALE
HHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
KKALPLIYRVHDEPTVEKVHALQEFLKTLDVPFAKSGALRPSLFNRVLTLVAGQDYEKLV
HCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
NEVVLRSQAQAEYSSENYGHFGLNLRRYAHFTSPIRRYADLVVHRGLLRALGLGDGALPD
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SETADHLAEVAAQISVTERRAMKAERETADRLIAHHLADRVGASFQGRISGVTRAGLFIK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEECCEEEE
LDETGADGLVPIRTLGTEYFDYDETRHALIGQRSGAMHRLGDVVDVRLVEAQPVAGALRF
EECCCCCCCEEHHHHCCHHCCCCHHHHHHHCCCCCCHHHHCCHHEEEEEECCCCHHHHHH
ELLTQADVLVSRHPRGAGPRRKNTVGTNAKAVAKAIKRGKSEARTKHKEKHKEKSRKKSQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
KAGAKRKPGTSKKGQSWTP
HCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]