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The map label for this gene is adh [H]

Identifier: 146341276

GI number: 146341276

Start: 4543684

End: 4544727

Strand: Reverse

Name: adh [H]

Synonym: BRADO4353

Alternate gene names: 146341276

Gene position: 4544727-4543684 (Counterclockwise)

Preceding gene: 146341279

Following gene: 146341275

Centisome position: 60.95

GC content: 63.98

Gene sequence:

>1044_bases
ATGAAGGCCGCGGTGCTCCATGCGTTCGATGAGAAGCTGACCTCGAGAGAGTTCGTCAGATACGAGGAGGTTCCCGACCC
GAAGATCTCGCGTCCGATGGACGTGATCGTGCGCATCGGTGGCGCCGGCGTCTGCCGTACCGATCTTCACATCGTCGAGG
GAATCTGGCGCAGCAAGGTCGACGTCAAGCTCCCCTACATCATGGGTCATGAAAACGCGGGCTGGGTCGAGGCGGTCGGT
CCCGGTGTCGAGGGCGTCAAGGTCGGTGACAGCGTCATCTGTCACCCGCTGGTGACCAGCGGCCATTGTCTGGCATGCAG
GCGCGGCAACGACATGCATGCGCTCGACAGTAGCTTTCCCGGCATCAATGCCAATGGCGGCTACGCGCAATATCTGCTGA
CCGGACAGCGCTCGTTGATCAAGCTGCCGAAGTCGCTGGCGCCAAAGGACGTCGCTCCCTACACGGACGCGGGATTGACC
GCCTACCGCGCCGCCAAGAAAGCGTCGCGCCACCTGCTGCCTGGCGAATATGTCGTGGTGATCGGGGCAGGCGGTCTCGG
CCATATCGGCATCCAGGTTCTCGCGGCGCTATGCGCGGCGGAGATCGTCGTCGTCGACCGCTCCGAGAAATCGCTGGAGC
TCGCCAAGACCTGTGGCGCGCATCACCTGGTCAAGGCTGAGGGCGGCGAGGTCGAGGCGGTGCTGGCGCTGACCGGCGGG
CGTGGGGCTGAGGCGGTGATCGACTTCGTCGGCGAGGGCGATGCGGTGGCCAAGGGACTGGCGATGACCGCCAATGGCGG
CACCTACTACATCGTCGGTTACGGCGGCAAGATCGAGCTGCCGACCATCGACATGATCACGACCGAGAAGAGCATCGTCG
GCAACCTGGTCGGCACCTATGCCGAGCTGGTCGAATTGATGGCGCTCGCGGACCGCGGTCTCGTGACGCTGCACACCAGG
GAATACCGGCTCAGCGAGGCCAATGATGCGCTCCACGATCTGCATCATGGGCGCATCCACGGACGTGCCGTGCTGATTCC
TTGA

Upstream 100 bases:

>100_bases
ATTATCAATCTGTTAGCTCCCTGGCATAGCTCTTGCTCAACCTTGGACAACGACGGCTGCGACACGTTGACGTCGAAACA
AAAAAATCCGGGGAGACGAC

Downstream 100 bases:

>100_bases
AGGCAGGCGCGGCCAATGCTCGATGTCGATCTCAATCGTCGAACGAGAGTGATGCGGGTGACCAAGTCCGGCGAAGGCGG
GCCAAAGATCACGGCCGAGC

Product: putative alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKAAVLHAFDEKLTSREFVRYEEVPDPKISRPMDVIVRIGGAGVCRTDLHIVEGIWRSKVDVKLPYIMGHENAGWVEAVG
PGVEGVKVGDSVICHPLVTSGHCLACRRGNDMHALDSSFPGINANGGYAQYLLTGQRSLIKLPKSLAPKDVAPYTDAGLT
AYRAAKKASRHLLPGEYVVVIGAGGLGHIGIQVLAALCAAEIVVVDRSEKSLELAKTCGAHHLVKAEGGEVEAVLALTGG
RGAEAVIDFVGEGDAVAKGLAMTANGGTYYIVGYGGKIELPTIDMITTEKSIVGNLVGTYAELVELMALADRGLVTLHTR
EYRLSEANDALHDLHHGRIHGRAVLIP

Sequences:

>Translated_347_residues
MKAAVLHAFDEKLTSREFVRYEEVPDPKISRPMDVIVRIGGAGVCRTDLHIVEGIWRSKVDVKLPYIMGHENAGWVEAVG
PGVEGVKVGDSVICHPLVTSGHCLACRRGNDMHALDSSFPGINANGGYAQYLLTGQRSLIKLPKSLAPKDVAPYTDAGLT
AYRAAKKASRHLLPGEYVVVIGAGGLGHIGIQVLAALCAAEIVVVDRSEKSLELAKTCGAHHLVKAEGGEVEAVLALTGG
RGAEAVIDFVGEGDAVAKGLAMTANGGTYYIVGYGGKIELPTIDMITTEKSIVGNLVGTYAELVELMALADRGLVTLHTR
EYRLSEANDALHDLHHGRIHGRAVLIP
>Mature_347_residues
MKAAVLHAFDEKLTSREFVRYEEVPDPKISRPMDVIVRIGGAGVCRTDLHIVEGIWRSKVDVKLPYIMGHENAGWVEAVG
PGVEGVKVGDSVICHPLVTSGHCLACRRGNDMHALDSSFPGINANGGYAQYLLTGQRSLIKLPKSLAPKDVAPYTDAGLT
AYRAAKKASRHLLPGEYVVVIGAGGLGHIGIQVLAALCAAEIVVVDRSEKSLELAKTCGAHHLVKAEGGEVEAVLALTGG
RGAEAVIDFVGEGDAVAKGLAMTANGGTYYIVGYGGKIELPTIDMITTEKSIVGNLVGTYAELVELMALADRGLVTLHTR
EYRLSEANDALHDLHHGRIHGRAVLIP

Specific function: Converts Galactitol 1-Phosphate To Tagatose 6-Phosphate. [C]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI262073058, Length=306, Percent_Identity=29.0849673202614, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI71743840, Length=306, Percent_Identity=29.0849673202614, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI156627571, Length=326, Percent_Identity=25.7668711656442, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI4501933, Length=302, Percent_Identity=28.1456953642384, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI4501929, Length=370, Percent_Identity=25.6756756756757, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI34577061, Length=372, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI194239674, Length=323, Percent_Identity=26.9349845201238, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI13236495, Length=323, Percent_Identity=26.9349845201238, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI156523966, Length=355, Percent_Identity=23.943661971831, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4501939, Length=347, Percent_Identity=23.9193083573487, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1788407, Length=205, Percent_Identity=32.1951219512195, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790045, Length=233, Percent_Identity=30.9012875536481, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082401, Length=324, Percent_Identity=29.0123456790123, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87081918, Length=319, Percent_Identity=28.5266457680251, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082125, Length=325, Percent_Identity=27.6923076923077, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787863, Length=204, Percent_Identity=32.3529411764706, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788073, Length=255, Percent_Identity=30.1960784313725, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI226510992, Length=301, Percent_Identity=25.9136212624585, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788075, Length=342, Percent_Identity=28.0701754385965, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790718, Length=305, Percent_Identity=26.8852459016393, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1786825, Length=261, Percent_Identity=31.0344827586207, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786518, Length=331, Percent_Identity=28.7009063444109, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=340, Percent_Identity=27.0588235294118, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562878, Length=329, Percent_Identity=24.9240121580547, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71988145, Length=335, Percent_Identity=28.0597014925373, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562584, Length=333, Percent_Identity=27.6276276276276, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562582, Length=336, Percent_Identity=26.7857142857143, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=335, Percent_Identity=31.044776119403, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323961, Length=353, Percent_Identity=28.8951841359773, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319621, Length=353, Percent_Identity=28.8951841359773, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323729, Length=335, Percent_Identity=28.0597014925373, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323099, Length=335, Percent_Identity=28.0597014925373, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319258, Length=322, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6319955, Length=331, Percent_Identity=27.190332326284, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322619, Length=331, Percent_Identity=27.190332326284, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319257, Length=323, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323980, Length=210, Percent_Identity=31.9047619047619, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320033, Length=349, Percent_Identity=26.3610315186246, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17137530, Length=342, Percent_Identity=26.9005847953216, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17737897, Length=342, Percent_Identity=26.0233918128655, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36805; Mature: 36805

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVLHAFDEKLTSREFVRYEEVPDPKISRPMDVIVRIGGAGVCRTDLHIVEGIWRSKV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHCCC
DVKLPYIMGHENAGWVEAVGPGVEGVKVGDSVICHPLVTSGHCLACRRGNDMHALDSSFP
EEEECEEEECCCCCEEEECCCCCCCEECCCCEEEEEEECCCCEEEEECCCCCCHHHCCCC
GINANGGYAQYLLTGQRSLIKLPKSLAPKDVAPYTDAGLTAYRAAKKASRHLLPGEYVVV
CCCCCCCEEEEEEECCHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEE
IGAGGLGHIGIQVLAALCAAEIVVVDRSEKSLELAKTCGAHHLVKAEGGEVEAVLALTGG
EECCCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHCCCCEEEECCCCCEEEEEEEECC
RGAEAVIDFVGEGDAVAKGLAMTANGGTYYIVGYGGKIELPTIDMITTEKSIVGNLVGTY
CCHHHHHEECCCCCHHHCCEEEEECCCEEEEEEECCEEECCEEEEEECCHHHHHHHHHHH
AELVELMALADRGLVTLHTREYRLSEANDALHDLHHGRIHGRAVLIP
HHHHHHHHHHCCCEEEEEECCEECCHHHHHHHHHHCCEECCEEEEEC
>Mature Secondary Structure
MKAAVLHAFDEKLTSREFVRYEEVPDPKISRPMDVIVRIGGAGVCRTDLHIVEGIWRSKV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHCCC
DVKLPYIMGHENAGWVEAVGPGVEGVKVGDSVICHPLVTSGHCLACRRGNDMHALDSSFP
EEEECEEEECCCCCEEEECCCCCCCEECCCCEEEEEEECCCCEEEEECCCCCCHHHCCCC
GINANGGYAQYLLTGQRSLIKLPKSLAPKDVAPYTDAGLTAYRAAKKASRHLLPGEYVVV
CCCCCCCEEEEEEECCHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEE
IGAGGLGHIGIQVLAALCAAEIVVVDRSEKSLELAKTCGAHHLVKAEGGEVEAVLALTGG
EECCCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHCCCCEEEECCCCCEEEEEEEECC
RGAEAVIDFVGEGDAVAKGLAMTANGGTYYIVGYGGKIELPTIDMITTEKSIVGNLVGTY
CCHHHHHEECCCCCHHHCCEEEEECCCEEEEEEECCEEECCEEEEEECCHHHHHHHHHHH
AELVELMALADRGLVTLHTREYRLSEANDALHDLHHGRIHGRAVLIP
HHHHHHHHHHCCCEEEEEECCEECCHHHHHHHHHHCCEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA