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The map label for this gene is clpX [H]

Identifier: 146341126

GI number: 146341126

Start: 4397378

End: 4398652

Strand: Reverse

Name: clpX [H]

Synonym: BRADO4197

Alternate gene names: 146341126

Gene position: 4398652-4397378 (Counterclockwise)

Preceding gene: 146341127

Following gene: 146341125

Centisome position: 58.99

GC content: 62.59

Gene sequence:

>1275_bases
ATGAGTAAGGTCGGAAACGGCGACGCGAAGAATACGCTTTATTGCTCGTTCTGCGGCAAGAGCCAGCACGAAGTCCGCAA
ACTGATCGCAGGTCCAACCGTCTTCATCTGCGACGAGTGCGTCGAACTCTGCATGGATATCATCCGCGAGGAGAACAAGT
CCTCGCTGGTCAAGTCGCGCGACGGCATTCCGACGCCGAAGGAAATCTGCAAGGTCCTCGACGATTACGTGATCGGCCAG
AACCATGCGAAGAAGGTGCTCTCGGTCGCCGTTCACAACCACTACAAGCGGCTCAATCACCAGACCAAGCACTCGGACGT
CGAGCTCGCGAAGTCGAACATCCTGCTGATCGGTCCGACCGGTTCGGGCAAGACGCTGCTCGCGCAGACGCTCGCCCGCA
TCCTCGACGTGCCGTTCACGATGGCCGACGCCACGACCCTGACCGAGGCCGGCTATGTCGGTGAGGACGTCGAGAACATC
ATCCTGAAGCTGCTGCAGGCGGCCGACTACAATGTCGAGCGCGCGCAGCGTGGCATTGTCTACATCGACGAGATCGACAA
GATCAGTCGGAAGTCCGACAATCCGTCGATCACGCGCGACGTCTCGGGCGAGGGCGTGCAGCAGGCGCTGCTGAAGATCA
TGGAAGGCACGGTTGCGTCGGTTCCGCCGCAGGGCGGCCGCAAGCATCCGCAGCAGGAGTTCCTGCAGGTCGACACCACC
AACATCCTGTTCATCTGCGGTGGTGCGTTCTCCGGCCTCGAGAAGATCATCTCGGCGCGCGGCCGGTCGACCTCGATCGG
CTTCGCCGCCCAAGTGCTGGCGCCGGAAGACCGCCGCACCGGCGAGATCTTCCGTCACGTCGAGCCTGAGGATCTGCTCA
AGTACGGCCTGATCCCCGAGTTCGTCGGCCGTCTGCCGGTCGTGGCGACACTCGAGGACCTCGACGAGAACTCGCTGAAG
AAGATCCTCACCGAGCCGAAGAACGCGTTGGTGAAGCAGTATCAGCGCCTGTTCGAGATGGAGAACATCGAGCTCACCTT
CGCCGACGAGGCGCTGGGTGCGGTGTCGCGCAAGGCCATCGAGCGCAAGACCGGTGCCCGTGGTCTGCGGTCGATCCTCG
AGAGCATCCTGCTCGAGACGATGTTCGACCTGCCGGGTCTCGAAGGCGTCGAGGAAGTGGTCATCTCGCGCGAGGTGGTC
GAAGGCACGGCCCGTCCGCTCTACATCTACGCCGATCGCTCCGATCGCGCGGTGGAAAGCAGCGCCAGCGCGTGA

Upstream 100 bases:

>100_bases
TTAATTTTGGTACGAATTTTGCTCTTTCATCAATTCGGTCCGGCCCGAGCCGGGTCGGAACGAACGAGCGGACAAGAGCG
AACCGCGGACGGAGATAGGA

Downstream 100 bases:

>100_bases
TCCGCGCTGGCACGATCGACAGACGACTCGATTTATCAGTTCAGCGACCGCTGCGGACGTTCAGTCCGCGGCGTCGCAGT
GTTTCAGTATCCCGCCGCGT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSKVGNGDAKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPKEICKVLDDYVIGQ
NHAKKVLSVAVHNHYKRLNHQTKHSDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFSGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPEFVGRLPVVATLEDLDENSLK
KILTEPKNALVKQYQRLFEMENIELTFADEALGAVSRKAIERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVV
EGTARPLYIYADRSDRAVESSASA

Sequences:

>Translated_424_residues
MSKVGNGDAKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPKEICKVLDDYVIGQ
NHAKKVLSVAVHNHYKRLNHQTKHSDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFSGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPEFVGRLPVVATLEDLDENSLK
KILTEPKNALVKQYQRLFEMENIELTFADEALGAVSRKAIERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVV
EGTARPLYIYADRSDRAVESSASA
>Mature_423_residues
SKVGNGDAKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPKEICKVLDDYVIGQN
HAKKVLSVAVHNHYKRLNHQTKHSDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFSGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPEFVGRLPVVATLEDLDENSLKK
ILTEPKNALVKQYQRLFEMENIELTFADEALGAVSRKAIERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVVE
GTARPLYIYADRSDRAVESSASA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=338, Percent_Identity=53.5502958579882, Blast_Score=336, Evalue=3e-92,
Organism=Escherichia coli, GI1786642, Length=402, Percent_Identity=72.1393034825871, Blast_Score=590, Evalue=1e-170,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=45.2830188679245, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=330, Percent_Identity=46.6666666666667, Blast_Score=285, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI71982905, Length=330, Percent_Identity=46.6666666666667, Blast_Score=285, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI71988663, Length=391, Percent_Identity=38.1074168797954, Blast_Score=254, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=40.8906882591093, Blast_Score=171, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=418, Percent_Identity=38.755980861244, Blast_Score=263, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24648289, Length=323, Percent_Identity=47.9876160990712, Blast_Score=304, Evalue=8e-83,
Organism=Drosophila melanogaster, GI24648291, Length=323, Percent_Identity=47.9876160990712, Blast_Score=304, Evalue=9e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46665; Mature: 46534

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVGNGDAKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSR
CCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHC
DGIPTPKEICKVLDDYVIGQNHAKKVLSVAVHNHYKRLNHQTKHSDVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHCCCC
NILFICGGAFSGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPE
CEEEEECCHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCHHHHHHCCCHHHHHHHCCCHH
FVGRLPVVATLEDLDENSLKKILTEPKNALVKQYQRLFEMENIELTFADEALGAVSRKAI
HHCCCCHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHH
ERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVVEGTARPLYIYADRSDRAVES
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHC
SASA
CCCC
>Mature Secondary Structure 
SKVGNGDAKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSR
CCCCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHC
DGIPTPKEICKVLDDYVIGQNHAKKVLSVAVHNHYKRLNHQTKHSDVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHCCCC
NILFICGGAFSGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPE
CEEEEECCHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCHHHHHHCCCHHHHHHHCCCHH
FVGRLPVVATLEDLDENSLKKILTEPKNALVKQYQRLFEMENIELTFADEALGAVSRKAI
HHCCCCHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHH
ERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVVEGTARPLYIYADRSDRAVES
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHC
SASA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA