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The map label for this gene is lpxA [H]

Identifier: 146341058

GI number: 146341058

Start: 4324176

End: 4324988

Strand: Reverse

Name: lpxA [H]

Synonym: BRADO4129

Alternate gene names: 146341058

Gene position: 4324988-4324176 (Counterclockwise)

Preceding gene: 146341059

Following gene: 146341057

Centisome position: 58.0

GC content: 66.42

Gene sequence:

>813_bases
ATGAGCAAGATTGATCCCACCGCCCGTGTCGAGGCCGGCGCCGTGATCGGCGAGGGCACCGTGATCGGTCCCTATTGCAT
CATCGGCCCGAACGTCGTGATCGGCGCGAACTGCAAGCTGATCAGCCACGTCCAGATCATGGGTCACACCACGATCGGCG
ACGACAATGTGATCTCGCCCTTCGTCGTGCTCGGCGGCGCCCCGCAGGACCTCAGTTATCGCGGCGAGCCGCACCGGCTC
GAGATCGGCTCCGGCTGCACCTTCCGCGAGGGCGTGACGATGAACATCGGCACCACCAAGGGCGGCGGCCTGACCAAGGT
CGGCAATGGCGGGTTCTTCATGAACAACGCCCACGTCGCCCATGATTGCGTCGTCGGCAACAACGTGATCTTCGCAACCT
CGGCGACGCTTGGCGGCCATGTGGAGGTCGGCGATGCCGTCTACATCGGCGGGCTCTCCGCCGTGCATCAGTTCACCCGG
ATCGGGCATGGCGTGATGGTCGGCGGCGTCTGCGGCGTGCGCGGTGACGTCATCCCCTATGGTCTCGTCAACGGCCAGTA
CGCCGCGCTCGAAGGCCTCAACGTGATCGGAATGAAGCGCCGCAAGTTCACCCGCGAGCGGCTCGCGACCGTTCGCGCCT
TCTATCAGAAGCTGTTCCACGGCCCCGGCGTGTTCGCCGATCGCCTCGCGGCCGTGCGCCCGATGGCCGGTGACGATCCG
GCCATCGACGAAATCCTCGCCTTTATCGAAGGCGGCCGCCACCGCGCGCTGTGTCTGCCGGAGATCGGCAGATCGGCGCC
CGCCGAGGCCTGA

Upstream 100 bases:

>100_bases
TCCACGGCGATGCTAAGGTCGACGGCGTGGTCGTCGCCGAGGCCGATGTCGGCGCGATGCTGACCGACTGACGTGCTGAA
AAAGAGTTGGTTGCGTTGAG

Downstream 100 bases:

>100_bases
TCGTCATGGGTGGGCCGGACAGCGAGACCACGGCGCCTGTCGGCCTGATTGCCGCCGGCGGCGTGCTGCCGTTCGCGGTC
GCTGACGCCATCGTTGCGCG

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSKIDPTARVEAGAVIGEGTVIGPYCIIGPNVVIGANCKLISHVQIMGHTTIGDDNVISPFVVLGGAPQDLSYRGEPHRL
EIGSGCTFREGVTMNIGTTKGGGLTKVGNGGFFMNNAHVAHDCVVGNNVIFATSATLGGHVEVGDAVYIGGLSAVHQFTR
IGHGVMVGGVCGVRGDVIPYGLVNGQYAALEGLNVIGMKRRKFTRERLATVRAFYQKLFHGPGVFADRLAAVRPMAGDDP
AIDEILAFIEGGRHRALCLPEIGRSAPAEA

Sequences:

>Translated_270_residues
MSKIDPTARVEAGAVIGEGTVIGPYCIIGPNVVIGANCKLISHVQIMGHTTIGDDNVISPFVVLGGAPQDLSYRGEPHRL
EIGSGCTFREGVTMNIGTTKGGGLTKVGNGGFFMNNAHVAHDCVVGNNVIFATSATLGGHVEVGDAVYIGGLSAVHQFTR
IGHGVMVGGVCGVRGDVIPYGLVNGQYAALEGLNVIGMKRRKFTRERLATVRAFYQKLFHGPGVFADRLAAVRPMAGDDP
AIDEILAFIEGGRHRALCLPEIGRSAPAEA
>Mature_269_residues
SKIDPTARVEAGAVIGEGTVIGPYCIIGPNVVIGANCKLISHVQIMGHTTIGDDNVISPFVVLGGAPQDLSYRGEPHRLE
IGSGCTFREGVTMNIGTTKGGGLTKVGNGGFFMNNAHVAHDCVVGNNVIFATSATLGGHVEVGDAVYIGGLSAVHQFTRI
GHGVMVGGVCGVRGDVIPYGLVNGQYAALEGLNVIGMKRRKFTRERLATVRAFYQKLFHGPGVFADRLAAVRPMAGDDPA
IDEILAFIEGGRHRALCLPEIGRSAPAEA

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=245, Percent_Identity=47.3469387755102, Blast_Score=214, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28202; Mature: 28071

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIDPTARVEAGAVIGEGTVIGPYCIIGPNVVIGANCKLISHVQIMGHTTIGDDNVISP
CCCCCCCCEEECCEEEECCEEECCEEEECCCEEEECCCEEEEEEEEEEEEECCCCCCCCC
FVVLGGAPQDLSYRGEPHRLEIGSGCTFREGVTMNIGTTKGGGLTKVGNGGFFMNNAHVA
EEEECCCCCCCCCCCCCCEEEECCCCEECCCEEEEECCCCCCCEEEECCCCEEECCCCEE
HDCVVGNNVIFATSATLGGHVEVGDAVYIGGLSAVHQFTRIGHGVMVGGVCGVRGDVIPY
EEEEECCCEEEEEECCCCCEEEECCEEEECCHHHHHHHHHHCCCEEECCEECCCCCCCEE
GLVNGQYAALEGLNVIGMKRRKFTRERLATVRAFYQKLFHGPGVFADRLAAVRPMAGDDP
EECCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCH
AIDEILAFIEGGRHRALCLPEIGRSAPAEA
HHHHHHHHHHCCCEEEEECHHCCCCCCCCC
>Mature Secondary Structure 
SKIDPTARVEAGAVIGEGTVIGPYCIIGPNVVIGANCKLISHVQIMGHTTIGDDNVISP
CCCCCCCEEECCEEEECCEEECCEEEECCCEEEECCCEEEEEEEEEEEEECCCCCCCCC
FVVLGGAPQDLSYRGEPHRLEIGSGCTFREGVTMNIGTTKGGGLTKVGNGGFFMNNAHVA
EEEECCCCCCCCCCCCCCEEEECCCCEECCCEEEEECCCCCCCEEEECCCCEEECCCCEE
HDCVVGNNVIFATSATLGGHVEVGDAVYIGGLSAVHQFTRIGHGVMVGGVCGVRGDVIPY
EEEEECCCEEEEEECCCCCEEEECCEEEECCHHHHHHHHHHCCCEEECCEECCCCCCCEE
GLVNGQYAALEGLNVIGMKRRKFTRERLATVRAFYQKLFHGPGVFADRLAAVRPMAGDDP
EECCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCH
AIDEILAFIEGGRHRALCLPEIGRSAPAEA
HHHHHHHHHHCCCEEEEECHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA