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The map label for this gene is tpiA [H]

Identifier: 146341036

GI number: 146341036

Start: 4296215

End: 4296970

Strand: Reverse

Name: tpiA [H]

Synonym: BRADO4107

Alternate gene names: 146341036

Gene position: 4296970-4296215 (Counterclockwise)

Preceding gene: 146341042

Following gene: 146341033

Centisome position: 57.63

GC content: 68.39

Gene sequence:

>756_bases
ATGACCGACCGCATCCGGCCCCTGATCGCCGGCAATTGGAAAATGAATGGCCTCAAGGCGTCGGCCGCGGAGTTCGAGGC
CATGCTCGCGGGGGCGGCCGAGGTCACCGGCAAGGCCGACCTCTTGGTATGCCCCCCGGCCACGCTGCTGGCGGCGTTTG
CCGAGAAGACGCGCGGCGGCAAGGCGGTCGCGGTCGGGGCGCAGGATTGCCACGCCAAGGCGTCGGGCGCCCATACGGGC
GACATCTCGGCCGAGATGCTGGCGGATGCCGGGGCCAGCGCCGTCATCGTGGGCCATTCGGAGCGGCGGGCCGACCATGG
CGAGAGCGATGTCGTCGTGCACCAGAAGGCCGAGGCGGCGTGGCGCGCCGGGCTGGTCGCGATCGTCTGCGTCGGCGAGA
CCCAGCAGCAGCGCGACGCCGGGCTGACCCTGGAGATCTTGCGCGGGCAGCTCACCCTCAGCCTGCCGGAGGGTTCGCGG
GCCGACAATCTGATCGTGGCCTATGAGCCGGTCTGGGCGATCGGCACCGGGCTGACGCCGACCGCCGGGGATGTCGAGCA
GATTCATTCCTTTATCCGGCAATTGCTGATCGTTCGGTTCAAGGAGCAGGGGGCGCGGATGCGGATCCTCTATGGTGGCT
CGGTCAAGCCGTCCAATGCGGCCGAGCTGATGGCGGTGGCCAACGTCAATGGTGCGCTGGTCGGCGGCGCGAGCCTGAAA
GCAGCAGACTTTCTCGCAATTGCGAAAGGCTGTTGA

Upstream 100 bases:

>100_bases
TGGGACGGATTGAAGCGGTGGGAAGACGGCTCGCGCTCTGGTACTCCTGCAGGGGCTCTGCTAGCCGATTTCCTGTCGTA
ACATTTGCTGGAATCCTGCC

Downstream 100 bases:

>100_bases
GAGCCAATGTGAGTGGAGCAGACGGTGCACCTCACGCGGCTGCTCCAATCCGCTTCCAATAAATCTTCGTGCCGGTGAGG
CCGCCATGCGGCTTGAAGGC

Product: triosephosphate isomerase (TIM) (Triose-phosphate isomerase)

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTDRIRPLIAGNWKMNGLKASAAEFEAMLAGAAEVTGKADLLVCPPATLLAAFAEKTRGGKAVAVGAQDCHAKASGAHTG
DISAEMLADAGASAVIVGHSERRADHGESDVVVHQKAEAAWRAGLVAIVCVGETQQQRDAGLTLEILRGQLTLSLPEGSR
ADNLIVAYEPVWAIGTGLTPTAGDVEQIHSFIRQLLIVRFKEQGARMRILYGGSVKPSNAAELMAVANVNGALVGGASLK
AADFLAIAKGC

Sequences:

>Translated_251_residues
MTDRIRPLIAGNWKMNGLKASAAEFEAMLAGAAEVTGKADLLVCPPATLLAAFAEKTRGGKAVAVGAQDCHAKASGAHTG
DISAEMLADAGASAVIVGHSERRADHGESDVVVHQKAEAAWRAGLVAIVCVGETQQQRDAGLTLEILRGQLTLSLPEGSR
ADNLIVAYEPVWAIGTGLTPTAGDVEQIHSFIRQLLIVRFKEQGARMRILYGGSVKPSNAAELMAVANVNGALVGGASLK
AADFLAIAKGC
>Mature_250_residues
TDRIRPLIAGNWKMNGLKASAAEFEAMLAGAAEVTGKADLLVCPPATLLAAFAEKTRGGKAVAVGAQDCHAKASGAHTGD
ISAEMLADAGASAVIVGHSERRADHGESDVVVHQKAEAAWRAGLVAIVCVGETQQQRDAGLTLEILRGQLTLSLPEGSRA
DNLIVAYEPVWAIGTGLTPTAGDVEQIHSFIRQLLIVRFKEQGARMRILYGGSVKPSNAAELMAVANVNGALVGGASLKA
ADFLAIAKGC

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=241, Percent_Identity=41.0788381742739, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI226529917, Length=241, Percent_Identity=41.0788381742739, Blast_Score=161, Evalue=4e-40,
Organism=Escherichia coli, GI1790353, Length=247, Percent_Identity=40.8906882591093, Blast_Score=166, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17536593, Length=241, Percent_Identity=42.3236514522822, Blast_Score=177, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6320255, Length=234, Percent_Identity=43.1623931623932, Blast_Score=180, Evalue=2e-46,
Organism=Drosophila melanogaster, GI28572004, Length=240, Percent_Identity=43.75, Blast_Score=177, Evalue=7e-45,
Organism=Drosophila melanogaster, GI28572008, Length=240, Percent_Identity=43.75, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI28572006, Length=240, Percent_Identity=43.75, Blast_Score=177, Evalue=8e-45,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 25959; Mature: 25828

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRIRPLIAGNWKMNGLKASAAEFEAMLAGAAEVTGKADLLVCPPATLLAAFAEKTRGG
CCCCCCEEEECCEEECCEECHHHHHHHHHHCHHHCCCCCCEEEECHHHHHHHHHHHCCCC
KAVAVGAQDCHAKASGAHTGDISAEMLADAGASAVIVGHSERRADHGESDVVVHQKAEAA
CEEEECCHHHCCCCCCCCCCCCHHHHHHCCCCCEEEEECCHHCCCCCCCCEEEEECHHHH
WRAGLVAIVCVGETQQQRDAGLTLEILRGQLTLSLPEGSRADNLIVAYEPVWAIGTGLTP
HHCCEEEEEEECCCHHHHHCCCEEEEEECEEEEECCCCCCCCCEEEEECCCEEECCCCCC
TAGDVEQIHSFIRQLLIVRFKEQGARMRILYGGSVKPSNAAELMAVANVNGALVGGASLK
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHEEEEEECCCCEEEECCCCC
AADFLAIAKGC
HHHHEEEECCC
>Mature Secondary Structure 
TDRIRPLIAGNWKMNGLKASAAEFEAMLAGAAEVTGKADLLVCPPATLLAAFAEKTRGG
CCCCCEEEECCEEECCEECHHHHHHHHHHCHHHCCCCCCEEEECHHHHHHHHHHHCCCC
KAVAVGAQDCHAKASGAHTGDISAEMLADAGASAVIVGHSERRADHGESDVVVHQKAEAA
CEEEECCHHHCCCCCCCCCCCCHHHHHHCCCCCEEEEECCHHCCCCCCCCEEEEECHHHH
WRAGLVAIVCVGETQQQRDAGLTLEILRGQLTLSLPEGSRADNLIVAYEPVWAIGTGLTP
HHCCEEEEEEECCCHHHHHCCCEEEEEECEEEEECCCCCCCCCEEEEECCCEEECCCCCC
TAGDVEQIHSFIRQLLIVRFKEQGARMRILYGGSVKPSNAAELMAVANVNGALVGGASLK
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHEEEEEECCCCEEEECCCCC
AADFLAIAKGC
HHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA