Click here to switch to the map view.

The map label for this gene is livH [H]

Identifier: 146341004

GI number: 146341004

Start: 4263287

End: 4264153

Strand: Reverse

Name: livH [H]

Synonym: BRADO4075

Alternate gene names: 146341004

Gene position: 4264153-4263287 (Counterclockwise)

Preceding gene: 146341005

Following gene: 146341003

Centisome position: 57.19

GC content: 63.55

Gene sequence:

>867_bases
ATGGCGATCTACGTCATTCTCGCGCTCGACGTTCTCAACGGAATCTCCTCGCTGTTCCTGCTGTGCCTGGGACTGGCGAT
CATCTTCGGCATGATGAAGATCATCAACCTCGCCCATGGCGAGTTCATCATGCTCGGAGCCTATGCGACGGTGATCTCGG
CCAATGCCGGGGTGAACATCTGGATCGCGATGCTGATCATCGCGCCCCTGTTCGTCGGCATCGTCGGTCTCGTTATCGAA
CGCTGCCTGATCCGCTTCCTGTACGGCCGCCTGGTCGATTCGATGCTCGCGACCTGGGGCCTGAGCCTCCTCATCATCGG
CATCATCACCACGATCTACGGCAACACCCAGCAGGGCGTGCCGACACCGCTCGGCGGCTTCTCGATAGGGTCATACCAAT
CGAGTTACTATACGCTGTTCCTCGCCCTGATGGCGGCGGTCATGATGGCGATCATCTACGGCGTGATGCGCTACACCCGC
TTCGGCCTGGTCGCCCGCGCCACGATGCAGAACCCGGCGATGGCCGCCACGCTCGGTGTCAACCCGGCCCGCGTCTACAT
GAGCACCTTCGCGCTCGGTGCGGCGGTCACGGGCCTCGCCGGCGGCCTGCTGGCGCCAGTGTCGGGCATCACCCCCGTGA
TGGGCGGCGCCTATGTCGCCAAGGCGTTCATGACGGTGGTCGGCGGCGGCGCAGCGATCCTCTCGGGTACGCTGTCGGCA
GCGAGCCTGTTCGGCTCGGTCAATCAGGTCGGCGCCTATTTCACCACGCCTGTCTACGGCGAGGTTATCGTCTTCACCAC
CGCGATCGTGCTCATCCGTCTGCTGCCGCAGGGCATCTCCGGGCGCTTCTTCAAGGGGAACCTGTGA

Upstream 100 bases:

>100_bases
CGAACGACGTCAAGCAGTACATCATCAATCTCTGACGCCTGCCGGGTCCCGCCATCCGGCGGGACCCGGATTCATTGGAC
TGCCCTGAAAGACCTGACGC

Downstream 100 bases:

>100_bases
TGGACAAGCGCCTTCGTCTCGCGCTCCAGGCCGCCGGAACCGTCGTTGCCGTCGGCGTCATTGCGATCGTGCCGAGCGTG
ATCGAGCTGTTCGGCCTGAT

Product: branched chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MAIYVILALDVLNGISSLFLLCLGLAIIFGMMKIINLAHGEFIMLGAYATVISANAGVNIWIAMLIIAPLFVGIVGLVIE
RCLIRFLYGRLVDSMLATWGLSLLIIGIITTIYGNTQQGVPTPLGGFSIGSYQSSYYTLFLALMAAVMMAIIYGVMRYTR
FGLVARATMQNPAMAATLGVNPARVYMSTFALGAAVTGLAGGLLAPVSGITPVMGGAYVAKAFMTVVGGGAAILSGTLSA
ASLFGSVNQVGAYFTTPVYGEVIVFTTAIVLIRLLPQGISGRFFKGNL

Sequences:

>Translated_288_residues
MAIYVILALDVLNGISSLFLLCLGLAIIFGMMKIINLAHGEFIMLGAYATVISANAGVNIWIAMLIIAPLFVGIVGLVIE
RCLIRFLYGRLVDSMLATWGLSLLIIGIITTIYGNTQQGVPTPLGGFSIGSYQSSYYTLFLALMAAVMMAIIYGVMRYTR
FGLVARATMQNPAMAATLGVNPARVYMSTFALGAAVTGLAGGLLAPVSGITPVMGGAYVAKAFMTVVGGGAAILSGTLSA
ASLFGSVNQVGAYFTTPVYGEVIVFTTAIVLIRLLPQGISGRFFKGNL
>Mature_287_residues
AIYVILALDVLNGISSLFLLCLGLAIIFGMMKIINLAHGEFIMLGAYATVISANAGVNIWIAMLIIAPLFVGIVGLVIER
CLIRFLYGRLVDSMLATWGLSLLIIGIITTIYGNTQQGVPTPLGGFSIGSYQSSYYTLFLALMAAVMMAIIYGVMRYTRF
GLVARATMQNPAMAATLGVNPARVYMSTFALGAAVTGLAGGLLAPVSGITPVMGGAYVAKAFMTVVGGGAAILSGTLSAA
SLFGSVNQVGAYFTTPVYGEVIVFTTAIVLIRLLPQGISGRFFKGNL

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=295, Percent_Identity=28.4745762711864, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 30124; Mature: 29993

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIYVILALDVLNGISSLFLLCLGLAIIFGMMKIINLAHGEFIMLGAYATVISANAGVNI
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCHHH
WIAMLIIAPLFVGIVGLVIERCLIRFLYGRLVDSMLATWGLSLLIIGIITTIYGNTQQGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PTPLGGFSIGSYQSSYYTLFLALMAAVMMAIIYGVMRYTRFGLVARATMQNPAMAATLGV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NPARVYMSTFALGAAVTGLAGGLLAPVSGITPVMGGAYVAKAFMTVVGGGAAILSGTLSA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ASLFGSVNQVGAYFTTPVYGEVIVFTTAIVLIRLLPQGISGRFFKGNL
HHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AIYVILALDVLNGISSLFLLCLGLAIIFGMMKIINLAHGEFIMLGAYATVISANAGVNI
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCHHH
WIAMLIIAPLFVGIVGLVIERCLIRFLYGRLVDSMLATWGLSLLIIGIITTIYGNTQQGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PTPLGGFSIGSYQSSYYTLFLALMAAVMMAIIYGVMRYTRFGLVARATMQNPAMAATLGV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NPARVYMSTFALGAAVTGLAGGLLAPVSGITPVMGGAYVAKAFMTVVGGGAAILSGTLSA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ASLFGSVNQVGAYFTTPVYGEVIVFTTAIVLIRLLPQGISGRFFKGNL
HHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]