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The map label for this gene is rpfC [H]

Identifier: 146340985

GI number: 146340985

Start: 4243729

End: 4246044

Strand: Reverse

Name: rpfC [H]

Synonym: BRADO4056

Alternate gene names: 146340985

Gene position: 4246044-4243729 (Counterclockwise)

Preceding gene: 146340986

Following gene: 146340983

Centisome position: 56.94

GC content: 65.5

Gene sequence:

>2316_bases
ATGAATTGGCCTGGGGATCCCGCGACCTCGAAGCGAGCCGGCAATGGCAGTCCGCTGGGGGCATTCTTCCTTTGGATCGG
CGGTTTCAGCGCCATTGAAGAGCTCGATGACGACGCGCTCACCGAGCGCGATCGCCGGCGCATCCGTGCCCGGCAGATCG
ATGCCGTGGCGCGCCTCGTGCCGGTGACGATCGGCATCAATTTCGCCAACGCCGCCATCATCCTCGGCGTGTTCTGGAAT
ATCGTTTCCAATGTCTTCCTCATCGCCTGGGGAACGGCGATCGTCGTGTCCGGCGGCATGGCGCTGCGCGGCTGGTGGCG
CGCTCGCGAGTCGCGGCCGCAGGAGGCTTCCGAGCGCGCGATCCGGCGCATGATCGTGCAGGCGTTCTTTCTCGCTTGCA
TCTGGGGATCGCTCCCACTGATCGTGATGCCGCAGGTCGAGCCGCATCTGCAGATCATCGTCGGGTCGCTGATGACCGGA
ATGATCTCGGGCGGCGCATTCGCGATGTCGAGCGTCCCGCGCGGCGGGCTCGCCTACACCTGGACCCTGATGCTTTGCTC
GGTCGGGGCGTTGTTCCTCTGCGGCGGCGCGACCTATCTCGTGCTCGTCGTCTTCCTCTGCCTCTATACCTCGTTCATGG
TTCGTCATCTGGTGGCGCACGGCAACGTGTTCCTCGACAATCTGAAGGCGCAGATCCGCCACGAACGGCAGAACGAGACG
ATCTCGCTGCTCTTGAAGGAATTCCAGGAGAACGCAGCGAGCTGGCTGTGGCAGACCGATGCCGAGGGCCGCCTGATCGA
TGCGCCGCAGCGCTTCGCCGACGTGGCGCAGCTGCCACTCGATCAGCTCAAGGGCGAGCGTCTGATCGATACGCTGAAAT
ATCTCTGCCCCACCGACACCGCGACGCTCAAGACCCTCGCCGATCGCATGGCGCAACGGCTCTCGATTCCGGAGATCCTG
ATCCATGTCGTGGTCGCGGGCGGCGAGCGCAGGCGGTGGGCGCTGACGGCCCGCCCGGCGCGCGATCACGAGGGCAAGTT
TGCCGGCTATCGCGGCTTTGGCCGCGACGTCACCGAGCGTTGGCGCGCCGAGCAGGCGGAGGCCGAGAGCCGCGCCAAAT
CCGACTTCCTGGCGATGATGAGCCACGAGATCCGCACGCCGATGAACGGCGTTCTCGGCCTCGCCTCGACCCTGCTGGAA
ACCAAGCTCGACGATGAGCAGCGCCACGCGGTCATGACGATCCGCGAGTCCGGCGACAATCTGCAGCGCATCCTCAACGA
CATTCTCGATTTGTCGAAGCTCAACGCCGGCAAGCTCGAATTCGAAACGGTCGACTTCTCGCCGTCCGCGCTGGTGGAGG
CGGTCACCGCGATCATCGGCGTCAACGCCAAGTCGAAGAGCCTCTTGGTCAATGCCGACATCGATCCGAAGCTGCCGCCG
TCGCTGAAGGGCGACGTCGCGCGCATCCGCCAGGTCTTGATCAATCTCGCCTCGAACGCGGTGAAGTTCACCGAACGCGG
CGGCGTGACCATCGCCGTGTCGTGCCGGACGCGCGATGATCACAAGGCCACGATCGAATGGCGCGTCTCCGACACCGGCA
TCGGCATTCCCGCGGATCGCGTCGGCAAGCTGTTCACGGATTTCGCGCAGGCCGACGCCTCGATCAACCGCCGCTTCGGC
GGCACCGGGCTGGGGCTTGCGATCTCACGGCGCATCATCGAGCAGATGGGCGGCGCGATCGCGGTCTCATCCGTACAGGG
CGAAGGCTCGACCTTCCGCTTCAGCCTGACCTTGCCGTGGAGCGACAAGCAGATCTCCGATCAGCGCGGCGACCGCGTCG
GCGCTGGCGATCTCAAGGCGCGGATCGAGGCGCTGGGACGTCCGCTGCGCATCCTGATCGCCGAGGATGACGCCACCAAC
CGCATGGTGGTGTCGAAGATGCTGCAGGAATTTGCCGTCGACAAATGCATCGTGCCGGACGGTCTGCAGGCGGTGAACGC
GGCTTCCGAGCAGGCGTTCGACCTGGTGTTGATGGACGTCCGCATGCCTGAGATGGACGGCATCACCGCGACGCGGACCA
TTCGTGCGAAGGGTGGACGGCTCGCCGAACTGCCGATCATCGCGCTCACCGCAAATGCCTTCCCCGACGACATCAAGCAG
TGCCGAGAGGCGGGGATGACCGATTTCCTCGCCAAGCCGCTGCGCAAGCCGGCCATGGTGGCGGCGATGCTGAAGGCGAT
CGGCACGCCAGCTTCGACTGTCGAGGCGCCGCCGCTCGCGCCAGACGAGACGCCGGCCGCAACCGCCGAGGCCTGA

Upstream 100 bases:

>100_bases
GAAGGCGGTCGGTTCCGTAATTCTACGGGCGGGACAATTAACGCGGCTGAAGCCGCCGGTCAGGCATGGCAAGGGATCAC
AAGGAAGGTTCTGCGCGCTC

Downstream 100 bases:

>100_bases
CGCGGAGGAGGGGAAATCGCGCTGGATCAGCGAGTACCGATGTCTCTCACCCCAAGCCGTCATTCCGGGGCAAACGTCCC
ATGCAGCGGCGCCGCAGCTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 771; Mature: 771

Protein sequence:

>771_residues
MNWPGDPATSKRAGNGSPLGAFFLWIGGFSAIEELDDDALTERDRRRIRARQIDAVARLVPVTIGINFANAAIILGVFWN
IVSNVFLIAWGTAIVVSGGMALRGWWRARESRPQEASERAIRRMIVQAFFLACIWGSLPLIVMPQVEPHLQIIVGSLMTG
MISGGAFAMSSVPRGGLAYTWTLMLCSVGALFLCGGATYLVLVVFLCLYTSFMVRHLVAHGNVFLDNLKAQIRHERQNET
ISLLLKEFQENAASWLWQTDAEGRLIDAPQRFADVAQLPLDQLKGERLIDTLKYLCPTDTATLKTLADRMAQRLSIPEIL
IHVVVAGGERRRWALTARPARDHEGKFAGYRGFGRDVTERWRAEQAEAESRAKSDFLAMMSHEIRTPMNGVLGLASTLLE
TKLDDEQRHAVMTIRESGDNLQRILNDILDLSKLNAGKLEFETVDFSPSALVEAVTAIIGVNAKSKSLLVNADIDPKLPP
SLKGDVARIRQVLINLASNAVKFTERGGVTIAVSCRTRDDHKATIEWRVSDTGIGIPADRVGKLFTDFAQADASINRRFG
GTGLGLAISRRIIEQMGGAIAVSSVQGEGSTFRFSLTLPWSDKQISDQRGDRVGAGDLKARIEALGRPLRILIAEDDATN
RMVVSKMLQEFAVDKCIVPDGLQAVNAASEQAFDLVLMDVRMPEMDGITATRTIRAKGGRLAELPIIALTANAFPDDIKQ
CREAGMTDFLAKPLRKPAMVAAMLKAIGTPASTVEAPPLAPDETPAATAEA

Sequences:

>Translated_771_residues
MNWPGDPATSKRAGNGSPLGAFFLWIGGFSAIEELDDDALTERDRRRIRARQIDAVARLVPVTIGINFANAAIILGVFWN
IVSNVFLIAWGTAIVVSGGMALRGWWRARESRPQEASERAIRRMIVQAFFLACIWGSLPLIVMPQVEPHLQIIVGSLMTG
MISGGAFAMSSVPRGGLAYTWTLMLCSVGALFLCGGATYLVLVVFLCLYTSFMVRHLVAHGNVFLDNLKAQIRHERQNET
ISLLLKEFQENAASWLWQTDAEGRLIDAPQRFADVAQLPLDQLKGERLIDTLKYLCPTDTATLKTLADRMAQRLSIPEIL
IHVVVAGGERRRWALTARPARDHEGKFAGYRGFGRDVTERWRAEQAEAESRAKSDFLAMMSHEIRTPMNGVLGLASTLLE
TKLDDEQRHAVMTIRESGDNLQRILNDILDLSKLNAGKLEFETVDFSPSALVEAVTAIIGVNAKSKSLLVNADIDPKLPP
SLKGDVARIRQVLINLASNAVKFTERGGVTIAVSCRTRDDHKATIEWRVSDTGIGIPADRVGKLFTDFAQADASINRRFG
GTGLGLAISRRIIEQMGGAIAVSSVQGEGSTFRFSLTLPWSDKQISDQRGDRVGAGDLKARIEALGRPLRILIAEDDATN
RMVVSKMLQEFAVDKCIVPDGLQAVNAASEQAFDLVLMDVRMPEMDGITATRTIRAKGGRLAELPIIALTANAFPDDIKQ
CREAGMTDFLAKPLRKPAMVAAMLKAIGTPASTVEAPPLAPDETPAATAEA
>Mature_771_residues
MNWPGDPATSKRAGNGSPLGAFFLWIGGFSAIEELDDDALTERDRRRIRARQIDAVARLVPVTIGINFANAAIILGVFWN
IVSNVFLIAWGTAIVVSGGMALRGWWRARESRPQEASERAIRRMIVQAFFLACIWGSLPLIVMPQVEPHLQIIVGSLMTG
MISGGAFAMSSVPRGGLAYTWTLMLCSVGALFLCGGATYLVLVVFLCLYTSFMVRHLVAHGNVFLDNLKAQIRHERQNET
ISLLLKEFQENAASWLWQTDAEGRLIDAPQRFADVAQLPLDQLKGERLIDTLKYLCPTDTATLKTLADRMAQRLSIPEIL
IHVVVAGGERRRWALTARPARDHEGKFAGYRGFGRDVTERWRAEQAEAESRAKSDFLAMMSHEIRTPMNGVLGLASTLLE
TKLDDEQRHAVMTIRESGDNLQRILNDILDLSKLNAGKLEFETVDFSPSALVEAVTAIIGVNAKSKSLLVNADIDPKLPP
SLKGDVARIRQVLINLASNAVKFTERGGVTIAVSCRTRDDHKATIEWRVSDTGIGIPADRVGKLFTDFAQADASINRRFG
GTGLGLAISRRIIEQMGGAIAVSSVQGEGSTFRFSLTLPWSDKQISDQRGDRVGAGDLKARIEALGRPLRILIAEDDATN
RMVVSKMLQEFAVDKCIVPDGLQAVNAASEQAFDLVLMDVRMPEMDGITATRTIRAKGGRLAELPIIALTANAFPDDIKQ
CREAGMTDFLAKPLRKPAMVAAMLKAIGTPASTVEAPPLAPDETPAATAEA

Specific function: Involved in the positive regulation of synthesis of extracellular enzymes and polysaccharide, and hence in pathogenicity. Can restore function to the non-pathogenic mutant 8237 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=411, Percent_Identity=36.4963503649635, Blast_Score=242, Evalue=8e-65,
Organism=Escherichia coli, GI1789149, Length=380, Percent_Identity=33.1578947368421, Blast_Score=206, Evalue=6e-54,
Organism=Escherichia coli, GI1788713, Length=420, Percent_Identity=33.8095238095238, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI87081816, Length=385, Percent_Identity=32.2077922077922, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=38.7096774193548, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=32.7354260089686, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI87082128, Length=250, Percent_Identity=30, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788549, Length=368, Percent_Identity=27.1739130434783, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1786600, Length=251, Percent_Identity=30.2788844621514, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788393, Length=220, Percent_Identity=28.6363636363636, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1790300, Length=255, Percent_Identity=30.1960784313725, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=26.5822784810127, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786783, Length=237, Percent_Identity=27.8481012658228, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790437, Length=139, Percent_Identity=33.0935251798561, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788191, Length=109, Percent_Identity=31.1926605504587, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1789808, Length=239, Percent_Identity=24.6861924686192, Blast_Score=63, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=137, Percent_Identity=33.5766423357664, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322044, Length=117, Percent_Identity=35.042735042735, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84156; Mature: 84156

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWPGDPATSKRAGNGSPLGAFFLWIGGFSAIEELDDDALTERDRRRIRARQIDAVARLV
CCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
PVTIGINFANAAIILGVFWNIVSNVFLIAWGTAIVVSGGMALRGWWRARESRPQEASERA
HHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHCCCCHHHHHHH
IRRMIVQAFFLACIWGSLPLIVMPQVEPHLQIIVGSLMTGMISGGAFAMSSVPRGGLAYT
HHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHH
WTLMLCSVGALFLCGGATYLVLVVFLCLYTSFMVRHLVAHGNVFLDNLKAQIRHERQNET
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHH
ISLLLKEFQENAASWLWQTDAEGRLIDAPQRFADVAQLPLDQLKGERLIDTLKYLCPTDT
HHHHHHHHHHHHHHHEEECCCCCCEECCHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCH
ATLKTLADRMAQRLSIPEILIHVVVAGGERRRWALTARPARDHEGKFAGYRGFGRDVTER
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHH
WRAEQAEAESRAKSDFLAMMSHEIRTPMNGVLGLASTLLETKLDDEQRHAVMTIRESGDN
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHEEEEECCCCCH
LQRILNDILDLSKLNAGKLEFETVDFSPSALVEAVTAIIGVNAKSKSLLVNADIDPKLPP
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
SLKGDVARIRQVLINLASNAVKFTERGGVTIAVSCRTRDDHKATIEWRVSDTGIGIPADR
CCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCCCCEEEEEEEECCCCCCCHHH
VGKLFTDFAQADASINRRFGGTGLGLAISRRIIEQMGGAIAVSSVQGEGSTFRFSLTLPW
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEECC
SDKQISDQRGDRVGAGDLKARIEALGRPLRILIAEDDATNRMVVSKMLQEFAVDKCIVPD
CCCHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
GLQAVNAASEQAFDLVLMDVRMPEMDGITATRTIRAKGGRLAELPIIALTANAFPDDIKQ
CHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEEEECCCCEEEECCEEEEECCCCHHHHHH
CREAGMTDFLAKPLRKPAMVAAMLKAIGTPASTVEAPPLAPDETPAATAEA
HHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNWPGDPATSKRAGNGSPLGAFFLWIGGFSAIEELDDDALTERDRRRIRARQIDAVARLV
CCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
PVTIGINFANAAIILGVFWNIVSNVFLIAWGTAIVVSGGMALRGWWRARESRPQEASERA
HHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHCCCCHHHHHHH
IRRMIVQAFFLACIWGSLPLIVMPQVEPHLQIIVGSLMTGMISGGAFAMSSVPRGGLAYT
HHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHH
WTLMLCSVGALFLCGGATYLVLVVFLCLYTSFMVRHLVAHGNVFLDNLKAQIRHERQNET
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHH
ISLLLKEFQENAASWLWQTDAEGRLIDAPQRFADVAQLPLDQLKGERLIDTLKYLCPTDT
HHHHHHHHHHHHHHHEEECCCCCCEECCHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCH
ATLKTLADRMAQRLSIPEILIHVVVAGGERRRWALTARPARDHEGKFAGYRGFGRDVTER
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHH
WRAEQAEAESRAKSDFLAMMSHEIRTPMNGVLGLASTLLETKLDDEQRHAVMTIRESGDN
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHEEEEECCCCCH
LQRILNDILDLSKLNAGKLEFETVDFSPSALVEAVTAIIGVNAKSKSLLVNADIDPKLPP
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
SLKGDVARIRQVLINLASNAVKFTERGGVTIAVSCRTRDDHKATIEWRVSDTGIGIPADR
CCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCCCCEEEEEEEECCCCCCCHHH
VGKLFTDFAQADASINRRFGGTGLGLAISRRIIEQMGGAIAVSSVQGEGSTFRFSLTLPW
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEECC
SDKQISDQRGDRVGAGDLKARIEALGRPLRILIAEDDATNRMVVSKMLQEFAVDKCIVPD
CCCHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
GLQAVNAASEQAFDLVLMDVRMPEMDGITATRTIRAKGGRLAELPIIALTANAFPDDIKQ
CHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEEEECCCCEEEECCEEEEECCCCHHHHHH
CREAGMTDFLAKPLRKPAMVAAMLKAIGTPASTVEAPPLAPDETPAATAEA
HHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1645442 [H]