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The map label for this gene is appC [H]

Identifier: 146340893

GI number: 146340893

Start: 4141714

End: 4142544

Strand: Direct

Name: appC [H]

Synonym: BRADO3959

Alternate gene names: 146340893

Gene position: 4141714-4142544 (Clockwise)

Preceding gene: 146340892

Following gene: 146340894

Centisome position: 55.54

GC content: 67.63

Gene sequence:

>831_bases
ATGGATGCGGTGAAGCGCTATTTCCGCAGCCCCGCCGCGGTGCTCGGCCTCGTGCTGCTGCTGATCGTCATCGGCATGGC
GCTCAGCGCGGGCTATTTCTATCCGCGCGACCCGCTTGCGCTGGCCGGCCGTCCGCTGGTCTGGCCGTTCGCCAATCCGC
GGTTCCTGCTCGGCACCGACAATTCGGGCCGCGACATTGCCGCCCAGATCTTTCACGGCGCCCGCATCTCGCTCCTGATC
GGCGGCGTGGCCACGCTGATCGCGGTGACGATCGGCGTCTTGGTCGGGGCGCTCGCGGGCTATTACGGCGGCTGGATCGA
CAACATCCTGATGCGCATCACCGAGGCGTTTCAGACCTTGCCGAACTTCGTGCTGCTGCTGGTGCTGGTCGCCGTGTTCG
GCTCGACCTTGACGACGGTGACGATCGCCGTCGGCATCGTGTCCTGGCCGGCGCCGGCGCGGCTGACGCGGGCGGAGTTC
CTGTCGCTGCGCAGCCGCGAATTCGTCCAGGCCGGCCGCACGCTCGGCATGCGCGATGCGCAACTGATCCTGCGCGAGAT
CCTGCCCAATGCCTTGCCGCCCGTCATCGTCTATGCGGGTGTGGTGATGGCGGTCGCGATCCTGTTGGAAAGCGCGCTCG
CCTTCCTGCGGCTGTCCGATGCCAACGTCGCCTCCTGGGGCAACCTGATCGGTCTCGGGCGCGACGTGCTGCGGGTCCAA
TGGTACGTCTCGGCCATTCCCGGCGTCGCCATCCTGGTCACCGTACTCGCGGTGTCGCTGGTCGGCCAGGGCCTCAACGA
TGCGCTGAACCCGCGGCTGAAGCAGCGATGA

Upstream 100 bases:

>100_bases
GGCATCGTCTTCGTCTCGGCGCTTCTGGTGATCGCGGTCAATTTCGTCACGGACCTGCTCTACGCGCGGCTCGATCCGCG
CATCGCGGCGGAGAGCTAGC

Downstream 100 bases:

>100_bases
GTTCGCCCGATCCCATTCTCACCGTCGACCGTCTGAGCGTCCGCCTGCCCAAGGGCGCGGACCGCGTCCATGCGATCTCC
GAGGTCTCGCTGTCGATTGC

Product: putative ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MDAVKRYFRSPAAVLGLVLLLIVIGMALSAGYFYPRDPLALAGRPLVWPFANPRFLLGTDNSGRDIAAQIFHGARISLLI
GGVATLIAVTIGVLVGALAGYYGGWIDNILMRITEAFQTLPNFVLLLVLVAVFGSTLTTVTIAVGIVSWPAPARLTRAEF
LSLRSREFVQAGRTLGMRDAQLILREILPNALPPVIVYAGVVMAVAILLESALAFLRLSDANVASWGNLIGLGRDVLRVQ
WYVSAIPGVAILVTVLAVSLVGQGLNDALNPRLKQR

Sequences:

>Translated_276_residues
MDAVKRYFRSPAAVLGLVLLLIVIGMALSAGYFYPRDPLALAGRPLVWPFANPRFLLGTDNSGRDIAAQIFHGARISLLI
GGVATLIAVTIGVLVGALAGYYGGWIDNILMRITEAFQTLPNFVLLLVLVAVFGSTLTTVTIAVGIVSWPAPARLTRAEF
LSLRSREFVQAGRTLGMRDAQLILREILPNALPPVIVYAGVVMAVAILLESALAFLRLSDANVASWGNLIGLGRDVLRVQ
WYVSAIPGVAILVTVLAVSLVGQGLNDALNPRLKQR
>Mature_276_residues
MDAVKRYFRSPAAVLGLVLLLIVIGMALSAGYFYPRDPLALAGRPLVWPFANPRFLLGTDNSGRDIAAQIFHGARISLLI
GGVATLIAVTIGVLVGALAGYYGGWIDNILMRITEAFQTLPNFVLLLVLVAVFGSTLTTVTIAVGIVSWPAPARLTRAEF
LSLRSREFVQAGRTLGMRDAQLILREILPNALPPVIVYAGVVMAVAILLESALAFLRLSDANVASWGNLIGLGRDVLRVQ
WYVSAIPGVAILVTVLAVSLVGQGLNDALNPRLKQR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=271, Percent_Identity=34.3173431734317, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787760, Length=264, Percent_Identity=35.2272727272727, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787498, Length=276, Percent_Identity=34.7826086956522, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789964, Length=221, Percent_Identity=41.1764705882353, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788505, Length=229, Percent_Identity=32.7510917030568, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789889, Length=248, Percent_Identity=33.0645161290323, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787549, Length=273, Percent_Identity=26.007326007326, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29537; Mature: 29537

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAVKRYFRSPAAVLGLVLLLIVIGMALSAGYFYPRDPLALAGRPLVWPFANPRFLLGTD
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEECCCCCCEEEEECC
NSGRDIAAQIFHGARISLLIGGVATLIAVTIGVLVGALAGYYGGWIDNILMRITEAFQTL
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PNFVLLLVLVAVFGSTLTTVTIAVGIVSWPAPARLTRAEFLSLRSREFVQAGRTLGMRDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
QLILREILPNALPPVIVYAGVVMAVAILLESALAFLRLSDANVASWGNLIGLGRDVLRVQ
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
WYVSAIPGVAILVTVLAVSLVGQGLNDALNPRLKQR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHCCC
>Mature Secondary Structure
MDAVKRYFRSPAAVLGLVLLLIVIGMALSAGYFYPRDPLALAGRPLVWPFANPRFLLGTD
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEECCCCCCEEEEECC
NSGRDIAAQIFHGARISLLIGGVATLIAVTIGVLVGALAGYYGGWIDNILMRITEAFQTL
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PNFVLLLVLVAVFGSTLTTVTIAVGIVSWPAPARLTRAEFLSLRSREFVQAGRTLGMRDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
QLILREILPNALPPVIVYAGVVMAVAILLESALAFLRLSDANVASWGNLIGLGRDVLRVQ
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
WYVSAIPGVAILVTVLAVSLVGQGLNDALNPRLKQR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]