Click here to switch to the map view.

The map label for this gene is exaA [H]

Identifier: 146340834

GI number: 146340834

Start: 4067565

End: 4069307

Strand: Reverse

Name: exaA [H]

Synonym: BRADO3897

Alternate gene names: 146340834

Gene position: 4069307-4067565 (Counterclockwise)

Preceding gene: 146340835

Following gene: 146340825

Centisome position: 54.57

GC content: 63.28

Gene sequence:

>1743_bases
ATGTCCATCACGTCCCGCACGATCAAGCAATGTCTTCTGTCGAGCACCGTCGCATTCACCTGTCTCGCCGCGCCCGCGGC
AATGGCGGGCCCGATAGAGAACTACAGTCCGGTTACACCTGCGCGGCTCGAGAATCCCGAGCCCGGCAACTGGATGCTCT
ATCGCCGCACCTATGATGGCCAGGGCTACAGCCCGCTTGACCAGATCAACACCACCAACGTCAAGAGCATGGTGCCGGTC
TGGACCTTCGCGACCGGCGTGATCGAGGGCCACGAGTCACCGCCGCTGGTCAACAACGGGGTCATGTTTATCACCACGCC
GATGGGGCAGGTCATTGCGCTGAATGCCAAGACCGGCGATCAGTACTGGCGCTACAAGCGCGAGCTGCCCGAGGATCTTT
TCCAGCTGCATCCGACCAACCGCGGCGTCGGACTTTGGCAGGACAAGCTATATCTCGCCACGACCGACGATCATCTGGTC
GCGCTCGACGCCAAGACCGGCAAGGTGCTGTGGGACAAGAAGGTCCAGGACTACAAGAAAGGCCAGTATCTCACGCTGAT
GCCGCTGATCGTCGACGGCAAGGTGATGGTCGGCGGCTCGGGCGGAGAGTTCGGCGTCCGCGGCTATGTCGCCGCCTACG
ATGCCGAGGACGGCAAGGAGCTGTGGCGCACCTTCACCATTCCGGCCGAGGGCGAGCCAGGGCATGACACCTGGAGCGGC
GACGACTGGAAGAATGGCGGCGGCTCCGCATGGATGACCGGTACCTATGACAAGGACACCAAGACGGTTTATTGGGGTGT
CGGTAACGCCGCCCCGTGGCCGGGTGGAATGCATCCCGGCGACAATCTCTACACCAGTTCGGTGATCGCGCTGGATCCAG
CGACGGGCAAGATCAAGACGCACTTCCAGTACCACCAGAACGATTCATGGGACTGGGACGAGGTCGATGCGCCGATGCTG
GTCGACCTGCAGCGCGACGGCCGCAGCTTCAAGAGCCTGATCCATCCCGGCCGCGATGCCATTTTCTGGGTGCTGGAGCG
CACGCCGGAGCGCATCAACTACGTCAACGGCTGGAATTTCGTTCACACCGACGTCTGGAAGGGGATCGAGCCCGAGACCG
GTCGACCGATCGTCGATCCCGCGCACAAGCCGACGCTCGGCAAGCGGGTCGACTTCTGTCCCTCGCTGTGGGGCGGCAAG
GACTGGCCGTCGGCCGCGTATAGCCAGAAGACCCGCTTCGTTTACGTGCCGGCCAATGAGAACTTCTGCGGCGGCTTCAC
CGGCGAGAAGCTGCCGCTGGTTCCGGGACAGCTCTGGCTCGGCACCAAGGCAGAGGACATCGGGCTGACGGTGCGGCCCG
GTGCAGACCATTTCGGCGAGCTGCAGGCATGGGATCCGGCCTCCGGCAAGAAAGTCTGGTCGCACAACTTCCCGAAGTCG
CAGCTGTTCGGCTCGGTGACGGCGACCGCCGGCGATCTCGTCCTGGTCGGCGGGACCAACGACCGGATGTTCCGGGCCTT
CCATGCCAAGACCGGCGAGCTGCTGTGGGAGCAGAAGACCAACTCGGGCATCATGGGCATGCCCGTTTCCTACGAGGTCG
ACGGCACGCAGTATATCGCCGTGCAGTCAGGCTGGGGCGTCGACGCGCAACGCATCCAGGATGCGCTTGCCAAGGGCAAC
GTTGGACTCGAGGACAACGTCCCCCAGGGCGGTGTAGTCTGGGTTTTCGCCGTCAAGAAATAG

Upstream 100 bases:

>100_bases
TCTCGTATGCCTATCGGAACTCGCGTCGTCACGACCCAAACGTCGTGAACATCGTCACGACGAGCAAAGAAGCGAACAAC
GAAGCAGGGGAGGTTTGTCC

Downstream 100 bases:

>100_bases
CTGAAGAAGCCGACGTGGCGGCGGCCGCGTGCCGCCGCTATGTCGGCGCCGGAGGTGTATCAACCGGTACGATTGTGCTC
CGACCTTGGAGGTCACGCGC

Product: putative alcohol dehydrogenase (acceptor)

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 580; Mature: 579

Protein sequence:

>580_residues
MSITSRTIKQCLLSSTVAFTCLAAPAAMAGPIENYSPVTPARLENPEPGNWMLYRRTYDGQGYSPLDQINTTNVKSMVPV
WTFATGVIEGHESPPLVNNGVMFITTPMGQVIALNAKTGDQYWRYKRELPEDLFQLHPTNRGVGLWQDKLYLATTDDHLV
ALDAKTGKVLWDKKVQDYKKGQYLTLMPLIVDGKVMVGGSGGEFGVRGYVAAYDAEDGKELWRTFTIPAEGEPGHDTWSG
DDWKNGGGSAWMTGTYDKDTKTVYWGVGNAAPWPGGMHPGDNLYTSSVIALDPATGKIKTHFQYHQNDSWDWDEVDAPML
VDLQRDGRSFKSLIHPGRDAIFWVLERTPERINYVNGWNFVHTDVWKGIEPETGRPIVDPAHKPTLGKRVDFCPSLWGGK
DWPSAAYSQKTRFVYVPANENFCGGFTGEKLPLVPGQLWLGTKAEDIGLTVRPGADHFGELQAWDPASGKKVWSHNFPKS
QLFGSVTATAGDLVLVGGTNDRMFRAFHAKTGELLWEQKTNSGIMGMPVSYEVDGTQYIAVQSGWGVDAQRIQDALAKGN
VGLEDNVPQGGVVWVFAVKK

Sequences:

>Translated_580_residues
MSITSRTIKQCLLSSTVAFTCLAAPAAMAGPIENYSPVTPARLENPEPGNWMLYRRTYDGQGYSPLDQINTTNVKSMVPV
WTFATGVIEGHESPPLVNNGVMFITTPMGQVIALNAKTGDQYWRYKRELPEDLFQLHPTNRGVGLWQDKLYLATTDDHLV
ALDAKTGKVLWDKKVQDYKKGQYLTLMPLIVDGKVMVGGSGGEFGVRGYVAAYDAEDGKELWRTFTIPAEGEPGHDTWSG
DDWKNGGGSAWMTGTYDKDTKTVYWGVGNAAPWPGGMHPGDNLYTSSVIALDPATGKIKTHFQYHQNDSWDWDEVDAPML
VDLQRDGRSFKSLIHPGRDAIFWVLERTPERINYVNGWNFVHTDVWKGIEPETGRPIVDPAHKPTLGKRVDFCPSLWGGK
DWPSAAYSQKTRFVYVPANENFCGGFTGEKLPLVPGQLWLGTKAEDIGLTVRPGADHFGELQAWDPASGKKVWSHNFPKS
QLFGSVTATAGDLVLVGGTNDRMFRAFHAKTGELLWEQKTNSGIMGMPVSYEVDGTQYIAVQSGWGVDAQRIQDALAKGN
VGLEDNVPQGGVVWVFAVKK
>Mature_579_residues
SITSRTIKQCLLSSTVAFTCLAAPAAMAGPIENYSPVTPARLENPEPGNWMLYRRTYDGQGYSPLDQINTTNVKSMVPVW
TFATGVIEGHESPPLVNNGVMFITTPMGQVIALNAKTGDQYWRYKRELPEDLFQLHPTNRGVGLWQDKLYLATTDDHLVA
LDAKTGKVLWDKKVQDYKKGQYLTLMPLIVDGKVMVGGSGGEFGVRGYVAAYDAEDGKELWRTFTIPAEGEPGHDTWSGD
DWKNGGGSAWMTGTYDKDTKTVYWGVGNAAPWPGGMHPGDNLYTSSVIALDPATGKIKTHFQYHQNDSWDWDEVDAPMLV
DLQRDGRSFKSLIHPGRDAIFWVLERTPERINYVNGWNFVHTDVWKGIEPETGRPIVDPAHKPTLGKRVDFCPSLWGGKD
WPSAAYSQKTRFVYVPANENFCGGFTGEKLPLVPGQLWLGTKAEDIGLTVRPGADHFGELQAWDPASGKKVWSHNFPKSQ
LFGSVTATAGDLVLVGGTNDRMFRAFHAKTGELLWEQKTNSGIMGMPVSYEVDGTQYIAVQSGWGVDAQRIQDALAKGNV
GLEDNVPQGGVVWVFAVKK

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=362, Percent_Identity=27.6243093922652, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 64041; Mature: 63910

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITSRTIKQCLLSSTVAFTCLAAPAAMAGPIENYSPVTPARLENPEPGNWMLYRRTYDG
CCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHCCCCCCCCEEEEEEEECC
QGYSPLDQINTTNVKSMVPVWTFATGVIEGHESPPLVNNGVMFITTPMGQVIALNAKTGD
CCCCCHHHCCCCCHHHHCHHHEEEEHEEECCCCCCEECCCEEEEECCCCEEEEEECCCCH
QYWRYKRELPEDLFQLHPTNRGVGLWQDKLYLATTDDHLVALDAKTGKVLWDKKVQDYKK
HHHHHHHHCCHHHHHCCCCCCCCCEEECEEEEEECCCEEEEEECCCCCEEECCHHHHHHC
GQYLTLMPLIVDGKVMVGGSGGEFGVRGYVAAYDAEDGKELWRTFTIPAEGEPGHDTWSG
CCEEEEEEEEECCEEEECCCCCCCCCEEEEEEECCCCCHHHHEEEECCCCCCCCCCCCCC
DDWKNGGGSAWMTGTYDKDTKTVYWGVGNAAPWPGGMHPGDNLYTSSVIALDPATGKIKT
CCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCEEECEEEEECCCCCCEEE
HFQYHQNDSWDWDEVDAPMLVDLQRDGRSFKSLIHPGRDAIFWVLERTPERINYVNGWNF
EEEECCCCCCCHHHCCCCEEEEECCCCHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCE
VHTDVWKGIEPETGRPIVDPAHKPTLGKRVDFCPSLWGGKDWPSAAYSQKTRFVYVPANE
EEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEECCC
NFCGGFTGEKLPLVPGQLWLGTKAEDIGLTVRPGADHFGELQAWDPASGKKVWSHNFPKS
CCCCCCCCCCCCCCCCCEEECCCCHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QLFGSVTATAGDLVLVGGTNDRMFRAFHAKTGELLWEQKTNSGIMGMPVSYEVDGTQYIA
HHCEEEEECCCCEEEEECCCCCEEEEECCCCCCEEEEECCCCCEECCCEEEEECCEEEEE
VQSGWGVDAQRIQDALAKGNVGLEDNVPQGGVVWVFAVKK
EECCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
SITSRTIKQCLLSSTVAFTCLAAPAAMAGPIENYSPVTPARLENPEPGNWMLYRRTYDG
CCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHCCCCCCCCEEEEEEEECC
QGYSPLDQINTTNVKSMVPVWTFATGVIEGHESPPLVNNGVMFITTPMGQVIALNAKTGD
CCCCCHHHCCCCCHHHHCHHHEEEEHEEECCCCCCEECCCEEEEECCCCEEEEEECCCCH
QYWRYKRELPEDLFQLHPTNRGVGLWQDKLYLATTDDHLVALDAKTGKVLWDKKVQDYKK
HHHHHHHHCCHHHHHCCCCCCCCCEEECEEEEEECCCEEEEEECCCCCEEECCHHHHHHC
GQYLTLMPLIVDGKVMVGGSGGEFGVRGYVAAYDAEDGKELWRTFTIPAEGEPGHDTWSG
CCEEEEEEEEECCEEEECCCCCCCCCEEEEEEECCCCCHHHHEEEECCCCCCCCCCCCCC
DDWKNGGGSAWMTGTYDKDTKTVYWGVGNAAPWPGGMHPGDNLYTSSVIALDPATGKIKT
CCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCEEECEEEEECCCCCCEEE
HFQYHQNDSWDWDEVDAPMLVDLQRDGRSFKSLIHPGRDAIFWVLERTPERINYVNGWNF
EEEECCCCCCCHHHCCCCEEEEECCCCHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCE
VHTDVWKGIEPETGRPIVDPAHKPTLGKRVDFCPSLWGGKDWPSAAYSQKTRFVYVPANE
EEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEECCC
NFCGGFTGEKLPLVPGQLWLGTKAEDIGLTVRPGADHFGELQAWDPASGKKVWSHNFPKS
CCCCCCCCCCCCCCCCCEEECCCCHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QLFGSVTATAGDLVLVGGTNDRMFRAFHAKTGELLWEQKTNSGIMGMPVSYEVDGTQYIA
HHCEEEEECCCCEEEEECCCCCEEEEECCCCCCEEEEECCCCCEECCCEEEEECCEEEEE
VQSGWGVDAQRIQDALAKGNVGLEDNVPQGGVVWVFAVKK
EECCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]