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The map label for this gene is livM [H]

Identifier: 146340780

GI number: 146340780

Start: 4011637

End: 4012566

Strand: Reverse

Name: livM [H]

Synonym: BRADO3838

Alternate gene names: 146340780

Gene position: 4012566-4011637 (Counterclockwise)

Preceding gene: 146340781

Following gene: 146340779

Centisome position: 53.81

GC content: 66.99

Gene sequence:

>930_bases
ATGCCGGCATTCGTCTCCTCCCGGCTGTTCTGGATCGGCGCGCTCACCGTGATCGTCGCTCTCCTGCTGCCGTCCTACGT
CTCCGGCTACGTGCTGGGATTGCTGACCGTCGCGTACTACACGGCCGTGTTCGCGATGTCCTGGGACCTGTTGTTCGGCT
TCGCCGGCGAGGTCAATTTCGGGCCGACCTTCCTGATCGGCGTCGGCGCCTATACGGCCGGCATTCTCGACGCGCATTAC
TCGCCGGGGCTGTCGATCTGGATCTGCATCGCCGCCGGCGCGCTGGCCGCGGTCGTCGGCGGTGTGGTCCTGGCGCTGCC
GGCGCTGCGCGTCAGCGGGCCGTATTTCGGCCTGACGACCTTGGTCGCGGTGCTGATGCTGCAGAACTTCATCGTCGTCG
CGGCCGGGCTGACCGGCGGTGAAATCGGCCTCGCCGTGCCCGACGTGATCTCGATCGACGCCAAGACGAACTACTGGATC
GCGCTCGGCTTCATGCTGGTGTCGGGCGCCATCCTGTTCGGCCTGTCCCGCAGCGCCATCGGCCTGATCCTGCAGGCCAG
CGGCCAGGACAAGATCCAGGCCGGCGCGCTCGGCTTCAACGTCACCAAGCACAAGCTGGCGGCGTTCGTGGTCAGCGCGT
TCTTCTCCGGCCTCGCCGGCGCGCTGATGGTGTTCTACATGGGCACCGCGTCCGTCTCGACCTTCGTCGATGTCGGCGTC
GGCGTGCAGATCATCATCGCTGCCGTGCTCGGCGGCCGGCGCACCGTCATCGGCGCCGCGATCGGCGCGATCTTCCTGAT
CGGCATGGGCGAGCTGCTGCGGCCGCTCGGAGAGCTCGCCACCTTGATCGTCTCGGTGATTGCGCTGGTGGTCATCCTGT
TCTTCCCCGACGGCTTCCTCGGCATCATCAGGGGAGGGGCCAAAGCATGA

Upstream 100 bases:

>100_bases
CCTATCTGATCTCGCCGGCCTACCGGACGATTCCGGCGCTTTTGCTGCTCGTCGTCGTGATGTATCTGCGCCCGCAAGGG
CTGTTCGGACGGAGGTGAGC

Downstream 100 bases:

>100_bases
CGCAAGCTCCGATGCTGGAGGTCAGCGGCCTCACCAAGCGGTTCGGTGGCCTGGTCGCCGTCAAGAATCTGAGCTTCTCG
ATTCGACCCGGCGAGATCCT

Product: putative branched-chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein M [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MPAFVSSRLFWIGALTVIVALLLPSYVSGYVLGLLTVAYYTAVFAMSWDLLFGFAGEVNFGPTFLIGVGAYTAGILDAHY
SPGLSIWICIAAGALAAVVGGVVLALPALRVSGPYFGLTTLVAVLMLQNFIVVAAGLTGGEIGLAVPDVISIDAKTNYWI
ALGFMLVSGAILFGLSRSAIGLILQASGQDKIQAGALGFNVTKHKLAAFVVSAFFSGLAGALMVFYMGTASVSTFVDVGV
GVQIIIAAVLGGRRTVIGAAIGAIFLIGMGELLRPLGELATLIVSVIALVVILFFPDGFLGIIRGGAKA

Sequences:

>Translated_309_residues
MPAFVSSRLFWIGALTVIVALLLPSYVSGYVLGLLTVAYYTAVFAMSWDLLFGFAGEVNFGPTFLIGVGAYTAGILDAHY
SPGLSIWICIAAGALAAVVGGVVLALPALRVSGPYFGLTTLVAVLMLQNFIVVAAGLTGGEIGLAVPDVISIDAKTNYWI
ALGFMLVSGAILFGLSRSAIGLILQASGQDKIQAGALGFNVTKHKLAAFVVSAFFSGLAGALMVFYMGTASVSTFVDVGV
GVQIIIAAVLGGRRTVIGAAIGAIFLIGMGELLRPLGELATLIVSVIALVVILFFPDGFLGIIRGGAKA
>Mature_308_residues
PAFVSSRLFWIGALTVIVALLLPSYVSGYVLGLLTVAYYTAVFAMSWDLLFGFAGEVNFGPTFLIGVGAYTAGILDAHYS
PGLSIWICIAAGALAAVVGGVVLALPALRVSGPYFGLTTLVAVLMLQNFIVVAAGLTGGEIGLAVPDVISIDAKTNYWIA
LGFMLVSGAILFGLSRSAIGLILQASGQDKIQAGALGFNVTKHKLAAFVVSAFFSGLAGALMVFYMGTASVSTFVDVGVG
VQIIIAAVLGGRRTVIGAAIGAIFLIGMGELLRPLGELATLIVSVIALVVILFFPDGFLGIIRGGAKA

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=275, Percent_Identity=26.9090909090909, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 31684; Mature: 31553

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAFVSSRLFWIGALTVIVALLLPSYVSGYVLGLLTVAYYTAVFAMSWDLLFGFAGEVNF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GPTFLIGVGAYTAGILDAHYSPGLSIWICIAAGALAAVVGGVVLALPALRVSGPYFGLTT
CCEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LVAVLMLQNFIVVAAGLTGGEIGLAVPDVISIDAKTNYWIALGFMLVSGAILFGLSRSAI
HHHHHHHHHHHHHEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHH
GLILQASGQDKIQAGALGFNVTKHKLAAFVVSAFFSGLAGALMVFYMGTASVSTFVDVGV
EEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVQIIIAAVLGGRRTVIGAAIGAIFLIGMGELLRPLGELATLIVSVIALVVILFFPDGFL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GIIRGGAKA
HHHCCCCCC
>Mature Secondary Structure 
PAFVSSRLFWIGALTVIVALLLPSYVSGYVLGLLTVAYYTAVFAMSWDLLFGFAGEVNF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC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HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]