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The map label for this gene is atoS [C]

Identifier: 146340371

GI number: 146340371

Start: 3590690

End: 3592786

Strand: Reverse

Name: atoS [C]

Synonym: BRADO3399

Alternate gene names: 146340371

Gene position: 3592786-3590690 (Counterclockwise)

Preceding gene: 146340372

Following gene: 146340370

Centisome position: 48.18

GC content: 67.72

Gene sequence:

>2097_bases
GTGAGTTCCGCAGAGATCGACACGCTCCGCCGGCGCCTGCGGGAGCTCGAAAGTGAAAATGCCCGGCTGCAGGCGCGGTT
CGCCGCCGACGCCGGCAAACGCGCTGAGGCCGAAACAGCTTTGGCCGAAAGCGAGGAGCGCTATCGGACGCTGTTCAACT
CGATCGACGAAGGCTTCTGCATCATCGAGTTCTTCGACGGCCCGCACGGCCCCTTGAGCGACTACGTGCATGTCGAGGCC
AATCCGGCCTATGCCCTGCACGCCGGAATCCCCAACGTGGTCGGGCAGAAGGTGCGGGAGATGGTGCCGGGCGAGGCCGA
CGGCTGGGTCGAGCTGTATGGCGGCGTCCTGCGCACCGGCGAGCCGATCCGCTTCGAGCGCGAACTGGTCGCCACCGGAC
GCTATCTGGAGCTTGCGGCGTTCCGCGTCGAGCCGGCCAGCCGCCGCCAGGTCGCGGTGCTGTTCCAGGACATCACCCCG
CGCAAGCGCGCCGAGGCGGCGCTGCAGGAGATCAACGACACCTTGGAGGCGCGCGTCGTCGCCGCACTGGCCGAGCGCAA
GCTGCTCGCCGACATCGTCGAGGGCACCAACGCCTTCGTACAGGTGGTGGATACCCAGTTCCGCCTGATCGCCGTGAACG
GCGCCGCCGTCCAGGAGTTCGGCCGCATCTTCGGCGTACATCCCAAAGTGGGCGACAACCTGCTGGACCTGTTCAAGGAC
CTGCCGGAGCATCAGGCGGCTGTCCGCGCCGTGTGGTCGCGCGCGCTTGAGGGCGAGGAGTTCGTCGAGATCGGCGAATT
CGGCGTCGCCGGTCGCGACCGCCGCTTCTACGAGCTGCGCTTTTCGGTGCTGCGCGACGCCCGGGGCGAACAGATCGGCG
CCTATCAGTTCGCCTATGACGTCACTGAGCGGTTGCGCGAGCAGGCTCGGTTGCGCGAGGCGGAGGAGGCGCTGCGTCAG
TCGCAGAAGATGGAGGCGGTGGGCCAGCTGACCGGCGGCATCGCGCACGACTTCAACAATCTGCTGACCGGGATCATGGG
CTCCCTGGAGATGCTGCAGACCCGCATGCGCCAGGGCCGCTTCACCGATGTCGACCGCTATGTCGCGGCGGCGCAAGGCG
CCTCGAAGCGCGCGGCCGCACTGACCCATCGTCTGCTCGCCTTCTCGCGCCGGCAGACGCTCGATCCCAAGCCGACCGAC
GTCAACCGGCTGGTCATGGGCATGGAGGAGCTGGTCCGCCGCACCGTCGGCCCGCAGATCCATCTGGAGGTCGTGACCGC
CGGCGGGCTCTGGCCGGCGCTGATCGATTCCTCGCAGCTCGAAAGCGCCCTGCTCAACCTCTGCATCAATGCGCGCGATG
CGATGCCCGAAGGCGGCCGCATCACGATCGAGACCGCGAACAAGTGGCTGGACGACCGCTCCGCGCGCGAACGCGACCTG
TTGCCCGGGCAGTACATCTCGCTGTGCGTGACAGACACCGGCACGGGCATGACCCCTGACGTGATCGAGCACGCCTTCGA
TCCGTTCTTCACGACCAAGCCGATCGGCCAGGGCACCGGCCTCGGGCTGTCGATGGTCTACGGCTTTGCACGGCAGTCGG
GTGGACAGGTGCGGATCTATTCCGAGGTCGGCCAGGGCACCACGATGTGTCTCTATTTCCCGCGCCATTATGTCGGCGAG
GCCGAGGCCACCGATCCCGCGCGAGGCAGCGCTGCGACGTCGGCCCGGACGGGGCAGACCATCCTCGTCGTCGATGACGA
GCCGACCGTGCGGATGCTGGTGATGGAGGTGCTGGACGAGCGCGGCTATGCGGTGATCGAGGCCAAGGACGGCCCGACCG
GCCTTGCCGCCCTGCAGTCCAATGTGCGGATCGACCTCCTGATTACCGATGTCGGCCTGCCCGGCGGCATGAACGGCCGC
CAGCTCGCGGACGCCGCGCGCGCGACACGACCGGATCTGAAGGTGCTGTTCATCACCGGCTACGCCGAGAACGCGATCCT
CGGCAATGGCCAACTGGCGCCGGGAATGCAGGTGCTGACCAAGCCGTTCGACGTCGAGGCGCTGGCCGGCCGCGTCACCG
AGATGATCGAGAGCTGA

Upstream 100 bases:

>100_bases
GCGGTCATTGACATGGTATGTTGTCAGCCGAACTCCACAGCGAGCTGAGCATGCCTTGTGACGATCCATCGATATCGAAA
CGCGACGAGGCCCTCAAAGC

Downstream 100 bases:

>100_bases
GGGACGGAGGATGTGGCGCAGCGGATCCCGTCGTCACCTCGCGACCGCAGGCTTCTGCCTGCTGACGACGCTGTCGGTGG
TCTCGGCGTCGGCAGCTCAG

Product: sensor histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 698; Mature: 697

Protein sequence:

>698_residues
MSSAEIDTLRRRLRELESENARLQARFAADAGKRAEAETALAESEERYRTLFNSIDEGFCIIEFFDGPHGPLSDYVHVEA
NPAYALHAGIPNVVGQKVREMVPGEADGWVELYGGVLRTGEPIRFERELVATGRYLELAAFRVEPASRRQVAVLFQDITP
RKRAEAALQEINDTLEARVVAALAERKLLADIVEGTNAFVQVVDTQFRLIAVNGAAVQEFGRIFGVHPKVGDNLLDLFKD
LPEHQAAVRAVWSRALEGEEFVEIGEFGVAGRDRRFYELRFSVLRDARGEQIGAYQFAYDVTERLREQARLREAEEALRQ
SQKMEAVGQLTGGIAHDFNNLLTGIMGSLEMLQTRMRQGRFTDVDRYVAAAQGASKRAAALTHRLLAFSRRQTLDPKPTD
VNRLVMGMEELVRRTVGPQIHLEVVTAGGLWPALIDSSQLESALLNLCINARDAMPEGGRITIETANKWLDDRSARERDL
LPGQYISLCVTDTGTGMTPDVIEHAFDPFFTTKPIGQGTGLGLSMVYGFARQSGGQVRIYSEVGQGTTMCLYFPRHYVGE
AEATDPARGSAATSARTGQTILVVDDEPTVRMLVMEVLDERGYAVIEAKDGPTGLAALQSNVRIDLLITDVGLPGGMNGR
QLADAARATRPDLKVLFITGYAENAILGNGQLAPGMQVLTKPFDVEALAGRVTEMIES

Sequences:

>Translated_698_residues
MSSAEIDTLRRRLRELESENARLQARFAADAGKRAEAETALAESEERYRTLFNSIDEGFCIIEFFDGPHGPLSDYVHVEA
NPAYALHAGIPNVVGQKVREMVPGEADGWVELYGGVLRTGEPIRFERELVATGRYLELAAFRVEPASRRQVAVLFQDITP
RKRAEAALQEINDTLEARVVAALAERKLLADIVEGTNAFVQVVDTQFRLIAVNGAAVQEFGRIFGVHPKVGDNLLDLFKD
LPEHQAAVRAVWSRALEGEEFVEIGEFGVAGRDRRFYELRFSVLRDARGEQIGAYQFAYDVTERLREQARLREAEEALRQ
SQKMEAVGQLTGGIAHDFNNLLTGIMGSLEMLQTRMRQGRFTDVDRYVAAAQGASKRAAALTHRLLAFSRRQTLDPKPTD
VNRLVMGMEELVRRTVGPQIHLEVVTAGGLWPALIDSSQLESALLNLCINARDAMPEGGRITIETANKWLDDRSARERDL
LPGQYISLCVTDTGTGMTPDVIEHAFDPFFTTKPIGQGTGLGLSMVYGFARQSGGQVRIYSEVGQGTTMCLYFPRHYVGE
AEATDPARGSAATSARTGQTILVVDDEPTVRMLVMEVLDERGYAVIEAKDGPTGLAALQSNVRIDLLITDVGLPGGMNGR
QLADAARATRPDLKVLFITGYAENAILGNGQLAPGMQVLTKPFDVEALAGRVTEMIES
>Mature_697_residues
SSAEIDTLRRRLRELESENARLQARFAADAGKRAEAETALAESEERYRTLFNSIDEGFCIIEFFDGPHGPLSDYVHVEAN
PAYALHAGIPNVVGQKVREMVPGEADGWVELYGGVLRTGEPIRFERELVATGRYLELAAFRVEPASRRQVAVLFQDITPR
KRAEAALQEINDTLEARVVAALAERKLLADIVEGTNAFVQVVDTQFRLIAVNGAAVQEFGRIFGVHPKVGDNLLDLFKDL
PEHQAAVRAVWSRALEGEEFVEIGEFGVAGRDRRFYELRFSVLRDARGEQIGAYQFAYDVTERLREQARLREAEEALRQS
QKMEAVGQLTGGIAHDFNNLLTGIMGSLEMLQTRMRQGRFTDVDRYVAAAQGASKRAAALTHRLLAFSRRQTLDPKPTDV
NRLVMGMEELVRRTVGPQIHLEVVTAGGLWPALIDSSQLESALLNLCINARDAMPEGGRITIETANKWLDDRSARERDLL
PGQYISLCVTDTGTGMTPDVIEHAFDPFFTTKPIGQGTGLGLSMVYGFARQSGGQVRIYSEVGQGTTMCLYFPRHYVGEA
EATDPARGSAATSARTGQTILVVDDEPTVRMLVMEVLDERGYAVIEAKDGPTGLAALQSNVRIDLLITDVGLPGGMNGRQ
LADAARATRPDLKVLFITGYAENAILGNGQLAPGMQVLTKPFDVEALAGRVTEMIES

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=378, Percent_Identity=28.8359788359788, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1790436, Length=241, Percent_Identity=26.9709543568465, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1788713, Length=264, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI48994928, Length=448, Percent_Identity=24.3303571428571, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI145693157, Length=274, Percent_Identity=25.1824817518248, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76739; Mature: 76608

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAEIDTLRRRLRELESENARLQARFAADAGKRAEAETALAESEERYRTLFNSIDEGFC
CCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
IIEFFDGPHGPLSDYVHVEANPAYALHAGIPNVVGQKVREMVPGEADGWVELYGGVLRTG
EEEECCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHCCHHCCC
EPIRFERELVATGRYLELAAFRVEPASRRQVAVLFQDITPRKRAEAALQEINDTLEARVV
CCCEEHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AALAERKLLADIVEGTNAFVQVVDTQFRLIAVNGAAVQEFGRIFGVHPKVGDNLLDLFKD
HHHHHHHHHHHHHHCCHHHEEEECCCEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHH
LPEHQAAVRAVWSRALEGEEFVEIGEFGVAGRDRRFYELRFSVLRDARGEQIGAYQFAYD
CCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
VTERLREQARLREAEEALRQSQKMEAVGQLTGGIAHDFNNLLTGIMGSLEMLQTRMRQGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FTDVDRYVAAAQGASKRAAALTHRLLAFSRRQTLDPKPTDVNRLVMGMEELVRRTVGPQI
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
HLEVVTAGGLWPALIDSSQLESALLNLCINARDAMPEGGRITIETANKWLDDRSARERDL
EEEEEECCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHCCCCCHHHCC
LPGQYISLCVTDTGTGMTPDVIEHAFDPFFTTKPIGQGTGLGLSMVYGFARQSGGQVRIY
CCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEE
SEVGQGTTMCLYFPRHYVGEAEATDPARGSAATSARTGQTILVVDDEPTVRMLVMEVLDE
EECCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHC
RGYAVIEAKDGPTGLAALQSNVRIDLLITDVGLPGGMNGRQLADAARATRPDLKVLFITG
CCCEEEECCCCCCHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEEC
YAENAILGNGQLAPGMQVLTKPFDVEALAGRVTEMIES
CCCCEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSAEIDTLRRRLRELESENARLQARFAADAGKRAEAETALAESEERYRTLFNSIDEGFC
CCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
IIEFFDGPHGPLSDYVHVEANPAYALHAGIPNVVGQKVREMVPGEADGWVELYGGVLRTG
EEEECCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHCCHHCCC
EPIRFERELVATGRYLELAAFRVEPASRRQVAVLFQDITPRKRAEAALQEINDTLEARVV
CCCEEHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AALAERKLLADIVEGTNAFVQVVDTQFRLIAVNGAAVQEFGRIFGVHPKVGDNLLDLFKD
HHHHHHHHHHHHHHCCHHHEEEECCCEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHH
LPEHQAAVRAVWSRALEGEEFVEIGEFGVAGRDRRFYELRFSVLRDARGEQIGAYQFAYD
CCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
VTERLREQARLREAEEALRQSQKMEAVGQLTGGIAHDFNNLLTGIMGSLEMLQTRMRQGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FTDVDRYVAAAQGASKRAAALTHRLLAFSRRQTLDPKPTDVNRLVMGMEELVRRTVGPQI
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
HLEVVTAGGLWPALIDSSQLESALLNLCINARDAMPEGGRITIETANKWLDDRSARERDL
EEEEEECCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHCCCCCHHHCC
LPGQYISLCVTDTGTGMTPDVIEHAFDPFFTTKPIGQGTGLGLSMVYGFARQSGGQVRIY
CCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEE
SEVGQGTTMCLYFPRHYVGEAEATDPARGSAATSARTGQTILVVDDEPTVRMLVMEVLDE
EECCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHC
RGYAVIEAKDGPTGLAALQSNVRIDLLITDVGLPGGMNGRQLADAARATRPDLKVLFITG
CCCEEEECCCCCCHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEEC
YAENAILGNGQLAPGMQVLTKPFDVEALAGRVTEMIES
CCCCEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA