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The map label for this gene is cfa [H]

Identifier: 146340281

GI number: 146340281

Start: 3499523

End: 3500782

Strand: Reverse

Name: cfa [H]

Synonym: BRADO3304

Alternate gene names: 146340281

Gene position: 3500782-3499523 (Counterclockwise)

Preceding gene: 146340283

Following gene: 146340280

Centisome position: 46.95

GC content: 63.97

Gene sequence:

>1260_bases
GTGATGGGAATGGACCGTTTGCTGCGTAGTCTGTTGAGTCGTTTCATCTGCCGTGGGTCGATCAGCTTCACGACCGCCGA
CGGTGCCAAGTTCAACTGCGGGGACGGAACCGGTATCCCCGTCGCGGCCCGTTTCATGACCCGGGAGGCCGAGCGCCGCC
TCCTGACCAATCCGGAGCTTGCCCTCGGTGAAGCGTATATGGACGGCACATTCGTCCTCGAGCGCGGATCGATTGCCGAC
CTGCTCTCGATCATCATGAGCCAGCCGGCCGTGATGCCGGACTGGGCCAAGCCGCAATGGTGGCTGCGCTATCTGATCCG
GCCGCTGCGCCAGCTCAACATCAAGGCACGCGCGCGCCAAAACGTTGCGCATCACTACGACCTCGACGGGCGGCTCTACT
CGCTGTTTCTTGATGCCGACAAGCAATATTCCTGCGCCTATTTCGGCACGCCGGACACATCGCTCGACGACGCTCAGCTC
GCCAAGAAGCGGCACCTCGCCGCCAAGCTGCTGATCGATCCGGACGACCGCATCCTGGACATCGGCTGCGGCTGGGGCGG
GCTCGGACTTTATCTGGCGGAATTGACCGGCGCCGACGTCACCGGCGTGACCCTGTCGACCGAGCAGCTGCACGTCGCCA
ACGCGCGCGCGGCGGAGCGAAACCTCTCGGCGTCCGCCCGCTTCTTGCTGCAGGACTATCGCGACGTTCCCGGCACGTTC
GACCGCATCGTATCGGTCGGCATGTTCGAACATGTCGGCGTGAGGTTCTACGACACCTTCTTCCGCCACTGCGCAGAGTT
GCTCAAGGACGACGGCGTGATGGTGCTGCATTCGATCGGCCGCTCCGAGGGGCCGGATTCGACCAATCCGTGGATCGCCA
AATACATCTTTCCCGGCGGCTACATCCCCGCGCTGTCCGAGGTGCTGCCGGCGATCGAGCGCGCCGGGCTGCTGGTCTGC
GACATCGAGATCCTGCGTTTGCATTACGCGGAGACGCTGAAGGCGTGGCGCGAGCGCTTCATGGCCCGCCGCGAGGAAGC
CGTGCAGCTTTACGACGAGCGCTTCGCGCGGATGTGGGAGTTCTATCTCGCGGCGTCCGAGATGGCCTTCCGCAAGCAGA
ACATGATGAATTTCCAGATCCAGCTGACCAAGCGCCAAGGTGTCGTGCCCATGACCCGGGACTACATCCACCGCGAGGAA
GCGCGCCTGCGCGCGCTGGAACGCGGATATCGTCCTACGCTGCGCATGGCGGGCGAGTAA

Upstream 100 bases:

>100_bases
CTAACTAACATACGTAAGGTTTGAAGGGGAACCAATCGGTTCTCCACGCGTCGAGTGCGACAGCCGGGCAAGTCAGCATC
TCACGGGGGTAGCTCGTTGG

Downstream 100 bases:

>100_bases
GCGGCTCGGCACCGCAGCGCCACAGCCGTCGTCCGGGTGAAAGCCGGGACCCATAACCACTGTCGGCTGTTGTGAGGTCC
GACTGGATCGGCATCCCGCT

Product: putative cyclopropane-fatty-acyl-phospholipid synthase (Cfa-like)

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MMGMDRLLRSLLSRFICRGSISFTTADGAKFNCGDGTGIPVAARFMTREAERRLLTNPELALGEAYMDGTFVLERGSIAD
LLSIIMSQPAVMPDWAKPQWWLRYLIRPLRQLNIKARARQNVAHHYDLDGRLYSLFLDADKQYSCAYFGTPDTSLDDAQL
AKKRHLAAKLLIDPDDRILDIGCGWGGLGLYLAELTGADVTGVTLSTEQLHVANARAAERNLSASARFLLQDYRDVPGTF
DRIVSVGMFEHVGVRFYDTFFRHCAELLKDDGVMVLHSIGRSEGPDSTNPWIAKYIFPGGYIPALSEVLPAIERAGLLVC
DIEILRLHYAETLKAWRERFMARREEAVQLYDERFARMWEFYLAASEMAFRKQNMMNFQIQLTKRQGVVPMTRDYIHREE
ARLRALERGYRPTLRMAGE

Sequences:

>Translated_419_residues
MMGMDRLLRSLLSRFICRGSISFTTADGAKFNCGDGTGIPVAARFMTREAERRLLTNPELALGEAYMDGTFVLERGSIAD
LLSIIMSQPAVMPDWAKPQWWLRYLIRPLRQLNIKARARQNVAHHYDLDGRLYSLFLDADKQYSCAYFGTPDTSLDDAQL
AKKRHLAAKLLIDPDDRILDIGCGWGGLGLYLAELTGADVTGVTLSTEQLHVANARAAERNLSASARFLLQDYRDVPGTF
DRIVSVGMFEHVGVRFYDTFFRHCAELLKDDGVMVLHSIGRSEGPDSTNPWIAKYIFPGGYIPALSEVLPAIERAGLLVC
DIEILRLHYAETLKAWRERFMARREEAVQLYDERFARMWEFYLAASEMAFRKQNMMNFQIQLTKRQGVVPMTRDYIHREE
ARLRALERGYRPTLRMAGE
>Mature_419_residues
MMGMDRLLRSLLSRFICRGSISFTTADGAKFNCGDGTGIPVAARFMTREAERRLLTNPELALGEAYMDGTFVLERGSIAD
LLSIIMSQPAVMPDWAKPQWWLRYLIRPLRQLNIKARARQNVAHHYDLDGRLYSLFLDADKQYSCAYFGTPDTSLDDAQL
AKKRHLAAKLLIDPDDRILDIGCGWGGLGLYLAELTGADVTGVTLSTEQLHVANARAAERNLSASARFLLQDYRDVPGTF
DRIVSVGMFEHVGVRFYDTFFRHCAELLKDDGVMVLHSIGRSEGPDSTNPWIAKYIFPGGYIPALSEVLPAIERAGLLVC
DIEILRLHYAETLKAWRERFMARREEAVQLYDERFARMWEFYLAASEMAFRKQNMMNFQIQLTKRQGVVPMTRDYIHREE
ARLRALERGYRPTLRMAGE

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=345, Percent_Identity=38.8405797101449, Blast_Score=218, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI133904226, Length=288, Percent_Identity=30.9027777777778, Blast_Score=144, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 47738; Mature: 47738

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGMDRLLRSLLSRFICRGSISFTTADGAKFNCGDGTGIPVAARFMTREAERRLLTNPEL
CCCHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCH
ALGEAYMDGTFVLERGSIADLLSIIMSQPAVMPDWAKPQWWLRYLIRPLRQLNIKARARQ
HHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
NVAHHYDLDGRLYSLFLDADKQYSCAYFGTPDTSLDDAQLAKKRHLAAKLLIDPDDRILD
CHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHEEEECCCCCEEE
IGCGWGGLGLYLAELTGADVTGVTLSTEQLHVANARAAERNLSASARFLLQDYRDVPGTF
ECCCCCHHHHHHHHHCCCCEEEEEEECCCEEHHHHHHHHHCCHHHHHHHHHHHHCCCCHH
DRIVSVGMFEHVGVRFYDTFFRHCAELLKDDGVMVLHSIGRSEGPDSTNPWIAKYIFPGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEEECCCC
YIPALSEVLPAIERAGLLVCDIEILRLHYAETLKAWRERFMARREEAVQLYDERFARMWE
CHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYLAASEMAFRKQNMMNFQIQLTKRQGVVPMTRDYIHREEARLRALERGYRPTLRMAGE
HHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMGMDRLLRSLLSRFICRGSISFTTADGAKFNCGDGTGIPVAARFMTREAERRLLTNPEL
CCCHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCH
ALGEAYMDGTFVLERGSIADLLSIIMSQPAVMPDWAKPQWWLRYLIRPLRQLNIKARARQ
HHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
NVAHHYDLDGRLYSLFLDADKQYSCAYFGTPDTSLDDAQLAKKRHLAAKLLIDPDDRILD
CHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHEEEECCCCCEEE
IGCGWGGLGLYLAELTGADVTGVTLSTEQLHVANARAAERNLSASARFLLQDYRDVPGTF
ECCCCCHHHHHHHHHCCCCEEEEEEECCCEEHHHHHHHHHCCHHHHHHHHHHHHCCCCHH
DRIVSVGMFEHVGVRFYDTFFRHCAELLKDDGVMVLHSIGRSEGPDSTNPWIAKYIFPGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEEECCCC
YIPALSEVLPAIERAGLLVCDIEILRLHYAETLKAWRERFMARREEAVQLYDERFARMWE
CHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYLAASEMAFRKQNMMNFQIQLTKRQGVVPMTRDYIHREEARLRALERGYRPTLRMAGE
HHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]