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The map label for this gene is yqeF [C]

Identifier: 146340101

GI number: 146340101

Start: 3307594

End: 3308796

Strand: Direct

Name: yqeF [C]

Synonym: BRADO3110

Alternate gene names: 146340101

Gene position: 3307594-3308796 (Clockwise)

Preceding gene: 146340100

Following gene: 146340103

Centisome position: 44.36

GC content: 67.41

Gene sequence:

>1203_bases
TTGGGGGACAGGGAGACATTCGGGAGAGACAGCATGACCGCCAGCATCGTCGGATGGGCGCATACGCCGTTCGGAAAGTT
CGACGCCGAGACCGTCGAGAGCCTCGTCGTCAAGGTCGCCAATGAGGCGCTGGCGGATGCCGGCATTGCGGCCGGCGACG
TCGACGAGATCGTGCTCGGCCATTTCAATGCCGGCTTCTCGCCCCAGGACTTCACCGCCTCGCTGGTGCTGCAGGCCGAT
CCGGCGCTGCGCTTCAAGCCGGCGACGCGGGTCGAGAACGCCTGCGCCACCGGTTCTGCTGCCGTCCACCAGGGCATCCG
CGCCATCGCGGCCGGTGCCGCGAAGATCGTCCTCGTCGTCGGCGTCGAGCAGATGACGCGGACGCCGGGTCCGGAGATCG
GCAAGAACCTGCTGAAAGCCTCCTACCTGCCGGAGGACGGCGACACCGTCGGCGGCTTCGCCGGCGTGTTCGGCAAGATC
GCGCAGGGCTATTTCCAGAAATATGGCGACCAGTCCGATGCGCTGGCGCTGATCGCCGCCAAGAACCACAAGAACGGCGT
CGCCAACCCGTTCGCGCAGATGCGCAAGGATTTCGGCTTCGAGTTCTGCCGCTCCGAGAGCGAGAAGAACCCGTACGTCG
CCGGCCCCCTGAAGCGCACGGACTGCTCGCTGGTCTCCGACGGCGCCGCCGCGCTGGTGTTGACCGACAGCGAGACCGCC
AAGAAATTCGCCAAGGCGGTGAACGTCCGCGCGACCGCGCATGCGCAGGACTTCCTGCCGATGAGCAAGCGCGACATCCT
CGCCTTCGAGGGCTGCACGGTGGCCTGGCAGCGTGCGCTGGAGAAGGCCGGCGTCACGCTGTCCGATCTCTCCTTCGTCG
AGACCCATGACTGCTTCACCGTCGCCGAGCTGATCGAGTACGAGGCGATGGGCCTCACGCCCAGGGGGCAGGGTGCCCGC
GCCATCAAGGAAGGCTGGACGCTCAAGGACGGCAAGCTGCCGGTCAATCCCTCCGGCGGCCTCAAGGCCAAGGGCCACCC
GATCGGCGCCACCGGCGTCTCGATGCACGTGATGACCGCCATGCAGCTCACCGGCACGGCGCCCGAGGGCATGCAGCTCC
CCAACGCCAAGCTCGGCGGCATCTTCAACATGGGCGGCGCCGCGGTGGCGAACTACGTCTCGATCCTGGAGCCGGCGAAG
TAG

Upstream 100 bases:

>100_bases
CGACGATATCATCCGGATCCACATCGAGGACGAGCTCGGCGGCAAGTTCGTGGCCTGAGACCGCCACCAGCCTCTGGACT
CGCATGGAGCAAAGCGCCAT

Downstream 100 bases:

>100_bases
CGCCGGCTCTCTCCCCCGTCATTGCGAGCGAAGCGACGCAATCCAGGGCCGCACGTGCCGCCCTGGATTGGTGGTTGCAT
TGAGGGTCGTCGGAGCGAGC

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MGDRETFGRDSMTASIVGWAHTPFGKFDAETVESLVVKVANEALADAGIAAGDVDEIVLGHFNAGFSPQDFTASLVLQAD
PALRFKPATRVENACATGSAAVHQGIRAIAAGAAKIVLVVGVEQMTRTPGPEIGKNLLKASYLPEDGDTVGGFAGVFGKI
AQGYFQKYGDQSDALALIAAKNHKNGVANPFAQMRKDFGFEFCRSESEKNPYVAGPLKRTDCSLVSDGAAALVLTDSETA
KKFAKAVNVRATAHAQDFLPMSKRDILAFEGCTVAWQRALEKAGVTLSDLSFVETHDCFTVAELIEYEAMGLTPRGQGAR
AIKEGWTLKDGKLPVNPSGGLKAKGHPIGATGVSMHVMTAMQLTGTAPEGMQLPNAKLGGIFNMGGAAVANYVSILEPAK

Sequences:

>Translated_400_residues
MGDRETFGRDSMTASIVGWAHTPFGKFDAETVESLVVKVANEALADAGIAAGDVDEIVLGHFNAGFSPQDFTASLVLQAD
PALRFKPATRVENACATGSAAVHQGIRAIAAGAAKIVLVVGVEQMTRTPGPEIGKNLLKASYLPEDGDTVGGFAGVFGKI
AQGYFQKYGDQSDALALIAAKNHKNGVANPFAQMRKDFGFEFCRSESEKNPYVAGPLKRTDCSLVSDGAAALVLTDSETA
KKFAKAVNVRATAHAQDFLPMSKRDILAFEGCTVAWQRALEKAGVTLSDLSFVETHDCFTVAELIEYEAMGLTPRGQGAR
AIKEGWTLKDGKLPVNPSGGLKAKGHPIGATGVSMHVMTAMQLTGTAPEGMQLPNAKLGGIFNMGGAAVANYVSILEPAK
>Mature_399_residues
GDRETFGRDSMTASIVGWAHTPFGKFDAETVESLVVKVANEALADAGIAAGDVDEIVLGHFNAGFSPQDFTASLVLQADP
ALRFKPATRVENACATGSAAVHQGIRAIAAGAAKIVLVVGVEQMTRTPGPEIGKNLLKASYLPEDGDTVGGFAGVFGKIA
QGYFQKYGDQSDALALIAAKNHKNGVANPFAQMRKDFGFEFCRSESEKNPYVAGPLKRTDCSLVSDGAAALVLTDSETAK
KFAKAVNVRATAHAQDFLPMSKRDILAFEGCTVAWQRALEKAGVTLSDLSFVETHDCFTVAELIEYEAMGLTPRGQGARA
IKEGWTLKDGKLPVNPSGGLKAKGHPIGATGVSMHVMTAMQLTGTAPEGMQLPNAKLGGIFNMGGAAVANYVSILEPAK

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=399, Percent_Identity=33.0827067669173, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI302344760, Length=323, Percent_Identity=34.984520123839, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI302344767, Length=323, Percent_Identity=34.984520123839, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI302344762, Length=310, Percent_Identity=34.1935483870968, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI55956775, Length=272, Percent_Identity=34.1911764705882, Blast_Score=126, Evalue=4e-29,
Organism=Escherichia coli, GI87082165, Length=387, Percent_Identity=27.390180878553, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537653, Length=386, Percent_Identity=30.8290155440415, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24585051, Length=377, Percent_Identity=33.6870026525199, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI19921506, Length=366, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 41994; Mature: 41863

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDRETFGRDSMTASIVGWAHTPFGKFDAETVESLVVKVANEALADAGIAAGDVDEIVLG
CCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHC
HFNAGFSPQDFTASLVLQADPALRFKPATRVENACATGSAAVHQGIRAIAAGAAKIVLVV
CCCCCCCCCCCEEEEEEECCCCCEECCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEE
GVEQMTRTPGPEIGKNLLKASYLPEDGDTVGGFAGVFGKIAQGYFQKYGDQSDALALIAA
EHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
KNHKNGVANPFAQMRKDFGFEFCRSESEKNPYVAGPLKRTDCSLVSDGAAALVLTDSETA
CCCCCCCCCHHHHHHHHHCHHHHHCCCCCCCEEECCCCCCCCCEECCCCEEEEEECCHHH
KKFAKAVNVRATAHAQDFLPMSKRDILAFEGCTVAWQRALEKAGVTLSDLSFVETHDCFT
HHHHHHHCCCEEHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHCCHHHHHHHHH
VAELIEYEAMGLTPRGQGARAIKEGWTLKDGKLPVNPSGGLKAKGHPIGATGVSMHVMTA
HHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
MQLTGTAPEGMQLPNAKLGGIFNMGGAAVANYVSILEPAK
HHHCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GDRETFGRDSMTASIVGWAHTPFGKFDAETVESLVVKVANEALADAGIAAGDVDEIVLG
CCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHC
HFNAGFSPQDFTASLVLQADPALRFKPATRVENACATGSAAVHQGIRAIAAGAAKIVLVV
CCCCCCCCCCCEEEEEEECCCCCEECCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEE
GVEQMTRTPGPEIGKNLLKASYLPEDGDTVGGFAGVFGKIAQGYFQKYGDQSDALALIAA
EHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
KNHKNGVANPFAQMRKDFGFEFCRSESEKNPYVAGPLKRTDCSLVSDGAAALVLTDSETA
CCCCCCCCCHHHHHHHHHCHHHHHCCCCCCCEEECCCCCCCCCEECCCCEEEEEECCHHH
KKFAKAVNVRATAHAQDFLPMSKRDILAFEGCTVAWQRALEKAGVTLSDLSFVETHDCFT
HHHHHHHCCCEEHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHCCHHHHHHHHH
VAELIEYEAMGLTPRGQGARAIKEGWTLKDGKLPVNPSGGLKAKGHPIGATGVSMHVMTA
HHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
MQLTGTAPEGMQLPNAKLGGIFNMGGAAVANYVSILEPAK
HHHCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]