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The map label for this gene is mtaD [H]

Identifier: 146340090

GI number: 146340090

Start: 3294563

End: 3296101

Strand: Direct

Name: mtaD [H]

Synonym: BRADO3099

Alternate gene names: 146340090

Gene position: 3294563-3296101 (Clockwise)

Preceding gene: 146340089

Following gene: 146340091

Centisome position: 44.18

GC content: 65.11

Gene sequence:

>1539_bases
ATGGCAGAGGTTTTGGTCGGGGCGAAGTGGGTCGTCTCTGGAATTCAGGATCGGCATACGCCTGATGTGATCGAGGATGG
TGCCGTGCTCGCCCGCGAGGGTGTGATCGTCGCGGTCGGCCCGTTCGCCGAGCTGGAAAAGCTGGCGCCGCAGGCCAGCG
TGACGCGCCACCCGCACCATGTGATGCTACCGGGCTTCGTCAACAGCCACCACCATGTCGGGCTGACGCCGCTGCAGCTC
GGCTCTCCCGATCATGCGCTGGAATTGTGGTTCGCCAGCCGCCTTCCTGCGCGCCGTATCGACCTCTATCTCGACACGCT
GTATTCGGCGTTCGAGATGATCGCCTCCGGCGTCACCACCGTGCAGCATATCCATGGCTGGATGGCCGGCGGCTTCGACG
CGATCCACGTCGCCGCCACCAAGGTGCTCAAGGCCTATCGCGACATCGGGATGCGCGCGTCCTATTGCTACGCCGTGCGC
GAGCAGAACCGGCTGGTCTACGAGGCCGACGAAGAATTCTGCGCCCGGCTGCCGGCGCCATGGAACAAGCGGCTGGCGGC
GCATCTCAAGGCGCAGCAGGTGCCGTTCGCCGACTACATCAAGCTGTTCGACGTGCTCACGGCCGAGAACGCCGGCCAGA
GCCTGACCCGCATCCAGCTCGCGCCGGCGAATCTGCACTGGTGTACCGATGACGGACTGGTGGCGCTGCACGAGAAGTCG
CGCGCCGCCAAGGTGCCGATGCACATGCATCTGCTGGAGACCGCCTATCAGAAGGAATATGCGCGACGGCGCACCGGCAA
GACGGCGGTGCGTCATCTGCATGATCTCGGCGTGCTCGGCCCGCACATGACGCTCGGCCATGGCGTCTGGCTGACCGAGG
AGGACATCGACATCGTCGCCCACACCGGCACCTGCATCTGCCACAATTGCTCGTCCAACTTCCGGCTGCGCTCGGGGCTG
GCGCCGCTCAATGTCTGGGAGAAGAAAGGGATCACCATCGGCATGGGGCTGGATGAAGCGGGGATCAACGAGGACCGCGA
CATGCTGCAGGAATTGAAACTGGCGTTGCGCGTCCATCGCACGCCCGGCATGGACGACGAGGTGCCGACGTCGCCGCAGA
TCGTGCGCATGGCGACCGAGGGCGGCGCCAAGACCACCGCGTTCGGCGAGAGCATCGGGAAACTGGAGCAGGGCCGGCTG
TTCGACGCGGTGCTGATTGACTGGAATGCGGCGATGTATCCGTTCCAGGACCCGGACATCCCGATGCTCGATGCTCTCGT
CCAGCGCGCCAAGTCGCAGCATGTGGCGGCCGTGTATGTCGGCGGCGACATCGTCTACGCCGAGGGCCGCTTCACCCGCA
TCAACCGCGACGAGGTGCTGGGCGAGATCGCCAGTATCCTGGCCAAGCCGCGCAGCGAGGAGGAGGTCGCCCGCCGCGAG
CTCGGTCTCGCGGTGTTCCCGCACGTCAAGCAGTTCTACGACGGTTATTTCGATGGCACCGCGCACACGCCATTCTATCG
GACATCGACGAAAGCGTAG

Upstream 100 bases:

>100_bases
GCGCTATCACGAATATCGCGACTATTTCACCGAGCTGCTCGCTGCCGAGGTCGACAAGGCCTTCGCCGAGCAGTCGGGCC
TGTGAGAGGGAGAACGACAG

Downstream 100 bases:

>100_bases
TGAGGTGATCACATACAGCCCGCTGTCGAGTGTGAGTGCGCGCACGGTCTATGCCGTGGATCTCGTGCACACTGCGTCCG
TTCGCTGGAGGAGTGCGGAC

Product: putative amidohydrolase family protein

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MAEVLVGAKWVVSGIQDRHTPDVIEDGAVLAREGVIVAVGPFAELEKLAPQASVTRHPHHVMLPGFVNSHHHVGLTPLQL
GSPDHALELWFASRLPARRIDLYLDTLYSAFEMIASGVTTVQHIHGWMAGGFDAIHVAATKVLKAYRDIGMRASYCYAVR
EQNRLVYEADEEFCARLPAPWNKRLAAHLKAQQVPFADYIKLFDVLTAENAGQSLTRIQLAPANLHWCTDDGLVALHEKS
RAAKVPMHMHLLETAYQKEYARRRTGKTAVRHLHDLGVLGPHMTLGHGVWLTEEDIDIVAHTGTCICHNCSSNFRLRSGL
APLNVWEKKGITIGMGLDEAGINEDRDMLQELKLALRVHRTPGMDDEVPTSPQIVRMATEGGAKTTAFGESIGKLEQGRL
FDAVLIDWNAAMYPFQDPDIPMLDALVQRAKSQHVAAVYVGGDIVYAEGRFTRINRDEVLGEIASILAKPRSEEEVARRE
LGLAVFPHVKQFYDGYFDGTAHTPFYRTSTKA

Sequences:

>Translated_512_residues
MAEVLVGAKWVVSGIQDRHTPDVIEDGAVLAREGVIVAVGPFAELEKLAPQASVTRHPHHVMLPGFVNSHHHVGLTPLQL
GSPDHALELWFASRLPARRIDLYLDTLYSAFEMIASGVTTVQHIHGWMAGGFDAIHVAATKVLKAYRDIGMRASYCYAVR
EQNRLVYEADEEFCARLPAPWNKRLAAHLKAQQVPFADYIKLFDVLTAENAGQSLTRIQLAPANLHWCTDDGLVALHEKS
RAAKVPMHMHLLETAYQKEYARRRTGKTAVRHLHDLGVLGPHMTLGHGVWLTEEDIDIVAHTGTCICHNCSSNFRLRSGL
APLNVWEKKGITIGMGLDEAGINEDRDMLQELKLALRVHRTPGMDDEVPTSPQIVRMATEGGAKTTAFGESIGKLEQGRL
FDAVLIDWNAAMYPFQDPDIPMLDALVQRAKSQHVAAVYVGGDIVYAEGRFTRINRDEVLGEIASILAKPRSEEEVARRE
LGLAVFPHVKQFYDGYFDGTAHTPFYRTSTKA
>Mature_511_residues
AEVLVGAKWVVSGIQDRHTPDVIEDGAVLAREGVIVAVGPFAELEKLAPQASVTRHPHHVMLPGFVNSHHHVGLTPLQLG
SPDHALELWFASRLPARRIDLYLDTLYSAFEMIASGVTTVQHIHGWMAGGFDAIHVAATKVLKAYRDIGMRASYCYAVRE
QNRLVYEADEEFCARLPAPWNKRLAAHLKAQQVPFADYIKLFDVLTAENAGQSLTRIQLAPANLHWCTDDGLVALHEKSR
AAKVPMHMHLLETAYQKEYARRRTGKTAVRHLHDLGVLGPHMTLGHGVWLTEEDIDIVAHTGTCICHNCSSNFRLRSGLA
PLNVWEKKGITIGMGLDEAGINEDRDMLQELKLALRVHRTPGMDDEVPTSPQIVRMATEGGAKTTAFGESIGKLEQGRLF
DAVLIDWNAAMYPFQDPDIPMLDALVQRAKSQHVAAVYVGGDIVYAEGRFTRINRDEVLGEIASILAKPRSEEEVARREL
GLAVFPHVKQFYDGYFDGTAHTPFYRTSTKA

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=449, Percent_Identity=22.9398663697105, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI87082177, Length=444, Percent_Identity=24.5495495495495, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 56817; Mature: 56685

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVLVGAKWVVSGIQDRHTPDVIEDGAVLAREGVIVAVGPFAELEKLAPQASVTRHPHH
CCCEEECHHHHHHCCCCCCCCCHHHCCCEEEECCEEEEECCHHHHHHHCCCCCCCCCCCE
VMLPGFVNSHHHVGLTPLQLGSPDHALELWFASRLPARRIDLYLDTLYSAFEMIASGVTT
EEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VQHIHGWMAGGFDAIHVAATKVLKAYRDIGMRASYCYAVREQNRLVYEADEEFCARLPAP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEHHCCCEEEECCHHHHHHCCCC
WNKRLAAHLKAQQVPFADYIKLFDVLTAENAGQSLTRIQLAPANLHWCTDDGLVALHEKS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCEEEEECCC
RAAKVPMHMHLLETAYQKEYARRRTGKTAVRHLHDLGVLGPHMTLGHGVWLTEEDIDIVA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEECCCCEEEE
HTGTCICHNCSSNFRLRSGLAPLNVWEKKGITIGMGLDEAGINEDRDMLQELKLALRVHR
ECCEEEEECCCCCCEEECCCCCCCHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
TPGMDDEVPTSPQIVRMATEGGAKTTAFGESIGKLEQGRLFDAVLIDWNAAMYPFQDPDI
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCHHCCCEEEEEEEECCCEECCCCCCCC
PMLDALVQRAKSQHVAAVYVGGDIVYAEGRFTRINRDEVLGEIASILAKPRSEEEVARRE
HHHHHHHHHHCCCCEEEEEECCEEEEECCCEEECCHHHHHHHHHHHHCCCCCHHHHHHHH
LGLAVFPHVKQFYDGYFDGTAHTPFYRTSTKA
CCCHHHHHHHHHHCCCCCCCCCCCEECCCCCC
>Mature Secondary Structure 
AEVLVGAKWVVSGIQDRHTPDVIEDGAVLAREGVIVAVGPFAELEKLAPQASVTRHPHH
CCEEECHHHHHHCCCCCCCCCHHHCCCEEEECCEEEEECCHHHHHHHCCCCCCCCCCCE
VMLPGFVNSHHHVGLTPLQLGSPDHALELWFASRLPARRIDLYLDTLYSAFEMIASGVTT
EEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VQHIHGWMAGGFDAIHVAATKVLKAYRDIGMRASYCYAVREQNRLVYEADEEFCARLPAP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEHHCCCEEEECCHHHHHHCCCC
WNKRLAAHLKAQQVPFADYIKLFDVLTAENAGQSLTRIQLAPANLHWCTDDGLVALHEKS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCEEEEECCC
RAAKVPMHMHLLETAYQKEYARRRTGKTAVRHLHDLGVLGPHMTLGHGVWLTEEDIDIVA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEECCCCEEEE
HTGTCICHNCSSNFRLRSGLAPLNVWEKKGITIGMGLDEAGINEDRDMLQELKLALRVHR
ECCEEEEECCCCCCEEECCCCCCCHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
TPGMDDEVPTSPQIVRMATEGGAKTTAFGESIGKLEQGRLFDAVLIDWNAAMYPFQDPDI
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCHHCCCEEEEEEEECCCEECCCCCCCC
PMLDALVQRAKSQHVAAVYVGGDIVYAEGRFTRINRDEVLGEIASILAKPRSEEEVARRE
HHHHHHHHHHCCCCEEEEEECCEEEEECCCEEECCHHHHHHHHHHHHCCCCCHHHHHHHH
LGLAVFPHVKQFYDGYFDGTAHTPFYRTSTKA
CCCHHHHHHHHHHCCCCCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA