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The map label for this gene is yngJ [H]

Identifier: 146340028

GI number: 146340028

Start: 3234715

End: 3235950

Strand: Direct

Name: yngJ [H]

Synonym: BRADO3035

Alternate gene names: 146340028

Gene position: 3234715-3235950 (Clockwise)

Preceding gene: 146340025

Following gene: 146340029

Centisome position: 43.38

GC content: 64.97

Gene sequence:

>1236_bases
ATGGACTTCACGATGTCGGCGAAGCAGCAGGAATGGCTGGAGCGCGTGCGCAGCTTCATGACCAAGCATGTCCGCCCGGC
GGTGCCGATCTACAAGCAGCAGGACGCTGAGGGCGACCGCTGGAAGGTGATCCCGATCCTCGAGGACCTCAAGGCCAAGG
CGAAGGCCGAAGGCCTGTGGAACATGTTCATGCCGCCGTCGCCGCACGAGGACGACGAGTTTCGCGGCGCCGGCCTGACC
AATCTCGAATATGCGCTGCTGTCGGAGGAGATGGGCCGCATCTCCTGGGCCTCCGAGGTGTTCAACTGCTCGGCGCCCGA
CACCGGCAACATGGAGGTGTTCATCCGCTACGGCACCAAGGAGCAGAAGCGCAAATGGTTGCGCCCGCTGATGGACGGCG
AGATCCGCTCGGCGTTCCTGATGACCGAGCCGGCGGTGGCCTCGTCGGACGCCACCAACATCGAGACGCGCATTCAGCGA
GACGGCGATCACTACGTTATCAACGGCCGCAAATGGTGGTCGTCGGGCGTCGGCGATCCCCGCTGCAAGATCGCGATCCT
GATGGGCAAGACCGATCCGTCCGCCGCCAAGCATCAGCAGCAGTCGCAGATCCTGGTGCCGCTCGACACCCCCGGCATCA
AGGTCGAGAAGATGCTGCCGGTGTTCGGCTTCGACGACGCTCCGCACGGCCACGCCCAGGTGCTGCTCGAGAACGTGCGC
GTGCCGGCGGAGAACATCCTGCTCGGCGAGGGCCGCGGCTTCGAGATCGCTCAAGGGCGGCTCGGTCCGGGCCGCATCCA
TCACTGCATGCGCACCATCGGCAAGGCCGAGGAGTCGCTGGAGAAGATGGTGCGCCGGCTGATGACGCGCACTGCCTTCG
GCAAGAAGATCATCGAGCATTCGGTGTGGGAGCAGCGCATCGGCGAGGCCCGCACCAACATCGAGATGTGTCGGCTCTTG
TGCCTCAAGGCCGCCGACATGATGGACAAGGTCGGCAACAAGACCGCGCAGGGCGAGATCGCCATGATCAAGGTCGCCGC
TCCCAACATGGCGCTCAAGATCATCGACGACGCCATCCAGGCGTTCGGCGGCGCCGGTGTCTCGGATGATGCGGGTCTCG
CCAAGGACTACGCCAACATCCGCACGCTGCGTCTCGCCGACGGCCCCGACGAGGTGCACAACCGCGCCATCGCCCGGTTG
GAGATGAAGAAATACGCCAACGAGCCGCGGCACTGA

Upstream 100 bases:

>100_bases
CCGCGAATTCGAGCCGCGCAAGAACGCTCTTGCGCGGATGTGGTCGGCGGACCGACACTGTGGCCAAAACACGTTCGAGG
AAACGCTCAAGGAGAGTCCC

Downstream 100 bases:

>100_bases
GTGTAGTCTCGTAGGGTGGGCAAAGCGTCCGGCTGTGCGCGAAGCGCGCAGGCGGAGGCGTGCCCACCATTCGCGTTTGA
AGTAAGACGGTGGGCACGCT

Product: putative acyl-CoA dehydrogenase

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MDFTMSAKQQEWLERVRSFMTKHVRPAVPIYKQQDAEGDRWKVIPILEDLKAKAKAEGLWNMFMPPSPHEDDEFRGAGLT
NLEYALLSEEMGRISWASEVFNCSAPDTGNMEVFIRYGTKEQKRKWLRPLMDGEIRSAFLMTEPAVASSDATNIETRIQR
DGDHYVINGRKWWSSGVGDPRCKIAILMGKTDPSAAKHQQQSQILVPLDTPGIKVEKMLPVFGFDDAPHGHAQVLLENVR
VPAENILLGEGRGFEIAQGRLGPGRIHHCMRTIGKAEESLEKMVRRLMTRTAFGKKIIEHSVWEQRIGEARTNIEMCRLL
CLKAADMMDKVGNKTAQGEIAMIKVAAPNMALKIIDDAIQAFGGAGVSDDAGLAKDYANIRTLRLADGPDEVHNRAIARL
EMKKYANEPRH

Sequences:

>Translated_411_residues
MDFTMSAKQQEWLERVRSFMTKHVRPAVPIYKQQDAEGDRWKVIPILEDLKAKAKAEGLWNMFMPPSPHEDDEFRGAGLT
NLEYALLSEEMGRISWASEVFNCSAPDTGNMEVFIRYGTKEQKRKWLRPLMDGEIRSAFLMTEPAVASSDATNIETRIQR
DGDHYVINGRKWWSSGVGDPRCKIAILMGKTDPSAAKHQQQSQILVPLDTPGIKVEKMLPVFGFDDAPHGHAQVLLENVR
VPAENILLGEGRGFEIAQGRLGPGRIHHCMRTIGKAEESLEKMVRRLMTRTAFGKKIIEHSVWEQRIGEARTNIEMCRLL
CLKAADMMDKVGNKTAQGEIAMIKVAAPNMALKIIDDAIQAFGGAGVSDDAGLAKDYANIRTLRLADGPDEVHNRAIARL
EMKKYANEPRH
>Mature_411_residues
MDFTMSAKQQEWLERVRSFMTKHVRPAVPIYKQQDAEGDRWKVIPILEDLKAKAKAEGLWNMFMPPSPHEDDEFRGAGLT
NLEYALLSEEMGRISWASEVFNCSAPDTGNMEVFIRYGTKEQKRKWLRPLMDGEIRSAFLMTEPAVASSDATNIETRIQR
DGDHYVINGRKWWSSGVGDPRCKIAILMGKTDPSAAKHQQQSQILVPLDTPGIKVEKMLPVFGFDDAPHGHAQVLLENVR
VPAENILLGEGRGFEIAQGRLGPGRIHHCMRTIGKAEESLEKMVRRLMTRTAFGKKIIEHSVWEQRIGEARTNIEMCRLL
CLKAADMMDKVGNKTAQGEIAMIKVAAPNMALKIIDDAIQAFGGAGVSDDAGLAKDYANIRTLRLADGPDEVHNRAIARL
EMKKYANEPRH

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI211971008, Length=400, Percent_Identity=55.5, Blast_Score=460, Evalue=1e-129,
Organism=Homo sapiens, GI48976061, Length=400, Percent_Identity=55.5, Blast_Score=460, Evalue=1e-129,
Organism=Homo sapiens, GI38505218, Length=410, Percent_Identity=54.390243902439, Blast_Score=443, Evalue=1e-124,
Organism=Homo sapiens, GI187960098, Length=414, Percent_Identity=25.8454106280193, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI4557231, Length=414, Percent_Identity=25.8454106280193, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI4557233, Length=397, Percent_Identity=29.7229219143577, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI4501859, Length=329, Percent_Identity=27.9635258358663, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI226958412, Length=396, Percent_Identity=25.7575757575758, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI226958414, Length=328, Percent_Identity=27.1341463414634, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI21361497, Length=397, Percent_Identity=27.455919395466, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI7656849, Length=397, Percent_Identity=25.4408060453401, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI76496475, Length=344, Percent_Identity=27.906976744186, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI4557235, Length=344, Percent_Identity=27.906976744186, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4503943, Length=328, Percent_Identity=23.1707317073171, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4501857, Length=315, Percent_Identity=25.0793650793651, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI7669494, Length=309, Percent_Identity=23.6245954692557, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI87081958, Length=318, Percent_Identity=27.3584905660377, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786223, Length=405, Percent_Identity=22.962962962963, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=403, Percent_Identity=52.1091811414392, Blast_Score=405, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17534899, Length=414, Percent_Identity=27.536231884058, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17569725, Length=417, Percent_Identity=26.6187050359712, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71985184, Length=403, Percent_Identity=28.0397022332506, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17570075, Length=413, Percent_Identity=24.9394673123487, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17506239, Length=395, Percent_Identity=27.3417721518987, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17538396, Length=408, Percent_Identity=25, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=329, Percent_Identity=27.355623100304, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17551932, Length=330, Percent_Identity=24.2424242424242, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17505929, Length=333, Percent_Identity=23.7237237237237, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=329, Percent_Identity=26.4437689969605, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71985192, Length=350, Percent_Identity=26.8571428571429, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71990804, Length=256, Percent_Identity=29.296875, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=28.6324786324786, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71982178, Length=300, Percent_Identity=26, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17534353, Length=344, Percent_Identity=22.3837209302326, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666513, Length=336, Percent_Identity=29.7619047619048, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24660351, Length=406, Percent_Identity=26.8472906403941, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21356377, Length=336, Percent_Identity=30.6547619047619, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24646207, Length=338, Percent_Identity=30.7692307692308, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281363737, Length=336, Percent_Identity=27.9761904761905, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355753, Length=334, Percent_Identity=24.5508982035928, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19920834, Length=327, Percent_Identity=23.8532110091743, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 46130; Mature: 46130

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS00073 ACYL_COA_DH_2 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTMSAKQQEWLERVRSFMTKHVRPAVPIYKQQDAEGDRWKVIPILEDLKAKAKAEGLW
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCHH
NMFMPPSPHEDDEFRGAGLTNLEYALLSEEMGRISWASEVFNCSAPDTGNMEVFIRYGTK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCH
EQKRKWLRPLMDGEIRSAFLMTEPAVASSDATNIETRIQRDGDHYVINGRKWWSSGVGDP
HHHHHHHHHHHCCHHHHEEEEECCCCCCCCCCCHHHHEECCCCEEEECCCCHHCCCCCCC
RCKIAILMGKTDPSAAKHQQQSQILVPLDTPGIKVEKMLPVFGFDDAPHGHAQVLLENVR
CEEEEEEEECCCCHHHHHHHHCCEEEEECCCCCCHHHCCCEECCCCCCCHHHHHHHHHCC
VPAENILLGEGRGFEIAQGRLGPGRIHHCMRTIGKAEESLEKMVRRLMTRTAFGKKIIEH
CCHHHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVWEQRIGEARTNIEMCRLLCLKAADMMDKVGNKTAQGEIAMIKVAAPNMALKIIDDAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHH
AFGGAGVSDDAGLAKDYANIRTLRLADGPDEVHNRAIARLEMKKYANEPRH
HHCCCCCCCCCHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDFTMSAKQQEWLERVRSFMTKHVRPAVPIYKQQDAEGDRWKVIPILEDLKAKAKAEGLW
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCHH
NMFMPPSPHEDDEFRGAGLTNLEYALLSEEMGRISWASEVFNCSAPDTGNMEVFIRYGTK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCH
EQKRKWLRPLMDGEIRSAFLMTEPAVASSDATNIETRIQRDGDHYVINGRKWWSSGVGDP
HHHHHHHHHHHCCHHHHEEEEECCCCCCCCCCCHHHHEECCCCEEEECCCCHHCCCCCCC
RCKIAILMGKTDPSAAKHQQQSQILVPLDTPGIKVEKMLPVFGFDDAPHGHAQVLLENVR
CEEEEEEEECCCCHHHHHHHHCCEEEEECCCCCCHHHCCCEECCCCCCCHHHHHHHHHCC
VPAENILLGEGRGFEIAQGRLGPGRIHHCMRTIGKAEESLEKMVRRLMTRTAFGKKIIEH
CCHHHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVWEQRIGEARTNIEMCRLLCLKAADMMDKVGNKTAQGEIAMIKVAAPNMALKIIDDAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHH
AFGGAGVSDDAGLAKDYANIRTLRLADGPDEVHNRAIARLEMKKYANEPRH
HHCCCCCCCCCHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]