Click here to switch to the map view.

The map label for this gene is rcsC [C]

Identifier: 146339710

GI number: 146339710

Start: 2905872

End: 2907704

Strand: Direct

Name: rcsC [C]

Synonym: BRADO2708

Alternate gene names: 146339710

Gene position: 2905872-2907704 (Clockwise)

Preceding gene: 146339707

Following gene: 146339711

Centisome position: 38.97

GC content: 66.45

Gene sequence:

>1833_bases
GTGAGTGTGTTGAGTATCATCCGCGATTGTCTTGATGCTTTGCTGCATCCGTCGGCTCGAACTGATGCGATGACACGCGC
GCGCCATCGCGCTTTCATCGCGCCGCGCCTGCTCGGCAGCCTCGCCGCTTTTGCCGTGTTCCCGGCCTACCTCGCAATGC
GCGGCGCACCGAGTGCGCTCGAGGTCGGCGCGCTGGCCTGGCTGATCGCGCCAATTTTGTTGTCCTGGTATCTGTCGCGC
ACCGGCCGTTATGAGAGCGCCTGCGCGCTGTCGTCGCTGGCGCTGTCCGCATTGATCATGGCGGTGTCGATCGAGACCGG
AGGCATCGAATCCTTCGCGGCTGTCTGGCTGATCGTCGTCCCCCTCGAGGCATCATTTTCGGCCTCGCGCCGCGTCGTGG
TGTTCTCCGCAGCGCTCGCGCTGTCCTGCGCGCTGCTGCTGATTGTGATCGGCCATTGTGGCTGGCTGCCGAAGCCCGAG
ACCAATCCGGCGCTGCGCACGAGCCTGCTCGCCTTCGGCGTTGCCTCGGCGACGCTGTACGCGGCCGTGCTCGCCTTTGC
CGCCGACACCCTCGCGCGCACCAGCGTGACGCTGCTGTCGATGGAGGAGGAGCGCTATCGTCTGCTCGCGCGCAACATGA
GCGACGTGATTTCCCGCCATCGCCGCAACGGCGCTGTCATGTTCATTTCGCCCGCTGTGGAAACGCTGCTCGGCGCGCCG
GTTGCGCAGCTCCACGGCCACGGCCTGTTCGAGCGCGTGCATGTCGCGGATCGCCCGGCCTATCTGACCGCGCTGTCCGA
AGCGGCCGGCGGCAGCGAAGCCTCGAGCGTCGAGTTCCGCCTGCGCCGCGATGCGCCGGGCGAGGGCCGCGCTGGGCAGC
AGTCCGTCGATTTCATCTGGGTCGAGATGCGCTGCCGGCCGCTCGATCGCGCCGGAGTCACCTGCGCGGGCACCGATCAG
GAGGTGGTCGCGGTCATGCGCGACGTCACCGACCGCAAGCTGCAGGAGCAGGCGCTGGAGCTTGCGCGCAGCGCCGCGGA
ACGCGCCGACGCCGCCAAGACGCGATTCCTCGCGACCATGAGCCACGAGCTGCGTACGCCGCTGAATGCCATCATCGGCT
TCTCCGAGATGCTGATGCAGGAGCAGGTGCTCGTGCTCAACGCCGCGCGACGCCGCGAATATGCGCAGCTGATCAACGAT
TCCGGCCAGCATCTGCTGTCGGTCGTGAACGGCATCCTCGACATGTCGAAGATGGAGTCCGGCCATTTCGAGCTGACGCC
GGAGCCGTTTGCGCCGCGCACCGCGCTGTTCAATTGCTGCAATCTGCTGGCGCTGCGTGCGCGCGAGAACGGTGTCGATC
TGGCGGCGGATGCGCCGCATGACCTGCCTGTCATCACCGGCGATCCGCGCGCATTCAAGCAGATCGTGATCAACCTCGTC
TCCAATGCCATCAAGTTCACCGAGCGTGGCGGTCGTGTCACGGTGTCCGCCGGCGTCGACGGCGCGCGCCTGTTGTTGCG
AATCACCGACACGGGTGTCGGCATCGCGGCCGACGATCTCAAGCGCATCGGCGATCCGTTCTTCCAGGCCGGCAAGACCT
ATCAGCGCCGTCACGAGGGAACCGGACTTGGCCTGTCGATCGTCAAGAGTCTCGTGACCTTGCACGGCGGCGAAATGTCG
ATAGAAAGCAAGCTCGACGAGGGAACGACGGTCACGATCGCGCTGCCGATCAACTGCGTCGCGGAGATGGCCGCTGGTGC
CACCGTCACGCCGCTGTCGCCCGCGCGGTCCGCCCAGGCGGGGCAGGTGATGCAGGTGAAGAAGAGTGCCTAG

Upstream 100 bases:

>100_bases
GCGTTCGCTTAATGCGAGTCTGACACGGTGCTTCCGACGACAGGGGGCGTCCCGGCGCGTTCTTTGTGAGAACGAACCGA
CAGGCCGAGGCGCGAGAGCC

Downstream 100 bases:

>100_bases
ACGAGCTGCAGAGGATGATGAGGCGCCGCCGCGCCGTCGCAAGCGCACGGCTGCAACTGCTGCCGTGGTCGAAGTGGCGG
ACGAACGCGGCTGGCTGATG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MSVLSIIRDCLDALLHPSARTDAMTRARHRAFIAPRLLGSLAAFAVFPAYLAMRGAPSALEVGALAWLIAPILLSWYLSR
TGRYESACALSSLALSALIMAVSIETGGIESFAAVWLIVVPLEASFSASRRVVVFSAALALSCALLLIVIGHCGWLPKPE
TNPALRTSLLAFGVASATLYAAVLAFAADTLARTSVTLLSMEEERYRLLARNMSDVISRHRRNGAVMFISPAVETLLGAP
VAQLHGHGLFERVHVADRPAYLTALSEAAGGSEASSVEFRLRRDAPGEGRAGQQSVDFIWVEMRCRPLDRAGVTCAGTDQ
EVVAVMRDVTDRKLQEQALELARSAAERADAAKTRFLATMSHELRTPLNAIIGFSEMLMQEQVLVLNAARRREYAQLIND
SGQHLLSVVNGILDMSKMESGHFELTPEPFAPRTALFNCCNLLALRARENGVDLAADAPHDLPVITGDPRAFKQIVINLV
SNAIKFTERGGRVTVSAGVDGARLLLRITDTGVGIAADDLKRIGDPFFQAGKTYQRRHEGTGLGLSIVKSLVTLHGGEMS
IESKLDEGTTVTIALPINCVAEMAAGATVTPLSPARSAQAGQVMQVKKSA

Sequences:

>Translated_610_residues
MSVLSIIRDCLDALLHPSARTDAMTRARHRAFIAPRLLGSLAAFAVFPAYLAMRGAPSALEVGALAWLIAPILLSWYLSR
TGRYESACALSSLALSALIMAVSIETGGIESFAAVWLIVVPLEASFSASRRVVVFSAALALSCALLLIVIGHCGWLPKPE
TNPALRTSLLAFGVASATLYAAVLAFAADTLARTSVTLLSMEEERYRLLARNMSDVISRHRRNGAVMFISPAVETLLGAP
VAQLHGHGLFERVHVADRPAYLTALSEAAGGSEASSVEFRLRRDAPGEGRAGQQSVDFIWVEMRCRPLDRAGVTCAGTDQ
EVVAVMRDVTDRKLQEQALELARSAAERADAAKTRFLATMSHELRTPLNAIIGFSEMLMQEQVLVLNAARRREYAQLIND
SGQHLLSVVNGILDMSKMESGHFELTPEPFAPRTALFNCCNLLALRARENGVDLAADAPHDLPVITGDPRAFKQIVINLV
SNAIKFTERGGRVTVSAGVDGARLLLRITDTGVGIAADDLKRIGDPFFQAGKTYQRRHEGTGLGLSIVKSLVTLHGGEMS
IESKLDEGTTVTIALPINCVAEMAAGATVTPLSPARSAQAGQVMQVKKSA
>Mature_609_residues
SVLSIIRDCLDALLHPSARTDAMTRARHRAFIAPRLLGSLAAFAVFPAYLAMRGAPSALEVGALAWLIAPILLSWYLSRT
GRYESACALSSLALSALIMAVSIETGGIESFAAVWLIVVPLEASFSASRRVVVFSAALALSCALLLIVIGHCGWLPKPET
NPALRTSLLAFGVASATLYAAVLAFAADTLARTSVTLLSMEEERYRLLARNMSDVISRHRRNGAVMFISPAVETLLGAPV
AQLHGHGLFERVHVADRPAYLTALSEAAGGSEASSVEFRLRRDAPGEGRAGQQSVDFIWVEMRCRPLDRAGVTCAGTDQE
VVAVMRDVTDRKLQEQALELARSAAERADAAKTRFLATMSHELRTPLNAIIGFSEMLMQEQVLVLNAARRREYAQLINDS
GQHLLSVVNGILDMSKMESGHFELTPEPFAPRTALFNCCNLLALRARENGVDLAADAPHDLPVITGDPRAFKQIVINLVS
NAIKFTERGGRVTVSAGVDGARLLLRITDTGVGIAADDLKRIGDPFFQAGKTYQRRHEGTGLGLSIVKSLVTLHGGEMSI
ESKLDEGTTVTIALPINCVAEMAAGATVTPLSPARSAQAGQVMQVKKSA

Specific function: Member Of The Two-Component Regulatory System rcsC/rcsB Involved In The Regulation Of The Expression Of Genes Involved In Colanic Acid Capsule Synthesis. rcsC Probably Functions As A Membrane-Associated Protein Kinase That Phosphorylates rcsB In Response

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAC (PAS-associated C-terminal) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=39.2996108949416, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1789149, Length=276, Percent_Identity=35.8695652173913, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87081816, Length=301, Percent_Identity=35.5481727574751, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1788713, Length=295, Percent_Identity=33.5593220338983, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI48994928, Length=265, Percent_Identity=35.8490566037736, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=30.5676855895196, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786912, Length=250, Percent_Identity=29.6, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1786600, Length=273, Percent_Identity=28.2051282051282, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=28.1512605042017, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=26.0869565217391, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1788549, Length=376, Percent_Identity=24.2021276595745, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=26.9387755102041, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=246, Percent_Identity=28.0487804878049, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65383; Mature: 65252

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLSIIRDCLDALLHPSARTDAMTRARHRAFIAPRLLGSLAAFAVFPAYLAMRGAPSAL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EVGALAWLIAPILLSWYLSRTGRYESACALSSLALSALIMAVSIETGGIESFAAVWLIVV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEE
PLEASFSASRRVVVFSAALALSCALLLIVIGHCGWLPKPETNPALRTSLLAFGVASATLY
ECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AAVLAFAADTLARTSVTLLSMEEERYRLLARNMSDVISRHRRNGAVMFISPAVETLLGAP
HHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCC
VAQLHGHGLFERVHVADRPAYLTALSEAAGGSEASSVEFRLRRDAPGEGRAGQQSVDFIW
HHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEE
VEMRCRPLDRAGVTCAGTDQEVVAVMRDVTDRKLQEQALELARSAAERADAAKTRFLATM
EEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHELRTPLNAIIGFSEMLMQEQVLVLNAARRREYAQLINDSGQHLLSVVNGILDMSKMES
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
GHFELTPEPFAPRTALFNCCNLLALRARENGVDLAADAPHDLPVITGDPRAFKQIVINLV
CCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEEECCHHHHHHHHHHHH
SNAIKFTERGGRVTVSAGVDGARLLLRITDTGVGIAADDLKRIGDPFFQAGKTYQRRHEG
HHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCEEHHHHHHCCCHHHHCCHHHHHHHCC
TGLGLSIVKSLVTLHGGEMSIESKLDEGTTVTIALPINCVAEMAAGATVTPLSPARSAQA
CCCHHHHHHHHHHHCCCCEEHHHHCCCCCEEEEEECHHHHHHHHCCCEECCCCCCCCCCC
GQVMQVKKSA
CCHHHHHCCC
>Mature Secondary Structure 
SVLSIIRDCLDALLHPSARTDAMTRARHRAFIAPRLLGSLAAFAVFPAYLAMRGAPSAL
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EVGALAWLIAPILLSWYLSRTGRYESACALSSLALSALIMAVSIETGGIESFAAVWLIVV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEE
PLEASFSASRRVVVFSAALALSCALLLIVIGHCGWLPKPETNPALRTSLLAFGVASATLY
ECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AAVLAFAADTLARTSVTLLSMEEERYRLLARNMSDVISRHRRNGAVMFISPAVETLLGAP
HHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCC
VAQLHGHGLFERVHVADRPAYLTALSEAAGGSEASSVEFRLRRDAPGEGRAGQQSVDFIW
HHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEE
VEMRCRPLDRAGVTCAGTDQEVVAVMRDVTDRKLQEQALELARSAAERADAAKTRFLATM
EEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHELRTPLNAIIGFSEMLMQEQVLVLNAARRREYAQLINDSGQHLLSVVNGILDMSKMES
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
GHFELTPEPFAPRTALFNCCNLLALRARENGVDLAADAPHDLPVITGDPRAFKQIVINLV
CCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEEECCHHHHHHHHHHHH
SNAIKFTERGGRVTVSAGVDGARLLLRITDTGVGIAADDLKRIGDPFFQAGKTYQRRHEG
HHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCEEHHHHHHCCCHHHHCCHHHHHHHCC
TGLGLSIVKSLVTLHGGEMSIESKLDEGTTVTIALPINCVAEMAAGATVTPLSPARSAQA
CCCHHHHHHHHHHHCCCCEEHHHHCCCCCEEEEEECHHHHHHHHCCCEECCCCCCCCCCC
GQVMQVKKSA
CCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 7756693 [H]