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The map label for this gene is argD [H]

Identifier: 146339642

GI number: 146339642

Start: 2829436

End: 2830827

Strand: Direct

Name: argD [H]

Synonym: BRADO2635

Alternate gene names: 146339642

Gene position: 2829436-2830827 (Clockwise)

Preceding gene: 146339640

Following gene: 146339647

Centisome position: 37.95

GC content: 63.15

Gene sequence:

>1392_bases
ATGCTAAAGTCCAATCTAGACGTTTCCGAGATGTTTGTGGAGCGCCAGGCGCAGCGCAGCACCATGCATTCTCGGCATCT
GAACGAGCAGTTGGTCCGCGTTCTCAAGACGATTGGATATGATGTCGGGTTCCAAAAGGGCCAAGGGCAATATCTCTACG
ATCGTGACGGCGCCCGTTACCTCGATCTGCTGAGTGGCTTCGGCGTCTTTGCTATCGGACGCAACCATCCGACCCTTCGT
GACGCGCTGAAGAGCGTTCTCGACAGCGACCTGCCAAATCTTGTGCAGCTCGACGTCTCGACCCTGGCGGGAGTTCTTGC
CGAGCGCCTGCTGGAATATGTCCCTTATCTCGACAAGGTGTTCTTCGCCAATTCCGGCGCCGAGACGGTCGAGGCGGCGA
TCAAATTCGCGCGGGGTGCGACGGGGCGTCCGGGCATCGTCTATTGCGGGCATTCCTACCACGGCCTCACCTACGGTGCG
CTGTCGCTGACCGAGGACTCCAATTTCCGCACCGGCTTCGAGCCGCTGCTGCCGGGTTGCACGGCCGTTCCGTTCAACGA
TCTCGCGGCGCTCGAGCAGGCGCTGGCATCACGCGAAATTGCGGCCTTCATCGTCGAGCCGATTCAGGGCAAGGGCGTGA
ACATGCCCACCGACGAATTCCTGCCGGGCGCCGCCGCGCTCTGCAAGAAATACGGCTCGCTGTTCATCGCCGACGAGATC
CAGACCGGCATGGGGCGCACCGGGCGGTTCCTCGCCGTGGAACACTGGAACGTCGAGCCCGACATGGTGCTACTGTCGAA
GGCGCTGTCCGGCGGTCACGTGCCGGTCGGCGCGCTGCTGACGCGCAAGGCCATCTTCGACAAGATCTTCAACCGCATGG
ATCGTGCTGTCGTGCACGGCTCGACTTTCGCCAAGAACGACCTCGCGATGGCGGCGGGCATCGCCACGCTCGAGGTGCTC
AAGGCCGAGAAGCTGATCGAGGCCGCCGCCAAGCGCGGCGCCGAGCTGCGCCTGGCACTGACGCGCATGGTGCCCGGCTA
CGAGCTGCTCAAGGAGGTGCGCGGCAAGGGCCTGATGATCGGCGTCGAGTTCGGTCCGCCGAAATCGCTCCGTCTCAAGG
CGTCCTGGACCATGCTGGAGAGCGCCAATAAGGGCCTGTTCTGCCAGCTGATCACGGTGCCGCTGTTCAAGGATCACAAG
ATCCTGACCCAGGTCGCCGGCCACGGCCTGCACACCATCAAGCTGCTCCCACCGCTGACGATCACCGAAGACGACTGCAA
CTGGATCGAGCGGGCCTTCGACGACGTCATCGCCCAGAGCCACAAGGTCCCCGGCGCGATCTGGTCGCTCGGCAAGACCC
TGGTCGACAACGCGATCAGGAAGTCGGCCTAA

Upstream 100 bases:

>100_bases
GGCAGAAACCCGTGCTTGCTTTGATGGTGCGAATGAGGGCAAAACGCCGCATTGCGCGTTTTCAGTTGACGTCACGTCCA
TCAACCGAAGTATGTAGCCG

Downstream 100 bases:

>100_bases
GGTTCCTCGCCTCGGAAGGATAGGGAGGCACCTCTCTCGGCATACTCACTGTCATCGCCTGGCTCGACCGGGCGATCCAG
TATGCTGAGACGGTTGTGGT

Product: putative aminotransferase ornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MLKSNLDVSEMFVERQAQRSTMHSRHLNEQLVRVLKTIGYDVGFQKGQGQYLYDRDGARYLDLLSGFGVFAIGRNHPTLR
DALKSVLDSDLPNLVQLDVSTLAGVLAERLLEYVPYLDKVFFANSGAETVEAAIKFARGATGRPGIVYCGHSYHGLTYGA
LSLTEDSNFRTGFEPLLPGCTAVPFNDLAALEQALASREIAAFIVEPIQGKGVNMPTDEFLPGAAALCKKYGSLFIADEI
QTGMGRTGRFLAVEHWNVEPDMVLLSKALSGGHVPVGALLTRKAIFDKIFNRMDRAVVHGSTFAKNDLAMAAGIATLEVL
KAEKLIEAAAKRGAELRLALTRMVPGYELLKEVRGKGLMIGVEFGPPKSLRLKASWTMLESANKGLFCQLITVPLFKDHK
ILTQVAGHGLHTIKLLPPLTITEDDCNWIERAFDDVIAQSHKVPGAIWSLGKTLVDNAIRKSA

Sequences:

>Translated_463_residues
MLKSNLDVSEMFVERQAQRSTMHSRHLNEQLVRVLKTIGYDVGFQKGQGQYLYDRDGARYLDLLSGFGVFAIGRNHPTLR
DALKSVLDSDLPNLVQLDVSTLAGVLAERLLEYVPYLDKVFFANSGAETVEAAIKFARGATGRPGIVYCGHSYHGLTYGA
LSLTEDSNFRTGFEPLLPGCTAVPFNDLAALEQALASREIAAFIVEPIQGKGVNMPTDEFLPGAAALCKKYGSLFIADEI
QTGMGRTGRFLAVEHWNVEPDMVLLSKALSGGHVPVGALLTRKAIFDKIFNRMDRAVVHGSTFAKNDLAMAAGIATLEVL
KAEKLIEAAAKRGAELRLALTRMVPGYELLKEVRGKGLMIGVEFGPPKSLRLKASWTMLESANKGLFCQLITVPLFKDHK
ILTQVAGHGLHTIKLLPPLTITEDDCNWIERAFDDVIAQSHKVPGAIWSLGKTLVDNAIRKSA
>Mature_463_residues
MLKSNLDVSEMFVERQAQRSTMHSRHLNEQLVRVLKTIGYDVGFQKGQGQYLYDRDGARYLDLLSGFGVFAIGRNHPTLR
DALKSVLDSDLPNLVQLDVSTLAGVLAERLLEYVPYLDKVFFANSGAETVEAAIKFARGATGRPGIVYCGHSYHGLTYGA
LSLTEDSNFRTGFEPLLPGCTAVPFNDLAALEQALASREIAAFIVEPIQGKGVNMPTDEFLPGAAALCKKYGSLFIADEI
QTGMGRTGRFLAVEHWNVEPDMVLLSKALSGGHVPVGALLTRKAIFDKIFNRMDRAVVHGSTFAKNDLAMAAGIATLEVL
KAEKLIEAAAKRGAELRLALTRMVPGYELLKEVRGKGLMIGVEFGPPKSLRLKASWTMLESANKGLFCQLITVPLFKDHK
ILTQVAGHGLHTIKLLPPLTITEDDCNWIERAFDDVIAQSHKVPGAIWSLGKTLVDNAIRKSA

Specific function: Unknown

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=399, Percent_Identity=37.34335839599, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI284507298, Length=311, Percent_Identity=39.2282958199357, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI13994255, Length=441, Percent_Identity=27.437641723356, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI24119277, Length=420, Percent_Identity=26.6666666666667, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI37574042, Length=419, Percent_Identity=26.0143198090692, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=25.3588516746411, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI226442709, Length=357, Percent_Identity=25.7703081232493, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI188536080, Length=486, Percent_Identity=23.8683127572016, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI38679950, Length=486, Percent_Identity=23.8683127572016, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI38679946, Length=486, Percent_Identity=23.8683127572016, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI145693181, Length=454, Percent_Identity=33.7004405286344, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1789759, Length=335, Percent_Identity=33.134328358209, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1788044, Length=324, Percent_Identity=35.1851851851852, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787560, Length=412, Percent_Identity=29.6116504854369, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1786349, Length=335, Percent_Identity=34.9253731343284, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1789016, Length=332, Percent_Identity=30.1204819277108, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1786991, Length=349, Percent_Identity=32.6647564469914, Blast_Score=128, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=415, Percent_Identity=33.9759036144578, Blast_Score=204, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI25144274, Length=300, Percent_Identity=35, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI32564660, Length=451, Percent_Identity=30.1552106430155, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=428, Percent_Identity=27.803738317757, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=426, Percent_Identity=28.169014084507, Blast_Score=92, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323470, Length=409, Percent_Identity=32.518337408313, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6324432, Length=421, Percent_Identity=30.8788598574822, Blast_Score=156, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6324386, Length=327, Percent_Identity=26.9113149847095, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357415, Length=330, Percent_Identity=37.2727272727273, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=29.7052154195011, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28574759, Length=422, Percent_Identity=30.3317535545024, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI21356575, Length=421, Percent_Identity=26.3657957244656, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281366494, Length=403, Percent_Identity=26.5508684863524, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24667139, Length=403, Percent_Identity=26.5508684863524, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24667143, Length=403, Percent_Identity=26.5508684863524, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 50577; Mature: 50577

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSNLDVSEMFVERQAQRSTMHSRHLNEQLVRVLKTIGYDVGFQKGQGQYLYDRDGARY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHH
LDLLSGFGVFAIGRNHPTLRDALKSVLDSDLPNLVQLDVSTLAGVLAERLLEYVPYLDKV
HHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFANSGAETVEAAIKFARGATGRPGIVYCGHSYHGLTYGALSLTEDSNFRTGFEPLLPGC
HHCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCHHHCCCC
TAVPFNDLAALEQALASREIAAFIVEPIQGKGVNMPTDEFLPGAAALCKKYGSLFIADEI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHCCEEEEHHH
QTGMGRTGRFLAVEHWNVEPDMVLLSKALSGGHVPVGALLTRKAIFDKIFNRMDRAVVHG
HHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
STFAKNDLAMAAGIATLEVLKAEKLIEAAAKRGAELRLALTRMVPGYELLKEVRGKGLMI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCHHHHHHHCCCEEEE
GVEFGPPKSLRLKASWTMLESANKGLFCQLITVPLFKDHKILTQVAGHGLHTIKLLPPLT
EEECCCCCCEEEEEHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCE
ITEDDCNWIERAFDDVIAQSHKVPGAIWSLGKTLVDNAIRKSA
EECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKSNLDVSEMFVERQAQRSTMHSRHLNEQLVRVLKTIGYDVGFQKGQGQYLYDRDGARY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHH
LDLLSGFGVFAIGRNHPTLRDALKSVLDSDLPNLVQLDVSTLAGVLAERLLEYVPYLDKV
HHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFANSGAETVEAAIKFARGATGRPGIVYCGHSYHGLTYGALSLTEDSNFRTGFEPLLPGC
HHCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCHHHCCCC
TAVPFNDLAALEQALASREIAAFIVEPIQGKGVNMPTDEFLPGAAALCKKYGSLFIADEI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHCCEEEEHHH
QTGMGRTGRFLAVEHWNVEPDMVLLSKALSGGHVPVGALLTRKAIFDKIFNRMDRAVVHG
HHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
STFAKNDLAMAAGIATLEVLKAEKLIEAAAKRGAELRLALTRMVPGYELLKEVRGKGLMI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCHHHHHHHCCCEEEE
GVEFGPPKSLRLKASWTMLESANKGLFCQLITVPLFKDHKILTQVAGHGLHTIKLLPPLT
EEECCCCCCEEEEEHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCE
ITEDDCNWIERAFDDVIAQSHKVPGAIWSLGKTLVDNAIRKSA
EECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]