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The map label for this gene is paaG [H]

Identifier: 146339580

GI number: 146339580

Start: 2752639

End: 2753433

Strand: Direct

Name: paaG [H]

Synonym: BRADO2571

Alternate gene names: 146339580

Gene position: 2752639-2753433 (Clockwise)

Preceding gene: 146339577

Following gene: 146339581

Centisome position: 36.92

GC content: 65.79

Gene sequence:

>795_bases
ATGCAATTCAAGCACGTCACGCTCGATTTCGACGGGCCCGTCGCCATCCTCACGCTGGATCATCAGGAGGTGATGAACGC
GGTTTCGATCGACATGCTCGGCGGCCTTGCCGAGGCGCTCGACGAAATCGAGGAGAGGAAAGCCGACGTACGCTGTCTCG
TCGTGACCGGCGCCGGGCGCGCGTTCTGCACCGGCGCCAATCTGCAGGGCCGCAACGCGCAGGCTAAGCCCGGTCGCAGC
AATGCGGGCGCGGCGCTCGAGACCGCCTTTCATCCCTTCCTTCGCCGCCTGCGCAATCTGCATTGTCCGATCGTCACCTC
GGTGAACGGCCCGGCGGCGGGCGCCGGCATGAGCTTCGCGCTGATGGGCGACATGATCCTGTGCGCCAAGTCCGCGTACT
TCCTGCAGGCCTTCCGCCGCATCGGCCTGGTGCCGGATTGCGGCTCGACTTGGCTGCTGCCGCGCCTTGTCGGCAAGGCC
CGCGCGATCGAGCTGTCGCTGCTCGGTGAGAAGCTGCCGGCCGAGACGGCACTGCAATGGGGCCTCGTCAACCGCATCTA
TGACGATGCGGCGCTGAAAGAGGAGACGATGAAGCTCGCGCACGAGCTCGCCAACGGCCCGACGGTCGCGCTGGCGCAGA
TCCGTCGTCTCTATTGGGAGAGCCCGGAGAACTCGTTCGAGGAGCAGCTCAACGAGGAATTCCAGTCGCAGCGCATCGCC
GGCAGCACCGCCGACTTCAAGGAGGGCGTCACCGCCTTCCTCGAGAAGCGTCCCGCCAAGTTCAAGGGCCAATGA

Upstream 100 bases:

>100_bases
ACAAGCGAAGCGCAAAAATCAAATATGCTGCACGCACCGGCAAACTTGCGAATTTCCGCCGCGAAGAATGCAGCGCCCGA
ACAGCTCTTGAGAGGAAACC

Downstream 100 bases:

>100_bases
TCGAGACCGAGCTGTCAGCTTGCGTCGCCGCGTTCATGCCGGGTGCGACCGGTGTGCGTGGCGCCGCGAAGCTCTCCGGC
GGTGCCAGCCAGGAGACGTG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MQFKHVTLDFDGPVAILTLDHQEVMNAVSIDMLGGLAEALDEIEERKADVRCLVVTGAGRAFCTGANLQGRNAQAKPGRS
NAGAALETAFHPFLRRLRNLHCPIVTSVNGPAAGAGMSFALMGDMILCAKSAYFLQAFRRIGLVPDCGSTWLLPRLVGKA
RAIELSLLGEKLPAETALQWGLVNRIYDDAALKEETMKLAHELANGPTVALAQIRRLYWESPENSFEEQLNEEFQSQRIA
GSTADFKEGVTAFLEKRPAKFKGQ

Sequences:

>Translated_264_residues
MQFKHVTLDFDGPVAILTLDHQEVMNAVSIDMLGGLAEALDEIEERKADVRCLVVTGAGRAFCTGANLQGRNAQAKPGRS
NAGAALETAFHPFLRRLRNLHCPIVTSVNGPAAGAGMSFALMGDMILCAKSAYFLQAFRRIGLVPDCGSTWLLPRLVGKA
RAIELSLLGEKLPAETALQWGLVNRIYDDAALKEETMKLAHELANGPTVALAQIRRLYWESPENSFEEQLNEEFQSQRIA
GSTADFKEGVTAFLEKRPAKFKGQ
>Mature_264_residues
MQFKHVTLDFDGPVAILTLDHQEVMNAVSIDMLGGLAEALDEIEERKADVRCLVVTGAGRAFCTGANLQGRNAQAKPGRS
NAGAALETAFHPFLRRLRNLHCPIVTSVNGPAAGAGMSFALMGDMILCAKSAYFLQAFRRIGLVPDCGSTWLLPRLVGKA
RAIELSLLGEKLPAETALQWGLVNRIYDDAALKEETMKLAHELANGPTVALAQIRRLYWESPENSFEEQLNEEFQSQRIA
GSTADFKEGVTAFLEKRPAKFKGQ

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=259, Percent_Identity=32.4324324324324, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI25453481, Length=251, Percent_Identity=25.4980079681275, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI51538573, Length=251, Percent_Identity=25.4980079681275, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI4757968, Length=251, Percent_Identity=25.4980079681275, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI49355787, Length=251, Percent_Identity=25.4980079681275, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI4757966, Length=207, Percent_Identity=27.0531400966184, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI51538581, Length=207, Percent_Identity=27.0531400966184, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI116235487, Length=169, Percent_Identity=27.2189349112426, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI221136756, Length=213, Percent_Identity=24.8826291079812, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221136753, Length=213, Percent_Identity=24.8826291079812, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221307494, Length=169, Percent_Identity=28.4023668639053, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI31542718, Length=253, Percent_Identity=26.0869565217391, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI70995211, Length=234, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI45643119, Length=201, Percent_Identity=24.8756218905473, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI260275230, Length=201, Percent_Identity=24.8756218905473, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI260274832, Length=201, Percent_Identity=24.8756218905473, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI213417737, Length=238, Percent_Identity=26.890756302521, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI157694516, Length=238, Percent_Identity=26.890756302521, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI4502327, Length=279, Percent_Identity=27.5985663082437, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787660, Length=251, Percent_Identity=43.8247011952191, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI221142681, Length=224, Percent_Identity=31.6964285714286, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787659, Length=253, Percent_Identity=30.8300395256917, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082183, Length=268, Percent_Identity=22.7611940298507, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788597, Length=260, Percent_Identity=25.3846153846154, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788682, Length=192, Percent_Identity=24.4791666666667, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17560910, Length=250, Percent_Identity=28.8, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=29.0322580645161, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17554946, Length=251, Percent_Identity=27.8884462151394, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17540306, Length=259, Percent_Identity=25.0965250965251, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17535521, Length=246, Percent_Identity=26.4227642276423, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17549921, Length=184, Percent_Identity=25, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=29.8387096774194, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=29.8387096774194, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24654903, Length=255, Percent_Identity=27.4509803921569, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19922422, Length=256, Percent_Identity=24.609375, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI19920382, Length=241, Percent_Identity=26.5560165975104, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24650670, Length=254, Percent_Identity=25.5905511811024, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=27.5471698113208, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571729, Length=234, Percent_Identity=22.6495726495727, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571730, Length=234, Percent_Identity=22.6495726495727, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357171, Length=255, Percent_Identity=25.4901960784314, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28814; Mature: 28814

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFKHVTLDFDGPVAILTLDHQEVMNAVSIDMLGGLAEALDEIEERKADVRCLVVTGAGR
CCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
AFCTGANLQGRNAQAKPGRSNAGAALETAFHPFLRRLRNLHCPIVTSVNGPAAGAGMSFA
EEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHH
LMGDMILCAKSAYFLQAFRRIGLVPDCGSTWLLPRLVGKARAIELSLLGEKLPAETALQW
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHEEHHHHHCCCCCHHHHHHH
GLVNRIYDDAALKEETMKLAHELANGPTVALAQIRRLYWESPENSFEEQLNEEFQSQRIA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
GSTADFKEGVTAFLEKRPAKFKGQ
CCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQFKHVTLDFDGPVAILTLDHQEVMNAVSIDMLGGLAEALDEIEERKADVRCLVVTGAGR
CCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
AFCTGANLQGRNAQAKPGRSNAGAALETAFHPFLRRLRNLHCPIVTSVNGPAAGAGMSFA
EEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHH
LMGDMILCAKSAYFLQAFRRIGLVPDCGSTWLLPRLVGKARAIELSLLGEKLPAETALQW
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHEEHHHHHCCCCCHHHHHHH
GLVNRIYDDAALKEETMKLAHELANGPTVALAQIRRLYWESPENSFEEQLNEEFQSQRIA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
GSTADFKEGVTAFLEKRPAKFKGQ
CCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]