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The map label for this gene is mcp4 [H]

Identifier: 146339088

GI number: 146339088

Start: 2176271

End: 2178022

Strand: Direct

Name: mcp4 [H]

Synonym: BRADO2042

Alternate gene names: 146339088

Gene position: 2176271-2178022 (Clockwise)

Preceding gene: 146339087

Following gene: 146339094

Centisome position: 29.19

GC content: 67.47

Gene sequence:

>1752_bases
ATGGCGTCGTGGCCGCGCAGATACGACCGGTGGTGCGAGACGTTTTCTCTCGGAGGATCAACGGACGTGTCCAAGCTTTC
CATTCGCCTCAAGATCATCAGCGTGATCGCCTTCCTGCTGGTGGTGATGGCCGGCATGGGCCTGCTGTCGCTGCGCAGCA
TGCGCGACATCAATGCGCGAACGGTCGACATATCCACCAACTGGCTGCCGAGCGTGCGGGCGCTCGGGGCATTGCGCGCA
GACATCAACGTCTACCGGCTCACGCTCCGCGCCCATGTGATGGCGCTAACGGCCGAGGCCAAGGCCAACAACGACAAGCG
CATGGCCGAGGTGTTCGCAAAGGTGCAGAAGGACATCAAGGCCTATCAGCCGCTGATCTCGACGCCGGAGGAGCGCAGCA
TCTACGACTCCTGGGTGCGGGCCTGGGACAACTACACGGCCGAGGCCGACAAGGTGCTTGAGGTCTCGCGCAGGAGCATC
GGCAAGCTGCCCGAGGACGTCGATGCGCTGTTCAAGGCCCCCGGTGCGGCCGCGACGGTGCAAGAGGACATCCTCACCAA
GGCGATCGAATACAACGACAAGGGCGCCGAAGCGGCCACGCGCGACGCGGCGGATGGCTACAACAGCACCTTCTGGGTGG
TGACCTCGATCATTCTCGCGGCCGTCGCCGCCGGTGTCGCCGTCGGCTTCTATCTCGTCAACGACGTCTCTTCCGGCATC
GCCTCGATCATCAAGCCGATGCAGGCGCTCGGCGAGGGCGATCTCTCGGCCGAGGTGCCGCACCGCGGCGAGCCGACCGA
GATGGGTGCGATGGCCGACACGCTGCAGGTGTTCAAGGAGGCGCTGATCGCCAAGCGCGACGCCGATGCGCGCGCCGCGG
CCGACGCCGAGGCCAAGATCGAGCGCGGCCGCCGCGTCGACAACATCACCCGCCAGTTCGAGAACACGATCGGCGAGATC
GTGCAGACGGTGTCGTCGGCTTCGACCGAGCTCGAGCATTCCGCGGGCGCGCTGTCGTCGACCGCGACGCGGTCCCAGGA
GATCTCGACCGCGGTCGCGGCGGCCTCGGAGGAGGCGTCGACCAACGTGCAGTCGGTCGCCTCCGCTACCGAGGAGCTGT
CGTCGTCCATCACCGAGATCAGCCGCCAGGTTCAGGAATCCGCGCGCATGGCTTCGGAGGCCGTGACGCAGGCGCGTCAG
ACCAATGACCGCGTCAGCGAATTGTCGAAGGCCGCGGCGCGCATCGGGGATGTCGTCGAGCTGATCAACTCGATCGCCGG
CCAGACCAACCTGCTCGCCCTGAACGCAACGATCGAGGCCGCGCGCGCCGGCGAGGCTGGTCGCGGCTTCGCGGTGGTCG
CGTCCGAGGTGAAGGCATTGGCCGAGCAGACCTCGAAGGCCACCGGCGAGATCGGCCAGCAGATCTCCGGCATTCAGGCG
GCGACGCAGGAATCGGTCGGCGCCATCCGTGACATCTCCGGGACGATCGAGCGGCTCTCGGAGATCTCGTCGGCGATCGC
GGCTGCGGTCGAGGAGCAGGGCGCGGCAACGCAGGAGATCTCCCGCAACGTCCAGCAGGCCTCGCATGGCACCCAGCAGG
TCTCGTCCAGCGTCGTCGACGTGCAGCGCGGCGCAGCGGAGACCGGCCAGGCGTCGGCGCATGTCCTCGGCGCCGCCAAG
TCGCTGGCCACGGACAGCGACCGGCTCAAGCGGGAGGTCGCTTCGTTCCTGCAGTCGGTTCGCGCCGCCTGA

Upstream 100 bases:

>100_bases
GTACGAAGGTCTGCGTTAACGGAACTTTGCGGACGAAGCGGCAAACTGCGCGGCGGCAGTTGCCGCTTTTTCGTTTCGCA
GCGGTACGCCGGCCATCGCA

Downstream 100 bases:

>100_bases
CGATCACGCCGCCGGCGCAGCAGGCGGGGCCTGCTGCTGCCGCCGGAACAGCACCTTCTGATACAGCCAGCCGATCGCGA
CCAGCACCAGGCCGAGGCCG

Product: putative methyl-accepting chemotaxis receptor/sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MASWPRRYDRWCETFSLGGSTDVSKLSIRLKIISVIAFLLVVMAGMGLLSLRSMRDINARTVDISTNWLPSVRALGALRA
DINVYRLTLRAHVMALTAEAKANNDKRMAEVFAKVQKDIKAYQPLISTPEERSIYDSWVRAWDNYTAEADKVLEVSRRSI
GKLPEDVDALFKAPGAAATVQEDILTKAIEYNDKGAEAATRDAADGYNSTFWVVTSIILAAVAAGVAVGFYLVNDVSSGI
ASIIKPMQALGEGDLSAEVPHRGEPTEMGAMADTLQVFKEALIAKRDADARAAADAEAKIERGRRVDNITRQFENTIGEI
VQTVSSASTELEHSAGALSSTATRSQEISTAVAAASEEASTNVQSVASATEELSSSITEISRQVQESARMASEAVTQARQ
TNDRVSELSKAAARIGDVVELINSIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTSKATGEIGQQISGIQA
ATQESVGAIRDISGTIERLSEISSAIAAAVEEQGAATQEISRNVQQASHGTQQVSSSVVDVQRGAAETGQASAHVLGAAK
SLATDSDRLKREVASFLQSVRAA

Sequences:

>Translated_583_residues
MASWPRRYDRWCETFSLGGSTDVSKLSIRLKIISVIAFLLVVMAGMGLLSLRSMRDINARTVDISTNWLPSVRALGALRA
DINVYRLTLRAHVMALTAEAKANNDKRMAEVFAKVQKDIKAYQPLISTPEERSIYDSWVRAWDNYTAEADKVLEVSRRSI
GKLPEDVDALFKAPGAAATVQEDILTKAIEYNDKGAEAATRDAADGYNSTFWVVTSIILAAVAAGVAVGFYLVNDVSSGI
ASIIKPMQALGEGDLSAEVPHRGEPTEMGAMADTLQVFKEALIAKRDADARAAADAEAKIERGRRVDNITRQFENTIGEI
VQTVSSASTELEHSAGALSSTATRSQEISTAVAAASEEASTNVQSVASATEELSSSITEISRQVQESARMASEAVTQARQ
TNDRVSELSKAAARIGDVVELINSIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTSKATGEIGQQISGIQA
ATQESVGAIRDISGTIERLSEISSAIAAAVEEQGAATQEISRNVQQASHGTQQVSSSVVDVQRGAAETGQASAHVLGAAK
SLATDSDRLKREVASFLQSVRAA
>Mature_582_residues
ASWPRRYDRWCETFSLGGSTDVSKLSIRLKIISVIAFLLVVMAGMGLLSLRSMRDINARTVDISTNWLPSVRALGALRAD
INVYRLTLRAHVMALTAEAKANNDKRMAEVFAKVQKDIKAYQPLISTPEERSIYDSWVRAWDNYTAEADKVLEVSRRSIG
KLPEDVDALFKAPGAAATVQEDILTKAIEYNDKGAEAATRDAADGYNSTFWVVTSIILAAVAAGVAVGFYLVNDVSSGIA
SIIKPMQALGEGDLSAEVPHRGEPTEMGAMADTLQVFKEALIAKRDADARAAADAEAKIERGRRVDNITRQFENTIGEIV
QTVSSASTELEHSAGALSSTATRSQEISTAVAAASEEASTNVQSVASATEELSSSITEISRQVQESARMASEAVTQARQT
NDRVSELSKAAARIGDVVELINSIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTSKATGEIGQQISGIQAA
TQESVGAIRDISGTIERLSEISSAIAAAVEEQGAATQEISRNVQQASHGTQQVSSSVVDVQRGAAETGQASAHVLGAAKS
LATDSDRLKREVASFLQSVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=558, Percent_Identity=23.6559139784946, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788194, Length=283, Percent_Identity=30.0353356890459, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788195, Length=268, Percent_Identity=30.9701492537313, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787690, Length=248, Percent_Identity=30.6451612903226, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1789453, Length=233, Percent_Identity=31.7596566523605, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 61802; Mature: 61671

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASWPRRYDRWCETFSLGGSTDVSKLSIRLKIISVIAFLLVVMAGMGLLSLRSMRDINAR
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
TVDISTNWLPSVRALGALRADINVYRLTLRAHVMALTAEAKANNDKRMAEVFAKVQKDIK
EEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AYQPLISTPEERSIYDSWVRAWDNYTAEADKVLEVSRRSIGKLPEDVDALFKAPGAAATV
HHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHH
QEDILTKAIEYNDKGAEAATRDAADGYNSTFWVVTSIILAAVAAGVAVGFYLVNDVSSGI
HHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASIIKPMQALGEGDLSAEVPHRGEPTEMGAMADTLQVFKEALIAKRDADARAAADAEAKI
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHH
ERGRRVDNITRQFENTIGEIVQTVSSASTELEHSAGALSSTATRSQEISTAVAAASEEAS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
TNVQSVASATEELSSSITEISRQVQESARMASEAVTQARQTNDRVSELSKAAARIGDVVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINSIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTSKATGEIGQQISGIQA
HHHHHCCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATQESVGAIRDISGTIERLSEISSAIAAAVEEQGAATQEISRNVQQASHGTQQVSSSVVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VQRGAAETGQASAHVLGAAKSLATDSDRLKREVASFLQSVRAA
HHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASWPRRYDRWCETFSLGGSTDVSKLSIRLKIISVIAFLLVVMAGMGLLSLRSMRDINAR
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
TVDISTNWLPSVRALGALRADINVYRLTLRAHVMALTAEAKANNDKRMAEVFAKVQKDIK
EEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AYQPLISTPEERSIYDSWVRAWDNYTAEADKVLEVSRRSIGKLPEDVDALFKAPGAAATV
HHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHH
QEDILTKAIEYNDKGAEAATRDAADGYNSTFWVVTSIILAAVAAGVAVGFYLVNDVSSGI
HHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASIIKPMQALGEGDLSAEVPHRGEPTEMGAMADTLQVFKEALIAKRDADARAAADAEAKI
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHH
ERGRRVDNITRQFENTIGEIVQTVSSASTELEHSAGALSSTATRSQEISTAVAAASEEAS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
TNVQSVASATEELSSSITEISRQVQESARMASEAVTQARQTNDRVSELSKAAARIGDVVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINSIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTSKATGEIGQQISGIQA
HHHHHCCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATQESVGAIRDISGTIERLSEISSAIAAAVEEQGAATQEISRNVQQASHGTQQVSSSVVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VQRGAAETGQASAHVLGAAKSLATDSDRLKREVASFLQSVRAA
HHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]