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The map label for this gene is nhaA [H]

Identifier: 146339073

GI number: 146339073

Start: 2157065

End: 2157931

Strand: Direct

Name: nhaA [H]

Synonym: BRADO2027

Alternate gene names: 146339073

Gene position: 2157065-2157931 (Clockwise)

Preceding gene: 146339071

Following gene: 146339074

Centisome position: 28.93

GC content: 69.2

Gene sequence:

>867_bases
TTGAAGGCGCTGCTGCCGGCGCGGCTGCGCGGCGCGCCGGTGGTGCCCGTGGTCCGCCTGTCCGGCGTGATCGGCGCGGT
CACGCCGCTGCGACCGGGGCTCACGCTGGCCGGTGTCGCCAAGATGCTCGAGCGCGCGTTCTCGATGCGCAACGCCAAGG
CGGTGGCGCTGGTGATCAACTCGCCCGGCGGCTCGCCGGTGCAGTCTCGCCAGATCTATCTGCGCATCCGCCAGCTCGCC
GCCGAGAAGAAGCTCCCGGTGCTCGTCTTCGTCGAGGATGTCGCGGCGTCCGGCGGCTACATGATCGCCTGCGCGGGCGA
CGAGATCTTTTGCGACCCGTCTTCGATCGTCGGCTCGATCGGCGTCGTCGGCGGCTCGTTCGGCCTGCAGGATCTGATCA
AGAGGATCGGCATCGAGCGCAGGCTGTACACGGCCGGCGAGCACAAGGCGATGCTCGATCCCTTCCTGCCCGAGAATCCG
GACGACGTGGCACGGCTGAAGAAGATCCAGCGCGAGATCCACGCGCTGTTCATCTCGCTGGTCAAGGAGAGCCGCACAAA
CCGGCTGAAGGGTGCCGACGATTTGCTGTTCACGGGCGAGTACTGGGCCGGCGATACCGCGGTGACGCTCGGCCTGGCGG
ATGCGATCGGCGACCTGCGCGCCGTGCTGCGCGCCCGGTTCGGGGACAAGGTCGCGATGCCCGTGGTGGCACCGGCTGGC
GGCCTGCTGTCCGGCCTGCTCGGCCGCAAGTCCGCAGGCGCCGGCAGCCTGACCGCGCAAGGTTTGGGAATCGGCTGGTC
GGGGCTCGCCGAGGAGCTGATCTCCGCGGCCGAAACCCGCGCCATCTGGGCCCGATTTGGCTTTTGA

Upstream 100 bases:

>100_bases
TATTGAATGGCAGCGGCGCGATAAAAAGTGGTTAATCCGAGGTAACAGGATGGTGGACAAATTGACACAACCCAGCGATG
CAGCGGGGCCTTTTGATCGG

Downstream 100 bases:

>100_bases
GCCCTCCCGCGCCATTTTGCCCCCTGCAATCCGGATTGCAGGGGGAACCGGGATCGGCGACAATGCGAGTCGGGGTGGCT
TTCCTCATGAACAAGGATCG

Product: putative serine protease SohB

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKALLPARLRGAPVVPVVRLSGVIGAVTPLRPGLTLAGVAKMLERAFSMRNAKAVALVINSPGGSPVQSRQIYLRIRQLA
AEKKLPVLVFVEDVAASGGYMIACAGDEIFCDPSSIVGSIGVVGGSFGLQDLIKRIGIERRLYTAGEHKAMLDPFLPENP
DDVARLKKIQREIHALFISLVKESRTNRLKGADDLLFTGEYWAGDTAVTLGLADAIGDLRAVLRARFGDKVAMPVVAPAG
GLLSGLLGRKSAGAGSLTAQGLGIGWSGLAEELISAAETRAIWARFGF

Sequences:

>Translated_288_residues
MKALLPARLRGAPVVPVVRLSGVIGAVTPLRPGLTLAGVAKMLERAFSMRNAKAVALVINSPGGSPVQSRQIYLRIRQLA
AEKKLPVLVFVEDVAASGGYMIACAGDEIFCDPSSIVGSIGVVGGSFGLQDLIKRIGIERRLYTAGEHKAMLDPFLPENP
DDVARLKKIQREIHALFISLVKESRTNRLKGADDLLFTGEYWAGDTAVTLGLADAIGDLRAVLRARFGDKVAMPVVAPAG
GLLSGLLGRKSAGAGSLTAQGLGIGWSGLAEELISAAETRAIWARFGF
>Mature_288_residues
MKALLPARLRGAPVVPVVRLSGVIGAVTPLRPGLTLAGVAKMLERAFSMRNAKAVALVINSPGGSPVQSRQIYLRIRQLA
AEKKLPVLVFVEDVAASGGYMIACAGDEIFCDPSSIVGSIGVVGGSFGLQDLIKRIGIERRLYTAGEHKAMLDPFLPENP
DDVARLKKIQREIHALFISLVKESRTNRLKGADDLLFTGEYWAGDTAVTLGLADAIGDLRAVLRARFGDKVAMPVVAPAG
GLLSGLLGRKSAGAGSLTAQGLGIGWSGLAEELISAAETRAIWARFGF

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=210, Percent_Identity=34.7619047619048, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788064, Length=168, Percent_Identity=30.952380952381, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 30352; Mature: 30352

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLPARLRGAPVVPVVRLSGVIGAVTPLRPGLTLAGVAKMLERAFSMRNAKAVALVIN
CCCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEE
SPGGSPVQSRQIYLRIRQLAAEKKLPVLVFVEDVAASGGYMIACAGDEIFCDPSSIVGSI
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCEEEEEECCEEEECHHHHHHHH
GVVGGSFGLQDLIKRIGIERRLYTAGEHKAMLDPFLPENPDDVARLKKIQREIHALFISL
HHCCCCCCHHHHHHHHCCCCEEECCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VKESRTNRLKGADDLLFTGEYWAGDTAVTLGLADAIGDLRAVLRARFGDKVAMPVVAPAG
HHHHHHCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCEECCCH
GLLSGLLGRKSAGAGSLTAQGLGIGWSGLAEELISAAETRAIWARFGF
HHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKALLPARLRGAPVVPVVRLSGVIGAVTPLRPGLTLAGVAKMLERAFSMRNAKAVALVIN
CCCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEE
SPGGSPVQSRQIYLRIRQLAAEKKLPVLVFVEDVAASGGYMIACAGDEIFCDPSSIVGSI
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCEEEEEECCEEEECHHHHHHHH
GVVGGSFGLQDLIKRIGIERRLYTAGEHKAMLDPFLPENPDDVARLKKIQREIHALFISL
HHCCCCCCHHHHHHHHCCCCEEECCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VKESRTNRLKGADDLLFTGEYWAGDTAVTLGLADAIGDLRAVLRARFGDKVAMPVVAPAG
HHHHHHCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCEECCCH
GLLSGLLGRKSAGAGSLTAQGLGIGWSGLAEELISAAETRAIWARFGF
HHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA