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The map label for this gene is pgm [H]

Identifier: 146338989

GI number: 146338989

Start: 2058846

End: 2060486

Strand: Reverse

Name: pgm [H]

Synonym: BRADO1937

Alternate gene names: 146338989

Gene position: 2060486-2058846 (Counterclockwise)

Preceding gene: 146338990

Following gene: 146338988

Centisome position: 27.63

GC content: 66.54

Gene sequence:

>1641_bases
ATGGCCAAGACAGACCCCGCTGCCGGCAAGCCGATCGCCAATGCCGCGCTCGCCAACATTCCGCGGCTGATCACGGCCTA
TTATGCGCTGAAGCCCGATCCGCATGAGCCGACCCAGCGGGTCGCGTTCGGCACCTCGGGCCATCGCGGCTCATCGCTGA
AGACCGGCTTCAACGAGAACCACATTCTGGCCACCACGCAGGCGCTGTGCGACTACCGCCGCCAGCAGGGCCTCGATGGC
CCGCTGTTCGTCGGCATCGACACCCATGCGCTAGCCGAGCCGGCGCTCGCCAGCGCGCTCGAAGTGTTCGGCGCCAACGG
CGTCGAGGTGATGGTCGACAAGGACGGCGGCTACACGCCGACGCCGGTGATCTCGCACGCCATCATCTCCTACAACAAGG
GCCGCACGGCGCATCTTGCCGATGGCGTCGTCATCACGCCGTCACACAATCCGCCGGAGGATGGCGGCTACAAATACAAT
CCGCCGCATGGCGGCCCGGCCGACACCGACGCGACCGCCGAGATCGAGCGGCAGGCCAATGTCTATCTCGCCAACGACCT
CGATGGCGTGTCGCGCATCAGCTACGCCCAGGCCAAGCAGCGCGGCTCGGTGCATCCTCACGACTACATCACGCCCTATG
TGGCCGATCTCGCCAACACCGTCGATCTCGACGCGGTAAAGTCCGCCGGGATCAAGATCGGCATCGATCCGCTCGGCGGC
GCCGCGATCGCCTACTGGGCGCCGATCATCGAGCGCTACGGTCTCAGCGCCACGATCGTCAACGACCTGGTCGACCCGAC
CTTCCGCTTCATGACCGCCGACTGGGACGGCAAGATCCGGATGGACTGCTCCTCGCCCTACGCGATGGCCAGCCTGATCG
GCATGCGCGAGCGCTTCGACGTCGCCTTTGCCAACGACACCGACGCGGATCGCCATGGCATCGTCACCCGCTCGGGCGGG
CTGATGAATCCGAACCATTATCTCGCGACCGCGATCGCCTATCTGTTCGCGCACAGGCCGGACTGGCGCAGTGACGCCGC
CATCGGCAAGACAATCGTCTCGAGCTCGCTGATCGACCGTGTCGCGCAGAAGCTCGGTCGCAAGCTGGTGGAGACGCCGG
TCGGCTTCAAATGGTTCGTCGAAGGGCTCGGCTCGGGCAGCTTCGGCTTCGCCGGCGAGGAGAGCGCGGGCGCCTCGTTT
CTCAAGCGCGACGGCACCGTGTGGACCACCGACAAGGACGGCCTGATCCTCGGCCTGCTCGCCGCCGAGATCATGGCCAA
GCGCGGCCGCGATCCGAGCGAGCTCTACAAGGAGCTCGCCTCGGAGCTCGGCGCTCCCGTCTATGAGCGCATCGACGTTC
CGGCCTCGCCGCCGCAGAAGGCGGCGCTCAAGGCGCTGACGCCGGAAAAGCTCGGCCTCAAGGAACTCGCCGGCGATCCC
GTCCGCGTCATCCACACCAAGGCGCCCGGCAACGGCCAATCTTTCGGGGGCATCAAGGTCGAGACCGAGTATGGCTGGTT
CGCGGCGCGCCCCTCGGGCACCGAGGACGTGAACAAGCTCTATGCCGAGAGTTTCCGCGACGCCGAGCATCTCAAGCGAA
TCCAGAGCGAGGCGCAGGCGGCACTGGCGAAGGTAGCGTAG

Upstream 100 bases:

>100_bases
GCCGCCATGTTGGCGGTCGAGATCGCCCTCTTGCCGCACGCATGGCCGGGCGGAACGAAGCGGCTCTGCCGATGTTTTTC
GAACTTGCGAAGGATGCTCC

Downstream 100 bases:

>100_bases
CGTCGCGTGCGCGCTGAGATTCGACGCGGGTGTGATCACCTGCACATACGCGTCGGGCCGGCCGGACTACATCCCTGACA
TGGACTGCATCGGGCAGCCA

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MAKTDPAAGKPIANAALANIPRLITAYYALKPDPHEPTQRVAFGTSGHRGSSLKTGFNENHILATTQALCDYRRQQGLDG
PLFVGIDTHALAEPALASALEVFGANGVEVMVDKDGGYTPTPVISHAIISYNKGRTAHLADGVVITPSHNPPEDGGYKYN
PPHGGPADTDATAEIERQANVYLANDLDGVSRISYAQAKQRGSVHPHDYITPYVADLANTVDLDAVKSAGIKIGIDPLGG
AAIAYWAPIIERYGLSATIVNDLVDPTFRFMTADWDGKIRMDCSSPYAMASLIGMRERFDVAFANDTDADRHGIVTRSGG
LMNPNHYLATAIAYLFAHRPDWRSDAAIGKTIVSSSLIDRVAQKLGRKLVETPVGFKWFVEGLGSGSFGFAGEESAGASF
LKRDGTVWTTDKDGLILGLLAAEIMAKRGRDPSELYKELASELGAPVYERIDVPASPPQKAALKALTPEKLGLKELAGDP
VRVIHTKAPGNGQSFGGIKVETEYGWFAARPSGTEDVNKLYAESFRDAEHLKRIQSEAQAALAKVA

Sequences:

>Translated_546_residues
MAKTDPAAGKPIANAALANIPRLITAYYALKPDPHEPTQRVAFGTSGHRGSSLKTGFNENHILATTQALCDYRRQQGLDG
PLFVGIDTHALAEPALASALEVFGANGVEVMVDKDGGYTPTPVISHAIISYNKGRTAHLADGVVITPSHNPPEDGGYKYN
PPHGGPADTDATAEIERQANVYLANDLDGVSRISYAQAKQRGSVHPHDYITPYVADLANTVDLDAVKSAGIKIGIDPLGG
AAIAYWAPIIERYGLSATIVNDLVDPTFRFMTADWDGKIRMDCSSPYAMASLIGMRERFDVAFANDTDADRHGIVTRSGG
LMNPNHYLATAIAYLFAHRPDWRSDAAIGKTIVSSSLIDRVAQKLGRKLVETPVGFKWFVEGLGSGSFGFAGEESAGASF
LKRDGTVWTTDKDGLILGLLAAEIMAKRGRDPSELYKELASELGAPVYERIDVPASPPQKAALKALTPEKLGLKELAGDP
VRVIHTKAPGNGQSFGGIKVETEYGWFAARPSGTEDVNKLYAESFRDAEHLKRIQSEAQAALAKVA
>Mature_545_residues
AKTDPAAGKPIANAALANIPRLITAYYALKPDPHEPTQRVAFGTSGHRGSSLKTGFNENHILATTQALCDYRRQQGLDGP
LFVGIDTHALAEPALASALEVFGANGVEVMVDKDGGYTPTPVISHAIISYNKGRTAHLADGVVITPSHNPPEDGGYKYNP
PHGGPADTDATAEIERQANVYLANDLDGVSRISYAQAKQRGSVHPHDYITPYVADLANTVDLDAVKSAGIKIGIDPLGGA
AIAYWAPIIERYGLSATIVNDLVDPTFRFMTADWDGKIRMDCSSPYAMASLIGMRERFDVAFANDTDADRHGIVTRSGGL
MNPNHYLATAIAYLFAHRPDWRSDAAIGKTIVSSSLIDRVAQKLGRKLVETPVGFKWFVEGLGSGSFGFAGEESAGASFL
KRDGTVWTTDKDGLILGLLAAEIMAKRGRDPSELYKELASELGAPVYERIDVPASPPQKAALKALTPEKLGLKELAGDPV
RVIHTKAPGNGQSFGGIKVETEYGWFAARPSGTEDVNKLYAESFRDAEHLKRIQSEAQAALAKVA

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI133922562, Length=467, Percent_Identity=26.338329764454, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI290463102, Length=435, Percent_Identity=27.5862068965517, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI21361621, Length=435, Percent_Identity=27.1264367816092, Blast_Score=90, Evalue=6e-18,
Organism=Escherichia coli, GI1786904, Length=538, Percent_Identity=58.364312267658, Blast_Score=627, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=458, Percent_Identity=27.5109170305677, Blast_Score=99, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6322722, Length=447, Percent_Identity=29.082774049217, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323752, Length=468, Percent_Identity=26.4957264957265, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17864244, Length=432, Percent_Identity=27.0833333333333, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 58463; Mature: 58332

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTDPAAGKPIANAALANIPRLITAYYALKPDPHEPTQRVAFGTSGHRGSSLKTGFNEN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCCCCCCCCCCCC
HILATTQALCDYRRQQGLDGPLFVGIDTHALAEPALASALEVFGANGVEVMVDKDGGYTP
EEEEHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
TPVISHAIISYNKGRTAHLADGVVITPSHNPPEDGGYKYNPPHGGPADTDATAEIERQAN
CHHHHHHHHCCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
VYLANDLDGVSRISYAQAKQRGSVHPHDYITPYVADLANTVDLDAVKSAGIKIGIDPLGG
EEEECCCCHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHCCHHHHHHCCCEEECCCCCC
AAIAYWAPIIERYGLSATIVNDLVDPTFRFMTADWDGKIRMDCSSPYAMASLIGMRERFD
HHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHCC
VAFANDTDADRHGIVTRSGGLMNPNHYLATAIAYLFAHRPDWRSDAAIGKTIVSSSLIDR
EEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
VAQKLGRKLVETPVGFKWFVEGLGSGSFGFAGEESAGASFLKRDGTVWTTDKDGLILGLL
HHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCHHHHHH
AAEIMAKRGRDPSELYKELASELGAPVYERIDVPASPPQKAALKALTPEKLGLKELAGDP
HHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHCCCHHCCHHHHCCCC
VRVIHTKAPGNGQSFGGIKVETEYGWFAARPSGTEDVNKLYAESFRDAEHLKRIQSEAQA
EEEEEECCCCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
ALAKVA
HHHHCC
>Mature Secondary Structure 
AKTDPAAGKPIANAALANIPRLITAYYALKPDPHEPTQRVAFGTSGHRGSSLKTGFNEN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCCCCCCCCCCCC
HILATTQALCDYRRQQGLDGPLFVGIDTHALAEPALASALEVFGANGVEVMVDKDGGYTP
EEEEHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
TPVISHAIISYNKGRTAHLADGVVITPSHNPPEDGGYKYNPPHGGPADTDATAEIERQAN
CHHHHHHHHCCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
VYLANDLDGVSRISYAQAKQRGSVHPHDYITPYVADLANTVDLDAVKSAGIKIGIDPLGG
EEEECCCCHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHCCHHHHHHCCCEEECCCCCC
AAIAYWAPIIERYGLSATIVNDLVDPTFRFMTADWDGKIRMDCSSPYAMASLIGMRERFD
HHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHCC
VAFANDTDADRHGIVTRSGGLMNPNHYLATAIAYLFAHRPDWRSDAAIGKTIVSSSLIDR
EEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
VAQKLGRKLVETPVGFKWFVEGLGSGSFGFAGEESAGASFLKRDGTVWTTDKDGLILGLL
HHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCHHHHHH
AAEIMAKRGRDPSELYKELASELGAPVYERIDVPASPPQKAALKALTPEKLGLKELAGDP
HHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHCCCHHCCHHHHCCCC
VRVIHTKAPGNGQSFGGIKVETEYGWFAARPSGTEDVNKLYAESFRDAEHLKRIQSEAQA
EEEEEECCCCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
ALAKVA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025683 [H]