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The map label for this gene is nahR [H]

Identifier: 146338916

GI number: 146338916

Start: 1981100

End: 1982032

Strand: Reverse

Name: nahR [H]

Synonym: BRADO1856

Alternate gene names: 146338916

Gene position: 1982032-1981100 (Counterclockwise)

Preceding gene: 146338919

Following gene: 146338915

Centisome position: 26.58

GC content: 68.6

Gene sequence:

>933_bases
ATGGCCAATATCGACAGAGCCGATCTTCGCGACGTGGATCTCAATCTGCTGGTCGCCTTCGAGGCGCTGATGCAGACGCG
CTCGGTGTCGCGCATGGCGCAGCGGCTGCGAATCGGACAGCCCTCGGCGAGCCACGCCCTCAAGCGGCTGCGCGCGCTGC
TTGGTGATCCGCTGTTCGTCCGCACGCCGGCCGGCATGATCCCGACGCCGCACGCGCTGGCGCTCGCCGAGCCGATCCGG
GCGATCCTGACCAGCATCGAAAGGACGCTGTTCGCCCGCGCCTCATTCGATCCGCGGGCGGAGCGCCGCGTCTTCCGGAT
TGGCGCGATGGACTATGTGCAGGCGGTGATCGCCGATCCGCTGCTCGCGGTGCTCCAGGCGCAGGCCCCCGGCTGCAAGC
TGATCCTGACCACGACCGATTGCGACACCGCGGGGCGGAGCCTCGCGCGCGGCGAGATCGATCTCGCGATCGGCGCGTTC
CCGCAGATCAAGGCCGGATCCCACCAGGAGCTGCTGTATCGGGAGCGCTACGAATGCGTGTTCGACGCCAAGGCCTGCCG
GCTCGGCAAGCGCGTCACCCGCGCGCAATGGCTGGCGCTGCCGCATGTCATCATGTCGGTGCATGGCGATTACTCCGGCC
CGCTCGATGACGTCCTGAAGTCCAGCGGCGAGCAGCGCGAGGTCGCCGTTTCGACGCCGAATTTCCTCGCGATCCCCTTC
CTGCTCCGCAACAAGCGCCTGATCGCGGCGCTGCCATCGCGGATGGCGCGGGCGTTCTGCGGCAGGCTCGGATTGTCGAC
CTGTCCGCTGCCGTTCACCGCGCCGACCTTCGACGTCACGATGATCTGGCATGCGCGGACGGGTGATGAGCCCGGCGCCG
CGTGGCTGCGCGATCAGATCACGGCGATCTGCCGGCGCATCGACGCCGCCTGA

Upstream 100 bases:

>100_bases
CGGGGCTGTCGCGGCCTTGCCGCCCCTGACGCTGATTGCTGGCGATCGCAATGTCCATTGATTAGAATGATTTGGCTCGT
TCATCAAATCGACCATATCG

Downstream 100 bases:

>100_bases
GGAGGAGACCAAGCCATGAAGATCCTCTGCATCGTCACGCTCTCACCGACGGCCGACCGCAACGAGGTCGCCCGCCGATT
GAGCGAGGAATTGCGCGAGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MANIDRADLRDVDLNLLVAFEALMQTRSVSRMAQRLRIGQPSASHALKRLRALLGDPLFVRTPAGMIPTPHALALAEPIR
AILTSIERTLFARASFDPRAERRVFRIGAMDYVQAVIADPLLAVLQAQAPGCKLILTTTDCDTAGRSLARGEIDLAIGAF
PQIKAGSHQELLYRERYECVFDAKACRLGKRVTRAQWLALPHVIMSVHGDYSGPLDDVLKSSGEQREVAVSTPNFLAIPF
LLRNKRLIAALPSRMARAFCGRLGLSTCPLPFTAPTFDVTMIWHARTGDEPGAAWLRDQITAICRRIDAA

Sequences:

>Translated_310_residues
MANIDRADLRDVDLNLLVAFEALMQTRSVSRMAQRLRIGQPSASHALKRLRALLGDPLFVRTPAGMIPTPHALALAEPIR
AILTSIERTLFARASFDPRAERRVFRIGAMDYVQAVIADPLLAVLQAQAPGCKLILTTTDCDTAGRSLARGEIDLAIGAF
PQIKAGSHQELLYRERYECVFDAKACRLGKRVTRAQWLALPHVIMSVHGDYSGPLDDVLKSSGEQREVAVSTPNFLAIPF
LLRNKRLIAALPSRMARAFCGRLGLSTCPLPFTAPTFDVTMIWHARTGDEPGAAWLRDQITAICRRIDAA
>Mature_309_residues
ANIDRADLRDVDLNLLVAFEALMQTRSVSRMAQRLRIGQPSASHALKRLRALLGDPLFVRTPAGMIPTPHALALAEPIRA
ILTSIERTLFARASFDPRAERRVFRIGAMDYVQAVIADPLLAVLQAQAPGCKLILTTTDCDTAGRSLARGEIDLAIGAFP
QIKAGSHQELLYRERYECVFDAKACRLGKRVTRAQWLALPHVIMSVHGDYSGPLDDVLKSSGEQREVAVSTPNFLAIPFL
LRNKRLIAALPSRMARAFCGRLGLSTCPLPFTAPTFDVTMIWHARTGDEPGAAWLRDQITAICRRIDAA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=307, Percent_Identity=23.7785016286645, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790147, Length=303, Percent_Identity=26.0726072607261, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081766, Length=274, Percent_Identity=25.5474452554745, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786820, Length=90, Percent_Identity=42.2222222222222, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34118; Mature: 33987

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIDRADLRDVDLNLLVAFEALMQTRSVSRMAQRLRIGQPSASHALKRLRALLGDPLFV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEE
RTPAGMIPTPHALALAEPIRAILTSIERTLFARASFDPRAERRVFRIGAMDYVQAVIADP
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLAVLQAQAPGCKLILTTTDCDTAGRSLARGEIDLAIGAFPQIKAGSHQELLYRERYECV
HHHHHHCCCCCCEEEEEECCCCHHCHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
FDAKACRLGKRVTRAQWLALPHVIMSVHGDYSGPLDDVLKSSGEQREVAVSTPNFLAIPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEECCCCEEEEHH
LLRNKRLIAALPSRMARAFCGRLGLSTCPLPFTAPTFDVTMIWHARTGDEPGAAWLRDQI
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHH
TAICRRIDAA
HHHHHHHCCC
>Mature Secondary Structure 
ANIDRADLRDVDLNLLVAFEALMQTRSVSRMAQRLRIGQPSASHALKRLRALLGDPLFV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEE
RTPAGMIPTPHALALAEPIRAILTSIERTLFARASFDPRAERRVFRIGAMDYVQAVIADP
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLAVLQAQAPGCKLILTTTDCDTAGRSLARGEIDLAIGAFPQIKAGSHQELLYRERYECV
HHHHHHCCCCCCEEEEEECCCCHHCHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
FDAKACRLGKRVTRAQWLALPHVIMSVHGDYSGPLDDVLKSSGEQREVAVSTPNFLAIPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEECCCCEEEEHH
LLRNKRLIAALPSRMARAFCGRLGLSTCPLPFTAPTFDVTMIWHARTGDEPGAAWLRDQI
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHH
TAICRRIDAA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]