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The map label for this gene is appC [H]

Identifier: 146338655

GI number: 146338655

Start: 1699060

End: 1699902

Strand: Reverse

Name: appC [H]

Synonym: BRADO1586

Alternate gene names: 146338655

Gene position: 1699902-1699060 (Counterclockwise)

Preceding gene: 146338656

Following gene: 146338652

Centisome position: 22.8

GC content: 66.79

Gene sequence:

>843_bases
ATGAAGGCAGTGGCCGCAAGGCGGCTGCGCTGGCCCAATATTCCCCTCTCCGTCACCATCGCGATCGCCTGGATCGCGGC
GATGCTGGTGGTCGCGATCTTCGCCGATCAGATCGCGCCCTACGGCTTCACCAAGTTCGACCTGCGCAACCGTCTGTCCC
TGCCGGGCAACCCGGCGCATTGGCTCGGTACCGACGAGCTCGGCCGCGACGTGCTCTCGCGCCTCATTGTCTCGATCCGC
ATCTCGCTCCTGATCGCGTTCGGCGCCACCGCGATCTCGGCCGTCGCCGGCACCACACTCGGCTTTCTCGCCGCGCATTT
CCGCGGCCTCGTCGAGCAGTTCGTGCTGATGCTCGCGGATTTCCAGGCCAGCATGCCGTTCCTGATCCTCGCGCTCGCGG
TGCTTGCCTTCTTCGGCAACTCGCTGCCGCTCCTGATCGGCCTGATGGGCCTGTTCGGCTGGGAGCGCTACGCGCGCATC
GCGCGCGGGCTGGCGATCTCCGCCAACGCGCAAGGCTATGCCGCCGCCGTGCGCCAGCTCGGCGCGACGCCGCAGCGCGT
ATATCTCAGGCACATCCTGCCGAACATCGCCTCGACACTGATCGTGTCGATGACGCTGGTGTTCCCGGAAGTCATCCTGC
TGGAATCGGGCCTGTCGTTCCTCGGCCTCGGCGTGCAGCCGCCGATGACCAGCCTCGGCAACATGGTCGGCTACGGCCGC
GAATATCTGACGCGCGCGCCATGGATCATGCTCGCACCGGCGGTCACCATCGTGGTGACCACGCTCGCGGTGTCCGTGAT
CGGCGACTGGCTGCGTGACAAGCTCGATCCGACGCTGCAGTGA

Upstream 100 bases:

>100_bases
CGATGACCATGGTGACCTCGAACCTGATCGTCGATTTCCTCTACGGCTTGCTCGATCCGCGGCTTCGCAGCAAGGGAGCC
GCGGCATGACCGACGTCGCA

Downstream 100 bases:

>100_bases
GCGGACTCTAGCGGCGACCCTCCTGACTCGCAGCCGCCGGCTGGTCGCAGACGATCAAGGCATGCCCCGCCTGCTCGCCT
GCGAGCGTCGTCCATTTCGA

Product: putative oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKAVAARRLRWPNIPLSVTIAIAWIAAMLVVAIFADQIAPYGFTKFDLRNRLSLPGNPAHWLGTDELGRDVLSRLIVSIR
ISLLIAFGATAISAVAGTTLGFLAAHFRGLVEQFVLMLADFQASMPFLILALAVLAFFGNSLPLLIGLMGLFGWERYARI
ARGLAISANAQGYAAAVRQLGATPQRVYLRHILPNIASTLIVSMTLVFPEVILLESGLSFLGLGVQPPMTSLGNMVGYGR
EYLTRAPWIMLAPAVTIVVTTLAVSVIGDWLRDKLDPTLQ

Sequences:

>Translated_280_residues
MKAVAARRLRWPNIPLSVTIAIAWIAAMLVVAIFADQIAPYGFTKFDLRNRLSLPGNPAHWLGTDELGRDVLSRLIVSIR
ISLLIAFGATAISAVAGTTLGFLAAHFRGLVEQFVLMLADFQASMPFLILALAVLAFFGNSLPLLIGLMGLFGWERYARI
ARGLAISANAQGYAAAVRQLGATPQRVYLRHILPNIASTLIVSMTLVFPEVILLESGLSFLGLGVQPPMTSLGNMVGYGR
EYLTRAPWIMLAPAVTIVVTTLAVSVIGDWLRDKLDPTLQ
>Mature_280_residues
MKAVAARRLRWPNIPLSVTIAIAWIAAMLVVAIFADQIAPYGFTKFDLRNRLSLPGNPAHWLGTDELGRDVLSRLIVSIR
ISLLIAFGATAISAVAGTTLGFLAAHFRGLVEQFVLMLADFQASMPFLILALAVLAFFGNSLPLLIGLMGLFGWERYARI
ARGLAISANAQGYAAAVRQLGATPQRVYLRHILPNIASTLIVSMTLVFPEVILLESGLSFLGLGVQPPMTSLGNMVGYGR
EYLTRAPWIMLAPAVTIVVTTLAVSVIGDWLRDKLDPTLQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=274, Percent_Identity=35.036496350365, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1787760, Length=264, Percent_Identity=35.2272727272727, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787498, Length=262, Percent_Identity=33.587786259542, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789889, Length=240, Percent_Identity=35, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789964, Length=258, Percent_Identity=36.8217054263566, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787549, Length=261, Percent_Identity=31.4176245210728, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1788505, Length=240, Percent_Identity=27.5, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30297; Mature: 30297

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVAARRLRWPNIPLSVTIAIAWIAAMLVVAIFADQIAPYGFTKFDLRNRLSLPGNPAH
CCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCC
WLGTDELGRDVLSRLIVSIRISLLIAFGATAISAVAGTTLGFLAAHFRGLVEQFVLMLAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQASMPFLILALAVLAFFGNSLPLLIGLMGLFGWERYARIARGLAISANAQGYAAAVRQL
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHH
GATPQRVYLRHILPNIASTLIVSMTLVFPEVILLESGLSFLGLGVQPPMTSLGNMVGYGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHH
EYLTRAPWIMLAPAVTIVVTTLAVSVIGDWLRDKLDPTLQ
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKAVAARRLRWPNIPLSVTIAIAWIAAMLVVAIFADQIAPYGFTKFDLRNRLSLPGNPAH
CCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCC
WLGTDELGRDVLSRLIVSIRISLLIAFGATAISAVAGTTLGFLAAHFRGLVEQFVLMLAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQASMPFLILALAVLAFFGNSLPLLIGLMGLFGWERYARIARGLAISANAQGYAAAVRQL
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHH
GATPQRVYLRHILPNIASTLIVSMTLVFPEVILLESGLSFLGLGVQPPMTSLGNMVGYGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHH
EYLTRAPWIMLAPAVTIVVTTLAVSVIGDWLRDKLDPTLQ
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]