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The map label for this gene is dhlB [H]

Identifier: 146338604

GI number: 146338604

Start: 1636685

End: 1637500

Strand: Reverse

Name: dhlB [H]

Synonym: BRADO1532

Alternate gene names: 146338604

Gene position: 1637500-1636685 (Counterclockwise)

Preceding gene: 146338606

Following gene: 146338599

Centisome position: 21.96

GC content: 63.36

Gene sequence:

>816_bases
TTGCGCCATCGGCTGGCGGAACTCGTATCAGCCCTCCGGGCGCAGCCCGCTCCCGACACAAGGACAGGTCCCGTGGCGAT
CAACACCGTGGTCTTCGACGCTTACGGCACGCTCTACGACATCCAATCCGTGGCGGCGGTCACCGATGCGGCCTTTCCGG
GCCATGGCGACATGATCACGCAGATCTGGCGCATGAAGCAGCTCGAATACACTTGGCTGCGCTCGCTGATGCGGCGCTAC
GAGGATTTCGAGACGGTCACCCGGCAGTCCCTGATCTACACGCTGCGGATTCTCGGACTTCGCTACGAAGAGGCGCTGCT
CGGAACGATCATGGACAAATACGTCCACCTCGATCTCTACCCGGACGCGCTGCCGGCCCTGAACCATCTCCAGGGACGCA
AGCTCGCGATCCTCTCGAACGGCGCGCCAGCGATGTTGAATGCCTTGATCCGAAACACCGGGCTCGATCGCCTGCTCGAC
AAGACCATCAGCGTCGATGCCAGGAGGATCTTCAAGCCCAGCCCCGAAGCCTATTCCTTGATCGAGTCCGAACTCGGCGC
CATGCCCGCCGACGTCCTGTTCGTCAGCTCCAATCCGTGGGACGCAATCGGAGCTAAAGCCTTCGGGCTGAACGTCGCCT
GGATCGAGCGGGTCACGCCCGAAGCGATGGCCGCGGCTTGCGAGCGCAGCACAGTCGTCCCTCCGCTGACGATGTTCAAG
GCGATGCGAACGCAGATGGACGAGCTCGGGCTCGCGCCCGACCACCGGATCCGGGGATTGTCTGAGCTCGCTGGGCTGTT
GCCACTGCTGCCGTAG

Upstream 100 bases:

>100_bases
CGATATCGAAGTTCACGACAATCCCCGCTATCGAAAAAGACGATACTCACATCGTCATTATTCACTTTGTCGGCCGGGCC
ACGCTTCGTAAAGACCAGAC

Downstream 100 bases:

>100_bases
ACCGATCCGCAGCATCCCTACTGATAGCACGCCTCCAGCGCCGCGGCGGCGCGGTACAGCGTCATCTCGTCGAGATGACG
CGCGATCAGCATCGCGCCGA

Product: 2-haloacid dehalogenase

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase; Halocarboxylic acid halidohydrolase; L-2-haloacid dehalogenase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MRHRLAELVSALRAQPAPDTRTGPVAINTVVFDAYGTLYDIQSVAAVTDAAFPGHGDMITQIWRMKQLEYTWLRSLMRRY
EDFETVTRQSLIYTLRILGLRYEEALLGTIMDKYVHLDLYPDALPALNHLQGRKLAILSNGAPAMLNALIRNTGLDRLLD
KTISVDARRIFKPSPEAYSLIESELGAMPADVLFVSSNPWDAIGAKAFGLNVAWIERVTPEAMAAACERSTVVPPLTMFK
AMRTQMDELGLAPDHRIRGLSELAGLLPLLP

Sequences:

>Translated_271_residues
MRHRLAELVSALRAQPAPDTRTGPVAINTVVFDAYGTLYDIQSVAAVTDAAFPGHGDMITQIWRMKQLEYTWLRSLMRRY
EDFETVTRQSLIYTLRILGLRYEEALLGTIMDKYVHLDLYPDALPALNHLQGRKLAILSNGAPAMLNALIRNTGLDRLLD
KTISVDARRIFKPSPEAYSLIESELGAMPADVLFVSSNPWDAIGAKAFGLNVAWIERVTPEAMAAACERSTVVPPLTMFK
AMRTQMDELGLAPDHRIRGLSELAGLLPLLP
>Mature_271_residues
MRHRLAELVSALRAQPAPDTRTGPVAINTVVFDAYGTLYDIQSVAAVTDAAFPGHGDMITQIWRMKQLEYTWLRSLMRRY
EDFETVTRQSLIYTLRILGLRYEEALLGTIMDKYVHLDLYPDALPALNHLQGRKLAILSNGAPAMLNALIRNTGLDRLLD
KTISVDARRIFKPSPEAYSLIESELGAMPADVLFVSSNPWDAIGAKAFGLNVAWIERVTPEAMAAACERSTVVPPLTMFK
AMRTQMDELGLAPDHRIRGLSELAGLLPLLP

Specific function: Catalyzes the hydrolytic dehalogenation of small L-2- haloalkanoic acids to yield the corresponding D-2-hydroxyalkanoic acids. Active with 2-halogenated carboxylic acids and converts only the L-isomer of 2-chloropropionic acid with inversion of configurat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006388
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 30132; Mature: 30132

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHRLAELVSALRAQPAPDTRTGPVAINTVVFDAYGTLYDIQSVAAVTDAAFPGHGDMIT
CCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHH
QIWRMKQLEYTWLRSLMRRYEDFETVTRQSLIYTLRILGLRYEEALLGTIMDKYVHLDLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
PDALPALNHLQGRKLAILSNGAPAMLNALIRNTGLDRLLDKTISVDARRIFKPSPEAYSL
CHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHH
IESELGAMPADVLFVSSNPWDAIGAKAFGLNVAWIERVTPEAMAAACERSTVVPPLTMFK
HHHHHCCCCCCEEEECCCCCHHHCCHHHCCCHHHHHHCCHHHHHHHHHCCCCCCHHHHHH
AMRTQMDELGLAPDHRIRGLSELAGLLPLLP
HHHHHHHHHCCCCCHHHCCHHHHHHHHCCCC
>Mature Secondary Structure
MRHRLAELVSALRAQPAPDTRTGPVAINTVVFDAYGTLYDIQSVAAVTDAAFPGHGDMIT
CCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHH
QIWRMKQLEYTWLRSLMRRYEDFETVTRQSLIYTLRILGLRYEEALLGTIMDKYVHLDLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
PDALPALNHLQGRKLAILSNGAPAMLNALIRNTGLDRLLDKTISVDARRIFKPSPEAYSL
CHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHH
IESELGAMPADVLFVSSNPWDAIGAKAFGLNVAWIERVTPEAMAAACERSTVVPPLTMFK
HHHHHCCCCCCEEEECCCCCHHHCCHHHCCCHHHHHHCCHHHHHHHHHCCCCCCHHHHHH
AMRTQMDELGLAPDHRIRGLSELAGLLPLLP
HHHHHHHHHCCCCCHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1744048; 7580000; 9407083 [H]