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The map label for this gene is ctrA [H]

Identifier: 146338575

GI number: 146338575

Start: 1603833

End: 1604534

Strand: Reverse

Name: ctrA [H]

Synonym: BRADO1497

Alternate gene names: 146338575

Gene position: 1604534-1603833 (Counterclockwise)

Preceding gene: 146338580

Following gene: 146338574

Centisome position: 21.52

GC content: 60.68

Gene sequence:

>702_bases
ATGCGCGTTTTGCTGATTGAGGATGACAGCGCTGTCGCGCAGTCGATCGAGTTGATGTTGAAGTCCGAGAGCTTCAACGT
CTACACGACTGACCTCGGCGAAGAAGGCGTCGACCTCGGCAAGTTGTACGATTACGACATCATCCTTCTCGACCTCAATC
TGCCCGACATGTCCGGTTACGACGTGCTCAAGCAGTTGCGTGTCTCCAAGATCAAGACTCCGATCCTGATCCTGTCCGGC
CTCGCTGGCATCGAGGACAAGGTCAAAGGCCTCGGCTTCGGCGCCGACGACTACATGACCAAGCCATTCCACAAGGACGA
GCTGATCGCCCGCATCCACGCGATCGTCCGCCGCTCCAAGGGCCACGCCCAGTCGGTCATCCAGACCGGCGACCTCGTCG
TGAACCTCGACACCAAGACCGTCGAAGTCGGCGGCCAGCGCGTGCACCTGACCGGCAAGGAATATCAGATGCTGGAGCTG
CTCTCGCTCCGCAAGGGCACCACGCTCACCAAGGAGATGTTCCTCAATCATCTCTACGGCGGCATGGACGAGCCCGAGCT
GAAGATCATCGACGTGTTCATCTGCAAGCTGCGCAAGAAGCTCGCCAACGCCTCCGAAGGCCGCAACTTCATCGAGACCG
TCTGGGGCCGCGGCTACGTGCTGCGCGAGCCGCACGACCTCGACGAGCGCATCCCCGCCTGA

Upstream 100 bases:

>100_bases
ACCATCTCTCGTCAGGATCCGAATCAGTTGTTCAAAGGCGTTTTGAGTGCCGCGATGGCGGCCGACCTGACGCCCGGAGC
GGCGACTATGGGGAACTGGC

Downstream 100 bases:

>100_bases
TCTTTCACTGGGCAACTCGGCAGGCCTCACGGCTTGCTCCTCCCAGACTGGGCCCCGCCGCAAATGGCGGGGTTTTTGTT
TGTGGGGGGGTGGTGTTGCT

Product: two-component cell cycle transcriptional regulator ctrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRVLLIEDDSAVAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYDVLKQLRVSKIKTPILILSG
LAGIEDKVKGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVIQTGDLVVNLDTKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASEGRNFIETVWGRGYVLREPHDLDERIPA

Sequences:

>Translated_233_residues
MRVLLIEDDSAVAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYDVLKQLRVSKIKTPILILSG
LAGIEDKVKGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVIQTGDLVVNLDTKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASEGRNFIETVWGRGYVLREPHDLDERIPA
>Mature_233_residues
MRVLLIEDDSAVAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYDVLKQLRVSKIKTPILILSG
LAGIEDKVKGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVIQTGDLVVNLDTKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASEGRNFIETVWGRGYVLREPHDLDERIPA

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36.4444444444444, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=36.1607142857143, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.9775784753363, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=32.579185520362, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=31.8181818181818, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=31.2217194570136, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=30.4545454545455, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.0748898678414, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=29.2792792792793, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.0748898678414, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=24.6696035242291, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=29.6610169491525, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=25, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=25.5230125523013, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1790299, Length=144, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26203; Mature: 26203

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDDSAVAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCEEEEEEECCCCCCHH
DVLKQLRVSKIKTPILILSGLAGIEDKVKGLGFGADDYMTKPFHKDELIARIHAIVRRSK
HHHHHHHHHHHCCHHHEECCCCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHCC
GHAQSVIQTGDLVVNLDTKTVEVGGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CHHHHHHCCCCEEEEECCEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLANASEGRNFIETVWGRGYVLREPHDLDERIPA
CCCCCCHHHHHHHHHHHHHHHCCHHCCCHHHHHHHCCCEEECCCCCCHHCCCC
>Mature Secondary Structure
MRVLLIEDDSAVAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCEEEEEEECCCCCCHH
DVLKQLRVSKIKTPILILSGLAGIEDKVKGLGFGADDYMTKPFHKDELIARIHAIVRRSK
HHHHHHHHHHHCCHHHEECCCCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHCC
GHAQSVIQTGDLVVNLDTKTVEVGGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CHHHHHHCCCCEEEEECCEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLANASEGRNFIETVWGRGYVLREPHDLDERIPA
CCCCCCHHHHHHHHHHHHHHHCCHHCCCHHHHHHHCCCEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA