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The map label for this gene is cocE [H]

Identifier: 146338502

GI number: 146338502

Start: 1518049

End: 1520007

Strand: Reverse

Name: cocE [H]

Synonym: BRADO1420

Alternate gene names: 146338502

Gene position: 1520007-1518049 (Counterclockwise)

Preceding gene: 146338503

Following gene: 146338500

Centisome position: 20.38

GC content: 67.99

Gene sequence:

>1959_bases
ATGATCGAGCTTGACCGGCTGTCGCGGCGGCGCTTCGTGCAAGGGATGGCGACGCTGGGTGCGGTGGGCGCGGCGCCGGC
GCTCGGGGCAACGGAGACGCCCGCCTCCGACATGCTCGTGGACAAGGGGATCATGGTGGCGATGCGCGACGGCGTGCATC
TGGCGACCGACATCTATTGGCCGGCGAGCGGCGGGAAGCGGCTCGACGGGCGGCTGCCGGTCATCATGAACCGCACGCCC
TATGGGCGCGAGAAGACCGCCGCGCGCGAGATGACGGCCGACGGGCGGCGGCGCACGCGCGCGGAGGTCGCCGGCTATTA
CGTGCGGCGCGGCTATGCCTTCATCTATCAGGACACGCGCGGCCGCGGCGGCAGCGAGGGTCAGTTCGTCAAATATCTCG
ACGACGGCCATGACGGCTTCGACATGTGCCAGTGGATCGTCGCGCAACCTTGGAGCGACGGCCGGATCGGCATGCTCGGG
ACATCCTATGACGCCCATACGCAGGCCGCGGCGGCCTGCGCCGGGGCGCCCGGCCTCAAGGCCGTGTTCCTCGACTTCGG
CGGCTTCTCCAACGCCTATCAGAGCGGCATCCGGCAGGGTGGCGCGTTCGAGCTGAAGCAGGTGACTTGGGCCTATAATC
TGGGGCTCGACAGCCCGGAACTGGCCCGCGACCCCGTTCGCCTCGCCGCGCTCAAGGCCGTCGATCTCAAGGCGTGGTTC
GCGTCGATGCCGTGGAAGCGCGGCCACACGCCGATCAGCCTGATTCCCGACTACGAAGACTACGTCTTCGAGCAGTGGCA
ACACGGCAGCTTCGATGGCTATTGGAAGCGGCTCGGCATCTATGCCGCCGGCTTCTATCCGCAGCTGGCCCGAAGCGCCA
CCGTCCATCTCTCCGGCTGGTACGATCCCTACTCGCGCACGGCGACCGACAATTTCACCGGCACGCGCCAACAGGCATTG
CAGCCGGCGCGGCTCATCCTGGGGCCATGGACGCATGGCGCGCGATCGACCACGTTCGCCGGCGATGTCGATTTTGGGCC
GGAGGCGACCTTCGAGCACGCCACTGGACAGGACTACTTCGCCTATCGCCTCGCCTACTTCGACCGCCACCTGCGCGGCC
TCGAAAACTCGGACCGCGAGCAGCCGCCAGTACGCATCTTCGTGATGGGCGGCGGCAGCGGGCGGCGCAATGCCGAGGGA
CGGCTCGAGCATGGGGGCCGCTGGCGCAGCGAGGCCGACTGGCCGATCCCGCGCACGCGTTGGACGCGTTTCTACTGCCA
CGCATCGGGCGCGCTCGCCGAGTCGCTGCCAGAGGCCGATTCCGAGGCGCTCAGCTACGATTTCGATCCGCGCGATCCCG
TCCCTACGATCGGCGGCGCCGTCACGTCCGGCGAGCCCTTGATGCGCGGCGGCGCCTTCGATCAGCGCGAGACGATCGCG
GTCTACGGCGCCAAGCCGCCATTGCTGCCGCTCGCCGCCCGTCCGGACGTGCTGGTGTTCGAGACGCCGCCGCTCGCGCG
CGACATCGAGGTCACCGGCCCGATCGAGGCATTGCTGTGGATCTCGTCCAACTGCCCGGACACGGACTTCACGATCAAGC
TGATCGACGTCCATCCGCCGAGCCCGGACGATCCGGAAGGGTTCGCGATGAACCTGACCGCGGGCATCCTGCGCTGCCGC
TATCGCGACAGCTGGGAGCAGCCCAGCCTGATGGAGCCCGGCAAGGTCTATCCGGTCAAGGTCAGCGCGCTGCCGACATC
CAATTTGTTCAAGGCGGGGCATCGCATCCGGCTCGACATCTCGTCGAGCAACTTCCCGCATTTCGACGTCAACCCAAACA
CCGGCGCACCGGAAGGGCGCGGGCTGTCGACGCGGGTCGCCACCAACACCGTGTTCGTGGATTCGTCCCGTCCGTCGCAC
GTGGTGCTGCCGATCATTCCCGAGCAGGAGCCGCAGTGA

Upstream 100 bases:

>100_bases
CCGAATCGCGCAGCCAGATCGTGCTGCAGAAATATCCCAGGAATGCTTGAACCTGGTGACGGACTGTCGCAAACGCAGTC
GCCGAACGAGGAGAGCGTAA

Downstream 100 bases:

>100_bases
CGGCAGGATGCGCCAGCCGGTCGATGAGCGACGAGGGCCGCTCACCAATGACGGTCAGCCACCCGCTGATCAGCCGCTAA
CCGCCGCTTCATGCTGCGCA

Product: aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 652

Protein sequence:

>652_residues
MIELDRLSRRRFVQGMATLGAVGAAPALGATETPASDMLVDKGIMVAMRDGVHLATDIYWPASGGKRLDGRLPVIMNRTP
YGREKTAAREMTADGRRRTRAEVAGYYVRRGYAFIYQDTRGRGGSEGQFVKYLDDGHDGFDMCQWIVAQPWSDGRIGMLG
TSYDAHTQAAAACAGAPGLKAVFLDFGGFSNAYQSGIRQGGAFELKQVTWAYNLGLDSPELARDPVRLAALKAVDLKAWF
ASMPWKRGHTPISLIPDYEDYVFEQWQHGSFDGYWKRLGIYAAGFYPQLARSATVHLSGWYDPYSRTATDNFTGTRQQAL
QPARLILGPWTHGARSTTFAGDVDFGPEATFEHATGQDYFAYRLAYFDRHLRGLENSDREQPPVRIFVMGGGSGRRNAEG
RLEHGGRWRSEADWPIPRTRWTRFYCHASGALAESLPEADSEALSYDFDPRDPVPTIGGAVTSGEPLMRGGAFDQRETIA
VYGAKPPLLPLAARPDVLVFETPPLARDIEVTGPIEALLWISSNCPDTDFTIKLIDVHPPSPDDPEGFAMNLTAGILRCR
YRDSWEQPSLMEPGKVYPVKVSALPTSNLFKAGHRIRLDISSSNFPHFDVNPNTGAPEGRGLSTRVATNTVFVDSSRPSH
VVLPIIPEQEPQ

Sequences:

>Translated_652_residues
MIELDRLSRRRFVQGMATLGAVGAAPALGATETPASDMLVDKGIMVAMRDGVHLATDIYWPASGGKRLDGRLPVIMNRTP
YGREKTAAREMTADGRRRTRAEVAGYYVRRGYAFIYQDTRGRGGSEGQFVKYLDDGHDGFDMCQWIVAQPWSDGRIGMLG
TSYDAHTQAAAACAGAPGLKAVFLDFGGFSNAYQSGIRQGGAFELKQVTWAYNLGLDSPELARDPVRLAALKAVDLKAWF
ASMPWKRGHTPISLIPDYEDYVFEQWQHGSFDGYWKRLGIYAAGFYPQLARSATVHLSGWYDPYSRTATDNFTGTRQQAL
QPARLILGPWTHGARSTTFAGDVDFGPEATFEHATGQDYFAYRLAYFDRHLRGLENSDREQPPVRIFVMGGGSGRRNAEG
RLEHGGRWRSEADWPIPRTRWTRFYCHASGALAESLPEADSEALSYDFDPRDPVPTIGGAVTSGEPLMRGGAFDQRETIA
VYGAKPPLLPLAARPDVLVFETPPLARDIEVTGPIEALLWISSNCPDTDFTIKLIDVHPPSPDDPEGFAMNLTAGILRCR
YRDSWEQPSLMEPGKVYPVKVSALPTSNLFKAGHRIRLDISSSNFPHFDVNPNTGAPEGRGLSTRVATNTVFVDSSRPSH
VVLPIIPEQEPQ
>Mature_652_residues
MIELDRLSRRRFVQGMATLGAVGAAPALGATETPASDMLVDKGIMVAMRDGVHLATDIYWPASGGKRLDGRLPVIMNRTP
YGREKTAAREMTADGRRRTRAEVAGYYVRRGYAFIYQDTRGRGGSEGQFVKYLDDGHDGFDMCQWIVAQPWSDGRIGMLG
TSYDAHTQAAAACAGAPGLKAVFLDFGGFSNAYQSGIRQGGAFELKQVTWAYNLGLDSPELARDPVRLAALKAVDLKAWF
ASMPWKRGHTPISLIPDYEDYVFEQWQHGSFDGYWKRLGIYAAGFYPQLARSATVHLSGWYDPYSRTATDNFTGTRQQAL
QPARLILGPWTHGARSTTFAGDVDFGPEATFEHATGQDYFAYRLAYFDRHLRGLENSDREQPPVRIFVMGGGSGRRNAEG
RLEHGGRWRSEADWPIPRTRWTRFYCHASGALAESLPEADSEALSYDFDPRDPVPTIGGAVTSGEPLMRGGAFDQRETIA
VYGAKPPLLPLAARPDVLVFETPPLARDIEVTGPIEALLWISSNCPDTDFTIKLIDVHPPSPDDPEGFAMNLTAGILRCR
YRDSWEQPSLMEPGKVYPVKVSALPTSNLFKAGHRIRLDISSSNFPHFDVNPNTGAPEGRGLSTRVATNTVFVDSSRPSH
VVLPIIPEQEPQ

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 71959; Mature: 71959

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELDRLSRRRFVQGMATLGAVGAAPALGATETPASDMLVDKGIMVAMRDGVHLATDIYW
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEEEEEECCEEEEEEEEE
PASGGKRLDGRLPVIMNRTPYGREKTAAREMTADGRRRTRAEVAGYYVRRGYAFIYQDTR
ECCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCC
GRGGSEGQFVKYLDDGHDGFDMCQWIVAQPWSDGRIGMLGTSYDAHTQAAAACAGAPGLK
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCE
AVFLDFGGFSNAYQSGIRQGGAFELKQVTWAYNLGLDSPELARDPVRLAALKAVDLKAWF
EEEEECCCCCHHHHHHHCCCCCEEEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHH
ASMPWKRGHTPISLIPDYEDYVFEQWQHGSFDGYWKRLGIYAAGFYPQLARSATVHLSGW
HCCCCCCCCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHEEEECCCHHHHCCEEEEEECC
YDPYSRTATDNFTGTRQQALQPARLILGPWTHGARSTTFAGDVDFGPEATFEHATGQDYF
CCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCHHH
AYRLAYFDRHLRGLENSDREQPPVRIFVMGGGSGRRNAEGRLEHGGRWRSEADWPIPRTR
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
WTRFYCHASGALAESLPEADSEALSYDFDPRDPVPTIGGAVTSGEPLMRGGAFDQRETIA
EEEEEEECCCHHHHHCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEEE
VYGAKPPLLPLAARPDVLVFETPPLARDIEVTGPIEALLWISSNCPDTDFTIKLIDVHPP
EECCCCCCCEECCCCCEEEEECCCCCCCEEECCCEEEEEEECCCCCCCCEEEEEEEECCC
SPDDPEGFAMNLTAGILRCRYRDSWEQPSLMEPGKVYPVKVSALPTSNLFKAGHRIRLDI
CCCCCCCEEEEEHHHHHEECCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCEEEEEE
SSSNFPHFDVNPNTGAPEGRGLSTRVATNTVFVDSSRPSHVVLPIIPEQEPQ
CCCCCCEEECCCCCCCCCCCCCEEEEEEEEEEEECCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MIELDRLSRRRFVQGMATLGAVGAAPALGATETPASDMLVDKGIMVAMRDGVHLATDIYW
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEEEEEECCEEEEEEEEE
PASGGKRLDGRLPVIMNRTPYGREKTAAREMTADGRRRTRAEVAGYYVRRGYAFIYQDTR
ECCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCC
GRGGSEGQFVKYLDDGHDGFDMCQWIVAQPWSDGRIGMLGTSYDAHTQAAAACAGAPGLK
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCE
AVFLDFGGFSNAYQSGIRQGGAFELKQVTWAYNLGLDSPELARDPVRLAALKAVDLKAWF
EEEEECCCCCHHHHHHHCCCCCEEEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHH
ASMPWKRGHTPISLIPDYEDYVFEQWQHGSFDGYWKRLGIYAAGFYPQLARSATVHLSGW
HCCCCCCCCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHEEEECCCHHHHCCEEEEEECC
YDPYSRTATDNFTGTRQQALQPARLILGPWTHGARSTTFAGDVDFGPEATFEHATGQDYF
CCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCHHH
AYRLAYFDRHLRGLENSDREQPPVRIFVMGGGSGRRNAEGRLEHGGRWRSEADWPIPRTR
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
WTRFYCHASGALAESLPEADSEALSYDFDPRDPVPTIGGAVTSGEPLMRGGAFDQRETIA
EEEEEEECCCHHHHHCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEEE
VYGAKPPLLPLAARPDVLVFETPPLARDIEVTGPIEALLWISSNCPDTDFTIKLIDVHPP
EECCCCCCCEECCCCCEEEEECCCCCCCEEECCCEEEEEEECCCCCCCCEEEEEEEECCC
SPDDPEGFAMNLTAGILRCRYRDSWEQPSLMEPGKVYPVKVSALPTSNLFKAGHRIRLDI
CCCCCCCEEEEEHHHHHEECCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCEEEEEE
SSSNFPHFDVNPNTGAPEGRGLSTRVATNTVFVDSSRPSHVVLPIIPEQEPQ
CCCCCCEEECCCCCCCCCCCCCEEEEEEEEEEEECCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]