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The map label for this gene is braD [H]

Identifier: 146337632

GI number: 146337632

Start: 500622

End: 501605

Strand: Reverse

Name: braD [H]

Synonym: BRADO0497

Alternate gene names: 146337632

Gene position: 501605-500622 (Counterclockwise)

Preceding gene: 146337633

Following gene: 146337631

Centisome position: 6.73

GC content: 65.65

Gene sequence:

>984_bases
TTGCCCAAGCCGAAGCGCGACATCGCGCCGTTGCTGCTGCCGGTCGTGCTGGCACTGTTGATGATCCCGCTCGTTGGATC
GACGAGTTCTTGGGTCACCCTGACGGTCGCGAGCCTGGCGATGGGGATGATGATCTTCATCATGGCCTCCGGCTTGACGC
TCGTCTTTGGCCTGATGGACGTTCTGAACTTCGGCCACGGCGCGTTCATTGCCGTCGGCGCGTATGTCGCCACGCTGGTT
CTGCTGCCGCTGGCGAGCTGGGCGCAGGCCGATTCGCTGCTGACCAACCTCGCCGTGCTCGTTCCGGCCGCGCTGCTGTC
GATGGGCGTCACCGGCGCACTCGGCCTCGTGGTCGAACGCGTGCTGGTGCTGCCGGTCTACGGCCAGCACCTCAAGCAGA
TCCTGATGACAACCGGTGGCCTGATCGTCGCCGAGCAGACGCTGTATGCGCTGTTCGGCCCGCAGATCATCCCCATGCCG
CTGCCGGCGGCGCTGCGCGGCTCGTTCATCCTCGGCGATGTCGCGATCTCGAAGTACCGGCTGCTGGCGCTGCTCATCGG
CCTCGTGATCTTCGTCGCCATCGAGCTGGTGCTGAACCGCACCAAGATCGGGCTCCTGATCCGCGCTGGCGTCGAGAATC
GGGAGATGGTCGAGGCGCTCGGCTATCGCATCCGCCGCCTGTTCCTTGGCGTCTTCATGACCGGCTCGGCGCTGGCCGGC
CTCGGCGGCGTGATGTGGGGCCTCTACCGCGAGCAGGTCCATGCCTCGATCGGCGACGAGCTCACCGTGCTGGTCTTCAT
CGTCGTCATCATCGGCGGACTTGGCTCGATCACAGGCTGCTTCATCGGCGCGATCCTGGTCGCGATGGTTGCCAATTACG
GCGGCTTCCTGGTGCCCAAGCTCGCCCTCGTCTCCAACATCCTGCTGATGGTCGCCGTGCTGATGTGGCGGCCGCGCGGC
CTCTATGCGGTGACCAGCCGATGA

Upstream 100 bases:

>100_bases
GCGAGATGGCCGCGCTCGCCGCCGACGTGCCGCTGCAGGAACGCCTGCTCGGCCTCAGCCTGGAGGCGCATCAATGAGCG
ACATCGCGGCTATCGACACG

Downstream 100 bases:

>100_bases
TGATCCTGTCCGGCGATCCGCCCCGCAGCCGCGCGCTGTCGATCCTGCTCGTCGTCATCGTGCTGGCGCTGCTGGCGACG
CCCTTCATCTTCCCCGGAGC

Product: putative branched-chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MPKPKRDIAPLLLPVVLALLMIPLVGSTSSWVTLTVASLAMGMMIFIMASGLTLVFGLMDVLNFGHGAFIAVGAYVATLV
LLPLASWAQADSLLTNLAVLVPAALLSMGVTGALGLVVERVLVLPVYGQHLKQILMTTGGLIVAEQTLYALFGPQIIPMP
LPAALRGSFILGDVAISKYRLLALLIGLVIFVAIELVLNRTKIGLLIRAGVENREMVEALGYRIRRLFLGVFMTGSALAG
LGGVMWGLYREQVHASIGDELTVLVFIVVIIGGLGSITGCFIGAILVAMVANYGGFLVPKLALVSNILLMVAVLMWRPRG
LYAVTSR

Sequences:

>Translated_327_residues
MPKPKRDIAPLLLPVVLALLMIPLVGSTSSWVTLTVASLAMGMMIFIMASGLTLVFGLMDVLNFGHGAFIAVGAYVATLV
LLPLASWAQADSLLTNLAVLVPAALLSMGVTGALGLVVERVLVLPVYGQHLKQILMTTGGLIVAEQTLYALFGPQIIPMP
LPAALRGSFILGDVAISKYRLLALLIGLVIFVAIELVLNRTKIGLLIRAGVENREMVEALGYRIRRLFLGVFMTGSALAG
LGGVMWGLYREQVHASIGDELTVLVFIVVIIGGLGSITGCFIGAILVAMVANYGGFLVPKLALVSNILLMVAVLMWRPRG
LYAVTSR
>Mature_326_residues
PKPKRDIAPLLLPVVLALLMIPLVGSTSSWVTLTVASLAMGMMIFIMASGLTLVFGLMDVLNFGHGAFIAVGAYVATLVL
LPLASWAQADSLLTNLAVLVPAALLSMGVTGALGLVVERVLVLPVYGQHLKQILMTTGGLIVAEQTLYALFGPQIIPMPL
PAALRGSFILGDVAISKYRLLALLIGLVIFVAIELVLNRTKIGLLIRAGVENREMVEALGYRIRRLFLGVFMTGSALAGL
GGVMWGLYREQVHASIGDELTVLVFIVVIIGGLGSITGCFIGAILVAMVANYGGFLVPKLALVSNILLMVAVLMWRPRGL
YAVTSR

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 34660; Mature: 34529

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPKRDIAPLLLPVVLALLMIPLVGSTSSWVTLTVASLAMGMMIFIMASGLTLVFGLMD
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLNFGHGAFIAVGAYVATLVLLPLASWAQADSLLTNLAVLVPAALLSMGVTGALGLVVER
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
VLVLPVYGQHLKQILMTTGGLIVAEQTLYALFGPQIIPMPLPAALRGSFILGDVAISKYR
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHH
LLALLIGLVIFVAIELVLNRTKIGLLIRAGVENREMVEALGYRIRRLFLGVFMTGSALAG
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGVMWGLYREQVHASIGDELTVLVFIVVIIGGLGSITGCFIGAILVAMVANYGGFLVPK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHH
LALVSNILLMVAVLMWRPRGLYAVTSR
HHHHHHHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure 
PKPKRDIAPLLLPVVLALLMIPLVGSTSSWVTLTVASLAMGMMIFIMASGLTLVFGLMD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLNFGHGAFIAVGAYVATLVLLPLASWAQADSLLTNLAVLVPAALLSMGVTGALGLVVER
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
VLVLPVYGQHLKQILMTTGGLIVAEQTLYALFGPQIIPMPLPAALRGSFILGDVAISKYR
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHH
LLALLIGLVIFVAIELVLNRTKIGLLIRAGVENREMVEALGYRIRRLFLGVFMTGSALAG
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGVMWGLYREQVHASIGDELTVLVFIVVIIGGLGSITGCFIGAILVAMVANYGGFLVPK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHH
LALVSNILLMVAVLMWRPRGLYAVTSR
HHHHHHHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]