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The map label for this gene is atpD [H]

Identifier: 146337564

GI number: 146337564

Start: 429266

End: 430708

Strand: Direct

Name: atpD [H]

Synonym: BRADO0419

Alternate gene names: 146337564

Gene position: 429266-430708 (Clockwise)

Preceding gene: 146337563

Following gene: 146337565

Centisome position: 5.76

GC content: 65.9

Gene sequence:

>1443_bases
ATGGCTACCGCAGCCAACCAGATCGGTCGCGTCACCCAGGTGATCGGCGCTGTCGTCGACGTTCAGTTCGAAGGTCACCT
GCCCGCAATTCTCAACTCGCTGGAAACGAAGAACGGCGGCAACCGCCTCGTGCTCGAGGTCGCGCAGCATCTCGGTGAAT
CCACCGTGCGCGCGATCGCGATGGACACGACCGAAGGTCTGGTCCGTGGCCAGGAAGTGACCGACACCGGCGCTCCGATC
CGCGTTCCCGTCGGCGAAGGCACGCTCGGCCGCATCATCAACGTGATCGGCGAGCCGATCGACGAAGCCGGCCCGGTGAA
GGCCGACAACGTCCGCGCCATTCACCAGGAAGCGCCGACCTACACCGACCAGTCGACCGAGGCCGAGATCCTCGTGACCG
GCATCAAGGTCGTCGACCTGCTCGCCCCCTACGCCAAGGGCGGCAAGATCGGTCTGTTCGGCGGCGCCGGCGTCGGCAAG
ACCGTGCTGATTCAGGAGCTGATCAACAACGTCGCCAAGGCACACGGCGGCTACTCGGTGTTCGCCGGCGTCGGTGAGCG
CACCCGCGAGGGCAACGACCTCTATCACGAGTTCATCGAGTCCAAGGTCAATGCCGATCCGCACAACCCGGATCCGAGCG
TGAAGTCGAAGTGCGCGCTGGTGTTCGGCCAGATGAACGAGCCGCCGGGCGCCCGCGCCCGCGTCGCGCTCACCGGTCTG
ACCATCGCGGAAGACTTCCGCGACAAGGGCCAGGACGTGCTGTTCTTCGTCGACAACATCTTCCGCTTCACCCAGGCCGG
CTCGGAAGTGTCGGCGCTGCTCGGCCGTATTCCTTCGGCGGTGGGTTATCAGCCGACGCTCGCCACCGACATGGGCGCGC
TGCAGGAGCGCATCACCACCACCACCAAGGGCTCGATCACCTCGGTGCAGGCCATCTACGTGCCGGCCGACGACTTGACC
GACCCGGCCCCGGCGACGTCGTTCGCGCACTTGGACGCGACCACGACGCTGTCGCGCTCGATCGCCGAAAAGGGCATCTA
CCCGGCCGTCGACCCGCTCGACTCGACGTCGCGCATGCTCTCCCCGCTGGTCGTCGGCGAGGAGCACTATGCGGTCGCCC
GCCAGGTGCAGCAGGTGCTTCAGCGCTACAAGGCGCTGCAGGACATCATCGCCATCCTGGGCATGGACGAGCTCTCGGAA
GAGGACAAGCTGACTGTCGCGCGCGCCCGCAAGGTCGAGCGCTTCATGTCGCAGCCGTTCCACGTCGCCGAAATCTTCAC
GGGATCGCCGGGCAAGTTCGTCGAGCTCGCCGACACCATCAAGGGCTTCAAGGGCCTGGTGGAAGGCAAGTACGACCACC
TGCCGGAGGCTGCCTTCTACATGGTCGGCACCATCGAAGAGGCGGTCGAGAAGGGCAAGAAGCTGGCGGCGGAAGCCGCC
TAA

Upstream 100 bases:

>100_bases
AGGCGGTCTAACCGCGCAGCGCCCGCTGGAAGAAAATACGTTCAAGTTTCGCGGTCCCACGGACTGCGCCTGAAATTCGG
ATCGTAAGGAGAGAGATGAG

Downstream 100 bases:

>100_bases
GAGGCGAATAGCGAAGCGGGAGTAGCGAATAGAACGATCTCATTCGCTGCTCCCTTCCTCCCTACTCGCTGTTCGCTATC
CGCTATTCGCAGGTTTCCTC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta 1; F-ATPase subunit beta 1 [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MATAANQIGRVTQVIGAVVDVQFEGHLPAILNSLETKNGGNRLVLEVAQHLGESTVRAIAMDTTEGLVRGQEVTDTGAPI
RVPVGEGTLGRIINVIGEPIDEAGPVKADNVRAIHQEAPTYTDQSTEAEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGK
TVLIQELINNVAKAHGGYSVFAGVGERTREGNDLYHEFIESKVNADPHNPDPSVKSKCALVFGQMNEPPGARARVALTGL
TIAEDFRDKGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTTKGSITSVQAIYVPADDLT
DPAPATSFAHLDATTTLSRSIAEKGIYPAVDPLDSTSRMLSPLVVGEEHYAVARQVQQVLQRYKALQDIIAILGMDELSE
EDKLTVARARKVERFMSQPFHVAEIFTGSPGKFVELADTIKGFKGLVEGKYDHLPEAAFYMVGTIEEAVEKGKKLAAEAA

Sequences:

>Translated_480_residues
MATAANQIGRVTQVIGAVVDVQFEGHLPAILNSLETKNGGNRLVLEVAQHLGESTVRAIAMDTTEGLVRGQEVTDTGAPI
RVPVGEGTLGRIINVIGEPIDEAGPVKADNVRAIHQEAPTYTDQSTEAEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGK
TVLIQELINNVAKAHGGYSVFAGVGERTREGNDLYHEFIESKVNADPHNPDPSVKSKCALVFGQMNEPPGARARVALTGL
TIAEDFRDKGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTTKGSITSVQAIYVPADDLT
DPAPATSFAHLDATTTLSRSIAEKGIYPAVDPLDSTSRMLSPLVVGEEHYAVARQVQQVLQRYKALQDIIAILGMDELSE
EDKLTVARARKVERFMSQPFHVAEIFTGSPGKFVELADTIKGFKGLVEGKYDHLPEAAFYMVGTIEEAVEKGKKLAAEAA
>Mature_479_residues
ATAANQIGRVTQVIGAVVDVQFEGHLPAILNSLETKNGGNRLVLEVAQHLGESTVRAIAMDTTEGLVRGQEVTDTGAPIR
VPVGEGTLGRIINVIGEPIDEAGPVKADNVRAIHQEAPTYTDQSTEAEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKT
VLIQELINNVAKAHGGYSVFAGVGERTREGNDLYHEFIESKVNADPHNPDPSVKSKCALVFGQMNEPPGARARVALTGLT
IAEDFRDKGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTTKGSITSVQAIYVPADDLTD
PAPATSFAHLDATTTLSRSIAEKGIYPAVDPLDSTSRMLSPLVVGEEHYAVARQVQQVLQRYKALQDIIAILGMDELSEE
DKLTVARARKVERFMSQPFHVAEIFTGSPGKFVELADTIKGFKGLVEGKYDHLPEAAFYMVGTIEEAVEKGKKLAAEAA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=472, Percent_Identity=77.5423728813559, Blast_Score=726, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=304, Percent_Identity=27.9605263157895, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI19913428, Length=372, Percent_Identity=26.3440860215054, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI19913426, Length=372, Percent_Identity=25.5376344086022, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI50345984, Length=301, Percent_Identity=25.9136212624585, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4757810, Length=301, Percent_Identity=25.9136212624585, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1790170, Length=468, Percent_Identity=68.1623931623932, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=334, Percent_Identity=31.437125748503, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790172, Length=336, Percent_Identity=27.0833333333333, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=478, Percent_Identity=74.0585774058577, Blast_Score=711, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=338, Percent_Identity=27.5147928994083, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17570191, Length=360, Percent_Identity=26.1111111111111, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17510931, Length=360, Percent_Identity=25.8333333333333, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71988080, Length=324, Percent_Identity=24.6913580246914, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71988063, Length=324, Percent_Identity=24.6913580246914, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71988074, Length=276, Percent_Identity=23.5507246376812, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322581, Length=474, Percent_Identity=74.4725738396624, Blast_Score=696, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=371, Percent_Identity=26.4150943396226, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319370, Length=375, Percent_Identity=26.1333333333333, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320016, Length=252, Percent_Identity=25, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24638766, Length=473, Percent_Identity=77.3784355179704, Blast_Score=731, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=471, Percent_Identity=70.9129511677282, Blast_Score=664, Evalue=0.0,
Organism=Drosophila melanogaster, GI24638768, Length=90, Percent_Identity=73.3333333333333, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI20129479, Length=303, Percent_Identity=28.3828382838284, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24583988, Length=321, Percent_Identity=27.7258566978193, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583986, Length=321, Percent_Identity=27.7258566978193, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583984, Length=321, Percent_Identity=27.7258566978193, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583992, Length=304, Percent_Identity=27.9605263157895, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281361666, Length=371, Percent_Identity=26.9541778975741, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24646341, Length=371, Percent_Identity=26.9541778975741, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17136796, Length=371, Percent_Identity=26.9541778975741, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24658560, Length=302, Percent_Identity=25.8278145695364, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 51229; Mature: 51098

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAANQIGRVTQVIGAVVDVQFEGHLPAILNSLETKNGGNRLVLEVAQHLGESTVRAIA
CCCCHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHE
MDTTEGLVRGQEVTDTGAPIRVPVGEGTLGRIINVIGEPIDEAGPVKADNVRAIHQEAPT
ECCHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCC
YTDQSTEAEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIQELINNVAKAHGGYSV
CCCCCCCCEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEE
FAGVGERTREGNDLYHEFIESKVNADPHNPDPSVKSKCALVFGQMNEPPGARARVALTGL
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHEEECCCCCCCCCEEEEEECC
TIAEDFRDKGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITT
HHHHHHHHCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHC
TTKGSITSVQAIYVPADDLTDPAPATSFAHLDATTTLSRSIAEKGIYPAVDPLDSTSRML
CCCCCCEEEEEEEECCCCCCCCCCCCCCHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
SPLVVGEEHYAVARQVQQVLQRYKALQDIIAILGMDELSEEDKLTVARARKVERFMSQPF
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCC
HVAEIFTGSPGKFVELADTIKGFKGLVEGKYDHLPEAAFYMVGTIEEAVEKGKKLAAEAA
EEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATAANQIGRVTQVIGAVVDVQFEGHLPAILNSLETKNGGNRLVLEVAQHLGESTVRAIA
CCCHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHE
MDTTEGLVRGQEVTDTGAPIRVPVGEGTLGRIINVIGEPIDEAGPVKADNVRAIHQEAPT
ECCHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCC
YTDQSTEAEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIQELINNVAKAHGGYSV
CCCCCCCCEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEE
FAGVGERTREGNDLYHEFIESKVNADPHNPDPSVKSKCALVFGQMNEPPGARARVALTGL
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHEEECCCCCCCCCEEEEEECC
TIAEDFRDKGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITT
HHHHHHHHCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHC
TTKGSITSVQAIYVPADDLTDPAPATSFAHLDATTTLSRSIAEKGIYPAVDPLDSTSRML
CCCCCCEEEEEEEECCCCCCCCCCCCCCHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
SPLVVGEEHYAVARQVQQVLQRYKALQDIIAILGMDELSEEDKLTVARARKVERFMSQPF
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCC
HVAEIFTGSPGKFVELADTIKGFKGLVEGKYDHLPEAAFYMVGTIEEAVEKGKKLAAEAA
EEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA