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The map label for this gene is ccmG [H]

Identifier: 146337534

GI number: 146337534

Start: 393582

End: 394178

Strand: Reverse

Name: ccmG [H]

Synonym: BRADO0388

Alternate gene names: 146337534

Gene position: 394178-393582 (Counterclockwise)

Preceding gene: 146337535

Following gene: 146337531

Centisome position: 5.29

GC content: 69.18

Gene sequence:

>597_bases
ATGACCGACCAGACCGCCCCCGAGGCCGCGCCGCGACGGCGCTCGCTGTTGATGCTGCTGCCGCTCGTGGTGTTTCTCGG
GCTGGCGGCGCTGTTCTGGTTTCGGCTCGGCAATGGCGACCCCTCGCGGATTCCCTCGGCGCTGATCGGCCGCCCCGCGC
CAGCCACGCCGCTGCCGCCGCTGCCCGAGCTCGCGAGGGACGGCGCCGTCATTCCGGGACTCGACCCGGCCGCGCTGAAG
GGCAAGGTCAGCATCGTCAACGTCTGGGCTTCGTGGTGCGTGCCCTGCCATGACGAGGCGCCGCTGCTGGTCGATCTCGG
CCGCGACAAGCGCTTTCAGATCATCGGCATCAACTACAAGGACGCCGCCGACAACGCCCGCCGCTTCCTCGGCCGCTACG
GCAATCCCTACGATTTCGTCGGCGTCGACGGCAACGGCCGCGCCGGCATCGAATGGGGCGTCTACGGCGTGCCGGAGACG
TTCGTGGTGGGGCGCGAGGGCACCATCGTCTACAAGCTGGTCGGCCCGATCACGGCGCAGAACATCGACGCGGTGCTGAA
GCCGGAAATCGAGAAGGCACTGAAGGCGGGGGGTTAG

Upstream 100 bases:

>100_bases
CCTGGATCGCGATCGACTACCGCACCCAGAAGGCGCGGCTGCGCGCGCTCGAGGACAGCGGCATCAGCCGCCGCTCCGGC
CGCGCCGCCACGGACATGCA

Downstream 100 bases:

>100_bases
TCGGCTGGATGCGAGCCAATAAATTGCTCGTCATTTCGAGCAAGCTGTCCGTCCACCCCCGCTGTCATCGCCCGGCTTGA
CCGGGCGATCCAGTACGCCG

Product: periplasmic thioredoxin

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CycY [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTDQTAPEAAPRRRSLLMLLPLVVFLGLAALFWFRLGNGDPSRIPSALIGRPAPATPLPPLPELARDGAVIPGLDPAALK
GKVSIVNVWASWCVPCHDEAPLLVDLGRDKRFQIIGINYKDAADNARRFLGRYGNPYDFVGVDGNGRAGIEWGVYGVPET
FVVGREGTIVYKLVGPITAQNIDAVLKPEIEKALKAGG

Sequences:

>Translated_198_residues
MTDQTAPEAAPRRRSLLMLLPLVVFLGLAALFWFRLGNGDPSRIPSALIGRPAPATPLPPLPELARDGAVIPGLDPAALK
GKVSIVNVWASWCVPCHDEAPLLVDLGRDKRFQIIGINYKDAADNARRFLGRYGNPYDFVGVDGNGRAGIEWGVYGVPET
FVVGREGTIVYKLVGPITAQNIDAVLKPEIEKALKAGG
>Mature_197_residues
TDQTAPEAAPRRRSLLMLLPLVVFLGLAALFWFRLGNGDPSRIPSALIGRPAPATPLPPLPELARDGAVIPGLDPAALKG
KVSIVNVWASWCVPCHDEAPLLVDLGRDKRFQIIGINYKDAADNARRFLGRYGNPYDFVGVDGNGRAGIEWGVYGVPETF
VVGREGTIVYKLVGPITAQNIDAVLKPEIEKALKAGG

Specific function: Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur [

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=186, Percent_Identity=35.4838709677419, Blast_Score=106, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21263; Mature: 21132

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQTAPEAAPRRRSLLMLLPLVVFLGLAALFWFRLGNGDPSRIPSALIGRPAPATPLPP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCCCCCCCC
LPELARDGAVIPGLDPAALKGKVSIVNVWASWCVPCHDEAPLLVDLGRDKRFQIIGINYK
CHHHHHCCCCCCCCCHHHHCCCEEEEEEHHHHCCCCCCCCCEEEECCCCCEEEEEECCCC
DAADNARRFLGRYGNPYDFVGVDGNGRAGIEWGVYGVPETFVVGREGTIVYKLVGPITAQ
CHHHHHHHHHHCCCCCCEEEEECCCCCCCCEECCCCCCCEEEECCCCCEEEEEECCCCCC
NIDAVLKPEIEKALKAGG
CCCHHCCHHHHHHHHCCC
>Mature Secondary Structure 
TDQTAPEAAPRRRSLLMLLPLVVFLGLAALFWFRLGNGDPSRIPSALIGRPAPATPLPP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCCCCCCCC
LPELARDGAVIPGLDPAALKGKVSIVNVWASWCVPCHDEAPLLVDLGRDKRFQIIGINYK
CHHHHHCCCCCCCCCHHHHCCCEEEEEEHHHHCCCCCCCCCEEEECCCCCEEEEEECCCC
DAADNARRFLGRYGNPYDFVGVDGNGRAGIEWGVYGVPETFVVGREGTIVYKLVGPITAQ
CHHHHHHHHHHCCCCCCEEEEECCCCCCCCEECCCCCCCEEEECCCCCEEEEEECCCCCC
NIDAVLKPEIEKALKAGG
CCCHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]