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The map label for this gene is hslV [H]

Identifier: 146337378

GI number: 146337378

Start: 224366

End: 224926

Strand: Reverse

Name: hslV [H]

Synonym: BRADO0211

Alternate gene names: 146337378

Gene position: 224926-224366 (Counterclockwise)

Preceding gene: 146337386

Following gene: 146337377

Centisome position: 3.02

GC content: 67.2

Gene sequence:

>561_bases
ATGCACGCATTGTCCCAAGAGCCCACCGTCTGGCACGGCACCACGATCCTGACCGTCCGCAAGGGGGGCAGGGTGGTCGT
GGGCGGCGACGGCCAGGTCTCGATCGGCCAGACCGTGATCAAGTCCAACGCCCGCAAGGTGCGCAAGCTCGGCAAGGGCG
ACGTCATCGGCGGCTTCGCCGGCGCCACGGCCGACGCTTTCACCCTGTTCGAGCGGCTGGAGAGCAAGCTGGAGCAGTAT
CCGGGGCAATTGACCCGGGCCGCCGTCGAGCTCGCCAAGGACTGGCGGACCGACCGCTATTTGCGCCGGCTGGAAGCGAT
GATGATCGTGGCCGACAAGGAGGTCTCGCTCGTCCTGACCGGCACTGGCGACGTGCTGGAACCGGAAGCGGGCGTGATGG
CGATCGGCTCGGGCGGCAATTACGCGCTGGCGGCGGCGCGGGCGCTGATCGACACCGACAAGGACGCCGAGAGTATCGTG
CGCAAGTCGCTCGACATCGCCGCGGACATCTGCGTCTACACCAACCGCAACATCACCATCGAAGCGCTGTCGGCCGAGTA
G

Upstream 100 bases:

>100_bases
TGGTGAGCGGATTTCAAGACCCGCCGGGGCAGGGCAGGGACCCGGTAATTGTATCCCCCGGCGCGAGGCCCTAAATGAGG
GCACCAACCAAGGACCTCCC

Downstream 100 bases:

>100_bases
ACGATGGCCGCGGACGGGATCAGCATCGCGTCCCGCCGCTCGTCCGGGCTTTGGCTCGGGCTGGTGCTTGCGTTGCTGGC
TCTGCAGGCCGCGATCCTGT

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MHALSQEPTVWHGTTILTVRKGGRVVVGGDGQVSIGQTVIKSNARKVRKLGKGDVIGGFAGATADAFTLFERLESKLEQY
PGQLTRAAVELAKDWRTDRYLRRLEAMMIVADKEVSLVLTGTGDVLEPEAGVMAIGSGGNYALAAARALIDTDKDAESIV
RKSLDIAADICVYTNRNITIEALSAE

Sequences:

>Translated_186_residues
MHALSQEPTVWHGTTILTVRKGGRVVVGGDGQVSIGQTVIKSNARKVRKLGKGDVIGGFAGATADAFTLFERLESKLEQY
PGQLTRAAVELAKDWRTDRYLRRLEAMMIVADKEVSLVLTGTGDVLEPEAGVMAIGSGGNYALAAARALIDTDKDAESIV
RKSLDIAADICVYTNRNITIEALSAE
>Mature_186_residues
MHALSQEPTVWHGTTILTVRKGGRVVVGGDGQVSIGQTVIKSNARKVRKLGKGDVIGGFAGATADAFTLFERLESKLEQY
PGQLTRAAVELAKDWRTDRYLRRLEAMMIVADKEVSLVLTGTGDVLEPEAGVMAIGSGGNYALAAARALIDTDKDAESIV
RKSLDIAADICVYTNRNITIEALSAE

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=172, Percent_Identity=61.046511627907, Blast_Score=211, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 19903; Mature: 19903

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHALSQEPTVWHGTTILTVRKGGRVVVGGDGQVSIGQTVIKSNARKVRKLGKGDVIGGFA
CCCCCCCCCEEECEEEEEEECCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCEECCCC
GATADAFTLFERLESKLEQYPGQLTRAAVELAKDWRTDRYLRRLEAMMIVADKEVSLVLT
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCEEEEEE
GTGDVLEPEAGVMAIGSGGNYALAAARALIDTDKDAESIVRKSLDIAADICVYTNRNITI
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEEECCCEEE
EALSAE
EEECCC
>Mature Secondary Structure
MHALSQEPTVWHGTTILTVRKGGRVVVGGDGQVSIGQTVIKSNARKVRKLGKGDVIGGFA
CCCCCCCCCEEECEEEEEEECCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCEECCCC
GATADAFTLFERLESKLEQYPGQLTRAAVELAKDWRTDRYLRRLEAMMIVADKEVSLVLT
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCEEEEEE
GTGDVLEPEAGVMAIGSGGNYALAAARALIDTDKDAESIVRKSLDIAADICVYTNRNITI
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEEECCCEEE
EALSAE
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA