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The map label for this gene is cph1 [H]

Identifier: 146301749

GI number: 146301749

Start: 4792839

End: 4794095

Strand: Direct

Name: cph1 [H]

Synonym: Fjoh_4011

Alternate gene names: 146301749

Gene position: 4792839-4794095 (Clockwise)

Preceding gene: 146301748

Following gene: 146301750

Centisome position: 78.61

GC content: 38.11

Gene sequence:

>1257_bases
TTGAAGAGCAAAGAAATAAATATAGAATCATTACTCGCAGAAATAGAATCATTAAAGGAAGAACTTTATGAATCTAACAG
CATCGTCAATGCCATAAAACAAGGAGATGTAGATGCTTTGGTAGTGAATAACAATGGAGTTCCTGAACTTTATTCTCTGG
AAACGGCAGATTATACGTACCGTCTTCTTATAGAAAAGTTCCGGCAGGGTGCGCTTAGTATTTCGCGCAACGGACTCATA
TTGTATTGCAACGACTATTTTTCAGAACTGGTCGGCATTCCTTCAGAGCAGATTATAGGGACGTATTTAAACGAATATTT
TGATAATCCCACGCAGTTTGTACAGATTATTCAGGCGCTTCGATACGGAATCGCCACACACGAAATCTTTTTTAAATCCA
ATAACGAAAAAAAAACTTTTCCGGCTTATATCGCCTTAACCGATCTCGAACCCTCCGTAGAAGCCATTGGAATCGTAATT
ACAGATTTAACCGAAAAGAAAAAACACGAAGAAGCTTTAATTCGTCATCAAGAAGAATTAGAAGAAAAAATCAAAGAGTT
AAACCGAATCAACACCAATCTCGAAGAGTTTATTCACGTAATCTCGCACGATTTAAAAGAACCGCTCCGAAAAATTGTAA
TGCACAATGACAGAATCGACGGAAGTTATCTTTCTGAAACCGATGCCAAATCAATGAACGTTCTAAAATCATCGGCCTTG
CGATTGAATTCACTGGTTGATGATTTGGTGCAGTATTCGTCGCACACCGCGCAGGAAGAACGAACCGAAATTAATCTCGC
TTCGATAATTGCCGAAGTCATCGAAGATCTCGAAATTATAATTACCGATAAAAAAGCCGAAATTCAAATAGGAAAACTTC
CCGCCATAAAAGCCTCTAAAGTTCAAATCCGCCAGCTTTTTGGCAACCTCATTACCAACGCCATAAAATACAGCAAAGAA
GCCGTTGCGCCGTTTATAGAAATTTACCAGGCCGAAAATTTAAATGTTGAAATGCCAAATCAAAATGCTAAATTTGTAAA
GATTCAAATAAAAGACAACGGAATTGGCATGGAGTCGAGCCATCTTCTTAAAATCTTTACCATTTTTCAGCGCCTTCACG
CCCGAAACGAATATTCAGGAAACGGAATTGGCCTTGCAATTTGTAAAAAAATTATGGAAAACCACTCCGGAAACATAACC
GTCGAAAGCACGCTCAACGAAGGCACAACATTTAATCTTTACTTTCCAATTGTATAA

Upstream 100 bases:

>100_bases
CCAACATTAATCAAAGTTTATCCAGAACCCAAAAGAATCATACTGGGAGATCTGTCAGATAAAGAAAAGGTTTTATATAT
ACTAAATATAGGCGCATAGT

Downstream 100 bases:

>100_bases
AATGCCACAAAAAAACAACCTGCATATCATAATCGCAGAAGATGACTTTGATGACGCTGACGTTATCTGCGAAACCTTCA
ACCAAAACCCCAATTTTGGC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKSKEINIESLLAEIESLKEELYESNSIVNAIKQGDVDALVVNNNGVPELYSLETADYTYRLLIEKFRQGALSISRNGLI
LYCNDYFSELVGIPSEQIIGTYLNEYFDNPTQFVQIIQALRYGIATHEIFFKSNNEKKTFPAYIALTDLEPSVEAIGIVI
TDLTEKKKHEEALIRHQEELEEKIKELNRINTNLEEFIHVISHDLKEPLRKIVMHNDRIDGSYLSETDAKSMNVLKSSAL
RLNSLVDDLVQYSSHTAQEERTEINLASIIAEVIEDLEIIITDKKAEIQIGKLPAIKASKVQIRQLFGNLITNAIKYSKE
AVAPFIEIYQAENLNVEMPNQNAKFVKIQIKDNGIGMESSHLLKIFTIFQRLHARNEYSGNGIGLAICKKIMENHSGNIT
VESTLNEGTTFNLYFPIV

Sequences:

>Translated_418_residues
MKSKEINIESLLAEIESLKEELYESNSIVNAIKQGDVDALVVNNNGVPELYSLETADYTYRLLIEKFRQGALSISRNGLI
LYCNDYFSELVGIPSEQIIGTYLNEYFDNPTQFVQIIQALRYGIATHEIFFKSNNEKKTFPAYIALTDLEPSVEAIGIVI
TDLTEKKKHEEALIRHQEELEEKIKELNRINTNLEEFIHVISHDLKEPLRKIVMHNDRIDGSYLSETDAKSMNVLKSSAL
RLNSLVDDLVQYSSHTAQEERTEINLASIIAEVIEDLEIIITDKKAEIQIGKLPAIKASKVQIRQLFGNLITNAIKYSKE
AVAPFIEIYQAENLNVEMPNQNAKFVKIQIKDNGIGMESSHLLKIFTIFQRLHARNEYSGNGIGLAICKKIMENHSGNIT
VESTLNEGTTFNLYFPIV
>Mature_418_residues
MKSKEINIESLLAEIESLKEELYESNSIVNAIKQGDVDALVVNNNGVPELYSLETADYTYRLLIEKFRQGALSISRNGLI
LYCNDYFSELVGIPSEQIIGTYLNEYFDNPTQFVQIIQALRYGIATHEIFFKSNNEKKTFPAYIALTDLEPSVEAIGIVI
TDLTEKKKHEEALIRHQEELEEKIKELNRINTNLEEFIHVISHDLKEPLRKIVMHNDRIDGSYLSETDAKSMNVLKSSAL
RLNSLVDDLVQYSSHTAQEERTEINLASIIAEVIEDLEIIITDKKAEIQIGKLPAIKASKVQIRQLFGNLITNAIKYSKE
AVAPFIEIYQAENLNVEMPNQNAKFVKIQIKDNGIGMESSHLLKIFTIFQRLHARNEYSGNGIGLAICKKIMENHSGNIT
VESTLNEGTTFNLYFPIV

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=264, Percent_Identity=24.2424242424242, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788549, Length=377, Percent_Identity=23.342175066313, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1789149, Length=311, Percent_Identity=23.7942122186495, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=269, Percent_Identity=20.0743494423792, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=291, Percent_Identity=22.3367697594502, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=279, Percent_Identity=24.7311827956989, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=26.3565891472868, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786600, Length=375, Percent_Identity=22.1333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=25.4826254826255, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786783, Length=254, Percent_Identity=22.8346456692913, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47430; Mature: 47430

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKEINIESLLAEIESLKEELYESNSIVNAIKQGDVDALVVNNNGVPELYSLETADYTY
CCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCHHH
RLLIEKFRQGALSISRNGLILYCNDYFSELVGIPSEQIIGTYLNEYFDNPTQFVQIIQAL
HHHHHHHHHCCCEECCCCEEEEECHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
RYGIATHEIFFKSNNEKKTFPAYIALTDLEPSVEAIGIVITDLTEKKKHEEALIRHQEEL
HHCCHHEEEEEECCCCCCCCCEEEEEECCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHH
EEKIKELNRINTNLEEFIHVISHDLKEPLRKIVMHNDRIDGSYLSETDAKSMNVLKSSAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
RLNSLVDDLVQYSSHTAQEERTEINLASIIAEVIEDLEIIITDKKAEIQIGKLPAIKASK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCHHH
VQIRQLFGNLITNAIKYSKEAVAPFIEIYQAENLNVEMPNQNAKFVKIQIKDNGIGMESS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEEEEECCCCCCCHH
HLLKIFTIFQRLHARNEYSGNGIGLAICKKIMENHSGNITVESTLNEGTTFNLYFPIV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCC
>Mature Secondary Structure
MKSKEINIESLLAEIESLKEELYESNSIVNAIKQGDVDALVVNNNGVPELYSLETADYTY
CCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCHHH
RLLIEKFRQGALSISRNGLILYCNDYFSELVGIPSEQIIGTYLNEYFDNPTQFVQIIQAL
HHHHHHHHHCCCEECCCCEEEEECHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
RYGIATHEIFFKSNNEKKTFPAYIALTDLEPSVEAIGIVITDLTEKKKHEEALIRHQEEL
HHCCHHEEEEEECCCCCCCCCEEEEEECCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHH
EEKIKELNRINTNLEEFIHVISHDLKEPLRKIVMHNDRIDGSYLSETDAKSMNVLKSSAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
RLNSLVDDLVQYSSHTAQEERTEINLASIIAEVIEDLEIIITDKKAEIQIGKLPAIKASK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCHHH
VQIRQLFGNLITNAIKYSKEAVAPFIEIYQAENLNVEMPNQNAKFVKIQIKDNGIGMESS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEEEEECCCCCCCHH
HLLKIFTIFQRLHARNEYSGNGIGLAICKKIMENHSGNITVESTLNEGTTFNLYFPIV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]