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The map label for this gene is yybO [H]

Identifier: 146301581

GI number: 146301581

Start: 4554824

End: 4556086

Strand: Direct

Name: yybO [H]

Synonym: Fjoh_3842

Alternate gene names: 146301581

Gene position: 4554824-4556086 (Clockwise)

Preceding gene: 146301580

Following gene: 146301584

Centisome position: 74.71

GC content: 38.24

Gene sequence:

>1263_bases
ATGATTGCTAAATTGAATGAAAAAAAATCCTATCCATGGATTGTTGTTGGCCTGCTGTGGTTTGTTGCTTTATTGAATTA
TTTAGACCGACAAATGCTGTCGACTATGAAATCAGCAATGATGGATGATATTCCCGAATTGGCTAAAGCTGAAAATTTCG
GTCTTTTGATGGCTGTTTTCCTTTGGATTTATGCACTTATGAGTCCTGTTTCCGGAATTATAGCAGATCGGTTTAACCGA
AAAAGAATCATCATTGGAAGTCTTTTTATCTGGTCCGGGGTGACTATGGCGATGGGTTATGCCTCAACTTTCAATCAGAT
TTATATTTTGCGCGGCATTATGGGTTTTAGCGAAGCCTTTTATATTCCGGCTGCCTTATCCTTAATTGCAGATTACCATC
AGGAAAAAACACGCTCTTTTGCCATTGCGATTCATACCACCGGAATTTATTTAGGACAGGCACTTGGTGGTTTTGGTGCC
ACTATTTCTAAGTATTTTTCCTGGCATTTCAGCTTCCACTCAGTAGGTTTATTTGGTGTACTTTACAGTTTAATACTGAT
ATTTTTTATACAAGAAAAGAAAACATACTTCTTAGATCCCACAAAAAAGTCATCTGTCGGCAATGAATTCAGGCAGATGT
TCAAAGGATTAGGAATATTATTCGGTAATATCTCCTTTTGGGTTTTGCTCTTTTATTTCTCTGCACCAAGTTTACCAGGC
TGGGCGGCCAAAAACTGGTTACCCACCTTATTTACTGAAACTTTACATTTAGACATGTCTCTTGCAGGACCAATTGCAAC
GGTAACCATTTCGATGTCTTCCTTTTTTGGCGTTTTAATTGGAGGTGCCATTTCAGACAGATGGGTAATGAAACATCTTA
AAGGAAGAATTTACACCAGCGTTATTGGACTGTTTCTTACCATCCCAGCGTTGTTTTTATTTGGCTATTGCTGTGACATA
GCAGCTATTGTTTTTGGCGCTGTTCTTTTCGGGCTTGGATTTGGAATATACGACACCAATAATATGCCTATTCTTTGTCA
GTTCGTTGCTCCCCGTTACAGGGCTACGGGATATGGAATTATGAATTTTGTTGGTATTTCGGCAGGAGCTGTTATTACAG
AGTTTTTAGGAAAAGCCGCTGATAATGGAGGAATGAGACACGTTTTTGTACTACTCTTATTTGTAGTTTTTAGTGCAATT
GTTTTACAACTGGTGAGCCTGCATCCAAAAACTATTGATATGACTGATGAAATTATCAAATAG

Upstream 100 bases:

>100_bases
CTTGAGAGGGCTTTTATATTTAGTGCCTTTTTATAAAGAAAACAATTCTTTCCTGTTGCGTTTGAATTCGTATATTCGGC
CTTTATTTTGAAAAAAGAGA

Downstream 100 bases:

>100_bases
AGCTTCATACAAAATGGACTTTATCTGATAATCTTCAGTAATTAAAAGCGATCTGAAAGAAAAAAGTAAAGAGAAAAAAG
CAATCCTTTTAACTAACAAT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MIAKLNEKKSYPWIVVGLLWFVALLNYLDRQMLSTMKSAMMDDIPELAKAENFGLLMAVFLWIYALMSPVSGIIADRFNR
KRIIIGSLFIWSGVTMAMGYASTFNQIYILRGIMGFSEAFYIPAALSLIADYHQEKTRSFAIAIHTTGIYLGQALGGFGA
TISKYFSWHFSFHSVGLFGVLYSLILIFFIQEKKTYFLDPTKKSSVGNEFRQMFKGLGILFGNISFWVLLFYFSAPSLPG
WAAKNWLPTLFTETLHLDMSLAGPIATVTISMSSFFGVLIGGAISDRWVMKHLKGRIYTSVIGLFLTIPALFLFGYCCDI
AAIVFGAVLFGLGFGIYDTNNMPILCQFVAPRYRATGYGIMNFVGISAGAVITEFLGKAADNGGMRHVFVLLLFVVFSAI
VLQLVSLHPKTIDMTDEIIK

Sequences:

>Translated_420_residues
MIAKLNEKKSYPWIVVGLLWFVALLNYLDRQMLSTMKSAMMDDIPELAKAENFGLLMAVFLWIYALMSPVSGIIADRFNR
KRIIIGSLFIWSGVTMAMGYASTFNQIYILRGIMGFSEAFYIPAALSLIADYHQEKTRSFAIAIHTTGIYLGQALGGFGA
TISKYFSWHFSFHSVGLFGVLYSLILIFFIQEKKTYFLDPTKKSSVGNEFRQMFKGLGILFGNISFWVLLFYFSAPSLPG
WAAKNWLPTLFTETLHLDMSLAGPIATVTISMSSFFGVLIGGAISDRWVMKHLKGRIYTSVIGLFLTIPALFLFGYCCDI
AAIVFGAVLFGLGFGIYDTNNMPILCQFVAPRYRATGYGIMNFVGISAGAVITEFLGKAADNGGMRHVFVLLLFVVFSAI
VLQLVSLHPKTIDMTDEIIK
>Mature_420_residues
MIAKLNEKKSYPWIVVGLLWFVALLNYLDRQMLSTMKSAMMDDIPELAKAENFGLLMAVFLWIYALMSPVSGIIADRFNR
KRIIIGSLFIWSGVTMAMGYASTFNQIYILRGIMGFSEAFYIPAALSLIADYHQEKTRSFAIAIHTTGIYLGQALGGFGA
TISKYFSWHFSFHSVGLFGVLYSLILIFFIQEKKTYFLDPTKKSSVGNEFRQMFKGLGILFGNISFWVLLFYFSAPSLPG
WAAKNWLPTLFTETLHLDMSLAGPIATVTISMSSFFGVLIGGAISDRWVMKHLKGRIYTSVIGLFLTIPALFLFGYCCDI
AAIVFGAVLFGLGFGIYDTNNMPILCQFVAPRYRATGYGIMNFVGISAGAVITEFLGKAADNGGMRHVFVLLLFVVFSAI
VLQLVSLHPKTIDMTDEIIK

Specific function: Intake Of Galactonate Into The Cell. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=233, Percent_Identity=26.1802575107296, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI215490096, Length=371, Percent_Identity=25.3369272237197, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI14042968, Length=371, Percent_Identity=25.3369272237197, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI215490102, Length=166, Percent_Identity=30.1204819277108, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082320, Length=300, Percent_Identity=24.3333333333333, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI2367379, Length=301, Percent_Identity=23.5880398671096, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789152, Length=453, Percent_Identity=23.3995584988962, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789515, Length=377, Percent_Identity=22.5464190981432, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193209775, Length=397, Percent_Identity=22.6700251889169, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17557872, Length=332, Percent_Identity=24.0963855421687, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17539092, Length=200, Percent_Identity=31, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71992409, Length=431, Percent_Identity=22.737819025522, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920686, Length=376, Percent_Identity=23.936170212766, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24654039, Length=408, Percent_Identity=22.7941176470588, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864456, Length=408, Percent_Identity=22.7941176470588, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654041, Length=326, Percent_Identity=23.3128834355828, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654037, Length=326, Percent_Identity=23.3128834355828, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654044, Length=223, Percent_Identity=24.6636771300448, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46750; Mature: 46750

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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>Mature Secondary Structure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PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]