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The map label for this gene is apbE [H]

Identifier: 146301497

GI number: 146301497

Start: 4453724

End: 4454674

Strand: Direct

Name: apbE [H]

Synonym: Fjoh_3758

Alternate gene names: 146301497

Gene position: 4453724-4454674 (Clockwise)

Preceding gene: 146301496

Following gene: 146301498

Centisome position: 73.05

GC content: 43.85

Gene sequence:

>951_bases
GTGACAGCCGAAAATAACATTCCCAAAACGCAGAAGTATTCCCAGTCGCTAAAACTGATGGGAAACAGTTTTACCATTAC
CGTTGTGGCCGAGAATCAAAAGACCGGTAATGAGTACATCAACCTGGCTGTTGAAGAAATCAGGCGGATCGAAAAACTCC
TGACCACCTACAAAGCGGACAGCCAGACCAATCTGATCAATGAAAATGCAGGAATCAGGCCGGTCAAAATTGATCTGGAA
GTGTTTGATCTTATCGAAAGGTCAATTGGAATTTCAGGAATTACACAGGGCGCTTTTGACATTTCTTATGGAAGCATAGA
CAAAAGTCTCTGGAATTTTGATAAATCCATGAACAGCCTGCCGGATTCCCAGACAGCACTTAGAATGGTCCATCTTATCA
ATTACCGAAATATTATCCTGGACAGGGAAAACACGACGGTATTTTTGAAAGAGAAAGGCATGCGGATCGGTTTTGGGGGT
ATTGGAAAAGGATATGCCGCAGAAAAGGCCAAGCAAGTACTTTTAAAGCATAATGTGCAGAGCGGCATCATCAATGCCAG
CGGAGATCTCTGCGCCTGGGGACTGCAGCCAAACGGGCAAAAATGGACCATCGGCGTGGCGGATCCCGATTCTCCAAACG
CAGCATTCTCTTATATGGAAATCTCTAATAAAGCGGTGGCTACCTCGGGTAATTATGAAAAATACGTAACAATCGACGGT
AAAAAATATTCCCACACCATTGACCCAAAAACGGGACTGCCGATAACCGGAATAAAAAGCGTGACCGTCATTGCATCCAA
CGCTGAATTTGCCGATGCCATGGCCACTCCTATTGCGGTAATGGGCATTCAGGCAGGTCTGTTTTTAATAGATCAGATAC
CGGATCTATATTGTATTATCATTGACGAGAGTAATCAAATTTACACTTCAAAAAACATTCACCTGAGATGA

Upstream 100 bases:

>100_bases
TTAACGCTTCTTTTGGATGCTGAGGGCAGAGTAATCAAAACCTGGCATGGAAAACCCGAAAAAACACCTGAGGAGTGGAC
TGCCGAAATAAAAGCGATCT

Downstream 100 bases:

>100_bases
AAAAACCAAAACAAAAAAGTCTAAAACTTTTATGCAGTACTGCATTTGCCGGTATCCTTATGGGTTCCTGCACCCCGGTA
AAAGAATACCAGAAGGGAAA

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTAENNIPKTQKYSQSLKLMGNSFTITVVAENQKTGNEYINLAVEEIRRIEKLLTTYKADSQTNLINENAGIRPVKIDLE
VFDLIERSIGISGITQGAFDISYGSIDKSLWNFDKSMNSLPDSQTALRMVHLINYRNIILDRENTTVFLKEKGMRIGFGG
IGKGYAAEKAKQVLLKHNVQSGIINASGDLCAWGLQPNGQKWTIGVADPDSPNAAFSYMEISNKAVATSGNYEKYVTIDG
KKYSHTIDPKTGLPITGIKSVTVIASNAEFADAMATPIAVMGIQAGLFLIDQIPDLYCIIIDESNQIYTSKNIHLR

Sequences:

>Translated_316_residues
MTAENNIPKTQKYSQSLKLMGNSFTITVVAENQKTGNEYINLAVEEIRRIEKLLTTYKADSQTNLINENAGIRPVKIDLE
VFDLIERSIGISGITQGAFDISYGSIDKSLWNFDKSMNSLPDSQTALRMVHLINYRNIILDRENTTVFLKEKGMRIGFGG
IGKGYAAEKAKQVLLKHNVQSGIINASGDLCAWGLQPNGQKWTIGVADPDSPNAAFSYMEISNKAVATSGNYEKYVTIDG
KKYSHTIDPKTGLPITGIKSVTVIASNAEFADAMATPIAVMGIQAGLFLIDQIPDLYCIIIDESNQIYTSKNIHLR
>Mature_315_residues
TAENNIPKTQKYSQSLKLMGNSFTITVVAENQKTGNEYINLAVEEIRRIEKLLTTYKADSQTNLINENAGIRPVKIDLEV
FDLIERSIGISGITQGAFDISYGSIDKSLWNFDKSMNSLPDSQTALRMVHLINYRNIILDRENTTVFLKEKGMRIGFGGI
GKGYAAEKAKQVLLKHNVQSGIINASGDLCAWGLQPNGQKWTIGVADPDSPNAAFSYMEISNKAVATSGNYEKYVTIDGK
KYSHTIDPKTGLPITGIKSVTVIASNAEFADAMATPIAVMGIQAGLFLIDQIPDLYCIIIDESNQIYTSKNIHLR

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=271, Percent_Identity=27.3062730627306, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 34779; Mature: 34648

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAENNIPKTQKYSQSLKLMGNSFTITVVAENQKTGNEYINLAVEEIRRIEKLLTTYKAD
CCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
SQTNLINENAGIRPVKIDLEVFDLIERSIGISGITQGAFDISYGSIDKSLWNFDKSMNSL
CCCCEECCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCC
PDSQTALRMVHLINYRNIILDRENTTVFLKEKGMRIGFGGIGKGYAAEKAKQVLLKHNVQ
CCHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHCCC
SGIINASGDLCAWGLQPNGQKWTIGVADPDSPNAAFSYMEISNKAVATSGNYEKYVTIDG
CCEEECCCCEEEECCCCCCCEEEEEECCCCCCCCEEEEEEECCCEEEECCCCEEEEEECC
KKYSHTIDPKTGLPITGIKSVTVIASNAEFADAMATPIAVMGIQAGLFLIDQIPDLYCII
CEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHCCHHEEHHHHCCCEEECCCCEEEEE
IDESNQIYTSKNIHLR
EECCCEEEECCCCEEC
>Mature Secondary Structure 
TAENNIPKTQKYSQSLKLMGNSFTITVVAENQKTGNEYINLAVEEIRRIEKLLTTYKAD
CCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
SQTNLINENAGIRPVKIDLEVFDLIERSIGISGITQGAFDISYGSIDKSLWNFDKSMNSL
CCCCEECCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCC
PDSQTALRMVHLINYRNIILDRENTTVFLKEKGMRIGFGGIGKGYAAEKAKQVLLKHNVQ
CCHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHCCC
SGIINASGDLCAWGLQPNGQKWTIGVADPDSPNAAFSYMEISNKAVATSGNYEKYVTIDG
CCEEECCCCEEEECCCCCCCEEEEEECCCCCCCCEEEEEEECCCEEEECCCCEEEEEECC
KKYSHTIDPKTGLPITGIKSVTVIASNAEFADAMATPIAVMGIQAGLFLIDQIPDLYCII
CEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHCCHHEEHHHHCCCEEECCCCEEEEE
IDESNQIYTSKNIHLR
EECCCEEEECCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]