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The map label for this gene is dinB [H]

Identifier: 146301310

GI number: 146301310

Start: 4259064

End: 4260245

Strand: Direct

Name: dinB [H]

Synonym: Fjoh_3568

Alternate gene names: 146301310

Gene position: 4259064-4260245 (Clockwise)

Preceding gene: 146301308

Following gene: 146301311

Centisome position: 69.86

GC content: 48.22

Gene sequence:

>1182_bases
ATGACAAGGGCAATTGTACACATTGACATGAACACGTTTTTCGTTTCCTGCGAAAGACTAACCAATTCTGAACTTAACGG
GATTCCTCTGATTATCGGCGGAGGAGAAAGGGGCGTGGTGGCTTCGTGTTCCTACGAGGCCAGAAAATTCGGCGTGCGGT
CCGCCATGCCCATTCACATGGCCATGAAATTGTGCCCGCAGGCCAAAATAATGAAAGGCGACATGGAACTTTATTCCAGG
CTCTCCCACGACATTACCGAGATAATCCAGGAAAAAGCGCCCGTGGTAGAAAAGGCAAGTATTGACGAGTTTTATCTCGA
CATCACCGGAATGGACAAATTTTACGGCAGCTACAAATGGACCGATGAGCTGGCGCAGCGCATCACAAAAGAAACAGGCC
TACCCCTCACCTTTGCACTTTCAATAAACAAGACGGTATCCAAAATAGGAACAGGTGAAGGAAAGCAGAAACAGAATCTT
GAAATTCCCGAACATCTGGTGCAGTCTTTTTTAAATCCGCTCTCGATTAGAAAAATCCCTATGGTCGGCCAGAAAACCTT
TGAGCTTCTTTCCCGCATCGGCATCCGCACCATCCAGACACTGTCTGAAATGCCAGCCGAATCACTCCAGCAGATGATCG
GCAAAAACGGCACGGAACTCTGGAAAAAAGCCAATGGAATTGACAACAATCCTGTAGAGCCCTACACGGAAAGAAAATCA
ATTTCAACCGAACATACCTTCTCACAGGACACCATTGATGTATTGAAGCTGAACAGGATCCTTCAGGGCATGGTGGAGAA
ACTGGCCTATCAGCTCCGCGAGGAAGAGTGGCTCACCTCAACGGTGACCGTCAAAATAAGGTACGCCAATTTTGATACCG
AAACCAAGCAGTCCCGTGTGCCTTACACCTCAGCGGATCATATTCTGACCCAGACCGTGACGGATCTCTTTGCCAAACTC
TACCAGCGCCGCATGAGACTGCGCCTTATCGGTGTGCGATTCAGCGGCCTTGTCAGGGGAACCTATCAAATCGACCTGTT
CAATGACACCGAAGAAATGCTCGCGCTCTATCAGGCCATGGACAGGATGAAGACCCGTTACGGATTTGATGCCGTGATGC
GATGCGCCGGCGCATCTTTCAAACCCAATAATAAAGACGAAATTTTAAAACGCAAAAAATAA

Upstream 100 bases:

>100_bases
AAATAAGCATTTCAGAATTTTGTTACTATTTATAACATTATAGATTTTAAAAATGTTATTATCTGTTACTAATTTTGATC
TGTATAAACGGGTAGAAATT

Downstream 100 bases:

>100_bases
ATCATGTACCTCAACTGCCACTCTTTTCATTCCCTGCGCTACGGCACCATTCCGCTGGATGATCTGATCAGGCAGACAGC
CGATTGCGGTGTCACGGCGG

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGERGVVASCSYEARKFGVRSAMPIHMAMKLCPQAKIMKGDMELYSR
LSHDITEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKWTDELAQRITKETGLPLTFALSINKTVSKIGTGEGKQKQNL
EIPEHLVQSFLNPLSIRKIPMVGQKTFELLSRIGIRTIQTLSEMPAESLQQMIGKNGTELWKKANGIDNNPVEPYTERKS
ISTEHTFSQDTIDVLKLNRILQGMVEKLAYQLREEEWLTSTVTVKIRYANFDTETKQSRVPYTSADHILTQTVTDLFAKL
YQRRMRLRLIGVRFSGLVRGTYQIDLFNDTEEMLALYQAMDRMKTRYGFDAVMRCAGASFKPNNKDEILKRKK

Sequences:

>Translated_393_residues
MTRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGERGVVASCSYEARKFGVRSAMPIHMAMKLCPQAKIMKGDMELYSR
LSHDITEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKWTDELAQRITKETGLPLTFALSINKTVSKIGTGEGKQKQNL
EIPEHLVQSFLNPLSIRKIPMVGQKTFELLSRIGIRTIQTLSEMPAESLQQMIGKNGTELWKKANGIDNNPVEPYTERKS
ISTEHTFSQDTIDVLKLNRILQGMVEKLAYQLREEEWLTSTVTVKIRYANFDTETKQSRVPYTSADHILTQTVTDLFAKL
YQRRMRLRLIGVRFSGLVRGTYQIDLFNDTEEMLALYQAMDRMKTRYGFDAVMRCAGASFKPNNKDEILKRKK
>Mature_392_residues
TRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGERGVVASCSYEARKFGVRSAMPIHMAMKLCPQAKIMKGDMELYSRL
SHDITEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKWTDELAQRITKETGLPLTFALSINKTVSKIGTGEGKQKQNLE
IPEHLVQSFLNPLSIRKIPMVGQKTFELLSRIGIRTIQTLSEMPAESLQQMIGKNGTELWKKANGIDNNPVEPYTERKSI
STEHTFSQDTIDVLKLNRILQGMVEKLAYQLREEEWLTSTVTVKIRYANFDTETKQSRVPYTSADHILTQTVTDLFAKLY
QRRMRLRLIGVRFSGLVRGTYQIDLFNDTEEMLALYQAMDRMKTRYGFDAVMRCAGASFKPNNKDEILKRKK

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=379, Percent_Identity=25.8575197889182, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI7706681, Length=233, Percent_Identity=28.3261802575107, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI84043967, Length=233, Percent_Identity=28.3261802575107, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI7705344, Length=109, Percent_Identity=37.6146788990826, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1786425, Length=341, Percent_Identity=32.8445747800587, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1787432, Length=380, Percent_Identity=21.0526315789474, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17537959, Length=391, Percent_Identity=24.2966751918159, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193205700, Length=109, Percent_Identity=33.0275229357798, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534089, Length=188, Percent_Identity=30.3191489361702, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19923006, Length=433, Percent_Identity=23.5565819861432, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI21355641, Length=338, Percent_Identity=22.4852071005917, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644984, Length=338, Percent_Identity=22.4852071005917, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 44869; Mature: 44737

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGERGVVASCSYEARKFGVRSAMPIHM
CCEEEEEEECHHHEEEHHHHCCCCCCCEEEEEECCCCCEEEECCHHHHHHCCCCCCHHHH
AMKLCPQAKIMKGDMELYSRLSHDITEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKW
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCHHHHCCCCC
TDELAQRITKETGLPLTFALSINKTVSKIGTGEGKQKQNLEIPEHLVQSFLNPLSIRKIP
HHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCC
MVGQKTFELLSRIGIRTIQTLSEMPAESLQQMIGKNGTELWKKANGIDNNPVEPYTERKS
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHCC
ISTEHTFSQDTIDVLKLNRILQGMVEKLAYQLREEEWLTSTVTVKIRYANFDTETKQSRV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCHHCCC
PYTSADHILTQTVTDLFAKLYQRRMRLRLIGVRFSGLVRGTYQIDLFNDTEEMLALYQAM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCEEEEEEEEEEECCHHHHHHHHHHH
DRMKTRYGFDAVMRCAGASFKPNNKDEILKRKK
HHHHHHHCHHHHHHHCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
TRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGERGVVASCSYEARKFGVRSAMPIHM
CEEEEEEECHHHEEEHHHHCCCCCCCEEEEEECCCCCEEEECCHHHHHHCCCCCCHHHH
AMKLCPQAKIMKGDMELYSRLSHDITEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKW
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCHHHHCCCCC
TDELAQRITKETGLPLTFALSINKTVSKIGTGEGKQKQNLEIPEHLVQSFLNPLSIRKIP
HHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCC
MVGQKTFELLSRIGIRTIQTLSEMPAESLQQMIGKNGTELWKKANGIDNNPVEPYTERKS
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHCC
ISTEHTFSQDTIDVLKLNRILQGMVEKLAYQLREEEWLTSTVTVKIRYANFDTETKQSRV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCHHCCC
PYTSADHILTQTVTDLFAKLYQRRMRLRLIGVRFSGLVRGTYQIDLFNDTEEMLALYQAM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCEEEEEEEEEEECCHHHHHHHHHHH
DRMKTRYGFDAVMRCAGASFKPNNKDEILKRKK
HHHHHHHCHHHHHHHCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA