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The map label for this gene is yvaG [H]

Identifier: 146300958

GI number: 146300958

Start: 3830550

End: 3831341

Strand: Direct

Name: yvaG [H]

Synonym: Fjoh_3213

Alternate gene names: 146300958

Gene position: 3830550-3831341 (Clockwise)

Preceding gene: 146300957

Following gene: 146300962

Centisome position: 62.83

GC content: 35.23

Gene sequence:

>792_bases
ATGAATTTAAAATTAGAAGGAAAAAAAGCTTTCATCAGCGGTTCGACACAAGGAATTGGTTTTGCGATTGCAAAACAATT
ATTAAATGAAAAAGCCGAAGTTATTATTAACGGAAGAAATGAAGAAAAAACCAACCTGGCGGTTCAAAAATTAAAAGATG
AATTTCCAAATGCCGCAGTTTCAGGTATTGTGTGTGATTTTGGAAATAAAGCAGAAGTAACCGCATTATTAAACCAGCTA
AACGATATTGACATTTTAATAAACAACGTAGGTATTTTTGAATTAAAAGATTTTGAAACGATAGAAGACGAAGACTGGTA
CCGAATTTTTGAGATTAATGTAATGAGCAGTGTCAAACTTTCTAAGAAACTTTTACCGCAGATGCTTCAGAAAAAATCTG
GAAGAATTATTTTCATCAGCAGTGAATCTGGTGTGAATATTCCCGGAAACATGATTCATTACGGAATGACAAAAGCAGCT
ATGATGGCTGTTGGCAATGGTTTATCAAAACTAACTTTAGGAACCGAAGTTACTGTCAATACTATTTTAGGCGGTCCAAC
TTATTCTGATGGTGTTGCCTCAACAATCGAACATATTGCTTCTTTACAAAATATAGAAATCGAGCAAATGAAAAGTGCTA
TTATACAGCAGACGAATCCGCATTCTTTATTACAGCGTTTTATCGATCCGGCAGAAATTGCTTCTTTGGCTGTTTATTTA
TCAAGCCCGCTTGCCATTGCAACAAACGGTTCATGTCTTAGAGCCGATGGAGGCGTTTTAAAAACGGTGTAA

Upstream 100 bases:

>100_bases
AAACGTCCTAAAAAAACAAATCGAAATGCAATTAGCTGTTATCAGCTAATTTTTTTGACTATTTATGTATCGATCATTAC
AAAAATTAAAATAATAAAAA

Downstream 100 bases:

>100_bases
CTTAAATCTAAAAATCCTGTTTAGTTAACCTAAACAGGATTAAAAGCCAACCCATTATATAATATTTTATTTAAAACAGT
ATTCTAATCAGCACCGCCGT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNLKLEGKKAFISGSTQGIGFAIAKQLLNEKAEVIINGRNEEKTNLAVQKLKDEFPNAAVSGIVCDFGNKAEVTALLNQL
NDIDILINNVGIFELKDFETIEDEDWYRIFEINVMSSVKLSKKLLPQMLQKKSGRIIFISSESGVNIPGNMIHYGMTKAA
MMAVGNGLSKLTLGTEVTVNTILGGPTYSDGVASTIEHIASLQNIEIEQMKSAIIQQTNPHSLLQRFIDPAEIASLAVYL
SSPLAIATNGSCLRADGGVLKTV

Sequences:

>Translated_263_residues
MNLKLEGKKAFISGSTQGIGFAIAKQLLNEKAEVIINGRNEEKTNLAVQKLKDEFPNAAVSGIVCDFGNKAEVTALLNQL
NDIDILINNVGIFELKDFETIEDEDWYRIFEINVMSSVKLSKKLLPQMLQKKSGRIIFISSESGVNIPGNMIHYGMTKAA
MMAVGNGLSKLTLGTEVTVNTILGGPTYSDGVASTIEHIASLQNIEIEQMKSAIIQQTNPHSLLQRFIDPAEIASLAVYL
SSPLAIATNGSCLRADGGVLKTV
>Mature_263_residues
MNLKLEGKKAFISGSTQGIGFAIAKQLLNEKAEVIINGRNEEKTNLAVQKLKDEFPNAAVSGIVCDFGNKAEVTALLNQL
NDIDILINNVGIFELKDFETIEDEDWYRIFEINVMSSVKLSKKLLPQMLQKKSGRIIFISSESGVNIPGNMIHYGMTKAA
MMAVGNGLSKLTLGTEVTVNTILGGPTYSDGVASTIEHIASLQNIEIEQMKSAIIQQTNPHSLLQRFIDPAEIASLAVYL
SSPLAIATNGSCLRADGGVLKTV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=28.968253968254, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=31.25, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI126723191, Length=170, Percent_Identity=28.2352941176471, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=26.7175572519084, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=26.0536398467433, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI226371731, Length=164, Percent_Identity=28.6585365853659, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI4504505, Length=189, Percent_Identity=26.984126984127, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI10190704, Length=275, Percent_Identity=27.6363636363636, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI210032110, Length=170, Percent_Identity=27.0588235294118, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=28.515625, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=30.0380228136882, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790717, Length=267, Percent_Identity=27.3408239700375, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787335, Length=261, Percent_Identity=27.5862068965517, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787905, Length=262, Percent_Identity=31.2977099236641, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=24.5136186770428, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=25, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787820, Length=193, Percent_Identity=30.5699481865285, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87082160, Length=266, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789208, Length=268, Percent_Identity=24.2537313432836, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=28.0155642023346, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=27.6923076923077, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=186, Percent_Identity=30.6451612903226, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=205, Percent_Identity=28.780487804878, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=196, Percent_Identity=31.6326530612245, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=168, Percent_Identity=32.1428571428571, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=28.2352941176471, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=169, Percent_Identity=31.3609467455621, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=27.34375, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=173, Percent_Identity=31.2138728323699, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=182, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=164, Percent_Identity=29.8780487804878, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=190, Percent_Identity=29.4736842105263, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=167, Percent_Identity=29.3413173652695, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI21355319, Length=193, Percent_Identity=29.0155440414508, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24584748, Length=166, Percent_Identity=30.1204819277108, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161076933, Length=166, Percent_Identity=30.1204819277108, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=27.1317829457364, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21358495, Length=188, Percent_Identity=28.1914893617021, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=26.1538461538462, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=27.1317829457364, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281364892, Length=171, Percent_Identity=30.4093567251462, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24643142, Length=224, Percent_Identity=27.2321428571429, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18859837, Length=273, Percent_Identity=22.7106227106227, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28455; Mature: 28455

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKLEGKKAFISGSTQGIGFAIAKQLLNEKAEVIINGRNEEKTNLAVQKLKDEFPNAAV
CCCEECCCEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHH
SGIVCDFGNKAEVTALLNQLNDIDILINNVGIFELKDFETIEDEDWYRIFEINVMSSVKL
HEEEECCCCCHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCCCCCEEEEEEEEHHHHHH
SKKLLPQMLQKKSGRIIFISSESGVNIPGNMIHYGMTKAAMMAVGNGLSKLTLGTEVTVN
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHEECCCEEEEE
TILGGPTYSDGVASTIEHIASLQNIEIEQMKSAIIQQTNPHSLLQRFIDPAEIASLAVYL
EEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHH
SSPLAIATNGSCLRADGGVLKTV
CCCEEEEECCCEEECCCCEEECC
>Mature Secondary Structure
MNLKLEGKKAFISGSTQGIGFAIAKQLLNEKAEVIINGRNEEKTNLAVQKLKDEFPNAAV
CCCEECCCEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHH
SGIVCDFGNKAEVTALLNQLNDIDILINNVGIFELKDFETIEDEDWYRIFEINVMSSVKL
HEEEECCCCCHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCCCCCEEEEEEEEHHHHHH
SKKLLPQMLQKKSGRIIFISSESGVNIPGNMIHYGMTKAAMMAVGNGLSKLTLGTEVTVN
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHEECCCEEEEE
TILGGPTYSDGVASTIEHIASLQNIEIEQMKSAIIQQTNPHSLLQRFIDPAEIASLAVYL
EEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHH
SSPLAIATNGSCLRADGGVLKTV
CCCEEEEECCCEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]