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The map label for this gene is rsbS [H]

Identifier: 146300881

GI number: 146300881

Start: 3725973

End: 3726371

Strand: Reverse

Name: rsbS [H]

Synonym: Fjoh_3136

Alternate gene names: 146300881

Gene position: 3726371-3725973 (Counterclockwise)

Preceding gene: 146300882

Following gene: 146300880

Centisome position: 61.12

GC content: 38.35

Gene sequence:

>399_bases
ATGGAAAGAATTCCAATACTCAAGATGGGAGATTTTCTGCTGGTTACCATACAGGTTGATTTGTATGACCAATTGGCTGA
AAATCTTGAATCTGATTTAATAAATACTATAAACAAGAACAATTCAAAGGGCGTTTTGATTGATATATCAGCAGTTTCCA
TTATCGATTCCTTTATGGGAAGGATTTTGGGAAATATCGCCGTTATGTCAAAAATTATGGATGCACAGACAGTAGTGGTG
GGCATGCAGCCTGCGGTTGCTATTACACTGGTTGAACTTGGATTATCTTTAAACGGTGTTATTAGTGCTTTAAATGTTGA
GAAAGGCATGGATTTGCTTCGCGCGAAAATGTACAATGGCGATAACGAGGAGCAGACGTATGACGACAGCAACGAATAA

Upstream 100 bases:

>100_bases
AATTATTACAAAAGCTTCGCTTGCAAGCGCTCTTCAAACAGCCTTTGAAATGTTACAGCTTACGGTTGTGAAAAGAAAAT
AACGAATTAAGATTACTGAC

Downstream 100 bases:

>100_bases
AGAAGAACTGCTTATTGTAAAAGAGCAGGATGTAGTTCCATTACGCAACCGCGTAAAGGAGTATGGCGTAAAAATTGGAA
TGAGTATTTTAAACCAGACC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MERIPILKMGDFLLVTIQVDLYDQLAENLESDLINTINKNNSKGVLIDISAVSIIDSFMGRILGNIAVMSKIMDAQTVVV
GMQPAVAITLVELGLSLNGVISALNVEKGMDLLRAKMYNGDNEEQTYDDSNE

Sequences:

>Translated_132_residues
MERIPILKMGDFLLVTIQVDLYDQLAENLESDLINTINKNNSKGVLIDISAVSIIDSFMGRILGNIAVMSKIMDAQTVVV
GMQPAVAITLVELGLSLNGVISALNVEKGMDLLRAKMYNGDNEEQTYDDSNE
>Mature_132_residues
MERIPILKMGDFLLVTIQVDLYDQLAENLESDLINTINKNNSKGVLIDISAVSIIDSFMGRILGNIAVMSKIMDAQTVVV
GMQPAVAITLVELGLSLNGVISALNVEKGMDLLRAKMYNGDNEEQTYDDSNE

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 14434; Mature: 14434

Theoretical pI: Translated: 3.97; Mature: 3.97

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIPILKMGDFLLVTIQVDLYDQLAENLESDLINTINKNNSKGVLIDISAVSIIDSFMG
CCCCCEEEECCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHH
RILGNIAVMSKIMDAQTVVVGMQPAVAITLVELGLSLNGVISALNVEKGMDLLRAKMYNG
HHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
DNEEQTYDDSNE
CCCCCCCCCCCC
>Mature Secondary Structure
MERIPILKMGDFLLVTIQVDLYDQLAENLESDLINTINKNNSKGVLIDISAVSIIDSFMG
CCCCCEEEECCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHH
RILGNIAVMSKIMDAQTVVVGMQPAVAITLVELGLSLNGVISALNVEKGMDLLRAKMYNG
HHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
DNEEQTYDDSNE
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]