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The map label for this gene is yfcX [C]

Identifier: 146300845

GI number: 146300845

Start: 3669140

End: 3669943

Strand: Direct

Name: yfcX [C]

Synonym: Fjoh_3100

Alternate gene names: 146300845

Gene position: 3669140-3669943 (Clockwise)

Preceding gene: 146300843

Following gene: 146300846

Centisome position: 60.18

GC content: 40.3

Gene sequence:

>804_bases
ATGATTTTTACCACACACAAAATTACAAATGGATACTGGAAAATCAGTTTCAACAATCCTCCTATTAACATGTTTGATAC
CGAATTTTCTAAACAGTTAATGACTATAATGGACGAACTGGAGTCAAATGAAAACCTAAAAGTTGTAGTCTTTGAGAGTG
AAAATCCAGACTTTTTTGTTGCTCATGTAGAATTGCTAAATGTTGGAGACTTTCCAAAAGGAACCGGAAAAACAGGCCTT
TCTATAGCTTGGCCAGATATTGCGCGCAGACTGGAACTTGCCCCTTTTGTAACCATAGCTTCCATCCGTGGCCGTGCCAG
AGGACTTGGAAGTGAATTTGCACAAGCATTTGATTTACGCTTTGCCAGCAGAGAGAAAGCATTCTTGGCTCAGGTAGAAA
TAGGAATAGGTTCATTTCCTGGTGGCGGAGGACTTGAGCGTCTGCATCTCCTTACAGGACGCAGCCGAGCTCTTGAAATT
ATTTTAAGCGGTAACGATTATGATGCAGATACGGCCGCTTTCTATGGCTGGATAAACCGTTCAATTCCAGACGCTGAACT
GGATGAATATGTTGAAAAATTTGCAAAGCGCATAGATTCATTTGACAAAAAACCAATTGCTGCCATAAAGCAGATTATGA
ACCAAAGAGCCAAACTTCCTTCAAACGAAGAAATTTTAGACACACAGGTTAAATTCTTTGCTTCACTTGAGGAGCCGGAA
GCGCGCAATCGTATTAAGAATCTATTTGAAAGAGGACTCCAGCAAAATGGCGATCTGGAACTAAATCTTGCTAATAACAT
CTAA

Upstream 100 bases:

>100_bases
TTATTATTTCAACTACTTGCATTTTGCAAGTAAATTTAATTATATTTGTACTTTCAATTTGCAAGTAAAATTACAAAAAA
TTAACCAAAACGACTACATT

Downstream 100 bases:

>100_bases
AAATATGAAAGCATACATCTTCCCTAAATATGGCAAAACAGAAAAATTATTACTCAGCGATGTAAAAATACCTGAAATTG
GAGATTATGAGGTATTAGTA

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MIFTTHKITNGYWKISFNNPPINMFDTEFSKQLMTIMDELESNENLKVVVFESENPDFFVAHVELLNVGDFPKGTGKTGL
SIAWPDIARRLELAPFVTIASIRGRARGLGSEFAQAFDLRFASREKAFLAQVEIGIGSFPGGGGLERLHLLTGRSRALEI
ILSGNDYDADTAAFYGWINRSIPDAELDEYVEKFAKRIDSFDKKPIAAIKQIMNQRAKLPSNEEILDTQVKFFASLEEPE
ARNRIKNLFERGLQQNGDLELNLANNI

Sequences:

>Translated_267_residues
MIFTTHKITNGYWKISFNNPPINMFDTEFSKQLMTIMDELESNENLKVVVFESENPDFFVAHVELLNVGDFPKGTGKTGL
SIAWPDIARRLELAPFVTIASIRGRARGLGSEFAQAFDLRFASREKAFLAQVEIGIGSFPGGGGLERLHLLTGRSRALEI
ILSGNDYDADTAAFYGWINRSIPDAELDEYVEKFAKRIDSFDKKPIAAIKQIMNQRAKLPSNEEILDTQVKFFASLEEPE
ARNRIKNLFERGLQQNGDLELNLANNI
>Mature_267_residues
MIFTTHKITNGYWKISFNNPPINMFDTEFSKQLMTIMDELESNENLKVVVFESENPDFFVAHVELLNVGDFPKGTGKTGL
SIAWPDIARRLELAPFVTIASIRGRARGLGSEFAQAFDLRFASREKAFLAQVEIGIGSFPGGGGLERLHLLTGRSRALEI
ILSGNDYDADTAAFYGWINRSIPDAELDEYVEKFAKRIDSFDKKPIAAIKQIMNQRAKLPSNEEILDTQVKFFASLEEPE
ARNRIKNLFERGLQQNGDLELNLANNI

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI20127408, Length=192, Percent_Identity=26.0416666666667, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI194097323, Length=117, Percent_Identity=37.6068376068376, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1788682, Length=177, Percent_Identity=31.638418079096, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788597, Length=241, Percent_Identity=22.8215767634855, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790281, Length=186, Percent_Identity=30.6451612903226, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787659, Length=202, Percent_Identity=27.7227722772277, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25144276, Length=206, Percent_Identity=29.126213592233, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508951, Length=206, Percent_Identity=29.126213592233, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=206, Percent_Identity=29.126213592233, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=186, Percent_Identity=26.8817204301075, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=196, Percent_Identity=26.530612244898, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20129971, Length=201, Percent_Identity=26.3681592039801, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24653477, Length=201, Percent_Identity=26.3681592039801, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 30066; Mature: 30066

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFTTHKITNGYWKISFNNPPINMFDTEFSKQLMTIMDELESNENLKVVVFESENPDFFV
CEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEE
AHVELLNVGDFPKGTGKTGLSIAWPDIARRLELAPFVTIASIRGRARGLGSEFAQAFDLR
EEEEEEECCCCCCCCCCCCCEEECHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHH
FASREKAFLAQVEIGIGSFPGGGGLERLHLLTGRSRALEIILSGNDYDADTAAFYGWINR
HHCCCHHEEEEEEECCCCCCCCCCHHHHHEECCCCEEEEEEECCCCCCCHHHHHHHHHCC
SIPDAELDEYVEKFAKRIDSFDKKPIAAIKQIMNQRAKLPSNEEILDTQVKFFASLEEPE
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCH
ARNRIKNLFERGLQQNGDLELNLANNI
HHHHHHHHHHHHHCCCCCEEEEECCCC
>Mature Secondary Structure
MIFTTHKITNGYWKISFNNPPINMFDTEFSKQLMTIMDELESNENLKVVVFESENPDFFV
CEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEE
AHVELLNVGDFPKGTGKTGLSIAWPDIARRLELAPFVTIASIRGRARGLGSEFAQAFDLR
EEEEEEECCCCCCCCCCCCCEEECHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHH
FASREKAFLAQVEIGIGSFPGGGGLERLHLLTGRSRALEIILSGNDYDADTAAFYGWINR
HHCCCHHEEEEEEECCCCCCCCCCHHHHHEECCCCEEEEEEECCCCCCCHHHHHHHHHCC
SIPDAELDEYVEKFAKRIDSFDKKPIAAIKQIMNQRAKLPSNEEILDTQVKFFASLEEPE
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCH
ARNRIKNLFERGLQQNGDLELNLANNI
HHHHHHHHHHHHHCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA