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The map label for this gene is sglT [H]

Identifier: 146300711

GI number: 146300711

Start: 3512460

End: 3514184

Strand: Direct

Name: sglT [H]

Synonym: Fjoh_2962

Alternate gene names: 146300711

Gene position: 3512460-3514184 (Clockwise)

Preceding gene: 146300710

Following gene: 146300712

Centisome position: 57.61

GC content: 35.36

Gene sequence:

>1725_bases
ATGCAGCTATTTGACTGGATCGTACTTATTGTAACCCTTTTATTCATTGTTGGATATGGTTCATGGAAAACCAAAGGAAG
CAAAAACGTTGAAGACTTTATTTTAGGAAACAACGAAACTCCGTGGTACACCGTTGGACTTTCTGTAATGGCAACACAGG
CCAGCGCCATTACTTTTTTGTCTACACCGGGACAGGCTTATCACGACGGAATGGGATTTGTTCAATTCTATTTCGGACTT
CCAATTGCCATGATTGTGATTTGTTTGACATTTATTCCGCTTTATCACAAATACAAAGTATTTACTGCCTATGAATTTCT
CGAAAAACGATTTGATGTAAAAACACGTTCGCTTGCCGCTATCCTGTTTTTAGTACAACGAGGATTAGGAACCGGACTTA
CCATTTATGCCCCTGCCATTATTTTGTCGGCACTTTTGGGCTGGAACCTTACCGTTATGAATATCATAATTGGGGTAATG
GTAATTATTTATACGTTTTCTGGAGGAACCAAAGCCGTAAACGTTACGCAGAAACAGCAGATGTTTGTAATCATGTCGGG
AATGTTTATCACCTTTTTCCTGATTCTGCATTATCTGCCAAACGATATGACTTTTACAAGTGCTTTGCATATTGCTGGTG
CAAACGATAAAATGAATATTGTGGATTTCTCTTTTGATCCAGAAGAAAAATATACTTTTTGGAGCGGTATTACCGGAGGA
TTTTTCTTAGCCCTCGCCTATTTTGGTACAGATCAGTCGCAGGTTGGAAGATATTTATCAGGAAAATCAGTTGCTGAAAG
CCAGATGGGATTAATCATGAACGGACTTTTAAAAGTTCCAATGCAGTTTTTCATACTTCTTACCGGAGTAATGGTATTTG
TGTTTTTTCAGTTCAATCCAGTTCCGTTAAATTTTAATCCGAACAATAAAGTTGTAATCGAAAAATCAGCTTATAAAGAA
GAATACCATGCTTTAGAAAAAAAACTAAGCAAACTTTCTGAAGATAAAAAAGTAATTAATCTGCTGTATATCGATCAGTT
AAATCAGGATTACGATAATCCGATTCTGAGAAAAGAATTAGTGAATTTGTCGAATAAAGAAAAAGATTTACGCGACCGCG
CCAAAGAAATCATTTCAAGAGCCGACAGCAACAGCGAAACGAATGATAAAGATTATGTCTTTTTCCATTTCATTCTGCAT
TATTTACCAAAAGGATTAATTGGTTTACTGCTTGCCGTGATTCTTTCAGCTGCCATGTCATCAACAGCTTCCGGATTAAA
CGCTTTGGCTTCTACAACCGCAATCGACATTTACAAAAGAAACCTCAAAACCGAAAAATCAGAGAAACATTATCTTCATG
CAACTAAATTTTTTACTTTATTTTGGGGAGTTGTAGCAATACTTTTTGCTTGTGTGGGAACTTTGTTTGAGAATTTAATT
CAGCTTGTAAACATCATTGGATCTATCTTTTACGGAACAGTTCTGGGAATCTTCCTTGTTGGTTTTTATTTAAAAAGAGT
TCAGGCAAAACCAATGTTTATCAGCGCTATTATTAGTCAGTTAACCATTTTTGTAATTTATTATTACATGATTTACAGTC
AGGAAAAATTAGGCTATTTATGGCTGAATTTCATTGGTGCGATTTTAACTATTGTATTGTCGCTTTTATTGCAATTCTTA
TTTTTTAAAGGAAAACCAAATGATGAAGAGCTGGTATTAGAATAA

Upstream 100 bases:

>100_bases
AAAACAAAAAAATGGAAAAAAAGCTACACCTATGTTTTGGTAGCTAACGCAATTTACATTGTGATTTTTTTCTTAATCAT
GCAATTTTATTCATAACCTT

Downstream 100 bases:

>100_bases
TACATCTCTTGTTATTACACATAATTTTGTCATTTCGACAAAGAAGAAATCACATTAGAAAATCTACAAAGATTGTCGGC
TTTCTACGCAGAAACACTGG

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MQLFDWIVLIVTLLFIVGYGSWKTKGSKNVEDFILGNNETPWYTVGLSVMATQASAITFLSTPGQAYHDGMGFVQFYFGL
PIAMIVICLTFIPLYHKYKVFTAYEFLEKRFDVKTRSLAAILFLVQRGLGTGLTIYAPAIILSALLGWNLTVMNIIIGVM
VIIYTFSGGTKAVNVTQKQQMFVIMSGMFITFFLILHYLPNDMTFTSALHIAGANDKMNIVDFSFDPEEKYTFWSGITGG
FFLALAYFGTDQSQVGRYLSGKSVAESQMGLIMNGLLKVPMQFFILLTGVMVFVFFQFNPVPLNFNPNNKVVIEKSAYKE
EYHALEKKLSKLSEDKKVINLLYIDQLNQDYDNPILRKELVNLSNKEKDLRDRAKEIISRADSNSETNDKDYVFFHFILH
YLPKGLIGLLLAVILSAAMSSTASGLNALASTTAIDIYKRNLKTEKSEKHYLHATKFFTLFWGVVAILFACVGTLFENLI
QLVNIIGSIFYGTVLGIFLVGFYLKRVQAKPMFISAIISQLTIFVIYYYMIYSQEKLGYLWLNFIGAILTIVLSLLLQFL
FFKGKPNDEELVLE

Sequences:

>Translated_574_residues
MQLFDWIVLIVTLLFIVGYGSWKTKGSKNVEDFILGNNETPWYTVGLSVMATQASAITFLSTPGQAYHDGMGFVQFYFGL
PIAMIVICLTFIPLYHKYKVFTAYEFLEKRFDVKTRSLAAILFLVQRGLGTGLTIYAPAIILSALLGWNLTVMNIIIGVM
VIIYTFSGGTKAVNVTQKQQMFVIMSGMFITFFLILHYLPNDMTFTSALHIAGANDKMNIVDFSFDPEEKYTFWSGITGG
FFLALAYFGTDQSQVGRYLSGKSVAESQMGLIMNGLLKVPMQFFILLTGVMVFVFFQFNPVPLNFNPNNKVVIEKSAYKE
EYHALEKKLSKLSEDKKVINLLYIDQLNQDYDNPILRKELVNLSNKEKDLRDRAKEIISRADSNSETNDKDYVFFHFILH
YLPKGLIGLLLAVILSAAMSSTASGLNALASTTAIDIYKRNLKTEKSEKHYLHATKFFTLFWGVVAILFACVGTLFENLI
QLVNIIGSIFYGTVLGIFLVGFYLKRVQAKPMFISAIISQLTIFVIYYYMIYSQEKLGYLWLNFIGAILTIVLSLLLQFL
FFKGKPNDEELVLE
>Mature_574_residues
MQLFDWIVLIVTLLFIVGYGSWKTKGSKNVEDFILGNNETPWYTVGLSVMATQASAITFLSTPGQAYHDGMGFVQFYFGL
PIAMIVICLTFIPLYHKYKVFTAYEFLEKRFDVKTRSLAAILFLVQRGLGTGLTIYAPAIILSALLGWNLTVMNIIIGVM
VIIYTFSGGTKAVNVTQKQQMFVIMSGMFITFFLILHYLPNDMTFTSALHIAGANDKMNIVDFSFDPEEKYTFWSGITGG
FFLALAYFGTDQSQVGRYLSGKSVAESQMGLIMNGLLKVPMQFFILLTGVMVFVFFQFNPVPLNFNPNNKVVIEKSAYKE
EYHALEKKLSKLSEDKKVINLLYIDQLNQDYDNPILRKELVNLSNKEKDLRDRAKEIISRADSNSETNDKDYVFFHFILH
YLPKGLIGLLLAVILSAAMSSTASGLNALASTTAIDIYKRNLKTEKSEKHYLHATKFFTLFWGVVAILFACVGTLFENLI
QLVNIIGSIFYGTVLGIFLVGFYLKRVQAKPMFISAIISQLTIFVIYYYMIYSQEKLGYLWLNFIGAILTIVLSLLLQFL
FFKGKPNDEELVLE

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI4507035, Length=298, Percent_Identity=29.8657718120805, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI167466278, Length=256, Percent_Identity=32.03125, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI157671931, Length=274, Percent_Identity=28.8321167883212, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI256985183, Length=293, Percent_Identity=25.938566552901, Blast_Score=106, Evalue=8e-23,
Organism=Homo sapiens, GI109659839, Length=536, Percent_Identity=21.6417910447761, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4507033, Length=318, Percent_Identity=23.5849056603774, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI206597483, Length=299, Percent_Identity=25.0836120401338, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI14140236, Length=312, Percent_Identity=23.7179487179487, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI110835708, Length=327, Percent_Identity=25.0764525993884, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI17941285, Length=316, Percent_Identity=25, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI109659836, Length=363, Percent_Identity=23.1404958677686, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI206597487, Length=226, Percent_Identity=27.8761061946903, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4507031, Length=316, Percent_Identity=24.0506329113924, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1790113, Length=294, Percent_Identity=25.1700680272109, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115533094, Length=305, Percent_Identity=27.2131147540984, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32566512, Length=193, Percent_Identity=27.979274611399, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573698, Length=299, Percent_Identity=26.7558528428094, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28574994, Length=298, Percent_Identity=29.1946308724832, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24641117, Length=275, Percent_Identity=29.8181818181818, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281362918, Length=301, Percent_Identity=27.2425249169435, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24651739, Length=303, Percent_Identity=25.0825082508251, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24651741, Length=273, Percent_Identity=24.9084249084249, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI161076631, Length=262, Percent_Identity=26.3358778625954, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24645928, Length=274, Percent_Identity=24.8175182481752, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281364280, Length=235, Percent_Identity=25.1063829787234, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640370, Length=252, Percent_Identity=26.5873015873016, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920916, Length=250, Percent_Identity=26.8, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI221459584, Length=280, Percent_Identity=24.2857142857143, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221459582, Length=238, Percent_Identity=25.2100840336134, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281362054, Length=269, Percent_Identity=22.6765799256506, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362052, Length=269, Percent_Identity=22.6765799256506, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362050, Length=269, Percent_Identity=22.6765799256506, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648056, Length=269, Percent_Identity=22.6765799256506, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356827, Length=269, Percent_Identity=22.6765799256506, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221379702, Length=245, Percent_Identity=24.8979591836735, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221459588, Length=244, Percent_Identity=25.4098360655738, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24650192, Length=252, Percent_Identity=24.2063492063492, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221459586, Length=238, Percent_Identity=25.6302521008403, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 64981; Mature: 64981

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLFDWIVLIVTLLFIVGYGSWKTKGSKNVEDFILGNNETPWYTVGLSVMATQASAITFL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEECCCCCCEEEECHHHHHHHHHHEEEE
STPGQAYHDGMGFVQFYFGLPIAMIVICLTFIPLYHKYKVFTAYEFLEKRFDVKTRSLAA
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILFLVQRGLGTGLTIYAPAIILSALLGWNLTVMNIIIGVMVIIYTFSGGTKAVNVTQKQQ
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECHHHH
MFVIMSGMFITFFLILHYLPNDMTFTSALHIAGANDKMNIVDFSFDPEEKYTFWSGITGG
HHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEECCCCCCEEEEECCCCCCCEEECCCCHHH
FFLALAYFGTDQSQVGRYLSGKSVAESQMGLIMNGLLKVPMQFFILLTGVMVFVFFQFNP
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPLNFNPNNKVVIEKSAYKEEYHALEKKLSKLSEDKKVINLLYIDQLNQDYDNPILRKEL
EEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VNLSNKEKDLRDRAKEIISRADSNSETNDKDYVFFHFILHYLPKGLIGLLLAVILSAAMS
HCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STASGLNALASTTAIDIYKRNLKTEKSEKHYLHATKFFTLFWGVVAILFACVGTLFENLI
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVNIIGSIFYGTVLGIFLVGFYLKRVQAKPMFISAIISQLTIFVIYYYMIYSQEKLGYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
WLNFIGAILTIVLSLLLQFLFFKGKPNDEELVLE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQLFDWIVLIVTLLFIVGYGSWKTKGSKNVEDFILGNNETPWYTVGLSVMATQASAITFL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEECCCCCCEEEECHHHHHHHHHHEEEE
STPGQAYHDGMGFVQFYFGLPIAMIVICLTFIPLYHKYKVFTAYEFLEKRFDVKTRSLAA
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILFLVQRGLGTGLTIYAPAIILSALLGWNLTVMNIIIGVMVIIYTFSGGTKAVNVTQKQQ
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECHHHH
MFVIMSGMFITFFLILHYLPNDMTFTSALHIAGANDKMNIVDFSFDPEEKYTFWSGITGG
HHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEECCCCCCEEEEECCCCCCCEEECCCCHHH
FFLALAYFGTDQSQVGRYLSGKSVAESQMGLIMNGLLKVPMQFFILLTGVMVFVFFQFNP
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPLNFNPNNKVVIEKSAYKEEYHALEKKLSKLSEDKKVINLLYIDQLNQDYDNPILRKEL
EEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VNLSNKEKDLRDRAKEIISRADSNSETNDKDYVFFHFILHYLPKGLIGLLLAVILSAAMS
HCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STASGLNALASTTAIDIYKRNLKTEKSEKHYLHATKFFTLFWGVVAILFACVGTLFENLI
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVNIIGSIFYGTVLGIFLVGFYLKRVQAKPMFISAIISQLTIFVIYYYMIYSQEKLGYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
WLNFIGAILTIVLSLLLQFLFFKGKPNDEELVLE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]