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The map label for this gene is ccpA [H]

Identifier: 146300460

GI number: 146300460

Start: 3224740

End: 3225750

Strand: Direct

Name: ccpA [H]

Synonym: Fjoh_2710

Alternate gene names: 146300460

Gene position: 3224740-3225750 (Clockwise)

Preceding gene: 146300459

Following gene: 146300461

Centisome position: 52.89

GC content: 32.54

Gene sequence:

>1011_bases
ATGAAAAAGATTACAATTAGAGATATTGCTAAACAAGCAGAAGTTTCTATTTCTACCGTATCTTTTGTTATCAATGGTAA
AGGAGAAAAAATGGCTATTAGTCCTGCTGTTATTAAAAAAGTTCAGGATGTTGCGCAAAAACTTCAATACAAGCCAAGTA
TGATTGCAAGCAGTTTACGGACTGGAAAAACAAGATCAATTGGGCTTATTGTAGAAGATATTTCAAATCAGTTTTTTGCT
GATTTGGCAAGAGTAATCGAAGATGAAGCCAAAAATATTAACTACAGGGTTTTTTATTGCAGTACAGGAGATGATAATGA
TCGTTCTGAAGAATTAGTGCAGAGTCTTTTGCAGGCAAATGTTGAAGGTTTTATTATTACCCCAACCCGAAATTTAGAAA
AAACAATAAGCCAGCTTTTAAAATTGCAAAAACCGGTTGTGTTAATCGACAGGTATTTTGCAAACCAAAAAGTAAGTCAT
GTTGTAATGGATAATTATGAAGGATCTTATTCGGCTGTTAAATTTTTAATCAGCAAAGGACGCAAAAACATAGCTGTCGT
AAATAATAAGTCTGGAATGATTCAGATGAAGTTACGTGAAAAAGGATATGTAGAAGCGCTTAAGGAGGAAGGAATTTATA
ATGAAAAATATACGCTGCTTTTAGATTATCATTCGAGTGAGAAAACCAGAATTGAAGAAATTATCAATTTCTTTAATCAA
AACAAAGAAATAGATGCAGTTCTGTTTTGTGCAAACTATATGGGACTTGCGGGACTTCAGGCTTTTAGAACTTTAAATTA
TAAAATTCCCAATGATATTTCGGTTATCAGCTTTGATGACCATGACAGTTTTAAATTGCATACACCGACAATTTCGGTTA
TTGCCCAGCCAATAGAAGACATTGCTGTAGAATCAATCCAGTTATTGATGAGCCAGATGACAAATTTTGAAGATTTTAAA
ATAGAAAAAGTTCTCAAAAAAGGAACTTTGATAATAAGAGAATCCGTTTAA

Upstream 100 bases:

>100_bases
AACGATTTATTGAAAATAAATTTTACTAAAACGTTTTTGTAAGTTTCGTTTGCATATATTTGCGATGTACTAAAATATCC
AATAATAAATTATTTACCAG

Downstream 100 bases:

>100_bases
CCAACCGAATAGCAGATTTAAAATTAGAAATGAAAAAAGTGGAGACTTTTTTTTAATCATTTCACTAAAACGATTTAGTA
AATATTTTCCTTGATTTACT

Product: regulatory protein LacI

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKKITIRDIAKQAEVSISTVSFVINGKGEKMAISPAVIKKVQDVAQKLQYKPSMIASSLRTGKTRSIGLIVEDISNQFFA
DLARVIEDEAKNINYRVFYCSTGDDNDRSEELVQSLLQANVEGFIITPTRNLEKTISQLLKLQKPVVLIDRYFANQKVSH
VVMDNYEGSYSAVKFLISKGRKNIAVVNNKSGMIQMKLREKGYVEALKEEGIYNEKYTLLLDYHSSEKTRIEEIINFFNQ
NKEIDAVLFCANYMGLAGLQAFRTLNYKIPNDISVISFDDHDSFKLHTPTISVIAQPIEDIAVESIQLLMSQMTNFEDFK
IEKVLKKGTLIIRESV

Sequences:

>Translated_336_residues
MKKITIRDIAKQAEVSISTVSFVINGKGEKMAISPAVIKKVQDVAQKLQYKPSMIASSLRTGKTRSIGLIVEDISNQFFA
DLARVIEDEAKNINYRVFYCSTGDDNDRSEELVQSLLQANVEGFIITPTRNLEKTISQLLKLQKPVVLIDRYFANQKVSH
VVMDNYEGSYSAVKFLISKGRKNIAVVNNKSGMIQMKLREKGYVEALKEEGIYNEKYTLLLDYHSSEKTRIEEIINFFNQ
NKEIDAVLFCANYMGLAGLQAFRTLNYKIPNDISVISFDDHDSFKLHTPTISVIAQPIEDIAVESIQLLMSQMTNFEDFK
IEKVLKKGTLIIRESV
>Mature_336_residues
MKKITIRDIAKQAEVSISTVSFVINGKGEKMAISPAVIKKVQDVAQKLQYKPSMIASSLRTGKTRSIGLIVEDISNQFFA
DLARVIEDEAKNINYRVFYCSTGDDNDRSEELVQSLLQANVEGFIITPTRNLEKTISQLLKLQKPVVLIDRYFANQKVSH
VVMDNYEGSYSAVKFLISKGRKNIAVVNNKSGMIQMKLREKGYVEALKEEGIYNEKYTLLLDYHSSEKTRIEEIINFFNQ
NKEIDAVLFCANYMGLAGLQAFRTLNYKIPNDISVISFDDHDSFKLHTPTISVIAQPIEDIAVESIQLLMSQMTNFEDFK
IEKVLKKGTLIIRESV

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=314, Percent_Identity=28.0254777070064, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790369, Length=313, Percent_Identity=25.8785942492013, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1787948, Length=314, Percent_Identity=25.1592356687898, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788474, Length=336, Percent_Identity=24.702380952381, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786268, Length=310, Percent_Identity=24.8387096774194, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787906, Length=328, Percent_Identity=27.4390243902439, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI48994940, Length=316, Percent_Identity=25.3164556962025, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789202, Length=334, Percent_Identity=23.6526946107784, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789068, Length=340, Percent_Identity=24.1176470588235, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790715, Length=317, Percent_Identity=23.3438485804416, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787580, Length=312, Percent_Identity=25.3205128205128, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786540, Length=330, Percent_Identity=21.5151515151515, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38101; Mature: 38101

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKITIRDIAKQAEVSISTVSFVINGKGEKMAISPAVIKKVQDVAQKLQYKPSMIASSLR
CCCEEHHHHHHHHHCEEEEEEEEEECCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHH
TGKTRSIGLIVEDISNQFFADLARVIEDEAKNINYRVFYCSTGDDNDRSEELVQSLLQAN
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCC
VEGFIITPTRNLEKTISQLLKLQKPVVLIDRYFANQKVSHVVMDNYEGSYSAVKFLISKG
CCEEEECCCCCHHHHHHHHHHHCCCEEEEEHHHCCCCHHHHEECCCCCHHHHHHHHHHCC
RKNIAVVNNKSGMIQMKLREKGYVEALKEEGIYNEKYTLLLDYHSSEKTRIEEIINFFNQ
CCCEEEEECCCCEEEEEECCCHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCC
NKEIDAVLFCANYMGLAGLQAFRTLNYKIPNDISVISFDDHDSFKLHTPTISVIAQPIED
CCCHHHEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHH
IAVESIQLLMSQMTNFEDFKIEKVLKKGTLIIRESV
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure
MKKITIRDIAKQAEVSISTVSFVINGKGEKMAISPAVIKKVQDVAQKLQYKPSMIASSLR
CCCEEHHHHHHHHHCEEEEEEEEEECCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHH
TGKTRSIGLIVEDISNQFFADLARVIEDEAKNINYRVFYCSTGDDNDRSEELVQSLLQAN
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCC
VEGFIITPTRNLEKTISQLLKLQKPVVLIDRYFANQKVSHVVMDNYEGSYSAVKFLISKG
CCEEEECCCCCHHHHHHHHHHHCCCEEEEEHHHCCCCHHHHEECCCCCHHHHHHHHHHCC
RKNIAVVNNKSGMIQMKLREKGYVEALKEEGIYNEKYTLLLDYHSSEKTRIEEIINFFNQ
CCCEEEEECCCCEEEEEECCCHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCC
NKEIDAVLFCANYMGLAGLQAFRTLNYKIPNDISVISFDDHDSFKLHTPTISVIAQPIED
CCCHHHEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHH
IAVESIQLLMSQMTNFEDFKIEKVLKKGTLIIRESV
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]