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The map label for this gene is yniC [H]

Identifier: 146300441

GI number: 146300441

Start: 3201038

End: 3201703

Strand: Direct

Name: yniC [H]

Synonym: Fjoh_2690

Alternate gene names: 146300441

Gene position: 3201038-3201703 (Clockwise)

Preceding gene: 146300440

Following gene: 146300450

Centisome position: 52.5

GC content: 38.59

Gene sequence:

>666_bases
ATGTTTGAAGCTGTAATTTTTGATATGGATGGTTTGTTGATTGATTCTGAGCCATTTTGGAGAACCGCAGAAAAAGAAGT
ATTTGGAAGTTTAGGGATTCAGGTAAGGGACGATCTGGCCGTTCAAACCAGCCGAATGACAACAAGAGAGGTCACTGAAT
ATTGGTACAATTATAAACCGTGGAAGCAGAGGGGTCTGCACGAAGTGGAACAAGAGGTGATTGATAGAGTCGGGGAGCTT
ATTGATCATAAAGGGACTATGATGCCAGGAGTTATCGAACTGATTCAGTATTTCAAAAAATTAGGCTGCAAAATAGGGCT
GGCTACAAATTCCCCATACTGCCTTGTTCCCAAAGTACTTAAAAAATTGGAGATCGAAGAGTATTTTGATAGTACCATAT
CAGCAGATTTTGTAGAAAAGCCAAAGCCATACCCTGATATCTATCTAAAAACAGCACTTGAACTTGATGTCAGAGCTGCC
AAATGCATTGTATTTGAAGATTCAAAATCCGGTATAAGTGCTGCTCTTGCCGCTGGTATGAGAGTAGTGGCGGTTCCCGA
ATCAGGAAAATTTTATGATCAAGGGTTTGATATAGCGGATATAAAAATTAGAAAACTTAATGATTTTTGTGATAAACATA
TGAAAATGTTGAATTTAGCTGGTTAG

Upstream 100 bases:

>100_bases
AATTTCTTTATTTTTGACTGGCGGGGAAGAAGCTGGCCATAAAGATTAGTATAAGTAAATAAAAATAATAGTAATGAAAA
ATAACGTAATTGCATCGTAA

Downstream 100 bases:

>100_bases
GCAGTGTTTTCTTTTGTTTTTTTTTTTTGCGATTGTTTTTAGTATTGTTTTGGCCGGTGAGAGGGGAGATGGTAGGATAG
GGAGGTTGATTTGAACGGTA

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MFEAVIFDMDGLLIDSEPFWRTAEKEVFGSLGIQVRDDLAVQTSRMTTREVTEYWYNYKPWKQRGLHEVEQEVIDRVGEL
IDHKGTMMPGVIELIQYFKKLGCKIGLATNSPYCLVPKVLKKLEIEEYFDSTISADFVEKPKPYPDIYLKTALELDVRAA
KCIVFEDSKSGISAALAAGMRVVAVPESGKFYDQGFDIADIKIRKLNDFCDKHMKMLNLAG

Sequences:

>Translated_221_residues
MFEAVIFDMDGLLIDSEPFWRTAEKEVFGSLGIQVRDDLAVQTSRMTTREVTEYWYNYKPWKQRGLHEVEQEVIDRVGEL
IDHKGTMMPGVIELIQYFKKLGCKIGLATNSPYCLVPKVLKKLEIEEYFDSTISADFVEKPKPYPDIYLKTALELDVRAA
KCIVFEDSKSGISAALAAGMRVVAVPESGKFYDQGFDIADIKIRKLNDFCDKHMKMLNLAG
>Mature_221_residues
MFEAVIFDMDGLLIDSEPFWRTAEKEVFGSLGIQVRDDLAVQTSRMTTREVTEYWYNYKPWKQRGLHEVEQEVIDRVGEL
IDHKGTMMPGVIELIQYFKKLGCKIGLATNSPYCLVPKVLKKLEIEEYFDSTISADFVEKPKPYPDIYLKTALELDVRAA
KCIVFEDSKSGISAALAAGMRVVAVPESGKFYDQGFDIADIKIRKLNDFCDKHMKMLNLAG

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates 2-deoxyglucose 6-phosphate and mannose 6- phosphate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=212, Percent_Identity=30.6603773584906, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI207113149, Length=233, Percent_Identity=30.4721030042918, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1788021, Length=213, Percent_Identity=37.5586854460094, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789046, Length=186, Percent_Identity=30.6451612903226, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1789787, Length=231, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1787576, Length=200, Percent_Identity=25, Blast_Score=69, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17137324, Length=193, Percent_Identity=27.979274611399, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 25178; Mature: 25178

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEAVIFDMDGLLIDSEPFWRTAEKEVFGSLGIQVRDDLAVQTSRMTTREVTEYWYNYKP
CCCEEEEECCCEEECCCCCHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHCCCCC
WKQRGLHEVEQEVIDRVGELIDHKGTMMPGVIELIQYFKKLGCKIGLATNSPYCLVPKVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCCCEEEHHHHH
KKLEIEEYFDSTISADFVEKPKPYPDIYLKTALELDVRAAKCIVFEDSKSGISAALAAGM
HHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHCCE
RVVAVPESGKFYDQGFDIADIKIRKLNDFCDKHMKMLNLAG
EEEEECCCCCHHHCCCCEEHEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFEAVIFDMDGLLIDSEPFWRTAEKEVFGSLGIQVRDDLAVQTSRMTTREVTEYWYNYKP
CCCEEEEECCCEEECCCCCHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHCCCCC
WKQRGLHEVEQEVIDRVGELIDHKGTMMPGVIELIQYFKKLGCKIGLATNSPYCLVPKVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCCCEEEHHHHH
KKLEIEEYFDSTISADFVEKPKPYPDIYLKTALELDVRAAKCIVFEDSKSGISAALAAGM
HHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHCCE
RVVAVPESGKFYDQGFDIADIKIRKLNDFCDKHMKMLNLAG
EEEEECCCCCHHHCCCCEEHEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]