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The map label for this gene is dinB [H]

Identifier: 146300403

GI number: 146300403

Start: 3151860

End: 3152270

Strand: Reverse

Name: dinB [H]

Synonym: Fjoh_2651

Alternate gene names: 146300403

Gene position: 3152270-3151860 (Counterclockwise)

Preceding gene: 146300405

Following gene: 146300402

Centisome position: 51.7

GC content: 50.36

Gene sequence:

>411_bases
ATGATAAAGATTATGAACCGGGCTATTGTACACATTGACATGAACACCTTTTTCGTCTCCTGCGAAAGGCTTACCAATTC
AGAGCTTAACGGCATTCCGCTCATTATCGGCGGGGGCGAGCGTGGCGTTGTAGCCTCCTGCTCCTATGAGGCGCGGCGTT
TCGGGGTGCGCTCGGCAATGCCCATCCAGATGGCGCTCAGGCTTTGTCCGCAGGCCAAAGTGATGAAAGGCGATATGGAA
CTCTATTCAAGGCTCTCCCATGATGTTACAGAAATTATTCAGGAAAAAGCCCCGGTGGTGGAAAAGGCCTCTATTGATGA
ATTCTATCTGGACATTACCGGAATGGACAAATTCTACGGCAGCTACAAGTGGACCGACGAGCTGGCGCAGCGCATCCGAA
ATAAATACTAA

Upstream 100 bases:

>100_bases
AGACCGCCTGTAAAATCAGTGCTTCTATTTTTTGTTACTATTTAGAACATTATGTTTTCATAAAATTGTTATTATCTGTA
CTAATTTTGACAGGTATAAA

Downstream 100 bases:

>100_bases
ATGTGTGCCTTACATTTTTCTCTCAACCTCAAGGAATCCGGAAAATGTTGTCAAAGCCTACAACTGCAATGTGCAGGGCT
ATTTTAAGAAAGAAGAAGAT

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MIKIMNRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGERGVVASCSYEARRFGVRSAMPIQMALRLCPQAKVMKGDME
LYSRLSHDVTEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKWTDELAQRIRNKY

Sequences:

>Translated_136_residues
MIKIMNRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGERGVVASCSYEARRFGVRSAMPIQMALRLCPQAKVMKGDME
LYSRLSHDVTEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKWTDELAQRIRNKY
>Mature_136_residues
MIKIMNRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGERGVVASCSYEARRFGVRSAMPIQMALRLCPQAKVMKGDME
LYSRLSHDVTEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKWTDELAQRIRNKY

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=125, Percent_Identity=36.8, Blast_Score=89, Evalue=8e-19,
Organism=Homo sapiens, GI7705344, Length=109, Percent_Identity=39.4495412844037, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786425, Length=130, Percent_Identity=41.5384615384615, Blast_Score=104, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193205700, Length=109, Percent_Identity=32.1100917431193, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534089, Length=126, Percent_Identity=34.9206349206349, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21355641, Length=110, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24644984, Length=110, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 15532; Mature: 15532

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIMNRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGERGVVASCSYEARRFGVRSAM
CEEECCEEEEEEECHHHEEEHHHHCCCCCCCEEEEEECCCCCEEEECCHHHHHHCCCCCC
PIQMALRLCPQAKVMKGDMELYSRLSHDVTEIIQEKAPVVEKASIDEFYLDITGMDKFYG
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCHHHHC
SYKWTDELAQRIRNKY
CCCCHHHHHHHHHCCC
>Mature Secondary Structure
MIKIMNRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGERGVVASCSYEARRFGVRSAM
CEEECCEEEEEEECHHHEEEHHHHCCCCCCCEEEEEECCCCCEEEECCHHHHHHCCCCCC
PIQMALRLCPQAKVMKGDMELYSRLSHDVTEIIQEKAPVVEKASIDEFYLDITGMDKFYG
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCHHHHC
SYKWTDELAQRIRNKY
CCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA